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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q4 2021

Institutional positions in Applied Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
−1 vs. Q3 2021
Shares held
14.9M
−186.5K (−1.2%) vs. Q3 2021
Total value
$133.6M
−$117.4M (−46.8%) vs. Q3 2021
New holders
10
29 more added
Sold out
11
16 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 69 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2021: $133.6M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q3 2021.

Institutions holding APLT in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC2,313,681$20.7M0.27%+56,294+2.5%Added
FMR LLC2,243,476$20.1M0.00%−166,771−6.9%Reduced
BlackRock Inc.1,298,531$11.6M0.00%+5,714+0.4%Added
Franklin Resources Inc1,125,294$10.1M0.00%+291,012+34.9%Added
Point72 Asset Management, L.P.1,114,000$9.97M0.04%+98,729+9.7%Added
Knoll Capital Management, LLC1,032,123$9.24M5.08%00.0%Unchanged
Vanguard Group Inc851,138$7.62M0.00%+839+0.1%Added
Rock Springs Capital Management LP701,680$6.28M0.15%00.0%Unchanged
Emerald Mutual Fund Advisers Trust631,922$5.66M0.20%+10,605+1.7%Added
Emerald Advisers, LLC611,525$5.47M0.20%+45,797+8.1%Added
Driehaus Capital Management LLC517,107$4.63M0.05%−122,450−19.1%Reduced
Artal Group S.A.400,000$3.58M0.11%00.0%Unchanged
State Street Corp341,651$3.06M0.00%+27,700+8.8%Added
Geode Capital Management, LLC303,243$2.71M0.00%−12,851−4.1%Reduced
Northern Trust Corp177,681$1.59M0.00%−519−0.3%Reduced
Kore Private Wealth LLC125,000$1.12M0.14%+125,000New
Russell Investments Group, Ltd.75,800$677.0K0.00%+21,419+39.4%Added
Goldman Sachs Group Inc75,505$676.0K0.00%+13,415+21.6%Added
UBS Group AG74,421$666.0K0.00%+53,211+250.9%Added
First Manhattan Co73,783$660.0K0.00%00.0%Unchanged
Dimensional Fund Advisors LP72,925$653.0K0.00%+22,741+45.3%Added
Millennium Management LLC70,361$630.0K0.00%+58,428+489.6%Added
Bank of New York Mellon Corp68,396$612.0K0.00%+933+1.4%Added
Nuveen Asset Management, LLC62,007$555.0K0.00%−12,459−16.7%Reduced
Susquehanna International Group, LLP60,463$541.0K0.00%+8,485+16.3%Added
Charles Schwab Investment Management Inc45,079$404.0K0.00%+1,743+4.0%Added
Swiss National Bank37,300$334.0K0.00%00.0%Unchanged
Bank of America Corp36,031$322.0K0.00%+21,488+147.8%Added
Two Sigma Investments, LP28,431$254.0K0.00%−703−2.4%Reduced
California State Teachers Retirement System24,025$215.0K0.00%+389+1.6%Added
UBS Asset Management Americas Inc22,695$203.1K0.00%00.0%Unchanged
Barclays PLC21,498$193.0K0.00%+3,582+20.0%Added
ACT Capital Management, LLC20,000$179.0K0.13%−17,500−46.7%Reduced
State of Wisconsin Investment Board18,900$169.0K0.00%00.0%Unchanged
Morgan Stanley18,809$168.0K0.00%+4,212+28.9%Added
Rhumbline Advisers18,115$162.0K0.00%−321−1.7%Reduced
Renaissance Technologies LLC17,600$158.0K0.00%+17,600New
Two Sigma Advisers, LP12,900$115.0K0.00%+2,500+24.0%Added
Alliancebernstein L.P.12,500$112.0K0.00%−900−6.7%Reduced
New York State Common Retirement Fund12,340$110.0K0.00%−54−0.4%Reduced
Ensign Peak Advisors, Inc11,940$107.0K0.00%+11,940New
Deutsche Bank AG11,405$102.0K0.00%−12,230−51.7%Reduced
Manufacturers Life Insurance Company, The11,189$100.0K0.00%+266+2.4%Added
Walleye Capital LLC11,200$100.0K0.00%+11,200New
Trexquant Investment LP11,091$99.0K0.01%+11,091New
Citadel Advisors LLC10,658$95.0K0.00%+10,658New
Credit Suisse AG10,355$93.0K0.00%+10,355New
American International Group, Inc.9,413$84.0K0.00%−281−2.9%Reduced
JPMorgan Chase & Co9,258$83.0K0.00%+487+5.6%Added
Wells Fargo & Company7,720$69.0K0.00%+7,718+385,900.0%Added
Cubist Systematic Strategies, LLC7,426$66.0K0.00%+3,407+84.8%Added
Legal & General Group Plc5,618$50.0K0.00%00.0%Unchanged
Citigroup Inc5,503$49.0K0.00%+1,821+49.5%Added
Simplex Trading, LLC5,428$48.0K0.00%−14,916−73.3%Reduced
BNP Paribas Arbitrage, SA4,850$43.4K0.00%+1,715+54.7%Added
Royal Bank of Canada4,377$39.0K0.00%+2,226+103.5%Added
Tower Research Capital LLC (TRC)4,269$38.0K0.00%+3,157+283.9%Added
Group One Trading, L.P.3,529$32.0K0.00%−894−20.2%Reduced
Denali Advisors LLC2,800$25.0K0.01%+2,800New
Ancora Advisors, LLC2,500$22.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,179$11.0K0.00%00.0%Unchanged
Great West Life Assurance Co997$9.00K0.00%00.0%Unchanged
Aquatic Capital Management LLC800$7.00K0.01%+800New
Point72 Hong Kong Ltd550$5.00K0.00%−55−9.1%Reduced
Macquarie Group Ltd393$4.00K0.00%00.0%Unchanged
Quadrant Capital Group LLC113$1.00K0.00%+113New
Federation des caisses Desjardins du Quebec84$7520.00%00.0%Unchanged
Advisor Group Holdings, Inc.50$00.00%−50−50.0%Reduced
Daiwa Securities Group Inc.42$00.00%00.0%Unchanged
Alkeon Capital Management LLC0$00.00%−639,458−100.0%Sold out
Voya Investment Management LLC0$00.00%−113,146−100.0%Sold out
Squarepoint Ops LLC0$00.00%−10,700−100.0%Sold out
SG Americas Securities, LLC0$00.00%−9,202−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−8,790−100.0%Sold out
MetLife Investment Management0$00.00%−7,129−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−5,405−100.0%Sold out
Penserra Capital Management LLC0$00.00%−595−100.0%Sold out
Quantbot Technologies LP0$00.00%−500−100.0%Sold out
US Bancorp0$00.00%−103−100.0%Sold out
Parallel Advisors, LLC0$00.00%−90−100.0%Sold out