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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q1 2022

Institutional positions in Applied Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
71
+2 vs. Q4 2021
Shares held
12.4M
−2.57M (−17.2%) vs. Q4 2021
Total value
$26.0M
−$107.5M (−80.5%) vs. Q4 2021
New holders
15
19 more added
Sold out
13
19 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 71 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2022: $26.0M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q4 2021.

Institutions holding APLT in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Point72 Asset Management, L.P.2,549,000$5.38M0.02%+1,435,000+128.8%Added
Franklin Resources Inc1,595,550$3.37M0.00%+470,256+41.8%Added
BlackRock Inc.1,363,403$2.88M0.00%+64,872+5.0%Added
Knoll Capital Management, LLC1,082,123$2.28M1.43%+50,000+4.8%Added
FMR LLC903,293$1.91M0.00%−1,340,183−59.7%Reduced
Rock Springs Capital Management LP701,680$1.48M0.04%00.0%Unchanged
Vanguard Group Inc610,867$1.29M0.00%−240,271−28.2%Reduced
State Street Corp426,404$900.0K0.00%+84,753+24.8%Added
Artal Group S.A.400,000$844.0K0.04%00.0%Unchanged
Geode Capital Management, LLC287,930$607.0K0.00%−15,313−5.0%Reduced
Renaissance Technologies LLC282,200$595.0K0.00%+264,600+1,503.4%Added
Two Sigma Investments, LP280,273$591.0K0.00%+251,842+885.8%Added
Northern Trust Corp164,383$347.0K0.00%−13,298−7.5%Reduced
D. E. Shaw & Co., Inc.146,423$309.0K0.00%+146,423New
Kore Private Wealth LLC125,000$264.0K0.03%00.0%Unchanged
Bridgeway Capital Management, LLC108,800$230.0K0.00%+108,800New
Millennium Management LLC108,096$228.0K0.00%+37,735+53.6%Added
Two Sigma Advisers, LP105,100$222.0K0.00%+92,200+714.7%Added
Goldman Sachs Group Inc94,664$200.0K0.00%+19,159+25.4%Added
AQR Capital Management LLC85,064$179.0K0.00%+85,064New
First Manhattan Co73,783$155.0K0.00%00.0%Unchanged
Bank of New York Mellon Corp70,458$149.0K0.00%+2,062+3.0%Added
Walleye Capital LLC52,273$110.0K0.00%+41,073+366.7%Added
HRT Financial LP48,737$102.0K0.00%+48,737New
Nuveen Asset Management, LLC53,840$98.0K0.00%−8,167−13.2%Reduced
Dimensional Fund Advisors LP39,310$83.0K0.00%−33,615−46.1%Reduced
Charles Schwab Investment Management Inc38,968$83.0K0.00%−6,111−13.6%Reduced
Swiss National Bank37,300$79.0K0.00%00.0%Unchanged
Occudo Quantitative Strategies LP34,372$73.0K0.01%+34,372New
Acadian Asset Management LLC33,345$70.0K0.00%+33,345New
Deutsche Bank AG31,910$67.0K0.00%+20,505+179.8%Added
Schonfeld Strategic Advisors LLC30,500$65.0K0.00%+30,500New
Algert Global LLC28,420$60.0K0.00%+28,420New
Parametric Portfolio Associates LLC26,981$57.0K0.00%+26,981New
Connor, Clark & Lunn Investment Management Ltd.25,015$53.0K0.00%+25,015New
UBS Asset Management Americas Inc22,695$47.9K0.00%00.0%Unchanged
UBS Group AG22,013$47.0K0.00%−52,408−70.4%Reduced
California State Teachers Retirement System22,271$47.0K0.00%−1,754−7.3%Reduced
Bank of America Corp20,188$43.0K0.00%−15,843−44.0%Reduced
Morgan Stanley20,426$43.0K0.00%+1,617+8.6%Added
ACT Capital Management, LLC20,000$42.0K0.04%00.0%Unchanged
JustInvest LLC20,119$42.0K0.00%+20,119New
State of Wisconsin Investment Board18,900$40.0K0.00%00.0%Unchanged
Rhumbline Advisers17,409$37.0K0.00%−706−3.9%Reduced
Citadel Advisors LLC16,685$35.0K0.00%+6,027+56.5%Added
Alliancebernstein L.P.12,500$26.0K0.00%00.0%Unchanged
New York State Common Retirement Fund12,340$26.0K0.00%00.0%Unchanged
JPMorgan Chase & Co11,550$25.0K0.00%+2,292+24.8%Added
Credit Suisse AG11,184$23.0K0.00%+829+8.0%Added
American International Group, Inc.8,793$19.0K0.00%−620−6.6%Reduced
Simplex Trading, LLC8,034$16.0K0.00%+2,606+48.0%Added
Tower Research Capital LLC (TRC)5,862$13.0K0.00%+1,593+37.3%Added
Legal & General Group Plc5,618$12.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC4,038$9.00K0.00%−3,388−45.6%Reduced
Barclays PLC3,988$8.00K0.00%−17,510−81.4%Reduced
Citigroup Inc2,801$6.00K0.00%−2,702−49.1%Reduced
Amalgamated Bank2,828$6.00K0.00%+2,828New
Amalgamated Financial Corp.2,828$6.00K0.00%+2,828New
Ancora Advisors, LLC2,500$5.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA1,539$3.25K0.00%−3,311−68.3%Reduced
Wells Fargo & Company1,465$3.00K0.00%−6,255−81.0%Reduced
Group One Trading, L.P.1,186$3.00K0.00%−2,343−66.4%Reduced
Royal Bank of Canada1,089$2.00K0.00%−3,288−75.1%Reduced
Ameritas Investment Partners, Inc.1,179$2.00K0.00%00.0%Unchanged
Great West Life Assurance Co997$2.00K0.00%00.0%Unchanged
Point72 Hong Kong Ltd550$1.00K0.00%00.0%Unchanged
Macquarie Group Ltd393$1.00K0.00%00.0%Unchanged
Federated Hermes, Inc.519$1.00K0.00%+519New
Federation des caisses Desjardins du Quebec84$1770.00%00.0%Unchanged
Daiwa Securities Group Inc.42$00.00%00.0%Unchanged
Cutler Group LP220$00.00%+220New
OrbiMed Advisors LLC0$00.00%−2,313,681−100.0%Sold out
Emerald Mutual Fund Advisers Trust0$00.00%−631,922−100.0%Sold out
Emerald Advisers, LLC0$00.00%−611,525−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−517,107−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−75,800−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−60,463−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−11,940−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−11,189−100.0%Sold out
Trexquant Investment LP0$00.00%−11,091−100.0%Sold out
Denali Advisors LLC0$00.00%−2,800−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−800−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−113−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−50−100.0%Sold out