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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.05B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Anaptysbio, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
213
+8 vs. Q1 2026
Shares held
30.1M
+1.89M (+6.7%) vs. Q1 2026
Total value
$2.05B
+$499.1M (+32.2%) vs. Q1 2026
New holders
45
73 more added
Sold out
37
65 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 213 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ2 2026: $2.05B
Q1 2021: $628.6MQ2 2021: $721.7MQ3 2021: $748.8MQ4 2021: $966.1MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $681.7MQ2 2023: $614.9MQ3 2023: $546.3MQ4 2023: $659.7MQ1 2024: $687.0MQ2 2024: $746.9MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $744.6MQ2 2025: $816.2MQ3 2025: $980.6MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.05B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.05B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.6M
Q2 2025148$816.2M
Q1 2025153$744.6M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.9M
Q1 2024133$687.0M
Q4 2023119$659.7M
Q3 2023116$546.3M
Q2 2023116$614.9M
Q1 2023113$681.7M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$966.1M
Q3 2021127$748.8M
Q2 2021122$721.7M
Q1 2021122$628.6M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q1 2026.

Institutions holding ANAB in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC7,880,094$531.9M26.37%00.0%Unchanged
BlackRock, Inc.1,844,049$124.5M0.00%+162,669+9.7%Added
Tang Capital Management LLC1,330,879$89.8M4.08%00.0%Unchanged
State Street Corp1,286,194$86.8M0.00%+293,749+29.6%Added
Vanguard Capital Management LLC906,233$61.2M0.00%+53,082+6.2%Added
Affinity Asset Advisors, LLC826,109$55.8M2.73%−113,891−12.1%Reduced
Sanofi821,917$55.5M10.39%00.0%Unchanged
Millennium Management LLC807,316$54.5M0.04%+331,744+69.8%Added
Woodline Partners LP717,014$48.4M0.15%+372,758+108.3%Added
683 Capital Management, LLC660,000$44.6M4.10%+35,000+5.6%Added
Geode Capital Management, LLC637,873$43.1M0.00%+117,632+22.6%Added
Palo Alto Investors LP603,489$40.7M5.63%−34,672−5.4%Reduced
Goldman Sachs Group Inc584,070$39.4M0.00%+251,327+75.5%Added
First Light Asset Management, LLC582,004$39.3M2.39%+16,573+2.9%Added
D. E. Shaw & Co., Inc.539,666$36.4M0.02%−39,630−6.8%Reduced
Vanguard Portfolio Management LLC527,858$35.6M0.00%+7,988+1.5%Added
Apis Capital Advisors, LLC497,000$33.5M3.27%+259,000+108.8%Added
Sofinnova Investments, Inc.493,536$33.3M1.78%+245,283+98.8%Added
Arrowstreet Capital, Limited Partnership488,651$33.0M0.01%−3,469−0.7%Reduced
Nuveen, LLC420,664$28.4M0.01%+104,599+33.1%Added
Bank of America Corp417,812$28.2M0.00%−83,274−16.6%Reduced
Citadel Advisors LLC394,373$26.6M0.02%+160,923+68.9%Added
Federated Hermes, Inc.391,667$26.4M0.04%+27,546+7.6%Added
Squarepoint Ops LLC324,446$21.9M0.04%+56,743+21.2%Added
Two Sigma Investments, LP262,995$17.8M0.01%−202,088−43.5%Reduced
First Trust Advisors LP258,989$17.5M0.01%+258,989New
Morgan Stanley257,091$17.4M0.00%−736,814−74.1%Reduced
Coppell Advisory Solutions LLC3,638$16.6M1.37%+3,638New
FMR LLC240,511$16.2M0.00%−232,193−49.1%Reduced
Qube Research & Technologies Ltd228,777$15.4M0.02%−25,959−10.2%Reduced
HSBC Holdings PLC216,949$14.9M0.01%+91,232+72.6%Added
Empowered Funds, LLC206,010$13.9M0.07%+206,010New
Northern Trust Corp202,767$13.7M0.00%+19,248+10.5%Added
Charles Schwab Investment Management Inc202,305$13.7M0.00%+9,618+5.0%Added
Invesco Ltd.202,056$13.6M0.00%+80,953+66.8%Added
Dimensional Fund Advisors LP185,444$12.5M0.00%+185,444New
Greenhaven Road Investment Management, L.P.171,059$11.5M7.50%+171,059New
Victory Capital Management Inc169,227$11.4M0.01%+61,024+56.4%Added
Mackenzie Financial Corp150,979$10.2M0.01%+117,259+347.7%Added
UBS Group AG146,832$9.91M0.00%+67,162+84.3%Added
Vanguard Fiduciary Trust Co146,724$9.90M0.00%+11,642+8.6%Added
Connor, Clark & Lunn Investment Management Ltd.141,026$9.52M0.02%−17,536−11.1%Reduced
Ensign Peak Advisors, Inc107,096$7.23M0.01%−18,537−14.8%Reduced
Franklin Resources Inc106,949$7.22M0.00%+41,129+62.5%Added
Citigroup Inc99,114$6.69M0.00%+25,708+35.0%Added
Nomura Asset Management International Inc.93,732$6.33M0.01%00.0%Unchanged
Prudential Financial Inc85,932$5.80M0.01%+21,882+34.2%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main83,942$5.67M0.00%+83,942New
JPMorgan Chase & Co80,236$5.29M0.00%+68,591+589.0%Added
Granahan Investment Management Inc75,962$5.13M0.18%+9,780+14.8%Added
Irenic Capital Management LP70,447$4.76M0.34%+70,447New
Eversept Partners, LP69,983$4.72M0.26%+42,894+158.3%Added
SG Americas Securities, LLC66,730$4.50M0.00%+41,879+168.5%Added
Jacobs Levy Equity Management, Inc62,336$4.21M0.02%+33,711+117.8%Added
State of Wisconsin Investment Board61,753$4.17M0.01%+34,134+123.6%Added
Renaissance Technologies LLC58,300$3.94M0.01%−32,600−35.9%Reduced
Voloridge Investment Management, LLC57,555$3.88M0.02%−21,397−27.1%Reduced
Bank of New York Mellon Corp56,401$3.81M0.00%+5,286+10.3%Added
Deutsche Bank AG46,884$3.16M0.00%−5,154−9.9%Reduced
AQR Capital Management LLC46,323$3.13M0.00%+13,856+42.7%Added
Marshall Wace, LLP43,822$2.96M0.00%−24,225−35.6%Reduced
Bleakley Financial Group, LLC42,761$2.89M0.04%−359−0.8%Reduced
Wellington Management Group LLP41,796$2.82M0.00%−5,085−10.8%Reduced
Wells Fargo & Company41,707$2.82M0.00%+8,527+25.7%Added
HighMark Wealth Management LLC39,716$2.68M0.90%−54,334−57.8%Reduced
Capital Fund Management S.A.39,142$2.64M0.02%+39,142New
Trexquant Investment LP35,404$2.39M0.01%−49,763−58.4%Reduced
Atom Investors LP33,917$2.29M0.20%+33,917New
Price T Rowe Associates Inc32,374$2.19M0.00%+2,683+9.0%Added
Swiss National Bank31,700$2.14M0.00%+4,100+14.9%Added
Voleon Capital Management LP31,425$2.12M0.04%+31,425New
Toroso Investments, LLC31,270$2.11M0.01%−5,082−14.0%Reduced
Tema ETFs LLC31,270$2.11M0.07%+201+0.6%Added
Moody Aldrich Partners LLC30,926$2.09M0.38%−8,529−21.6%Reduced
Aquatic Capital Management LLC30,813$2.08M0.07%+30,813New
SummitTX Capital, L.P.28,779$1.94M0.05%+28,779New
Alliancebernstein L.P.32,820$1.82M0.00%+1,500+4.8%Added
Rhumbline Advisers26,346$1.78M0.00%+2,498+10.5%Added
UBS Asset Management Americas Inc23,310$1.57M0.00%−7,417−24.1%Reduced
Burney Co22,557$1.52M0.04%+22,557New
Rafferty Asset Management, LLC21,864$1.48M0.00%−5,385−19.8%Reduced
XTX Topco Ltd21,411$1.45M0.02%−29,126−57.6%Reduced
Hussman Strategic Advisors, Inc.21,000$1.42M0.33%00.0%Unchanged
Tudor Investment Corp Et Al20,019$1.35M0.01%+15,057+303.4%Added
Credit Agricole S A20,000$1.35M0.00%00.0%Unchanged
Martingale Asset Management L P19,942$1.35M0.03%−8,200−29.1%Reduced
Creative Planning18,773$1.27M0.00%+1,937+11.5%Added
Y-Intercept (Hong Kong) Ltd18,468$1.25M0.02%−4,233−18.6%Reduced
California State Teachers Retirement System17,629$1.19M0.00%+3,629+25.9%Added
Los Angeles Capital Management LLC17,536$1.18M0.00%+1,872+12.0%Added
Virginia Retirement Systems Et Al17,250$1.16M0.01%+1,200+7.5%Added
Diametric Capital, LP16,868$1.14M0.12%+16,868New
Canada Pension Plan Investment Board16,500$1.11M0.00%+1,600+10.7%Added
Legal & General Group Plc16,415$1.11M0.00%+2,584+18.7%Added
Russell Investments Group, Ltd.16,301$1.10M0.00%+3,013+22.7%Added
Massachusetts Financial Services Co15,870$1.07M0.00%+15,870New
Cresset Asset Management, LLC14,412$972.8K0.00%+544+3.9%Added
Vanguard Global Advisers, LLC13,919$939.5K0.00%+2,165+18.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)13,405$904.8K0.00%+3,806+39.6%Added
Brevan Howard Capital Management LP13,329$899.7K0.01%+2,301+20.9%Added