Applied Therapeutics, Inc.
APLTDelisted Feb 3, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001697532
Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.
13F holders, Q4 2025
Institutional positions in Applied Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 52
- −16 vs. Q3 2025
- Shares held
- 58.9M
- −35.8M (−37.8%) vs. Q3 2025
- Total value
- $5.93M
- −$51.2M (−89.6%) vs. Q3 2025
- New holders
- 9
- 13 more added
- Sold out
- 25
- 19 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 0 | $0 |
| Q4 2025 | 52 | $5.93M |
| Q3 2025 | 70 | $57.2M |
| Q2 2025 | 75 | $27.4M |
| Q1 2025 | 90 | $51.8M |
| Q4 2024 | 119 | $98.5M |
| Q3 2024 | 126 | $960.9M |
| Q2 2024 | 94 | $481.8M |
| Q1 2024 | 89 | $638.6M |
| Q4 2023 | 83 | $205.8M |
| Q3 2023 | 55 | $107.0M |
| Q2 2023 | 40 | $40.3M |
| Q1 2023 | 36 | $15.6M |
| Q4 2022 | 38 | $15.1M |
| Q3 2022 | 44 | $21.1M |
| Q2 2022 | 53 | $25.3M |
| Q1 2022 | 71 | $26.0M |
| Q4 2021 | 69 | $133.6M |
| Q3 2021 | 70 | $250.9M |
| Q2 2021 | 69 | $319.3M |
| Q1 2021 | 67 | $278.6M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| T. Rowe Price Investment Management, Inc. | 21,747,844 | $2.17M | 0.00% | +344,544+1.6% | Added |
| Vanguard Group Inc | 6,353,018 | $635.3K | 0.00% | +1,250,329+24.5% | Added |
| Knoll Capital Management, LLC | 6,050,000 | $605.0K | 0.28% | −1,749,687−22.4% | Reduced |
| Deltec Asset Management LLC | 3,847,449 | $384.7K | 0.06% | +3,847,449 | New |
| BlackRock, Inc. | 3,251,462 | $325.1K | 0.00% | −592,271−15.4% | Reduced |
| Pathstone Holdings, LLC | 2,643,540 | $305.1K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 2,706,156 | $270.6K | 0.00% | +2,706,156 | New |
| Jane Street Group, LLC | 2,087,404 | $208.7K | 0.00% | +2,087,404 | New |
| Geode Capital Management, LLC | 1,492,903 | $149.3K | 0.00% | +214,747+16.8% | Added |
| Adage Capital Partners GP, L.L.C. | 1,211,629 | $121.2K | 0.00% | −1,000,000−45.2% | Reduced |
| Millennium Management LLC | 1,051,846 | $105.2K | 0.00% | −855,368−44.8% | Reduced |
| UBS Group AG | 718,924 | $71.9K | 0.00% | −1,186,701−62.3% | Reduced |
| Deutsche Bank AG | 622,226 | $62.2K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 572,759 | $57.3K | 0.00% | +572,759 | New |
| State Street Corp | 558,178 | $55.8K | 0.00% | +39,660+7.6% | Added |
| Virtu Financial LLC | 496,288 | $50.0K | 0.00% | +445,271+872.8% | Added |
| Lynx1 Capital Management LP | 410,500 | $41.0K | 0.01% | +410,500 | New |
| Marshall Wace, LLP | 337,389 | $33.7K | 0.00% | −2,205,299−86.7% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 327,137 | $32.7K | 0.00% | +44,289+15.7% | Added |
| Equitec Proprietary Markets, LLC | 300,600 | $30.1K | 0.14% | +300,600 | New |
| Bank of New York Mellon Corp | 253,575 | $25.4K | 0.00% | +174,157+219.3% | Added |
| Northern Trust Corp | 245,144 | $24.5K | 0.00% | +71,429+41.1% | Added |
| Rockefeller Capital Management L.P. | 241,897 | $24.2K | 0.00% | −150,000−38.3% | Reduced |
| GTS Securities LLC | 200,009 | $20.0K | 0.00% | +200,009 | New |
| Morgan Stanley | 178,474 | $17.8K | 0.00% | −534,841−75.0% | Reduced |
| Change Path, LLC | 169,974 | $17.0K | 0.00% | +69,962+70.0% | Added |
| Citigroup Inc | 163,449 | $16.3K | 0.00% | +156,608+2,289.3% | Added |
| Goldman Sachs Group Inc | 146,219 | $14.6K | 0.00% | −8,922−5.8% | Reduced |
| Roble, Belko & Company, Inc | 65,571 | $7.00K | 0.00% | +34,730+112.6% | Added |
| Tudor Investment Corp Et Al | 57,454 | $5.75K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 52,692 | $5.27K | 0.00% | −424,465−89.0% | Reduced |
| Sphera Funds Management Ltd. | 50,000 | $5.00K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 48,675 | $4.87K | 0.00% | −26,586−35.3% | Reduced |
| SG Americas Securities, LLC | 41,748 | $4.00K | 0.00% | +25,344+154.5% | Added |
| Adams Wealth Management | 38,637 | $3.86K | 0.00% | 00.0% | Unchanged |
| CacheTech Inc. | 38,637 | $3.86K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 19,675 | $1.97K | 0.00% | −14,680−42.7% | Reduced |
| Cresset Asset Management, LLC | 17,091 | $1.71K | 0.00% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 17,020 | $1.70K | 0.00% | +17,020 | New |
| AQR Capital Management LLC | 13,413 | $1.34K | 0.00% | −96,274−87.8% | Reduced |
| JPMorgan Chase & Co | 12,064 | $1.21K | 0.00% | +4,433+58.1% | Added |
| Perennial Investment Advisors, LLC | 11,600 | $1.16K | 0.00% | 00.0% | Unchanged |
| Quest Partners LLC | 4,661 | $466 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 3,109 | $311 | 0.00% | −8,561−73.4% | Reduced |
| BNP Paribas Arbitrage, SA | 2,974 | $297 | 0.00% | −501−14.4% | Reduced |
| SBI Securities Co., Ltd. | 788 | $79 | 0.00% | −35−4.3% | Reduced |
| Rhumbline Advisers | 544 | $54 | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 427 | $43 | 0.00% | +427 | New |
| FMR LLC | 184 | $18 | 0.00% | −17,298−98.9% | Reduced |
| Federation des caisses Desjardins du Quebec | 84 | $8 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 852 | $0 | 0.00% | −201,960−99.6% | Reduced |
| Barclays PLC | 1 | $0 | 0.00% | −5,264−100.0% | Reduced |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −14,250,000−100.0% | Sold out |
| Propel Bio Management, LLC | 0 | $0 | 0.00% | −11,285,420−100.0% | Sold out |
| Simplify Asset Management Inc. | 0 | $0 | 0.00% | −4,487,505−100.0% | Sold out |
| The PNC Financial Services Group, Inc. | 0 | $0 | 0.00% | −2,901,184−100.0% | Sold out |
| Rock Springs Capital Management LP | 0 | $0 | 0.00% | −2,075,991−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −2,003,338−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −1,167,269−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −673,764−100.0% | Sold out |
| Birchview Capital, LP | 0 | $0 | 0.00% | −225,000−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −198,933−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −158,865−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −105,110−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −94,870−100.0% | Sold out |
| Ethic Inc. | 0 | $0 | 0.00% | −27,193−100.0% | Sold out |
| China Universal Asset Management Co., Ltd. | 0 | $0 | 0.00% | −25,243−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −23,579−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −16,803−100.0% | Sold out |
| JustInvest LLC | 0 | $0 | 0.00% | −16,244−100.0% | Sold out |
| Stratos Wealth Advisors, LLC | 0 | $0 | 0.00% | −10,500−100.0% | Sold out |
| Beaumont Capital Management, LLC | 0 | $0 | 0.00% | −10,403−100.0% | Sold out |
| Mirae Asset Global Investments Co., Ltd. | 0 | $0 | 0.00% | −5,568−100.0% | Sold out |
| Capital Advisors, Ltd. LLC | 0 | $0 | 0.00% | −2,367−100.0% | Sold out |
| Sunbelt Securities, Inc. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Parallel Advisors, LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| CWM, LLC | 0 | $0 | 0.00% | −376−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | – | – | – | – | Not filed |
| Wolverine Trading, LLC | – | – | – | – | Not filed |