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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q4 2022

Institutional positions in Applied Therapeutics, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
38
−6 vs. Q3 2022
Shares held
19.7M
−2.99M (−13.2%) vs. Q3 2022
Total value
$15.1M
−$6.02M (−28.6%) vs. Q3 2022
New holders
5
6 more added
Sold out
11
18 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 38 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2022: $15.1M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q3 2022.

Institutions holding APLT in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Franklin Resources Inc4,775,484$3.63M0.00%00.0%Unchanged
OrbiMed Advisors LLC3,050,921$2.32M0.04%−1,199,079−28.2%Reduced
FMR LLC2,972,371$2.26M0.00%−231,600−7.2%Reduced
Knoll Capital Management, LLC2,450,000$1.86M4.20%+1,367,877+126.4%Added
Alyeska Investment Group, L.P.1,268,052$963.7K0.01%−1,945,161−60.5%Reduced
Vanguard Group Inc796,562$605.4K0.00%+343,299+75.7%Added
Point72 Asset Management, L.P.719,938$547.2K0.00%−1,000,000−58.1%Reduced
Rock Springs Capital Management LP596,680$453.5K0.01%−105,000−15.0%Reduced
Bank of Montreal323,100$355.4K0.00%+323,100New
Artal Group S.A.400,000$304.0K0.02%00.0%Unchanged
Geode Capital Management, LLC361,078$274.0K0.00%+29,012+8.7%Added
Laurion Capital Management LP345,900$262.9K0.01%00.0%Unchanged
Renaissance Technologies LLC317,978$242.0K0.00%−16,311−4.9%Reduced
BlackRock Inc.293,781$223.3K0.00%−234,265−44.4%Reduced
Two Sigma Advisers, LP249,900$189.9K0.00%+700+0.3%Added
Two Sigma Investments, LP177,773$135.1K0.00%−3,828−2.1%Reduced
Pura Vida Investments, LLC101,654$77.3K0.01%+101,654New
State Street Corp94,415$71.8K0.00%00.0%Unchanged
Acadian Asset Management LLC87,395$65.0K0.00%00.0%Unchanged
Millennium Management LLC61,943$47.0K0.00%−37,538−37.7%Reduced
Bridgeway Capital Management, LLC58,800$44.7K0.00%−50,000−46.0%Reduced
Northern Trust Corp50,960$38.7K0.00%00.0%Unchanged
Ergoteles LLC36,524$27.8K0.00%−15,161−29.3%Reduced
Susquehanna International Group, LLP21,931$16.7K0.00%−809−3.6%Reduced
Jane Street Group, LLC17,707$13.5K0.00%+17,707New
Perennial Investment Advisors, LLC11,600$8.82K0.00%00.0%Unchanged
UBS Group AG11,368$8.64K0.00%−15,781−58.1%Reduced
Two Sigma Securities, LLC10,933$8.31K0.00%+10,933New
Tower Research Capital LLC (TRC)5,078$4.00K0.00%−5,368−51.4%Reduced
Morgan Stanley4,480$3.41K0.00%−15,597−77.7%Reduced
BNP Paribas Arbitrage, SA3,121$2.37K0.00%+2,481+387.7%Added
Group One Trading, L.P.1,086$8250.00%00.0%Unchanged
Citadel Advisors LLC374$2840.00%+374New
Citigroup Inc293$2230.00%−101,652−99.7%Reduced
Wells Fargo & Company268$2040.00%+7+2.7%Added
Bank of America Corp129$980.00%−329−71.8%Reduced
Federation des caisses Desjardins du Quebec84$640.00%00.0%Unchanged
JPMorgan Chase & Co388$00.00%−1,646−80.9%Reduced
First Manhattan Co0$00.00%−73,783−100.0%Sold out
Maven Securities LTD0$00.00%−50,000−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−28,321−100.0%Sold out
HRT Financial LP0$00.00%−28,380−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−15,060−100.0%Sold out
Man Group plc0$00.00%−11,287−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−4,038−100.0%Sold out
Royal Bank of Canada0$00.00%−58−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−42−100.0%Sold out
Allworth Financial LP0$00.00%−250−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−450−100.0%Sold out