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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

In the last 90 days, Anaptysbio, Inc insiders filed 0 open-market purchases and 1 sale; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Anaptysbio, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
179
+13 vs. Q3 2025
Shares held
29.4M
−2.32M (−7.3%) vs. Q3 2025
Total value
$1.42B
+$442.7M (+45.2%) vs. Q3 2025
New holders
37
51 more added
Sold out
24
64 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 179 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ4 2025: $1.42B
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q3 2025.

Institutions holding ANAB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
State of Wisconsin Investment Board8,955$434.1K0.00%+8,955New
Bridgefront Capital, LLC8,549$414.5K0.10%+8,549New
Entropy Technologies, LP8,300$402.4K0.02%+8,300New
Blueshift Asset Management, LLC7,852$380.7K0.11%+7,852New
Quest Partners LLC7,761$376.3K0.02%−1,282−14.2%Reduced
China Universal Asset Management Co., Ltd.7,512$364.2K0.03%−2,395−24.2%Reduced
Janus Henderson Group PLC7,464$362.2K0.00%00.0%Unchanged
Glenmede Trust Co NA7,346$356.1K0.00%+7,346New
Intech Investment Management LLC6,922$335.6K0.00%−883−11.3%Reduced
SummitTX Capital, L.P.6,528$316.5K0.01%+6,528New
Duncan Williams Asset Management, LLC6,525$315.7K0.08%+6,525New
Quantinno Capital Management LP6,434$311.9K0.00%+6,434New
Savant Capital, LLC6,295$305.2K0.00%+6,295New
Envestnet Asset Management Inc6,097$295.6K0.00%+6,097New
Virtus Investment Advisers, Inc.5,919$287.0K0.08%+1,059+21.8%Added
Virginia Retirement Systems Et Al5,850$283.6K0.00%+5,850New
Acadian Asset Management LLC5,809$280.0K0.00%+5,809New
Manufacturers Life Insurance Company, The5,682$275.5K0.00%−1,037−15.4%Reduced
Ascent Group, LLC5,662$274.5K0.01%+5,662New
Police & Firemen's Retirement System of New Jersey5,641$273.5K0.00%+1,082+23.7%Added
FMB Wealth Management5,592$271.1K0.11%+5,592New
State Board of Administration of Florida Retirement System5,526$267.9K0.00%+5,526New
SEI Investments Co4,966$240.8K0.00%−9,955−66.7%Reduced
Public Employees Retirement Association of Colorado4,864$236.0K0.00%00.0%Unchanged
ProShare Advisors LLC4,598$222.9K0.00%+4,598New
nVerses Capital, LLC4,438$215.2K0.48%+4,438New
Latash Investments, LLC4,393$213.0K0.14%+4,393New
Aquatic Capital Management LLC3,174$153.9K0.00%−28,124−89.9%Reduced
KLP Kapitalforvaltning AS3,000$145.4K0.00%00.0%Unchanged
SBI Securities Co., Ltd.1,834$88.9K0.00%+1,830+45,750.0%Added
Royal Bank of Canada1,718$83.0K0.00%+1,560+987.3%Added
Ameritas Investment Partners, Inc.1,647$79.8K0.00%−270−14.1%Reduced
US Bancorp1,642$79.6K0.00%−148−8.3%Reduced
Larson Financial Group LLC1,624$78.7K0.00%+284+21.2%Added
Caitong International Asset Management Co., Ltd1,530$74.2K0.02%+1,383+940.8%Added
Bessemer Group Inc1,461$71.0K0.00%+33+2.3%Added
Mirae Asset Global Investments Co., Ltd.1,345$65.2K0.00%+263+24.3%Added
CWM, LLC1,011$49.0K0.00%+2+0.2%Added
Nisa Investment Advisors, LLC963$46.7K0.00%−87−8.3%Reduced
EverSource Wealth Advisors, LLC875$42.4K0.00%−90−9.3%Reduced
Smartleaf Asset Management LLC835$40.3K0.00%+821+5,864.3%Added
Great West Life Assurance Co750$36.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)727$35.2K0.00%−1,213−62.5%Reduced
Amalgamated Bank580$28.0K0.00%−165−22.1%Reduced
GF Fund Management Co. Ltd.543$26.3K0.00%−59−9.8%Reduced
Versant Capital Management, Inc454$22.0K0.00%00.0%Unchanged
GAMMA Investing LLC384$18.6K0.00%+35+10.0%Added
Farther Finance Advisors, LLC384$18.6K0.00%+109+39.6%Added
Signaturefd, LLC352$17.1K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.334$16.2K0.00%+334New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.238$12.0K0.00%−34−12.5%Reduced
Whittier Trust Co224$9.84K0.00%−9−3.9%Reduced
Quadrant Capital Group LLC175$8.48K0.00%00.0%Unchanged
Rothschild Investment LLC165$8.00K0.00%00.0%Unchanged
Allworth Financial LP143$6.93K0.00%−528−78.7%Reduced
Basecamp Wealth Advisors LLC142$6.88K0.00%+142New
Aster Capital Management (DIFC) Ltd125$6.06K0.00%+125New
Sterling Capital Management LLC116$5.62K0.00%+69+146.8%Added
The PNC Financial Services Group, Inc.104$5.04K0.00%−6−5.5%Reduced
UMA Financial Services, Inc.85$4.12K0.00%00.0%Unchanged
Daiwa Securities Group Inc.75$4.00K0.00%−30−28.6%Reduced
Rockefeller Capital Management L.P.65$3.15K0.00%+65New
Parallel Advisors, LLC55$2.67K0.00%00.0%Unchanged
Optiver Holding B.V.54$2.62K0.00%−36−40.0%Reduced
Steward Partners Investment Advisory, LLC43$2.08K0.00%00.0%Unchanged
Assetmark, Inc36$1.75K0.00%00.0%Unchanged
Essential Partners LLC33$1.60K0.00%00.0%Unchanged
Parkside Financial Bank & Trust25$1.21K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.19$9210.00%00.0%Unchanged
Stone House Investment Management, LLC13$6300.00%+8+160.0%Added
Massmutual Trust Co FSB12$5820.00%00.0%Unchanged
MAI Capital Management10$4850.00%+10New
SRS Capital Advisors, Inc.8$3880.00%+8New
True Wealth Design, LLC4$1940.00%00.0%Unchanged
Sunbelt Securities, Inc.4$1940.00%00.0%Unchanged
TFC Financial Management1$490.00%00.0%Unchanged
CIBC Private Wealth Group, LLC1$480.00%00.0%Unchanged
IFP Advisors, Inc1$480.00%00.0%Unchanged
Covestor Ltd5$00.00%−6,577−99.9%Reduced
Assenagon Asset Management S.A.0$00.00%−839,934−100.0%Sold out
Franklin Resources Inc0$00.00%−47,332−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−194,485−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−145,191−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−144,604−100.0%Sold out
Macquarie Group Ltd0$00.00%−93,732−100.0%Sold out
Walleye Capital LLC0$00.00%−56,422−100.0%Sold out
Marshall Wace, LLP0$00.00%−54,416−100.0%Sold out
Ikarian Capital, LLC0$00.00%−48,410−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−27,402−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−25,299−100.0%Sold out
Virtu Financial LLC0$00.00%−15,531−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−15,320−100.0%Sold out
Alps Advisors Inc0$00.00%−13,335−100.0%Sold out
Man Group plc0$00.00%−12,859−100.0%Sold out
DRW Securities, LLC0$00.00%−6,629−100.0%Sold out
Diadema Partners LP0$00.00%−3,295−100.0%Sold out
Global Retirement Partners, LLC0$00.00%−1,230−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−754−100.0%Sold out
Clear Street Markets LLC0$00.00%−170−100.0%Sold out
Principal Securities, Inc.0$00.00%−14−100.0%Sold out