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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Anaptysbio, Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
136
+9 vs. Q3 2021
Shares held
27.8M
+140.8K (+0.5%) vs. Q3 2021
Total value
$964.4M
+$215.6M (+28.8%) vs. Q3 2021
New holders
24
38 more added
Sold out
15
42 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 136 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ4 2021: $964.4M
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q3 2021.

Institutions holding ANAB in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC7,521,024$261.4M8.37%00.0%Unchanged
Tang Capital Management LLC2,628,678$91.3M18.37%00.0%Unchanged
BlackRock Inc.1,865,288$64.8M0.00%−5,889−0.3%Reduced
Vanguard Group Inc1,842,683$64.0M0.00%+13,453+0.7%Added
Federated Hermes, Inc.1,604,287$55.7M0.10%+662,014+70.3%Added
Boxer Capital, LLC1,300,000$45.2M1.80%00.0%Unchanged
Frazier Management LLC899,700$31.3M2.41%00.0%Unchanged
State Street Corp872,309$30.3M0.00%−94,558−9.8%Reduced
Dimensional Fund Advisors LP803,394$27.9M0.01%+47,902+6.3%Added
Woodline Partners LP609,981$21.2M0.31%−403,975−39.8%Reduced
Great Point Partners LLC592,250$20.6M4.60%+42,705+7.8%Added
Rock Springs Capital Management LP538,700$18.7M0.43%+2,868+0.5%Added
Palo Alto Investors LP436,592$15.2M0.97%00.0%Unchanged
Baker Bros. Advisors LP427,179$14.8M0.07%00.0%Unchanged
Nuveen Asset Management, LLC413,131$14.4M0.00%−7,818−1.9%Reduced
Geode Capital Management, LLC377,860$13.1M0.00%+18,928+5.3%Added
Blackstone Group Inc.328,720$11.4M0.03%00.0%Unchanged
Goldman Sachs Group Inc317,237$11.0M0.00%−30,385−8.7%Reduced
Northern Trust Corp281,970$9.80M0.00%−5,883−2.0%Reduced
Point72 Asset Management, L.P.257,145$8.94M0.04%+257,145New
JPMorgan Chase & Co236,338$8.21M0.00%−8,932−3.6%Reduced
D. E. Shaw & Co., Inc.212,681$7.39M0.01%−41,111−16.2%Reduced
Acadian Asset Management LLC190,150$6.60M0.02%+13,496+7.6%Added
Eversept Partners, LP182,612$6.35M0.53%+104,558+134.0%Added
Laurion Capital Management LP175,000$6.08M0.10%+175,000New
Natixis159,000$5.53M0.02%+159,000New
Charles Schwab Investment Management Inc136,312$4.74M0.00%+674+0.5%Added
Two Sigma Advisers, LP125,500$4.36M0.01%−44,400−26.1%Reduced
Los Angeles Capital Management LLC121,896$4.24M0.02%−8,664−6.6%Reduced
Cormorant Asset Management, LP100,000$3.48M0.21%−285,081−74.0%Reduced
Macquarie Group Ltd94,204$3.27M0.00%00.0%Unchanged
Jacobs Levy Equity Management, Inc89,317$3.10M0.02%+889+1.0%Added
Connor, Clark & Lunn Investment Management Ltd.88,069$3.06M0.01%+187+0.2%Added
Two Sigma Investments, LP86,532$3.01M0.01%−58,461−40.3%Reduced
Bank of New York Mellon Corp85,580$2.97M0.00%+3,544+4.3%Added
Massachusetts Financial Services Co81,204$2.82M0.00%−14,991−15.6%Reduced
Walleye Capital LLC77,784$2.70M0.09%+77,784New
Morgan Stanley72,727$2.53M0.00%+781+1.1%Added
Arrowstreet Capital, Limited Partnership72,501$2.52M0.00%+72,501New
Jupiter Asset Management Ltd58,954$2.08M0.02%00.0%Unchanged
Fisher Asset Management, LLC59,421$2.06M0.00%+13,402+29.1%Added
EAM Global Investors LLC58,683$2.04M0.36%+58,683New
Parametric Portfolio Associates LLC54,757$1.90M0.00%−2,522−4.4%Reduced
Ensign Peak Advisors, Inc44,832$1.56M0.00%+1,390+3.2%Added
Rafferty Asset Management, LLC43,362$1.51M0.01%+13,195+43.7%Added
Ameriprise Financial Inc42,475$1.48M0.00%+42,475New
EAM Investors, LLC40,392$1.40M0.23%+40,392New
Royal Bank of Canada40,066$1.39M0.00%+2,342+6.2%Added
Swiss National Bank39,200$1.36M0.00%00.0%Unchanged
AQR Capital Management LLC39,002$1.35M0.00%+12,657+48.0%Added
Citigroup Inc38,024$1.32M0.00%+15,474+68.6%Added
State of Wisconsin Investment Board37,700$1.31M0.00%+6,600+21.2%Added
Parkman Healthcare Partners LLC35,833$1.25M0.28%+35,833New
Renaissance Technologies LLC34,600$1.20M0.00%−34,100−49.6%Reduced
Alps Advisors Inc31,831$1.11M0.01%−1,792−5.3%Reduced
Rhumbline Advisers30,337$1.05M0.00%−310−1.0%Reduced
Alliancebernstein L.P.28,400$987.0K0.00%−2,000−6.6%Reduced
Allspring Global Investments Holdings, LLC27,307$948.0K0.00%+27,307New
Wells Fargo & Company26,649$926.0K0.00%−37,335−58.4%Reduced
UBS Group AG26,566$923.0K0.00%−1,395−5.0%Reduced
Panagora Asset Management Inc26,420$918.0K0.00%+342+1.3%Added
California State Teachers Retirement System25,468$885.0K0.00%+48+0.2%Added
Martingale Asset Management L P25,209$877.0K0.01%−8,305−24.8%Reduced
Ziegler Capital Management, LLC25,174$875.0K0.03%−8,031−24.2%Reduced
Susquehanna International Group, LLP23,572$819.0K0.00%+7,260+44.5%Added
Barclays PLC23,403$813.0K0.00%+11,674+99.5%Added
UBS Asset Management Americas Inc23,007$799.5K0.00%−1,307−5.4%Reduced
FMR LLC21,961$763.0K0.00%+21,563+5,417.8%Added
Principal Financial Group Inc21,700$754.0K0.00%+21,700New
Virginia Retirement Systems Et Al19,300$671.0K0.01%−9,100−32.0%Reduced
Invesco Ltd.19,214$668.0K0.00%−2,041−9.6%Reduced
Millennium Management LLC18,051$627.0K0.00%−114,658−86.4%Reduced
Russell Investments Group, Ltd.17,918$621.0K0.00%−471−2.6%Reduced
Putnam Investments LLC16,726$581.0K0.00%+16,726New
Franklin Resources Inc14,824$515.0K0.00%−76−0.5%Reduced
Credit Suisse AG14,703$511.0K0.00%+1,054+7.7%Added
Cubist Systematic Strategies, LLC13,718$477.0K0.00%+13,718New
New York State Common Retirement Fund12,828$446.0K0.00%−33−0.3%Reduced
State Board of Administration of Florida Retirement System11,936$415.0K0.00%−568−4.5%Reduced
Deutsche Bank AG11,712$407.0K0.00%+618+5.6%Added
Price T Rowe Associates Inc10,397$361.0K0.00%+2,257+27.7%Added
Manufacturers Life Insurance Company, The10,260$357.0K0.00%−410−3.8%Reduced
American International Group, Inc.10,246$356.0K0.00%−307−2.9%Reduced
Symmetry Investments LP10,208$355.0K0.18%+10,208New
International Biotechnology Trust PLC10,000$348.0K0.08%00.0%Unchanged
Bank of America Corp9,658$336.0K0.00%−4,580−32.2%Reduced
Susquehanna Fundamental Investments, LLC9,219$320.0K0.01%−6,000−39.4%Reduced
Hunter Perkins Capital Management, LLC9,130$317.0K0.06%00.0%Unchanged
STRS Ohio8,700$302.0K0.00%+8,700New
Legal & General Group Plc8,663$301.0K0.00%00.0%Unchanged
Institute for Wealth Management, LLC.8,115$282.0K0.05%−3,750−31.6%Reduced
ProShare Advisors LLC8,085$282.0K0.00%−246−3.0%Reduced
SEI Investments Co7,871$273.0K0.00%+36+0.5%Added
Voya Investment Management LLC7,780$270.0K0.00%−714−8.4%Reduced
Old Well Partners, LLC7,737$269.0K0.17%00.0%Unchanged
BNP Paribas Arbitrage, SA7,733$268.7K0.00%+2,724+54.4%Added
Dynamic Technology Lab Private Ltd7,535$262.0K0.03%+7,535New
Engineers Gate Manager LP7,100$247.0K0.01%+7,100New
MetLife Investment Management7,034$244.4K0.00%00.0%Unchanged
HRT Financial LP6,643$230.0K0.00%−25,082−79.1%Reduced