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Applied Therapeutics, Inc.

APLTDelisted Feb 3, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001697532

Applied Therapeutics, Inc. was delisted on Feb 3, 2026; its insiders filed their last Form 4 on Feb 4, 2026; 52 institutions reported holding it in 13F filings for Q4 2025, worth $5.93M in total; no superinvestor held it.

13F holders, Q2 2022

Institutional positions in Applied Therapeutics, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
53
−16 vs. Q1 2022
Shares held
26.7M
+14.4M (+117.0%) vs. Q1 2022
Total value
$25.3M
−$657.5K (−2.5%) vs. Q1 2022
New holders
10
14 more added
Sold out
26
20 more reduced

2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLT on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 53 institutions
Q1 2021: 67 institutionsQ2 2021: 69 institutionsQ3 2021: 70 institutionsQ4 2021: 69 institutionsQ1 2022: 71 institutionsQ2 2022: 53 institutionsQ3 2022: 44 institutionsQ4 2022: 38 institutionsQ1 2023: 36 institutionsQ2 2023: 40 institutionsQ3 2023: 55 institutionsQ4 2023: 83 institutionsQ1 2024: 89 institutionsQ2 2024: 94 institutionsQ3 2024: 126 institutionsQ4 2024: 119 institutionsQ1 2025: 90 institutionsQ2 2025: 75 institutionsQ3 2025: 70 institutionsQ4 2025: 52 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2022: $25.3M
Q1 2021: $278.6MQ2 2021: $319.3MQ3 2021: $250.9MQ4 2021: $133.6MQ1 2022: $26.0MQ2 2022: $25.3MQ3 2022: $21.1MQ4 2022: $15.1MQ1 2023: $15.6MQ2 2023: $40.3MQ3 2023: $107.0MQ4 2023: $205.8MQ1 2024: $638.6MQ2 2024: $481.8MQ3 2024: $960.9MQ4 2024: $98.5MQ1 2025: $51.8MQ2 2025: $27.4MQ3 2025: $57.2MQ4 2025: $5.93MQ1 2026: $0Q2 2026: $0
Institutions holding APLT and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 202552$5.93M
Q3 202570$57.2M
Q2 202575$27.4M
Q1 202590$51.8M
Q4 2024119$98.5M
Q3 2024126$960.9M
Q2 202494$481.8M
Q1 202489$638.6M
Q4 202383$205.8M
Q3 202355$107.0M
Q2 202340$40.3M
Q1 202336$15.6M
Q4 202238$15.1M
Q3 202244$21.1M
Q2 202253$25.3M
Q1 202271$26.0M
Q4 202169$133.6M
Q3 202170$250.9M
Q2 202169$319.3M
Q1 202167$278.6M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Applied Therapeutics, Inc.; share changes are against Q1 2022.

Institutions holding APLT in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Franklin Resources Inc4,775,484$4.53M0.00%+3,179,934+199.3%Added
Alyeska Investment Group, L.P.4,357,690$4.13M0.05%+4,357,690New
OrbiMed Advisors LLC4,250,000$4.03M0.08%+4,250,000New
FMR LLC4,007,283$3.80M0.00%+3,103,990+343.6%Added
Point72 Asset Management, L.P.2,835,000$2.69M0.01%+286,000+11.2%Added
Knoll Capital Management, LLC1,082,123$1.03M0.59%00.0%Unchanged
Rock Springs Capital Management LP701,680$665.0K0.02%00.0%Unchanged
Empery Asset Management, LP675,000$640.0K3.47%+675,000New
Vanguard Group Inc514,219$488.0K0.00%−96,648−15.8%Reduced
BlackRock Inc.488,938$463.0K0.00%−874,465−64.1%Reduced
Artal Group S.A.400,000$379.0K0.02%00.0%Unchanged
Millennium Management LLC360,814$342.0K0.00%+252,718+233.8%Added
Laurion Capital Management LP345,900$328.0K0.01%+345,900New
Renaissance Technologies LLC264,178$250.0K0.00%−18,022−6.4%Reduced
Two Sigma Investments, LP178,251$169.0K0.00%−102,022−36.4%Reduced
Geode Capital Management, LLC162,443$154.0K0.00%−125,487−43.6%Reduced
HRT Financial LP144,286$136.0K0.00%+95,549+196.1%Added
Kore Private Wealth LLC125,000$119.0K0.02%00.0%Unchanged
Two Sigma Advisers, LP112,400$107.0K0.00%+7,300+6.9%Added
Morgan Stanley109,596$103.0K0.00%+89,170+436.6%Added
State Street Corp94,415$90.0K0.00%−331,989−77.9%Reduced
Ergoteles LLC86,600$82.0K0.00%+86,600New
Citadel Advisors LLC78,843$75.0K0.00%+62,158+372.5%Added
First Manhattan Co73,783$69.0K0.00%00.0%Unchanged
D. E. Shaw & Co., Inc.71,098$67.0K0.00%−75,325−51.4%Reduced
Bridgeway Capital Management, LLC58,800$56.0K0.00%−50,000−46.0%Reduced
Maven Securities LTD50,000$47.0K0.01%+50,000New
Acadian Asset Management LLC46,832$45.0K0.00%+13,487+40.4%Added
Dimensional Fund Advisors LP36,961$35.0K0.00%−2,349−6.0%Reduced
Algert Global LLC37,160$35.0K0.00%+8,740+30.8%Added
Northern Trust Corp35,591$34.0K0.00%−128,792−78.3%Reduced
UBS Group AG25,863$24.0K0.00%+3,850+17.5%Added
BNP Paribas Arbitrage, SA22,954$21.8K0.00%+21,415+1,391.5%Added
Qube Research & Technologies Ltd17,370$16.0K0.00%+17,370New
Goldman Sachs Group Inc16,134$15.0K0.00%−78,530−83.0%Reduced
AQR Capital Management LLC13,907$13.0K0.00%−71,157−83.7%Reduced
Susquehanna International Group, LLP13,076$12.0K0.00%+13,076New
Tower Research Capital LLC (TRC)10,661$10.0K0.00%+4,799+81.9%Added
Citigroup Inc9,077$9.00K0.00%+6,276+224.1%Added
Simplex Trading, LLC7,105$6.00K0.00%−929−11.6%Reduced
Bank of America Corp4,392$4.00K0.00%−15,796−78.2%Reduced
Cubist Systematic Strategies, LLC4,038$4.00K0.00%00.0%Unchanged
Ancora Advisors, LLC2,500$2.00K0.00%00.0%Unchanged
JPMorgan Chase & Co1,222$1.00K0.00%−10,328−89.4%Reduced
Group One Trading, L.P.1,086$1.00K0.00%−100−8.4%Reduced
Federation des caisses Desjardins du Quebec84$800.00%00.0%Unchanged
New York State Common Retirement Fund140$00.00%−12,200−98.9%Reduced
Credit Suisse AG9$00.00%−11,175−99.9%Reduced
Barclays PLC1$00.00%−3,987−100.0%Reduced
Wells Fargo & Company119$00.00%−1,346−91.9%Reduced
Daiwa Securities Group Inc.42$00.00%00.0%Unchanged
Allworth Financial LP250$00.00%+250New
Mirae Asset Global Investments Co., Ltd.30,669––+30,669New
Bank of New York Mellon Corp0$00.00%−70,458−100.0%Sold out
Walleye Capital LLC0$00.00%−52,273−100.0%Sold out
Nuveen Asset Management, LLC0$00.00%−53,840−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−38,968−100.0%Sold out
Swiss National Bank0$00.00%−37,300−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−34,372−100.0%Sold out
Deutsche Bank AG0$00.00%−31,910−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−30,500−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−25,015−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−22,695−100.0%Sold out
California State Teachers Retirement System0$00.00%−22,271−100.0%Sold out
ACT Capital Management, LLC0$00.00%−20,000−100.0%Sold out
JustInvest LLC0$00.00%−20,119−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−18,900−100.0%Sold out
Rhumbline Advisers0$00.00%−17,409−100.0%Sold out
Alliancebernstein L.P.0$00.00%−12,500−100.0%Sold out
American International Group, Inc.0$00.00%−8,793−100.0%Sold out
Legal & General Group Plc0$00.00%−5,618−100.0%Sold out
Amalgamated Bank0$00.00%−2,828−100.0%Sold out
Royal Bank of Canada0$00.00%−1,089−100.0%Sold out
Great West Life Assurance Co0$00.00%−997−100.0%Sold out
Ameritas Investment Partners, Inc.0$00.00%−1,179−100.0%Sold out
Federated Hermes, Inc.0$00.00%−519−100.0%Sold out
Macquarie Group Ltd0$00.00%−393−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−550−100.0%Sold out
Cutler Group LP0$00.00%−220−100.0%Sold out
Parametric Portfolio Associates LLC––––Not filed
Amalgamated Financial Corp.––––Not filed