Anaptysbio, Inc
ANAB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001370053
No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Anaptysbio, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 179
- +13 vs. Q3 2025
- Shares held
- 29.4M
- −2.32M (−7.3%) vs. Q3 2025
- Total value
- $1.42B
- +$442.7M (+45.2%) vs. Q3 2025
- New holders
- 37
- 51 more added
- Sold out
- 24
- 64 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 213 | $2.03B |
| Q1 2026 | 208 | $1.55B |
| Q4 2025 | 179 | $1.42B |
| Q3 2025 | 166 | $980.2M |
| Q2 2025 | 148 | $816.2M |
| Q1 2025 | 153 | $742.8M |
| Q4 2024 | 136 | $468.9M |
| Q3 2024 | 160 | $1.13B |
| Q2 2024 | 135 | $746.6M |
| Q1 2024 | 133 | $658.1M |
| Q4 2023 | 119 | $646.4M |
| Q3 2023 | 116 | $544.5M |
| Q2 2023 | 116 | $614.9M |
| Q1 2023 | 113 | $675.4M |
| Q4 2022 | 118 | $1.02B |
| Q3 2022 | 114 | $830.6M |
| Q2 2022 | 124 | $632.6M |
| Q1 2022 | 131 | $735.4M |
| Q4 2021 | 136 | $964.4M |
| Q3 2021 | 127 | $748.8M |
| Q2 2021 | 122 | $720.6M |
| Q1 2021 | 122 | $628.6M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 7,880,094 | $382.0M | 17.51% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 1,932,890 | $93.7M | 0.15% | −332,638−14.7% | Reduced |
| BlackRock, Inc. | 1,734,430 | $84.1M | 0.00% | +12,106+0.7% | Added |
| Vanguard Group Inc | 1,544,037 | $74.9M | 0.00% | +67,048+4.5% | Added |
| Tang Capital Management LLC | 1,332,087 | $64.6M | 3.19% | −1,552−0.1% | Reduced |
| State Street Corp | 1,053,474 | $51.1M | 0.00% | +180,042+20.6% | Added |
| Morgan Stanley | 1,034,562 | $50.2M | 0.00% | −521,696−33.5% | Reduced |
| Sanofi | 821,917 | $39.8M | 12.84% | 00.0% | Unchanged |
| Millennium Management LLC | 813,571 | $39.4M | 0.03% | −705,659−46.4% | Reduced |
| Palo Alto Investors LP | 690,032 | $33.5M | 4.66% | +16,512+2.5% | Added |
| D. E. Shaw & Co., Inc. | 670,288 | $32.5M | 0.02% | +320,928+91.9% | Added |
| 683 Capital Management, LLC | 648,093 | $31.4M | 2.61% | +101,093+18.5% | Added |
| First Light Asset Management, LLC | 646,238 | $31.3M | 2.40% | −343,923−34.7% | Reduced |
| Arrowstreet Capital, Limited Partnership | 559,744 | $27.1M | 0.02% | +189,286+51.1% | Added |
| Woodline Partners LP | 501,023 | $24.3M | 0.09% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 469,494 | $22.8M | 0.00% | −4,132−0.9% | Reduced |
| Affinity Asset Advisors, LLC | 444,692 | $21.6M | 1.55% | +444,692 | New |
| Goldman Sachs Group Inc | 398,914 | $19.3M | 0.00% | +69,094+20.9% | Added |
| Two Sigma Advisers, LP | 356,700 | $17.3M | 0.03% | −17,000−4.5% | Reduced |
| Nuveen, LLC | 316,685 | $15.4M | 0.00% | −22,586−6.7% | Reduced |
| Federated Hermes, Inc. | 299,416 | $14.5M | 0.02% | +106,089+54.9% | Added |
| Sofinnova Investments, Inc. | 287,690 | $13.9M | 0.60% | +33,422+13.1% | Added |
| Two Sigma Investments, LP | 256,635 | $12.4M | 0.02% | +215+0.1% | Added |
| Voloridge Investment Management, LLC | 229,137 | $11.1M | 0.04% | +219,816+2,358.3% | Added |
| Ensign Peak Advisors, Inc | 215,454 | $10.4M | 0.02% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 198,660 | $9.63M | 0.00% | −7,781−3.8% | Reduced |
| Northern Trust Corp | 181,884 | $8.82M | 0.00% | −13,679−7.0% | Reduced |
| BNP Paribas Arbitrage, SA | 164,823 | $7.99M | 0.01% | +59,160+56.0% | Added |
| Squarepoint Ops LLC | 160,731 | $7.79M | 0.02% | +92,717+136.3% | Added |
| Soleus Capital Management, L.P. | 135,000 | $6.54M | 0.28% | −491,040−78.4% | Reduced |
| Bank of America Corp | 130,767 | $6.34M | 0.00% | +3,526+2.8% | Added |
| Granahan Investment Management Inc | 125,855 | $6.10M | 0.26% | −21,918−14.8% | Reduced |
| Invesco Ltd. | 124,006 | $6.01M | 0.00% | +81,625+192.6% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 122,476 | $5.94M | 0.02% | +122,476 | New |
| Eversept Partners, LP | 120,927 | $5.86M | 0.33% | +120,927 | New |
| Jump Financial, LLC | 120,217 | $5.83M | 0.07% | +38,140+46.5% | Added |
| Victory Capital Management Inc | 110,583 | $5.36M | 0.00% | −93,472−45.8% | Reduced |
| Citadel Advisors LLC | 109,483 | $5.31M | 0.00% | +83,003+313.5% | Added |
| Qube Research & Technologies Ltd | 108,965 | $5.28M | 0.01% | +108,965 | New |
| HighMark Wealth Management LLC | 94,050 | $4.56M | 1.86% | −41,000−30.4% | Reduced |
| Nomura Asset Management International Inc. | 93,732 | $4.54M | 0.01% | +93,732 | New |
| Jane Street Group, LLC | 84,447 | $4.09M | 0.00% | −96,665−53.4% | Reduced |
| ExodusPoint Capital Management, LP | 83,313 | $4.04M | 0.04% | +56,813+214.4% | Added |
| Renaissance Technologies LLC | 76,300 | $3.70M | 0.01% | −47,000−38.1% | Reduced |
| Citigroup Inc | 73,453 | $3.56M | 0.00% | +2,919+4.1% | Added |
| HRT Financial LP | 70,130 | $3.40M | 0.01% | +45,105+180.2% | Added |
| UBS Group AG | 70,032 | $3.40M | 0.00% | −5,230−6.9% | Reduced |
| Wellington Management Group LLP | 61,187 | $2.97M | 0.00% | −5,544−8.3% | Reduced |
| Barclays PLC | 59,654 | $2.89M | 0.00% | −3,798−6.0% | Reduced |
| Trexquant Investment LP | 58,809 | $2.85M | 0.03% | −52,969−47.4% | Reduced |
| Fisher Asset Management, LLC | 56,564 | $2.74M | 0.00% | −2,314−3.9% | Reduced |
| Penserra Capital Management LLC | 56,352 | $2.73M | 0.03% | +56,352 | New |
| Bank of New York Mellon Corp | 55,345 | $2.68M | 0.00% | −1,685−3.0% | Reduced |
| Jacobs Levy Equity Management, Inc | 55,088 | $2.67M | 0.01% | −323,364−85.4% | Reduced |
| Moody Aldrich Partners LLC | 47,601 | $2.31M | 0.43% | −2,281−4.6% | Reduced |
| Bleakley Financial Group, LLC | 43,547 | $2.11M | 0.04% | +3,566+8.9% | Added |
| PDT Partners, LLC | 43,001 | $2.08M | 0.14% | 00.0% | Unchanged |
| Credit Agricole S A | 40,000 | $1.94M | 0.01% | +40,000 | New |
| XTX Topco Ltd | 38,637 | $1.87M | 0.05% | +20,526+113.3% | Added |
| Susquehanna Portfolio Strategies, LLC | 35,948 | $1.74M | 0.03% | +500+1.4% | Added |
| Rafferty Asset Management, LLC | 35,310 | $1.71M | 0.01% | +5,225+17.4% | Added |
| DCF Advisers, LLC | 35,250 | $1.71M | 0.56% | −12,750−26.6% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 33,101 | $1.60M | 0.04% | +33,101 | New |
| Alliancebernstein L.P. | 30,520 | $1.48M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 30,508 | $1.48M | 0.00% | −2,763−8.3% | Reduced |
| Advisor Group Holdings, Inc. | 27,737 | $1.34M | 0.00% | +25,921+1,427.4% | Added |
| Swiss National Bank | 27,600 | $1.34M | 0.00% | −800−2.8% | Reduced |
| FMR LLC | 27,108 | $1.31M | 0.00% | −26,054−49.0% | Reduced |
| AQR Capital Management LLC | 26,309 | $1.28M | 0.00% | +135+0.5% | Added |
| Price T Rowe Associates Inc | 26,005 | $1.26M | 0.00% | −273,306−91.3% | Reduced |
| Campbell & CO Investment Adviser LLC | 25,368 | $1.23M | 0.06% | +7,087+38.8% | Added |
| Headlands Technologies LLC | 25,278 | $1.23M | 0.10% | +25,278 | New |
| Rhumbline Advisers | 25,032 | $1.21M | 0.00% | −4,212−14.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 24,431 | $1.18M | 0.01% | +24,431 | New |
| Quadrature Capital Ltd | 24,280 | $1.18M | 0.01% | +24,280 | New |
| Mackenzie Financial Corp | 24,228 | $1.17M | 0.00% | +24,228 | New |
| NEOS Investment Management LLC | 22,895 | $1.11M | 0.01% | +11,920+108.6% | Added |
| Tema ETFs LLC | 22,560 | $1.09M | 0.08% | +11,585+105.6% | Added |
| Wells Fargo & Company | 22,207 | $1.08M | 0.00% | +8,464+61.6% | Added |
| Panagora Asset Management Inc | 20,872 | $1.01M | 0.00% | −42,985−67.3% | Reduced |
| Russell Investments Group, Ltd. | 19,714 | $955.8K | 0.00% | −14,318−42.1% | Reduced |
| Legal & General Group Plc | 18,180 | $881.4K | 0.00% | −1,324−6.8% | Reduced |
| Tudor Investment Corp Et Al | 17,305 | $838.9K | 0.00% | +3,436+24.8% | Added |
| Algert Global LLC | 16,400 | $795.1K | 0.01% | −67,367−80.4% | Reduced |
| Creative Planning | 15,254 | $739.5K | 0.00% | −1,453−8.7% | Reduced |
| Cresset Asset Management, LLC | 15,121 | $733.1K | 0.00% | −632−4.0% | Reduced |
| Brinker Capital Investments, LLC | 14,697 | $712.5K | 0.01% | +958+7.0% | Added |
| Deutsche Bank AG | 14,381 | $697.2K | 0.00% | +1,700+13.4% | Added |
| California State Teachers Retirement System | 14,138 | $685.4K | 0.00% | −77−0.5% | Reduced |
| Profund Advisors LLC | 13,088 | $634.5K | 0.02% | +6,525+99.4% | Added |
| Voya Investment Management LLC | 12,760 | $618.6K | 0.00% | −201−1.6% | Reduced |
| Los Angeles Capital Management LLC | 15,101 | $550.7K | 0.00% | +225+1.5% | Added |
| JPMorgan Chase & Co | 10,916 | $529.2K | 0.00% | −3,936−26.5% | Reduced |
| Engineers Gate Manager LP | 10,880 | $527.5K | 0.01% | −18,257−62.7% | Reduced |
| Gsa Capital Partners LLP | 10,695 | $518.0K | 0.04% | −26,579−71.3% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 10,641 | $515.4K | 0.00% | −26−0.2% | Reduced |
| SG Americas Securities, LLC | 10,428 | $506.0K | 0.00% | +10,428 | New |
| MetLife Investment Management | 10,327 | $500.7K | 0.00% | −1,601−13.4% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,286 | $450.2K | 0.00% | +2,788+42.9% | Added |
| New York State Common Retirement Fund | 9,088 | $440.6K | 0.00% | −1,498−14.2% | Reduced |