Anaptysbio, Inc
ANAB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001370053
No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Anaptysbio, Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 208
- +31 vs. Q4 2025
- Shares held
- 28.3M
- +441.4K (+1.6%) vs. Q4 2025
- Total value
- $1.55B
- +$203.4M (+15.1%) vs. Q4 2025
- New holders
- 51
- 59 more added
- Sold out
- 20
- 70 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 213 | $2.03B |
| Q1 2026 | 208 | $1.55B |
| Q4 2025 | 179 | $1.42B |
| Q3 2025 | 166 | $980.2M |
| Q2 2025 | 148 | $816.2M |
| Q1 2025 | 153 | $742.8M |
| Q4 2024 | 136 | $468.9M |
| Q3 2024 | 160 | $1.13B |
| Q2 2024 | 135 | $746.6M |
| Q1 2024 | 133 | $658.1M |
| Q4 2023 | 119 | $646.4M |
| Q3 2023 | 116 | $544.5M |
| Q2 2023 | 116 | $614.9M |
| Q1 2023 | 113 | $675.4M |
| Q4 2022 | 118 | $1.02B |
| Q3 2022 | 114 | $830.6M |
| Q2 2022 | 124 | $632.6M |
| Q1 2022 | 131 | $735.4M |
| Q4 2021 | 136 | $964.4M |
| Q3 2021 | 127 | $748.8M |
| Q2 2021 | 122 | $720.6M |
| Q1 2021 | 122 | $628.6M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 7,880,094 | $437.0M | 18.68% | 00.0% | Unchanged |
| BlackRock, Inc. | 1,681,380 | $93.2M | 0.00% | −53,050−3.1% | Reduced |
| Tang Capital Management LLC | 1,330,879 | $73.8M | 3.75% | −1,208−0.1% | Reduced |
| Morgan Stanley | 993,905 | $55.1M | 0.00% | −40,657−3.9% | Reduced |
| State Street Corp | 992,445 | $55.0M | 0.00% | −61,029−5.8% | Reduced |
| Affinity Asset Advisors, LLC | 940,000 | $52.1M | 3.06% | +495,308+111.4% | Added |
| Vanguard Capital Management LLC | 853,151 | $47.3M | 0.00% | +853,151 | New |
| Palo Alto Investors LP | 638,161 | $35.4M | 5.41% | −51,871−7.5% | Reduced |
| 683 Capital Management, LLC | 625,000 | $34.7M | 3.22% | −23,093−3.6% | Reduced |
| D. E. Shaw & Co., Inc. | 579,296 | $32.1M | 0.03% | −90,992−13.6% | Reduced |
| First Light Asset Management, LLC | 565,431 | $31.4M | 2.81% | −80,807−12.5% | Reduced |
| Sanofi | 821,917 | $30.4M | 9.04% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 520,241 | $28.9M | 0.00% | +50,747+10.8% | Added |
| Vanguard Portfolio Management LLC | 519,870 | $28.8M | 0.00% | +519,870 | New |
| Bank of America Corp | 501,086 | $27.8M | 0.00% | +370,319+283.2% | Added |
| Arrowstreet Capital, Limited Partnership | 492,120 | $27.3M | 0.01% | −67,624−12.1% | Reduced |
| Millennium Management LLC | 475,572 | $26.4M | 0.02% | −337,999−41.5% | Reduced |
| FMR LLC | 472,704 | $26.2M | 0.00% | +445,596+1,643.8% | Added |
| Two Sigma Investments, LP | 465,083 | $25.8M | 0.02% | +208,448+81.2% | Added |
| Federated Hermes, Inc. | 364,121 | $20.2M | 0.03% | +64,705+21.6% | Added |
| Woodline Partners LP | 344,256 | $19.1M | 0.07% | −156,767−31.3% | Reduced |
| Goldman Sachs Group Inc | 332,743 | $18.5M | 0.00% | −66,171−16.6% | Reduced |
| Synergy Financial Management, LLC | 317,106 | $17.6M | 1.87% | +317,106 | New |
| Nuveen, LLC | 316,065 | $17.5M | 0.00% | −620−0.2% | Reduced |
| Squarepoint Ops LLC | 267,703 | $14.8M | 0.03% | +106,972+66.6% | Added |
| Qube Research & Technologies Ltd | 254,736 | $14.1M | 0.02% | +145,771+133.8% | Added |
| Sofinnova Investments, Inc. | 248,253 | $13.8M | 0.69% | −39,437−13.7% | Reduced |
| Apis Capital Advisors, LLC | 238,000 | $13.2M | 2.04% | +238,000 | New |
| Citadel Advisors LLC | 233,450 | $12.9M | 0.01% | +123,967+113.2% | Added |
| Charles Schwab Investment Management Inc | 192,687 | $10.7M | 0.00% | −5,973−3.0% | Reduced |
| Northern Trust Corp | 183,519 | $10.2M | 0.00% | +1,635+0.9% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 158,562 | $8.79M | 0.02% | +36,086+29.5% | Added |
| Vanguard Fiduciary Trust Co | 135,082 | $7.49M | 0.00% | +135,082 | New |
| HSBC Holdings PLC | 125,717 | $7.14M | 0.00% | +125,717 | New |
| Ensign Peak Advisors, Inc | 125,633 | $6.97M | 0.01% | −89,821−41.7% | Reduced |
| Invesco Ltd. | 121,103 | $6.72M | 0.00% | −2,903−2.3% | Reduced |
| Victory Capital Management Inc | 108,203 | $6.00M | 0.00% | −2,380−2.2% | Reduced |
| BNP Paribas Arbitrage, SA | 96,971 | $5.38M | 0.00% | −67,852−41.2% | Reduced |
| HighMark Wealth Management LLC | 94,050 | $5.22M | 2.12% | 00.0% | Unchanged |
| Nomura Asset Management International Inc. | 93,732 | $5.20M | 0.01% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 90,900 | $5.04M | 0.01% | +14,600+19.1% | Added |
| Jane Street Group, LLC | 86,038 | $4.77M | 0.01% | +1,591+1.9% | Added |
| Trexquant Investment LP | 85,167 | $4.72M | 0.03% | +26,358+44.8% | Added |
| UBS Group AG | 79,670 | $4.42M | 0.00% | +9,638+13.8% | Added |
| Voloridge Investment Management, LLC | 78,952 | $4.38M | 0.02% | −150,185−65.5% | Reduced |
| Citigroup Inc | 73,406 | $4.07M | 0.00% | −47−0.1% | Reduced |
| Marshall Wace, LLP | 68,047 | $3.77M | 0.00% | +68,047 | New |
| Granahan Investment Management Inc | 66,182 | $3.67M | 0.18% | −59,673−47.4% | Reduced |
| Franklin Resources Inc | 65,820 | $3.65M | 0.00% | +65,820 | New |
| Prudential Financial Inc | 64,050 | $3.55M | 0.00% | +64,050 | New |
| Fisher Asset Management, LLC | 56,596 | $3.14M | 0.00% | +32+0.1% | Added |
| Point72 Asset Management, L.P. | 55,303 | $3.07M | 0.01% | −1,877,587−97.1% | Reduced |
| Deutsche Bank AG | 52,038 | $2.89M | 0.00% | +37,657+261.9% | Added |
| Bank of New York Mellon Corp | 51,115 | $2.83M | 0.00% | −4,230−7.6% | Reduced |
| XTX Topco Ltd | 50,537 | $2.80M | 0.05% | +11,900+30.8% | Added |
| Wellington Management Group LLP | 46,881 | $2.60M | 0.00% | −14,306−23.4% | Reduced |
| Penserra Capital Management LLC | 43,430 | $2.41M | 0.03% | −12,922−22.9% | Reduced |
| Bleakley Financial Group, LLC | 43,120 | $2.39M | 0.04% | −427−1.0% | Reduced |
| HRT Financial LP | 40,504 | $2.25M | 0.01% | −29,626−42.2% | Reduced |
| Moody Aldrich Partners LLC | 39,455 | $2.19M | 0.39% | −8,146−17.1% | Reduced |
| Toroso Investments, LLC | 36,352 | $2.02M | 0.01% | +36,352 | New |
| Susquehanna Portfolio Strategies, LLC | 35,948 | $1.99M | 0.03% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 33,720 | $1.87M | 0.00% | +9,492+39.2% | Added |
| Virtu Financial LLC | 33,323 | $1.85M | 0.08% | +33,323 | New |
| Wells Fargo & Company | 33,180 | $1.84M | 0.00% | +10,973+49.4% | Added |
| AQR Capital Management LLC | 32,467 | $1.80M | 0.00% | +6,158+23.4% | Added |
| Tema ETFs LLC | 31,069 | $1.72M | 0.12% | +8,509+37.7% | Added |
| UBS Asset Management Americas Inc | 30,727 | $1.70M | 0.00% | +219+0.7% | Added |
| Price T Rowe Associates Inc | 29,691 | $1.65M | 0.00% | +3,686+14.2% | Added |
| Jacobs Levy Equity Management, Inc | 28,625 | $1.59M | 0.01% | −26,463−48.0% | Reduced |
| Martingale Asset Management L P | 28,142 | $1.56M | 0.04% | +28,142 | New |
| Engineers Gate Manager LP | 27,815 | $1.54M | 0.02% | +16,935+155.7% | Added |
| State of Wisconsin Investment Board | 27,619 | $1.53M | 0.00% | +18,664+208.4% | Added |
| Swiss National Bank | 27,600 | $1.53M | 0.00% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 31,320 | $1.52M | 0.00% | +800+2.6% | Added |
| Rafferty Asset Management, LLC | 27,249 | $1.51M | 0.01% | −8,061−22.8% | Reduced |
| Eversept Partners, LP | 27,089 | $1.50M | 0.10% | −93,838−77.6% | Reduced |
| Susquehanna International Group, LLP | 26,577 | $1.47M | 0.00% | +26,577 | New |
| SG Americas Securities, LLC | 24,851 | $1.38M | 0.00% | +14,423+138.3% | Added |
| Headlands Technologies LLC | 24,558 | $1.36M | 0.16% | −720−2.8% | Reduced |
| Rhumbline Advisers | 23,848 | $1.32M | 0.00% | −1,184−4.7% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 22,701 | $1.26M | 0.02% | −10,400−31.4% | Reduced |
| J. Goldman & Co LP | 21,205 | $1.18M | 0.05% | +21,205 | New |
| Hussman Strategic Advisors, Inc. | 21,000 | $1.16M | 0.25% | +21,000 | New |
| Credit Agricole S A | 20,000 | $1.11M | 0.00% | −20,000−50.0% | Reduced |
| DCF Advisers, LLC | 18,775 | $1.04M | 0.39% | −16,475−46.7% | Reduced |
| Walleye Capital LLC | 18,425 | $1.02M | 0.01% | +18,425 | New |
| PDT Partners, LLC | 17,595 | $975.8K | 0.06% | −25,406−59.1% | Reduced |
| Creative Planning | 16,836 | $933.7K | 0.00% | +1,582+10.4% | Added |
| Virginia Retirement Systems Et Al | 16,050 | $890.1K | 0.01% | +10,200+174.4% | Added |
| Los Angeles Capital Management LLC | 15,664 | $868.7K | 0.00% | +563+3.7% | Added |
| Canada Pension Plan Investment Board | 14,900 | $826.4K | 0.00% | +14,900 | New |
| Twinbeech Capital LP | 14,518 | $805.2K | 0.08% | +14,518 | New |
| Voya Investment Management LLC | 14,346 | $795.6K | 0.00% | +1,586+12.4% | Added |
| California State Teachers Retirement System | 14,000 | $776.4K | 0.00% | −138−1.0% | Reduced |
| Gotham Asset Management, LLC | 13,972 | $774.9K | 0.00% | +13,972 | New |
| Cresset Asset Management, LLC | 13,868 | $769.1K | 0.00% | −1,253−8.3% | Reduced |
| Legal & General Group Plc | 13,831 | $767.1K | 0.00% | −4,349−23.9% | Reduced |
| Brookwood Investment Group LLC | 13,362 | $741.1K | 0.09% | +13,362 | New |
| Russell Investments Group, Ltd. | 13,288 | $737.0K | 0.00% | −6,426−32.6% | Reduced |