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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q3 2021

Institutional positions in Applied Therapeutics, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
70
+1 vs. Q2 2021
Shares held
15.1M
−258.5K (−1.7%) vs. Q2 2021
Total value
$250.9M
−$68.4M (−21.4%) vs. Q2 2021
New holders
8
21 more added
Sold out
7
18 more reduced

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 70 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2021: $250.9M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q2 2021.

Institutions holding APLT in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC2,410,247$40.0M0.00%−9,593−0.4%Reduced
OrbiMed Advisors LLC2,257,387$37.5M0.42%00.0%Unchanged
BlackRock Inc.1,292,817$21.5M0.00%−19,285−1.5%Reduced
Knoll Capital Management, LLC1,032,123$17.1M8.54%00.0%Unchanged
Point72 Asset Management, L.P.1,015,271$16.9M0.08%+522,771+106.1%Added
Vanguard Group Inc850,299$14.1M0.00%+5,417+0.6%Added
Franklin Resources Inc834,282$13.8M0.01%+4,300+0.5%Added
Rock Springs Capital Management LP701,680$11.6M0.24%00.0%Unchanged
Driehaus Capital Management LLC639,557$10.6M0.13%−4,633−0.7%Reduced
Alkeon Capital Management LLC639,458$10.6M0.04%−401,876−38.6%Reduced
Emerald Mutual Fund Advisers Trust621,317$10.3M0.36%−31,539−4.8%Reduced
Emerald Advisers, LLC565,728$9.39M0.34%−3,335−0.6%Reduced
Artal Group S.A.400,000$6.64M0.16%00.0%Unchanged
Geode Capital Management, LLC316,094$5.25M0.00%+25,174+8.7%Added
State Street Corp313,951$5.21M0.00%+29,382+10.3%Added
Northern Trust Corp178,200$2.96M0.00%−11,804−6.2%Reduced
Voya Investment Management LLC113,146$1.88M0.00%−9,408−7.7%Reduced
Nuveen Asset Management, LLC74,466$1.24M0.00%−16,993−18.6%Reduced
First Manhattan Co73,783$1.22M0.00%00.0%Unchanged
Bank of New York Mellon Corp67,463$1.12M0.00%+8,955+15.3%Added
Goldman Sachs Group Inc62,090$1.03M0.00%+2,545+4.3%Added
Russell Investments Group, Ltd.54,381$901.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP51,978$863.0K0.00%−21,182−29.0%Reduced
Dimensional Fund Advisors LP50,184$832.0K0.00%+34,521+220.4%Added
Charles Schwab Investment Management Inc43,336$720.0K0.00%−317−0.7%Reduced
ACT Capital Management, LLC37,500$623.0K0.32%00.0%Unchanged
Swiss National Bank37,300$619.0K0.00%00.0%Unchanged
Two Sigma Investments, LP29,134$484.0K0.00%+18,643+177.7%Added
Simplex Trading, LLC20,344$438.0K0.02%+200+1.0%Added
California State Teachers Retirement System23,636$392.0K0.00%−783−3.2%Reduced
Deutsche Bank AG23,635$392.0K0.00%+12,475+111.8%Added
UBS Asset Management Americas Inc22,695$376.7K0.00%00.0%Unchanged
UBS Group AG21,210$352.0K0.00%−1,075−4.8%Reduced
State of Wisconsin Investment Board18,900$314.0K0.00%00.0%Unchanged
Rhumbline Advisers18,436$306.0K0.00%+825+4.7%Added
Barclays PLC17,916$298.0K0.00%+15,586+668.9%Added
Morgan Stanley14,597$242.0K0.00%+516+3.7%Added
Bank of America Corp14,543$242.0K0.00%+1,666+12.9%Added
Alliancebernstein L.P.13,400$222.0K0.00%00.0%Unchanged
New York State Common Retirement Fund12,394$206.0K0.00%−4,130−25.0%Reduced
Millennium Management LLC11,933$198.0K0.00%+11,933New
Manufacturers Life Insurance Company, The10,923$181.0K0.00%−267−2.4%Reduced
Squarepoint Ops LLC10,700$178.0K0.00%+10,700New
Two Sigma Advisers, LP10,400$173.0K0.00%+10,400New
American International Group, Inc.9,694$161.0K0.00%−231−2.3%Reduced
SG Americas Securities, LLC9,202$153.0K0.00%+9,202New
Virtus ETF Advisers LLC8,790$146.0K0.06%−457−4.9%Reduced
JPMorgan Chase & Co8,771$146.0K0.00%+685+8.5%Added
MetLife Investment Management7,129$118.3K0.00%00.0%Unchanged
Legal & General Group Plc5,618$93.0K0.00%+3,255+137.7%Added
Metropolitan Life Insurance Co5,405$89.7K0.00%00.0%Unchanged
Group One Trading, L.P.4,423$73.0K0.00%+538+13.8%Added
Cubist Systematic Strategies, LLC4,019$67.0K0.00%+4,019New
Citigroup Inc3,682$61.0K0.00%+585+18.9%Added
BNP Paribas Arbitrage, SA3,135$52.0K0.00%+2,367+308.2%Added
Ancora Advisors, LLC2,500$41.0K0.00%00.0%Unchanged
Royal Bank of Canada2,151$36.0K0.00%+938+77.3%Added
Ameritas Investment Partners, Inc.1,179$20.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,112$18.0K0.00%−345−23.7%Reduced
Great West Life Assurance Co997$17.0K0.00%00.0%Unchanged
Point72 Hong Kong Ltd605$10.0K0.00%+605New
Penserra Capital Management LLC595$9.00K0.00%00.0%Unchanged
Quantbot Technologies LP500$8.00K0.00%00.0%Unchanged
Macquarie Group Ltd393$7.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.100$2.00K0.00%00.0%Unchanged
US Bancorp103$2.00K0.00%+103New
Federation des caisses Desjardins du Quebec84$1.39K0.00%00.0%Unchanged
Daiwa Securities Group Inc.42$1.00K0.00%00.0%Unchanged
Parallel Advisors, LLC90$1.00K0.00%+90New
Wells Fargo & Company2$00.00%00.0%Unchanged
Bamco Inc0$00.00%−237,800−100.0%Sold out
Stifel Financial Corp0$00.00%−132,596−100.0%Sold out
DSAM Partners (London) Ltd0$00.00%−67,125−100.0%Sold out
Citadel Advisors LLC0$00.00%−13,119−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−7,000−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−2,000−100.0%Sold out
Ellevest, Inc.0$00.00%−48−100.0%Sold out