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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Anaptysbio, Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
118
+5 vs. Q3 2022
Shares held
32.9M
+317.6K (+1.0%) vs. Q3 2022
Total value
$1.02B
+$188.2M (+22.7%) vs. Q3 2022
New holders
15
34 more added
Sold out
10
38 more reduced

1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 118 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ4 2022: $1.02B
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q3 2022.

Institutions holding ANAB in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC7,521,024$233.1M7.10%00.0%Unchanged
Tang Capital Management LLC2,628,678$81.5M11.84%00.0%Unchanged
Federated Hermes, Inc.2,373,023$73.5M0.20%+1000.0%Added
Point72 Asset Management, L.P.2,124,200$65.8M0.25%−402,000−15.9%Reduced
BlackRock Inc.1,856,266$57.5M0.00%+88,469+5.0%Added
Vanguard Group Inc1,776,908$55.1M0.00%+31,800+1.8%Added
Boxer Capital, LLC1,300,000$40.3M2.17%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)1,161,826$36.0M0.75%−304,774−20.8%Reduced
State Street Corp1,101,181$34.1M0.00%−170,546−13.4%Reduced
Dimensional Fund Advisors LP942,132$29.2M0.01%+58,118+6.6%Added
Frazier Life Sciences Management, L.P.899,700$27.9M1.73%00.0%Unchanged
Baker Bros. Advisors LP775,924$24.0M0.14%+348,745+81.6%Added
Braidwell LP726,122$22.5M0.75%+726,122New
Assenagon Asset Management S.A.693,154$21.5M0.09%−143,700−17.2%Reduced
Woodline Partners LP647,545$20.1M0.28%−462,617−41.7%Reduced
Rock Springs Capital Management LP576,600$17.9M0.43%00.0%Unchanged
Palo Alto Investors LP431,024$13.4M1.14%00.0%Unchanged
Geode Capital Management, LLC391,764$12.1M0.00%+23,165+6.3%Added
5AM Venture Management, LLC357,733$11.1M2.98%+357,733New
Northern Trust Corp339,665$10.5M0.00%+3,568+1.1%Added
Blackstone Group Inc.328,720$10.2M0.04%00.0%Unchanged
Millennium Management LLC322,802$10.0M0.01%+294,750+1,050.7%Added
FMR LLC290,916$9.02M0.00%+186,831+179.5%Added
Citadel Advisors LLC280,542$8.69M0.01%−52,336−15.7%Reduced
Laurion Capital Management LP263,208$8.16M0.23%00.0%Unchanged
Logos Global Management LP250,000$7.75M0.91%+250,000New
JPMorgan Chase & Co214,084$6.63M0.00%−10,645−4.7%Reduced
D. E. Shaw & Co., Inc.174,198$5.40M0.01%−2,302−1.3%Reduced
Nuveen Asset Management, LLC159,694$4.95M0.00%−68,088−29.9%Reduced
Charles Schwab Investment Management Inc148,831$4.61M0.00%+3,343+2.3%Added
Goldman Sachs Group Inc107,575$3.33M0.00%+11,487+12.0%Added
Morgan Stanley95,916$2.97M0.00%−11,652−10.8%Reduced
ExodusPoint Capital Management, LP95,258$2.95M0.05%+59,017+162.8%Added
Macquarie Group Ltd93,732$2.90M0.00%00.0%Unchanged
Two Sigma Advisers, LP86,800$2.69M0.01%+30,500+54.2%Added
Bank of America Corp78,378$2.43M0.00%−2,671−3.3%Reduced
Fisher Asset Management, LLC77,550$2.40M0.00%00.0%Unchanged
Bank of New York Mellon Corp77,047$2.39M0.00%−7,057−8.4%Reduced
Rafferty Asset Management, LLC70,294$2.18M0.02%−7,366−9.5%Reduced
Jupiter Asset Management Ltd59,767$1.85M0.03%00.0%Unchanged
Ameriprise Financial Inc52,405$1.62M0.00%−885−1.7%Reduced
UBS Group AG51,791$1.61M0.00%+41,097+384.3%Added
Ensign Peak Advisors, Inc43,442$1.35M0.00%−4,800−9.9%Reduced
Swiss National Bank40,900$1.27M0.00%+800+2.0%Added
Barclays PLC40,351$1.25M0.00%−8,422−17.3%Reduced
FMB Wealth Management39,259$1.22M1.57%+39,259New
Deutsche Bank AG36,301$1.12M0.00%+2,221+6.5%Added
Citigroup Inc34,245$1.06M0.00%−36,877−51.9%Reduced
SG Americas Securities, LLC34,235$1.06M0.02%+13,214+62.9%Added
Rhumbline Advisers33,131$1.03M0.00%+499+1.5%Added
Alliancebernstein L.P.32,600$1.01M0.00%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.28,465$882.1K0.01%−37,369−56.8%Reduced
Two Sigma Investments, LP26,635$825.4K0.00%+26,635New
Martingale Asset Management L P26,117$809.4K0.02%+70.0%Added
California State Teachers Retirement System22,803$706.7K0.00%+251+1.1%Added
Jennison Associates LLC19,802$613.7K0.00%+19,802New
Credit Suisse AG19,380$600.6K0.00%+5,549+40.1%Added
Alps Advisors Inc19,286$597.7K0.01%+3,917+25.5%Added
Jump Financial, LLC18,730$580.4K0.03%+5,281+39.3%Added
Invesco Ltd.18,297$567.0K0.00%−16−0.1%Reduced
Ergoteles LLC18,224$564.8K0.02%+18,224New
New York State Common Retirement Fund17,142$531.2K0.00%+3,489+25.6%Added
State of Wisconsin Investment Board17,013$527.2K0.00%−1,043−5.8%Reduced
Squarepoint Ops LLC16,783$520.1K0.00%−21,926−56.6%Reduced
Susquehanna International Group, LLP16,330$506.1K0.00%−11,204−40.7%Reduced
BNP Paribas Arbitrage, SA15,790$489.3K0.00%−14,413−47.7%Reduced
Wellington Management Group LLP15,183$470.5K0.00%−651−4.1%Reduced
Great Point Partners LLC15,000$464.9K0.10%+15,000New
Soleus Capital Management, L.P.14,727$456.4K0.07%−49,300−77.0%Reduced
HighVista Strategies LLC14,004$434.0K0.26%−22,983−62.1%Reduced
HRT Financial LP13,013$403.0K0.01%+13,013New
Price T Rowe Associates Inc12,579$390.0K0.00%+320+2.6%Added
Walleye Capital LLC11,379$352.6K0.01%+11,379New
MetLife Investment Management11,043$342.2K0.00%00.0%Unchanged
Principal Financial Group Inc10,928$338.7K0.00%+80+0.7%Added
Virginia Retirement Systems Et Al10,800$334.7K0.00%+100+0.9%Added
James Investment Research Inc10,257$318.0K0.04%+3,732+57.2%Added
Jane Street Group, LLC9,647$299.0K0.00%+1,244+14.8%Added
American International Group, Inc.9,585$297.0K0.00%−35−0.4%Reduced
Legal & General Group Plc8,864$274.7K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System8,426$261.1K0.00%−1,360−13.9%Reduced
Voya Investment Management LLC8,281$256.6K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The8,085$250.6K0.00%−195−2.4%Reduced
Institute for Wealth Management, LLC.8,055$249.6K0.05%−3,492−30.2%Reduced
Public Employees Retirement Association of Colorado6,224$193.0K0.00%00.0%Unchanged
Fred Alger Management, LLC6,177$191.4K0.00%+6,177New
Virtus ETF Advisers LLC4,774$147.9K0.08%−253−5.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)2,539$78.7K0.00%−132−4.9%Reduced
Amalgamated Bank2,515$78.0K0.00%00.0%Unchanged
Royal Bank of Canada2,290$71.0K0.00%+1,359+146.0%Added
Ameritas Investment Partners, Inc.1,512$38.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co1,211$37.5K0.00%00.0%Unchanged
Amundi1,538$32.8K0.00%00.0%Unchanged
Russell Investments Group, Ltd.1,018$31.5K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC903$28.0K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC880$27.3K0.00%−20−2.2%Reduced
US Bancorp782$24.2K0.00%−756−49.2%Reduced
Great West Life Assurance Co750$23.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)429$13.0K0.00%−2,702−86.3%Reduced
Quadrant Capital Group LLC402$12.5K0.00%+86+27.2%Added