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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Anaptysbio, Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
166
+19 vs. Q2 2025
Shares held
31.7M
−4.97M (−13.6%) vs. Q2 2025
Total value
$980.2M
+$166.8M (+20.5%) vs. Q2 2025
New holders
34
44 more added
Sold out
15
59 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 166 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ3 2025: $980.2M
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q2 2025.

Institutions holding ANAB in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC7,880,094$241.3M11.60%00.0%Unchanged
Point72 Asset Management, L.P.2,265,528$69.4M0.15%−209,346−8.5%Reduced
BlackRock, Inc.1,722,324$52.7M0.00%−64,610−3.6%Reduced
Morgan Stanley1,556,258$47.7M0.00%−313,582−16.8%Reduced
Millennium Management LLC1,519,230$46.5M0.04%+1,315,688+646.4%Added
Vanguard Group Inc1,476,989$45.2M0.00%−60,561−3.9%Reduced
Tang Capital Management LLC1,333,639$40.8M1.57%+2,760+0.2%Added
First Light Asset Management, LLC990,161$30.3M2.86%−2,549,432−72.0%Reduced
State Street Corp873,432$26.7M0.00%+52,401+6.4%Added
Assenagon Asset Management S.A.839,934$25.7M0.04%+822,975+4,852.7%Added
Sanofi821,917$25.2M9.67%00.0%Unchanged
Palo Alto Investors LP673,520$20.6M3.82%−139,301−17.1%Reduced
Soleus Capital Management, L.P.626,040$19.2M1.02%+305,000+95.0%Added
683 Capital Management, LLC547,000$16.7M1.52%+47,000+9.4%Added
Woodline Partners LP501,023$15.3M0.07%00.0%Unchanged
Geode Capital Management, LLC473,626$14.5M0.00%+10,268+2.2%Added
Franklin Resources Inc47,332$11.6M0.00%−307,176−86.6%Reduced
Jacobs Levy Equity Management, Inc378,452$11.6M0.05%+10,005+2.7%Added
Two Sigma Advisers, LP373,700$11.4M0.02%+83,300+28.7%Added
Arrowstreet Capital, Limited Partnership370,458$11.3M0.01%+219,648+145.6%Added
D. E. Shaw & Co., Inc.349,360$10.7M0.01%+237,011+211.0%Added
Nuveen, LLC339,271$10.4M0.00%+15,737+4.9%Added
Goldman Sachs Group Inc329,820$10.1M0.00%+49,985+17.9%Added
Price T Rowe Associates Inc299,311$9.17M0.00%−373,860−55.5%Reduced
Two Sigma Investments, LP256,420$7.85M0.01%+25,051+10.8%Added
Sofinnova Investments, Inc.254,268$7.79M0.48%−778,094−75.4%Reduced
Ensign Peak Advisors, Inc215,454$6.60M0.01%00.0%Unchanged
Charles Schwab Investment Management Inc206,441$6.32M0.00%+49,306+31.4%Added
Victory Capital Management Inc204,055$6.25M0.00%−328,030−61.6%Reduced
Northern Trust Corp195,563$5.99M0.00%−700−0.4%Reduced
Sectoral Asset Management Inc194,485$5.96M3.68%+110,585+131.8%Added
Federated Hermes, Inc.193,327$5.92M0.01%+185,053+2,236.6%Added
Jane Street Group, LLC181,112$5.55M0.01%+136,444+305.5%Added
Granahan Investment Management Inc147,773$4.52M0.19%+16,118+12.2%Added
Skandinaviska Enskilda Banken AB (publ)145,191$4.45M0.02%+111,668+333.1%Added
Susquehanna International Group, LLP144,604$4.43M0.01%−44,723−23.6%Reduced
HighMark Wealth Management LLC135,050$4.42M1.95%−10,500−7.2%Reduced
Bank of America Corp127,241$3.90M0.00%−949,558−88.2%Reduced
Renaissance Technologies LLC123,300$3.78M0.00%−139,786−53.1%Reduced
Trexquant Investment LP111,778$3.42M0.04%−87,464−43.9%Reduced
BNP Paribas Arbitrage, SA105,663$3.24M0.00%+101,964+2,756.5%Added
Macquarie Group Ltd93,732$2.87M0.00%00.0%Unchanged
Algert Global LLC83,767$2.56M0.04%+83,767New
Jump Financial, LLC82,077$2.51M0.03%+82,077New
UBS Group AG75,262$2.30M0.00%−1,197,237−94.1%Reduced
Citigroup Inc70,534$2.16M0.00%−975,954−93.3%Reduced
Squarepoint Ops LLC68,014$2.08M0.00%−41,374−37.8%Reduced
Wellington Management Group LLP66,731$2.04M0.00%−13,482−16.8%Reduced
Panagora Asset Management Inc63,857$1.96M0.01%+30,488+91.4%Added
Barclays PLC63,452$1.94M0.00%−36,547−36.5%Reduced
Fisher Asset Management, LLC58,878$1.80M0.00%−210.0%Reduced
Bank of New York Mellon Corp57,030$1.75M0.00%−2,195−3.7%Reduced
Walleye Capital LLC56,422$1.73M0.01%+56,422New
Marshall Wace, LLP54,416$1.67M0.00%+54,416New
FMR LLC53,162$1.63M0.00%−18,957−26.3%Reduced
Moody Aldrich Partners LLC49,882$1.53M0.29%−10,212−17.0%Reduced
Ikarian Capital, LLC48,410$1.48M0.34%+32,748+209.1%Added
DCF Advisers, LLC48,000$1.47M0.56%00.0%Unchanged
PDT Partners, LLC43,001$1.32M0.08%−1,464−3.3%Reduced
Invesco Ltd.42,381$1.30M0.00%−40,793−49.0%Reduced
Bleakley Financial Group, LLC39,981$1.22M0.03%+2,430+6.5%Added
Gsa Capital Partners LLP37,274$1.14M0.10%−32,525−46.6%Reduced
Susquehanna Portfolio Strategies, LLC35,448$1.09M0.02%+2,645+8.1%Added
Russell Investments Group, Ltd.34,032$1.04M0.00%+10,241+43.0%Added
UBS Asset Management Americas Inc33,271$1.02M0.00%−16,534−33.2%Reduced
Aquatic Capital Management LLC31,298$958.3K0.02%−34,512−52.4%Reduced
Alliancebernstein L.P.30,520$934.5K0.00%00.0%Unchanged
Rafferty Asset Management, LLC30,085$921.2K0.00%+3,256+12.1%Added
Rhumbline Advisers29,244$895.4K0.00%−1,461−4.8%Reduced
Engineers Gate Manager LP29,137$892.2K0.01%+4,392+17.7%Added
Swiss National Bank28,400$869.6K0.00%+2,000+7.6%Added
Boothbay Fund Management, LLC27,402$839.0K0.02%+27,402New
ExodusPoint Capital Management, LP26,500$811.4K0.01%+2,744+11.6%Added
Citadel Advisors LLC26,480$810.8K0.00%−91,806−77.6%Reduced
AQR Capital Management LLC26,174$801.4K0.00%−1,548−5.6%Reduced
Brevan Howard Capital Management LP25,299$774.7K0.01%+2,346+10.2%Added
HRT Financial LP25,025$766.0K0.00%+25,025New
Legal & General Group Plc19,504$597.2K0.00%00.0%Unchanged
Campbell & CO Investment Adviser LLC18,281$559.8K0.04%+18,281New
XTX Topco Ltd18,111$554.6K0.03%−12,531−40.9%Reduced
Creative Planning16,707$511.6K0.00%−147−0.9%Reduced
Cresset Asset Management, LLC15,753$482.4K0.00%+2,720+20.9%Added
Virtu Financial LLC15,531$476.0K0.03%+15,531New
Graham Capital Management, L.P.15,320$469.1K0.02%+15,320New
SEI Investments Co14,921$456.9K0.00%+14,921New
Los Angeles Capital Management LLC14,876$455.5K0.00%−151−1.0%Reduced
JPMorgan Chase & Co14,852$454.8K0.00%−232,773−94.0%Reduced
California State Teachers Retirement System14,215$435.3K0.00%−20.0%Reduced
Tudor Investment Corp Et Al13,869$424.7K0.00%+4,450+47.2%Added
Wells Fargo & Company13,743$420.8K0.00%−19,585−58.8%Reduced
Brinker Capital Investments, LLC13,739$420.7K0.00%+13,739New
Alps Advisors Inc13,335$408.3K0.00%−2,528−15.9%Reduced
Voya Investment Management LLC12,961$396.9K0.00%−60,044−82.2%Reduced
Man Group plc12,859$393.7K0.00%+12,859New
Deutsche Bank AG12,681$388.3K0.00%00.0%Unchanged
MetLife Investment Management11,928$365.2K0.00%+11,928New
NEOS Investment Management LLC10,975$336.1K0.00%−429−3.8%Reduced
Tema ETFs LLC10,975$336.1K0.03%−429−3.8%Reduced
New York State Common Retirement Fund10,586$324.1K0.00%+2,662+33.6%Added
Mirae Asset Global ETFs Holdings Ltd.10,667$315.2K0.00%+10,667New