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Axsome Therapeutics, Inc.

AXSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001579428

In the last 90 days, Axsome Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 505 institutions reported holding it in 13F filings for Q2 2026, worth $9.34B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Axsome Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
355
+10 vs. Q2 2025
Shares held
37.2M
−189.7K (−0.5%) vs. Q2 2025
Total value
$4.51B
+$613.1M (+15.7%) vs. Q2 2025
New holders
49
146 more added
Sold out
39
104 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AXSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 355 institutions
Q1 2021: 184 institutionsQ2 2021: 176 institutionsQ3 2021: 171 institutionsQ4 2021: 167 institutionsQ1 2022: 175 institutionsQ2 2022: 174 institutionsQ3 2022: 188 institutionsQ4 2022: 219 institutionsQ1 2023: 197 institutionsQ2 2023: 231 institutionsQ3 2023: 227 institutionsQ4 2023: 245 institutionsQ1 2024: 259 institutionsQ2 2024: 257 institutionsQ3 2024: 280 institutionsQ4 2024: 292 institutionsQ1 2025: 353 institutionsQ2 2025: 348 institutionsQ3 2025: 355 institutionsQ4 2025: 399 institutionsQ1 2026: 410 institutionsQ2 2026: 505 institutions
Value heldQ3 2025: $4.51B
Q1 2021: $1.31BQ2 2021: $1.51BQ3 2021: $627.3MQ4 2021: $704.2MQ1 2022: $787.4MQ2 2022: $826.7MQ3 2022: $1.15BQ4 2022: $2.32BQ1 2023: $1.97BQ2 2023: $2.61BQ3 2023: $2.65BQ4 2023: $3.07BQ1 2024: $3.09BQ2 2024: $3.28BQ3 2024: $3.48BQ4 2024: $3.15BQ1 2025: $4.37BQ2 2025: $3.95BQ3 2025: $4.51BQ4 2025: $6.86BQ1 2026: $6.41BQ2 2026: $9.34B
Institutions holding AXSM and their total value by quarter
QuarterHoldersValue
Q2 2026505$9.34B
Q1 2026410$6.41B
Q4 2025399$6.86B
Q3 2025355$4.51B
Q2 2025348$3.95B
Q1 2025353$4.37B
Q4 2024292$3.15B
Q3 2024280$3.48B
Q2 2024257$3.28B
Q1 2024259$3.09B
Q4 2023245$3.07B
Q3 2023227$2.65B
Q2 2023231$2.61B
Q1 2023197$1.97B
Q4 2022219$2.32B
Q3 2022188$1.15B
Q2 2022174$826.7M
Q1 2022175$787.4M
Q4 2021167$704.2M
Q3 2021171$627.3M
Q2 2021176$1.51B
Q1 2021184$1.31B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Axsome Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding AXSM in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
EverSource Wealth Advisors, LLC355$43.1K0.00%+41+13.1%Added
Walleye Trading LLC339$41.2K0.00%−1,777−84.0%Reduced
Advisory Services Network, LLC330$40.1K0.00%+330New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.326$40.0K0.00%00.0%Unchanged
Essex Investment Management Co LLC317$38.5K0.01%+317New
MAI Capital Management291$35.3K0.00%00.0%Unchanged
Optiver Holding B.V.288$35.0K0.00%+130+82.3%Added
First Horizon Corp276$33.5K0.00%+276New
Washington Trust Advisors, Inc.250$30.4K0.00%00.0%Unchanged
Jones Financial Companies LLLP252$29.5K0.00%−52−17.1%Reduced
Signaturefd, LLC229$27.8K0.00%00.0%Unchanged
Huntington National Bank228$27.7K0.00%+29+14.6%Added
Fifth Third Bancorp212$25.7K0.00%+12+6.0%Added
Versant Capital Management, Inc204$24.8K0.00%+203+20,300.0%Added
Smartleaf Asset Management LLC199$23.4K0.00%+84+73.0%Added
Essential Partners LLC192$23.3K0.01%−24−11.1%Reduced
Daiwa Securities Group Inc.165$20.0K0.00%−12−6.8%Reduced
GAMMA Investing LLC162$19.7K0.00%+98+153.1%Added
Quadrant Capital Group LLC135$16.4K0.00%+135New
Danske Bank A/S100$12.1K0.00%00.0%Unchanged
Sterling Capital Management LLC98$11.9K0.00%00.0%Unchanged
Global Retirement Partners, LLC85$10.3K0.00%00.0%Unchanged
Rise Advisors, LLC80$9.72K0.00%00.0%Unchanged
JPL Wealth Management, LLC76$9.23K0.00%+76New
True Wealth Design, LLC75$9.11K0.00%+30+66.7%Added
WPG Advisers, LLC70$8.50K0.01%+1+1.4%Added
Rothschild Investment LLC60$7.29K0.00%−20−25.0%Reduced
Harbour Investments, Inc.60$7.29K0.00%00.0%Unchanged
Massmutual Trust Co FSB53$6.44K0.00%−53−50.0%Reduced
Orion Capital Management LLC50$6.07K0.00%00.0%Unchanged
Larson Financial Group LLC44$5.34K0.00%+43+4,300.0%Added
Private Trust Co NA41$4.98K0.00%00.0%Unchanged
Farther Finance Advisors, LLC39$4.74K0.00%+10+34.5%Added
Principal Securities, Inc.33$4.01K0.00%+5+17.9%Added
LRI Investments, LLC31$3.78K0.00%+8+34.8%Added
Rakuten Securities, Inc.30$3.64K0.00%+4+15.4%Added
Meeder Asset Management Inc28$3.40K0.00%+28New
Parkside Financial Bank & Trust23$2.79K0.00%00.0%Unchanged
SBI Securities Co., Ltd.21$2.55K0.00%+2+10.5%Added
Bare Financial Services, Inc21$2.55K0.00%+11+110.0%Added
AdvisorNet Financial, Inc20$2.43K0.00%+20New
GPS Wealth Strategies Group, LLC18$2.19K0.00%00.0%Unchanged
Geneos Wealth Management Inc.16$1.94K0.00%−34−68.0%Reduced
North Star Investment Management Corp.13$1.58K0.00%00.0%Unchanged
Parallel Advisors, LLC12$1.46K0.00%00.0%Unchanged
Bell Investment Advisors, Inc11$1.34K0.00%−5−31.3%Reduced
UMA Financial Services, Inc.10$1.22K0.00%−4−28.6%Reduced
Steward Partners Investment Advisory, LLC10$1.22K0.00%00.0%Unchanged
Montag A & Associates Inc8$9720.00%+8New
GHP Investment Advisors, Inc.6$7290.00%+6New
Cornerstone Planning Group LLC5$6660.00%00.0%Unchanged
Sunbelt Securities, Inc.2$2430.00%+2New
TFC Financial Management1$1220.00%00.0%Unchanged
Atlantic Union Bankshares Corp1$1220.00%+1New
Concord Wealth Partners1$1210.00%00.0%Unchanged
Bridgewater Associates, LP0$00.00%−107,292−100.0%Sold out
Avidity Partners Management LP0$00.00%−94,500−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−76,727−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−50,000−100.0%Sold out
Schroder Investment Management Group0$00.00%−37,481−100.0%Sold out
Point72 Europe (London) LLP0$00.00%−33,824−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−25,037−100.0%Sold out
Magnetar Financial LLC0$00.00%−20,315−100.0%Sold out
Quadrature Capital Ltd0$00.00%−16,459−100.0%Sold out
Winton Group Ltd0$00.00%−9,555−100.0%Sold out
Virtue Capital Management, LLC0$00.00%−6,807−100.0%Sold out
UBS Oconnor LLC0$00.00%−6,400−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−6,300−100.0%Sold out
Knott David M Jr0$00.00%−6,000−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−5,000−100.0%Sold out
Aigen Investment Management, LP0$00.00%−4,063−100.0%Sold out
Polen Capital Management LLC0$00.00%−3,232−100.0%Sold out
Qsemble Capital Management, LP0$00.00%−2,681−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−2,500−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−2,490−100.0%Sold out
Mount Yale Investment Advisors, LLC0$00.00%−2,366−100.0%Sold out
NEOS Investment Management LLC0$00.00%−2,327−100.0%Sold out
Tema ETFs LLC0$00.00%−2,327−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−2,228−100.0%Sold out
Whalen Wealth Management Inc.0$00.00%−2,168−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−2,100−100.0%Sold out
Marex Group plc0$00.00%−2,062−100.0%Sold out
Options Solutions, LLC0$00.00%−2,022−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−2,000−100.0%Sold out
Raiffeisen Bank International AG0$00.00%−600−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−289−100.0%Sold out
Transce3nd, LLC0$00.00%−209−100.0%Sold out
State of Wyoming0$00.00%−146−100.0%Sold out
Skopos Labs, Inc.0$00.00%−37−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−37−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−27−100.0%Sold out
Bryn Mawr Trust Co0$00.00%−16−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−10−100.0%Sold out
Wolff Wiese Magana LLC0$00.00%−10−100.0%Sold out
Norges Bank––––Not filed
CIBC World Markets Corp––––Not filed
Avantax Advisory Services, Inc.––––Not filed