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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q4 2023

Institutional positions in Applied Therapeutics, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
83
+28 vs. Q3 2023
Shares held
61.4M
+18.5M (+43.0%) vs. Q3 2023
Total value
$205.8M
+$98.8M (+92.4%) vs. Q3 2023
New holders
32
27 more added
Sold out
4
11 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 83 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2023: $205.8M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q3 2023.

Institutions holding APLT in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Franklin Resources Inc7,017,912$23.5M0.01%−929,100−11.7%Reduced
VR Adviser, LLC6,250,000$20.9M1.44%+591,966+10.5%Added
Knoll Capital Management, LLC5,474,687$18.3M15.19%+312,599+6.1%Added
Propel Bio Management, LLC5,374,982$18.0M14.93%+5,374,982New
Vestal Point Capital, LP4,155,000$13.9M1.47%+4,155,000New
Perceptive Advisors LLC4,080,249$13.7M0.31%+4,080,249New
Vanguard Group Inc3,230,481$10.8M0.00%+1,801,827+126.1%Added
Alyeska Investment Group, L.P.2,604,719$8.73M0.06%−1,615,941−38.3%Reduced
FMR LLC2,427,436$8.13M0.00%−212,100−8.0%Reduced
Simplify Asset Management Inc.2,417,505$8.10M1.26%00.0%Unchanged
Janus Henderson Group PLC2,148,463$7.19M0.00%+2,148,463New
Logos Global Management LP1,660,000$5.56M0.62%+1,660,000New
AIGH Capital Management LLC1,659,039$5.56M2.20%+865,689+109.1%Added
Opaleye Management Inc.1,092,500$3.66M0.98%+199,500+22.3%Added
Parkman Healthcare Partners LLC1,019,156$3.41M0.48%−730,844−41.8%Reduced
StemPoint Capital LP907,152$3.04M0.82%+907,152New
Rock Springs Capital Management LP895,195$3.00M0.07%+86,386+10.7%Added
Renaissance Technologies LLC653,087$2.19M0.00%+237,609+57.2%Added
Millennium Management LLC600,038$2.01M0.00%+600,038New
Geode Capital Management, LLC577,671$1.94M0.00%+134,199+30.3%Added
Susquehanna International Group, LLP567,445$1.90M0.00%+473,653+505.0%Added
BlackRock Inc.527,886$1.77M0.00%+143,893+37.5%Added
Acuta Capital Partners, LLC525,100$1.76M0.99%+525,100New
Schonfeld Strategic Advisors LLC491,491$1.65M0.01%+34,091+7.5%Added
Point72 Asset Management, L.P.474,929$1.59M0.00%00.0%Unchanged
Soleus Capital Management, L.P.460,793$1.54M0.17%−731,833−61.4%Reduced
Laurion Capital Management LP431,006$1.44M0.05%+85,106+24.6%Added
Worth Venture Partners, LLC412,981$1.38M0.75%+219,008+112.9%Added
Two Sigma Investments, LP285,997$958.1K0.00%+216,646+312.4%Added
Marshall Wace, LLP258,144$864.8K0.00%+258,144New
Citigroup Inc219,926$736.8K0.00%+153,950+233.3%Added
Bridgeway Capital Management, LLC193,800$649.2K0.01%+50,000+34.8%Added
Qube Research & Technologies Ltd193,673$648.8K0.00%+186,123+2,465.2%Added
EAM Investors, LLC182,870$612.6K0.11%−208,725−53.3%Reduced
Man Group plc166,550$557.9K0.00%+166,550New
State Street Corp140,669$471.2K0.00%+3,400+2.5%Added
Jane Street Group, LLC131,906$441.9K0.00%−71,273−35.1%Reduced
Richmond Brothers, Inc.123,654$414.2K0.72%00.0%Unchanged
UBS Group AG120,207$402.7K0.00%+11,826+10.9%Added
Northern Trust Corp106,597$357.1K0.00%+7,650+7.7%Added
683 Capital Management, LLC100,806$337.7K0.03%+100,806New
XTX Topco Ltd81,371$272.6K0.06%+81,371New
Connective Capital Management, LLC79,242$265.5K0.23%+79,242New
Citadel Advisors LLC77,612$260.0K0.00%+77,239+20,707.5%Added
Simplex Trading, LLC71,991$241.0K0.01%+71,991New
Cubist Systematic Strategies, LLC58,597$196.3K0.00%+54,085+1,198.7%Added
Morgan Stanley53,623$179.6K0.00%+2,252+4.4%Added
Two Sigma Advisers, LP51,000$170.8K0.00%+35,400+226.9%Added
Maven Securities LTD50,000$167.5K0.02%+50,000New
JPMorgan Chase & Co46,933$157.2K0.00%+46,545+11,996.1%Added
Bank of America Corp44,631$149.5K0.00%+44,403+19,475.0%Added
WealthTrust Axiom LLC43,000$144.1K0.05%00.0%Unchanged
Relyea Zuckerberg Hanson LLC40,000$134.0K0.03%00.0%Unchanged
Bank of New York Mellon Corp26,960$90.3K0.00%+26,960New
Susquehanna Portfolio Strategies, LLC25,095$84.1K0.00%+25,095New
Boothbay Fund Management, LLC24,964$83.6K0.00%+24,964New
Charles Schwab Investment Management Inc24,504$82.1K0.00%00.0%Unchanged
Jump Financial, LLC24,171$81.0K0.00%+24,171New
Tower Research Capital LLC (TRC)23,175$77.6K0.00%−12,268−34.6%Reduced
Two Sigma Securities, LLC18,687$62.6K0.00%+18,687New
Belvedere Trading LLC18,236$61.1K0.01%+18,236New
US Bancorp18,091$60.6K0.00%00.0%Unchanged
Walleye Capital LLC17,000$57.0K0.00%−122,381−87.8%Reduced
Goldman Sachs Group Inc16,752$56.1K0.00%+16,752New
Group One Trading, L.P.16,445$55.1K0.00%+16,445New
Squarepoint Ops LLC13,915$46.6K0.00%+13,915New
Commonwealth Equity Services, LLC13,550$45.0K0.00%00.0%Unchanged
Acadian Asset Management LLC13,689$45.0K0.00%+13,689New
Omers Administration Corp13,100$43.9K0.00%+13,100New
Perennial Investment Advisors, LLC11,600$38.9K0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd11,048$37.0K0.00%+11,048New
Balyasny Asset Management LLC10,605$35.5K0.00%+10,605New
Wolverine Trading, LLC10,105$33.9K0.00%+10,105New
Intrua Financial, LLC10,040$33.6K0.01%+10,040New
Essex Financial Services, Inc.10,000$33.5K0.00%00.0%Unchanged
Vontobel Holding Ltd.10,000$33.5K0.00%+10,000New
Point72 Asia (Singapore) Pte. Ltd.2,900$9.71K0.00%+2,900New
Royal Bank of Canada2,141$7.00K0.00%+2,059+2,511.0%Added
Comerica Bank2,000$6.70K0.00%00.0%Unchanged
Rhumbline Advisers544$1.82K0.00%00.0%Unchanged
Wells Fargo & Company428$1.43K0.00%−76−15.1%Reduced
Federation des caisses Desjardins du Quebec84$2810.00%00.0%Unchanged
BNP Paribas Arbitrage, SA1$30.00%−1,632−99.9%Reduced
Armistice Capital, LLC0$00.00%−3,400,000−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−63,508−100.0%Sold out
Ground Swell Capital, LLC0$00.00%−12,349−100.0%Sold out
HRT Financial LP0$00.00%−11,852−100.0%Sold out