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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Anaptysbio, Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
148
−3 vs. Q1 2025
Shares held
36.8M
−3.18M (−8.0%) vs. Q1 2025
Total value
$816.2M
+$73.6M (+9.9%) vs. Q1 2025
New holders
28
45 more added
Sold out
31
55 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 148 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ2 2025: $816.2M
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q1 2025.

Institutions holding ANAB in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC7,880,094$174.9M10.38%00.0%Unchanged
First Light Asset Management, LLC3,539,593$78.6M10.19%−1,094,009−23.6%Reduced
Point72 Asset Management, L.P.2,474,874$54.9M0.13%+106,504+4.5%Added
Morgan Stanley1,869,840$41.5M0.00%+1,365,204+270.5%Added
BlackRock, Inc.1,786,934$39.7M0.00%−389,664−17.9%Reduced
Vanguard Group Inc1,537,550$34.1M0.00%+20,225+1.3%Added
Tang Capital Management LLC1,330,879$29.5M1.49%−214,274−13.9%Reduced
UBS Group AG1,272,499$28.2M0.01%+782,226+159.5%Added
Bank of America Corp1,076,799$23.9M0.00%−67,160−5.9%Reduced
Citigroup Inc1,046,488$23.2M0.02%−24,759−2.3%Reduced
Sofinnova Investments, Inc.1,032,362$22.9M1.56%−127,671−11.0%Reduced
Sanofi821,917$18.2M10.38%00.0%Unchanged
State Street Corp821,031$18.2M0.00%−39,692−4.6%Reduced
Palo Alto Investors LP812,821$18.0M3.84%−207,892−20.4%Reduced
Price T Rowe Associates Inc673,171$14.9M0.00%−241,910−26.4%Reduced
Victory Capital Management Inc532,085$11.8M0.01%+125,655+30.9%Added
Woodline Partners LP501,023$11.1M0.06%−290,000−36.7%Reduced
683 Capital Management, LLC500,000$11.1M1.13%+304,373+155.6%Added
Geode Capital Management, LLC463,358$10.3M0.00%−27,809−5.7%Reduced
Jacobs Levy Equity Management, Inc368,447$8.18M0.03%+351,960+2,134.8%Added
Franklin Resources Inc354,508$7.87M0.00%+1170.0%Added
Nuveen, LLC323,534$7.18M0.00%+267,522+477.6%Added
Soleus Capital Management, L.P.321,040$7.13M0.49%+218,988+214.6%Added
Two Sigma Advisers, LP290,400$6.45M0.01%+22,300+8.3%Added
Goldman Sachs Group Inc279,835$6.21M0.00%−742−0.3%Reduced
Renaissance Technologies LLC263,086$5.84M0.01%−75,614−22.3%Reduced
JPMorgan Chase & Co247,625$5.50M0.00%+233,325+1,631.6%Added
Two Sigma Investments, LP231,369$5.14M0.01%−34,489−13.0%Reduced
Ensign Peak Advisors, Inc215,454$4.78M0.01%00.0%Unchanged
Millennium Management LLC203,542$4.52M0.00%+185,735+1,043.0%Added
Trexquant Investment LP199,242$4.42M0.05%+45,679+29.7%Added
Northern Trust Corp196,263$4.36M0.00%−16,623−7.8%Reduced
Susquehanna International Group, LLP189,327$4.20M0.01%+144,990+327.0%Added
Charles Schwab Investment Management Inc157,135$3.49M0.00%+3,779+2.5%Added
Arrowstreet Capital, Limited Partnership150,810$3.35M0.00%+150,810New
HighMark Wealth Management LLC145,550$3.23M1.58%+53,550+58.2%Added
Granahan Investment Management Inc131,655$2.92M0.12%−14,836−10.1%Reduced
Camber Capital Management LP125,000$2.77M0.39%−625,000−83.3%Reduced
Citadel Advisors LLC118,286$2.63M0.00%−254,283−68.3%Reduced
D. E. Shaw & Co., Inc.112,349$2.49M0.00%−17,305−13.3%Reduced
Squarepoint Ops LLC109,388$2.43M0.01%+109,388New
Barclays PLC99,999$2.22M0.00%+43,780+77.9%Added
Macquarie Group Ltd93,732$2.08M0.00%00.0%Unchanged
Balyasny Asset Management LLC92,852$2.06M0.00%+60,778+189.5%Added
Sectoral Asset Management Inc83,900$1.86M1.23%+83,900New
Invesco Ltd.83,174$1.85M0.00%+61,838+289.8%Added
Wellington Management Group LLP80,213$1.78M0.00%+4,192+5.5%Added
Voya Investment Management LLC73,005$1.62M0.00%−23,967−24.7%Reduced
FMR LLC72,119$1.60M0.00%−1,833,035−96.2%Reduced
Gsa Capital Partners LLP69,799$1.55M0.11%+69,799New
Aquatic Capital Management LLC65,810$1.46M0.03%+65,810New
Moody Aldrich Partners LLC60,094$1.33M0.26%−23,130−27.8%Reduced
Bank of New York Mellon Corp59,225$1.31M0.00%−1,982−3.2%Reduced
Fisher Asset Management, LLC58,899$1.31M0.00%+210.0%Added
UBS Asset Management Americas Inc49,805$1.11M0.00%+14,892+42.7%Added
DCF Advisers, LLC48,000$1.07M0.51%+13,150+37.7%Added
Jane Street Group, LLC44,668$991.6K0.00%+44,668New
PDT Partners, LLC44,465$987.1K0.06%−64−0.1%Reduced
UBS Oconnor LLC38,528$855.3K0.02%−8,523−18.1%Reduced
Bleakley Financial Group, LLC37,551$833.6K0.02%+37,551New
FMB Wealth Management35,592$790.1K0.38%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)33,523$744.2K0.00%00.0%Unchanged
SummitTX Capital, L.P.33,434$742.2K0.03%−23,675−41.5%Reduced
Panagora Asset Management Inc33,369$740.8K0.00%+33,369New
Wells Fargo & Company33,328$739.9K0.00%+21,951+192.9%Added
Susquehanna Portfolio Strategies, LLC32,803$728.2K0.02%+32,803New
Rhumbline Advisers30,705$681.6K0.00%−198−0.6%Reduced
XTX Topco Ltd30,642$680.3K0.03%+30,642New
Alliancebernstein L.P.30,520$677.5K0.00%00.0%Unchanged
AQR Capital Management LLC27,722$615.4K0.00%−2,289−7.6%Reduced
Rafferty Asset Management, LLC26,829$595.6K0.00%−4,351−14.0%Reduced
Swiss National Bank26,400$586.1K0.00%−6,000−18.5%Reduced
Engineers Gate Manager LP24,745$549.3K0.01%+24,745New
Russell Investments Group, Ltd.23,791$528.2K0.00%+23,791New
ExodusPoint Capital Management, LP23,756$527.0K0.01%+1,812+8.3%Added
Brevan Howard Capital Management LP22,953$509.6K0.01%+8,761+61.7%Added
Legal & General Group Plc19,504$433.0K0.00%−859−4.2%Reduced
Assenagon Asset Management S.A.16,959$376.5K0.00%−225,526−93.0%Reduced
Creative Planning16,854$374.2K0.00%+3,571+26.9%Added
Alps Advisors Inc15,863$352.2K0.00%−7,263−31.4%Reduced
Ikarian Capital, LLC15,662$347.7K0.12%+15,662New
Nebula Research & Development LLC15,533$344.8K0.03%+28+0.2%Added
Allianz Asset Management GmbH15,200$337.4K0.00%+15,200New
Los Angeles Capital Management LLC15,027$333.6K0.00%+15,027New
Exome Asset Management LLC15,000$333.0K0.27%−101,623−87.1%Reduced
California State Teachers Retirement System14,217$315.6K0.00%−373−2.6%Reduced
Cresset Asset Management, LLC13,033$289.3K0.00%−1,580−10.8%Reduced
Deutsche Bank AG12,681$281.5K0.00%−3,115−19.7%Reduced
Corton Capital Inc.12,004$266.5K0.31%+1,305+12.2%Added
NEOS Investment Management LLC11,404$253.2K0.00%+11,404New
Tema ETFs LLC11,404$253.2K0.07%+11,404New
Intech Investment Management LLC10,795$239.6K0.00%+10,795New
Tudor Investment Corp Et Al9,419$209.1K0.00%−775−7.6%Reduced
Federated Hermes, Inc.8,274$183.7K0.00%00.0%Unchanged
New York State Common Retirement Fund7,924$175.9K0.00%00.0%Unchanged
Glenmede Investment Management, LP7,546$167.5K0.00%+7,546New
Zurcher Kantonalbank (Zurich Cantonalbank)6,498$144.3K0.00%+4,436+215.1%Added
China Universal Asset Management Co., Ltd.5,901$131.0K0.01%−250−4.1%Reduced
US Bancorp5,898$130.9K0.00%+4,145+236.5%Added
SG Americas Securities, LLC4,921$109.0K0.00%−7,213−59.4%Reduced