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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q1 2024

Institutional positions in Applied Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
89
+6 vs. Q4 2023
Shares held
94.0M
+32.5M (+52.9%) vs. Q4 2023
Total value
$638.6M
+$432.8M (+210.2%) vs. Q4 2023
New holders
30
34 more added
Sold out
24
17 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 89 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2024: $638.6M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q4 2023.

Institutions holding APLT in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Franklin Resources Inc10,564,345$71.8M0.02%+3,546,433+50.5%Added
VR Adviser, LLC9,075,000$61.7M2.94%+2,825,000+45.2%Added
Perceptive Advisors LLC8,005,000$54.4M0.96%+3,924,751+96.2%Added
Janus Henderson Group PLC6,414,642$43.6M0.02%+4,266,179+198.6%Added
Propel Bio Management, LLC6,111,906$41.6M24.19%+736,924+13.7%Added
Knoll Capital Management, LLC5,574,687$37.9M23.58%+100,000+1.8%Added
Vestal Point Capital, LP5,110,000$34.7M2.87%+955,000+23.0%Added
Morgan Stanley3,194,052$21.7M0.00%+3,140,429+5,856.5%Added
Vanguard Group Inc3,010,290$20.5M0.00%−220,191−6.8%Reduced
Simplify Asset Management Inc.2,817,505$19.2M1.84%+400,000+16.5%Added
Adage Capital Partners GP, L.L.C.2,649,784$18.0M0.03%+2,649,784New
Tang Capital Management LLC2,230,000$15.2M1.58%+2,230,000New
StemPoint Capital LP2,017,016$13.7M3.66%+1,109,864+122.3%Added
Frazier Life Sciences Management, L.P.1,952,857$13.3M0.56%+1,952,857New
Parkman Healthcare Partners LLC1,854,763$12.6M1.55%+835,607+82.0%Added
Schonfeld Strategic Advisors LLC1,836,642$12.5M0.10%+1,345,151+273.7%Added
Opaleye Management Inc.1,770,000$12.0M2.62%+677,500+62.0%Added
Soleus Capital Management, L.P.1,564,916$10.6M0.93%+1,104,123+239.6%Added
Rock Springs Capital Management LP1,497,918$10.2M0.26%+602,723+67.3%Added
Laurion Capital Management LP1,481,006$10.1M0.28%+1,050,000+243.6%Added
Alyeska Investment Group, L.P.1,442,926$9.77M0.06%−1,161,793−44.6%Reduced
Logos Global Management LP1,350,000$8.98M0.94%−310,000−18.7%Reduced
Artal Group S.A.1,009,500$6.86M0.18%+1,009,500New
BlackRock Inc.989,277$6.73M0.00%+461,391+87.4%Added
Millennium Management LLC926,425$6.30M0.01%+326,387+54.4%Added
Acuta Capital Partners, LLC792,000$5.39M3.50%+266,900+50.8%Added
Goldman Sachs Group Inc715,208$4.86M0.00%+698,456+4,169.4%Added
Deutsche Bank AG622,227$4.23M0.00%+622,227New
Sphera Funds Management Ltd.619,029$4.21M0.68%+619,029New
Geode Capital Management, LLC604,428$4.11M0.00%+26,757+4.6%Added
Invesco Ltd.539,857$3.67M0.00%+539,857New
Susquehanna International Group, LLP484,885$3.30M0.00%−82,560−14.5%Reduced
Qube Research & Technologies Ltd459,141$3.12M0.01%+265,468+137.1%Added
ADAR1 Capital Management, LLC456,588$3.10M0.85%+456,588New
Walleye Capital LLC308,316$2.10M0.02%+291,316+1,713.6%Added
Altitude Crest Partners Inc.259,700$1.77M0.76%+259,700New
Jane Street Group, LLC244,612$1.66M0.00%+112,706+85.4%Added
Checkpoint Capital L.P.220,000$1.50M1.00%+220,000New
State Street Corp206,669$1.41M0.00%+66,000+46.9%Added
Squarepoint Ops LLC193,758$1.32M0.01%+179,843+1,292.4%Added
JPMorgan Chase & Co178,924$1.22M0.00%+131,991+281.2%Added
Renaissance Technologies LLC175,800$1.20M0.00%−477,287−73.1%Reduced
Bridgeway Capital Management, LLC173,800$1.18M0.02%−20,000−10.3%Reduced
Cubist Systematic Strategies, LLC163,072$1.11M0.01%+104,475+178.3%Added
Two Sigma Investments, LP155,158$1.06M0.00%−130,839−45.7%Reduced
Man Group plc154,636$1.05M0.00%−11,914−7.2%Reduced
UBS Group AG152,760$1.04M0.00%+32,553+27.1%Added
Rockefeller Capital Management L.P.150,000$1.02M0.00%+150,000New
J. Goldman & Co LP146,392$995.5K0.05%+146,392New
Citigroup Inc118,804$807.9K0.00%−101,122−46.0%Reduced
Northern Trust Corp106,453$723.9K0.00%−144−0.1%Reduced
HRT Financial LP98,879$672.0K0.00%+98,879New
EAM Investors, LLC92,872$631.5K0.10%−89,998−49.2%Reduced
Omers Administration Corp64,700$440.0K0.01%+51,600+393.9%Added
Richmond Brothers, Inc.61,827$420.4K0.78%−61,827−50.0%Reduced
Barclays PLC61,272$416.6K0.00%+61,272New
ExodusPoint Capital Management, LP60,795$413.0K0.01%+60,795New
Marathon Trading Investment Management LLC59,000$401.2K0.16%+59,000New
Brevan Howard Capital Management LP47,356$322.0K0.03%+47,356New
Jump Financial, LLC43,569$296.3K0.01%+19,398+80.3%Added
EntryPoint Capital, LLC40,070$272.5K0.24%+40,070New
Relyea Zuckerberg Hanson LLC40,000$272.0K0.05%00.0%Unchanged
Engineers Gate Manager LP39,631$269.5K0.01%+39,631New
Point72 Asia (Singapore) Pte. Ltd.37,145$252.6K0.07%+34,245+1,180.9%Added
Bank of America Corp35,545$241.7K0.00%−9,086−20.4%Reduced
Denali Advisors LLC33,600$228.5K0.07%+33,600New
Caption Management, LLC31,300$212.8K0.02%+31,300New
LMR Partners LLP28,013$190.5K0.00%+28,013New
Y-Intercept (Hong Kong) Ltd27,017$183.7K0.01%+15,969+144.5%Added
Polymer Capital Management (HK) LTD25,826$175.6K0.04%+25,826New
Charles Schwab Investment Management Inc24,504$166.6K0.00%00.0%Unchanged
Jefferies Financial Group Inc.22,200$151.0K0.00%+22,200New
Gsa Capital Partners LLP21,431$146.0K0.01%+21,431New
WealthTrust Axiom LLC21,000$142.8K0.05%−22,000−51.2%Reduced
Susquehanna Portfolio Strategies, LLC14,099$95.9K0.00%−10,996−43.8%Reduced
Commonwealth Equity Services, LLC13,550$92.0K0.00%00.0%Unchanged
Perennial Investment Advisors, LLC11,600$78.9K0.01%00.0%Unchanged
Prudential Financial Inc11,300$76.8K0.00%+11,300New
Raymond James & Associates10,658$72.5K0.00%+10,658New
CTC Alternative Strategies, Ltd.10,400$70.7K0.04%+10,400New
Tower Research Capital LLC (TRC)10,261$69.8K0.00%−12,914−55.7%Reduced
Citadel Advisors LLC3,109$21.1K0.00%−74,503−96.0%Reduced
Comerica Bank2,000$13.6K0.00%00.0%Unchanged
Cutler Group LP700$4.00K0.00%+700New
Rhumbline Advisers544$3.70K0.00%00.0%Unchanged
Wells Fargo & Company435$2.96K0.00%+7+1.6%Added
Federation des caisses Desjardins du Quebec84$5710.00%00.0%Unchanged
Macquarie Group Ltd6,736$460.00%+6,736New
BNP Paribas Arbitrage, SA1$70.00%00.0%Unchanged
FMR LLC0$00.00%−2,427,436−100.0%Sold out
AIGH Capital Management LLC0$00.00%−1,659,039−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−474,929−100.0%Sold out
Worth Venture Partners, LLC0$00.00%−412,981−100.0%Sold out
Marshall Wace, LLP0$00.00%−258,144−100.0%Sold out
683 Capital Management, LLC0$00.00%−100,806−100.0%Sold out
XTX Topco Ltd0$00.00%−81,371−100.0%Sold out
Connective Capital Management, LLC0$00.00%−79,242−100.0%Sold out
Simplex Trading, LLC0$00.00%−71,991−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−51,000−100.0%Sold out
Maven Securities LTD0$00.00%−50,000−100.0%Sold out