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Anaptysbio, Inc

ANAB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001370053

No open-market purchases or sales by Anaptysbio, Inc insiders were filed in the last 90 days; 213 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Anaptysbio, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
179
+13 vs. Q3 2025
Shares held
29.4M
−2.32M (−7.3%) vs. Q3 2025
Total value
$1.42B
+$442.7M (+45.2%) vs. Q3 2025
New holders
37
51 more added
Sold out
24
64 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANAB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 179 institutions
Q1 2021: 122 institutionsQ2 2021: 122 institutionsQ3 2021: 127 institutionsQ4 2021: 136 institutionsQ1 2022: 131 institutionsQ2 2022: 124 institutionsQ3 2022: 114 institutionsQ4 2022: 118 institutionsQ1 2023: 113 institutionsQ2 2023: 116 institutionsQ3 2023: 116 institutionsQ4 2023: 119 institutionsQ1 2024: 133 institutionsQ2 2024: 135 institutionsQ3 2024: 160 institutionsQ4 2024: 136 institutionsQ1 2025: 153 institutionsQ2 2025: 148 institutionsQ3 2025: 166 institutionsQ4 2025: 179 institutionsQ1 2026: 208 institutionsQ2 2026: 213 institutions
Value heldQ4 2025: $1.42B
Q1 2021: $628.6MQ2 2021: $720.6MQ3 2021: $748.8MQ4 2021: $964.4MQ1 2022: $735.4MQ2 2022: $632.6MQ3 2022: $830.6MQ4 2022: $1.02BQ1 2023: $675.4MQ2 2023: $614.9MQ3 2023: $544.5MQ4 2023: $646.4MQ1 2024: $658.1MQ2 2024: $746.6MQ3 2024: $1.13BQ4 2024: $468.9MQ1 2025: $742.8MQ2 2025: $816.2MQ3 2025: $980.2MQ4 2025: $1.42BQ1 2026: $1.55BQ2 2026: $2.03B
Institutions holding ANAB and their total value by quarter
QuarterHoldersValue
Q2 2026213$2.03B
Q1 2026208$1.55B
Q4 2025179$1.42B
Q3 2025166$980.2M
Q2 2025148$816.2M
Q1 2025153$742.8M
Q4 2024136$468.9M
Q3 2024160$1.13B
Q2 2024135$746.6M
Q1 2024133$658.1M
Q4 2023119$646.4M
Q3 2023116$544.5M
Q2 2023116$614.9M
Q1 2023113$675.4M
Q4 2022118$1.02B
Q3 2022114$830.6M
Q2 2022124$632.6M
Q1 2022131$735.4M
Q4 2021136$964.4M
Q3 2021127$748.8M
Q2 2021122$720.6M
Q1 2021122$628.6M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Anaptysbio, Inc; share changes are against Q3 2025.

Institutions holding ANAB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd5$00.00%−6,577−99.9%Reduced
CIBC Private Wealth Group, LLC1$480.00%00.0%Unchanged
IFP Advisors, Inc1$480.00%00.0%Unchanged
TFC Financial Management1$490.00%00.0%Unchanged
True Wealth Design, LLC4$1940.00%00.0%Unchanged
Sunbelt Securities, Inc.4$1940.00%00.0%Unchanged
SRS Capital Advisors, Inc.8$3880.00%+8New
MAI Capital Management10$4850.00%+10New
Massmutual Trust Co FSB12$5820.00%00.0%Unchanged
Stone House Investment Management, LLC13$6300.00%+8+160.0%Added
Ronald Blue Trust, Inc.19$9210.00%00.0%Unchanged
Parkside Financial Bank & Trust25$1.21K0.00%00.0%Unchanged
Essential Partners LLC33$1.60K0.00%00.0%Unchanged
Assetmark, Inc36$1.75K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC43$2.08K0.00%00.0%Unchanged
Optiver Holding B.V.54$2.62K0.00%−36−40.0%Reduced
Parallel Advisors, LLC55$2.67K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.65$3.15K0.00%+65New
Daiwa Securities Group Inc.75$4.00K0.00%−30−28.6%Reduced
UMA Financial Services, Inc.85$4.12K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.104$5.04K0.00%−6−5.5%Reduced
Sterling Capital Management LLC116$5.62K0.00%+69+146.8%Added
Aster Capital Management (DIFC) Ltd125$6.06K0.00%+125New
Basecamp Wealth Advisors LLC142$6.88K0.00%+142New
Allworth Financial LP143$6.93K0.00%−528−78.7%Reduced
Rothschild Investment LLC165$8.00K0.00%00.0%Unchanged
Quadrant Capital Group LLC175$8.48K0.00%00.0%Unchanged
Whittier Trust Co224$9.84K0.00%−9−3.9%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.238$12.0K0.00%−34−12.5%Reduced
Pinnacle Wealth Planning Services, Inc.334$16.2K0.00%+334New
Signaturefd, LLC352$17.1K0.00%00.0%Unchanged
GAMMA Investing LLC384$18.6K0.00%+35+10.0%Added
Farther Finance Advisors, LLC384$18.6K0.00%+109+39.6%Added
Versant Capital Management, Inc454$22.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.543$26.3K0.00%−59−9.8%Reduced
Amalgamated Bank580$28.0K0.00%−165−22.1%Reduced
Tower Research Capital LLC (TRC)727$35.2K0.00%−1,213−62.5%Reduced
Great West Life Assurance Co750$36.0K0.00%00.0%Unchanged
Smartleaf Asset Management LLC835$40.3K0.00%+821+5,864.3%Added
EverSource Wealth Advisors, LLC875$42.4K0.00%−90−9.3%Reduced
Nisa Investment Advisors, LLC963$46.7K0.00%−87−8.3%Reduced
CWM, LLC1,011$49.0K0.00%+2+0.2%Added
Mirae Asset Global Investments Co., Ltd.1,345$65.2K0.00%+263+24.3%Added
Bessemer Group Inc1,461$71.0K0.00%+33+2.3%Added
Caitong International Asset Management Co., Ltd1,530$74.2K0.02%+1,383+940.8%Added
Larson Financial Group LLC1,624$78.7K0.00%+284+21.2%Added
US Bancorp1,642$79.6K0.00%−148−8.3%Reduced
Ameritas Investment Partners, Inc.1,647$79.8K0.00%−270−14.1%Reduced
Royal Bank of Canada1,718$83.0K0.00%+1,560+987.3%Added
SBI Securities Co., Ltd.1,834$88.9K0.00%+1,830+45,750.0%Added
KLP Kapitalforvaltning AS3,000$145.4K0.00%00.0%Unchanged
Aquatic Capital Management LLC3,174$153.9K0.00%−28,124−89.9%Reduced
Latash Investments, LLC4,393$213.0K0.14%+4,393New
nVerses Capital, LLC4,438$215.2K0.48%+4,438New
ProShare Advisors LLC4,598$222.9K0.00%+4,598New
Public Employees Retirement Association of Colorado4,864$236.0K0.00%00.0%Unchanged
SEI Investments Co4,966$240.8K0.00%−9,955−66.7%Reduced
State Board of Administration of Florida Retirement System5,526$267.9K0.00%+5,526New
FMB Wealth Management5,592$271.1K0.11%+5,592New
Police & Firemen's Retirement System of New Jersey5,641$273.5K0.00%+1,082+23.7%Added
Ascent Group, LLC5,662$274.5K0.01%+5,662New
Manufacturers Life Insurance Company, The5,682$275.5K0.00%−1,037−15.4%Reduced
Acadian Asset Management LLC5,809$280.0K0.00%+5,809New
Virginia Retirement Systems Et Al5,850$283.6K0.00%+5,850New
Virtus Investment Advisers, Inc.5,919$287.0K0.08%+1,059+21.8%Added
Envestnet Asset Management Inc6,097$295.6K0.00%+6,097New
Savant Capital, LLC6,295$305.2K0.00%+6,295New
Quantinno Capital Management LP6,434$311.9K0.00%+6,434New
Duncan Williams Asset Management, LLC6,525$315.7K0.08%+6,525New
SummitTX Capital, L.P.6,528$316.5K0.01%+6,528New
Intech Investment Management LLC6,922$335.6K0.00%−883−11.3%Reduced
Glenmede Trust Co NA7,346$356.1K0.00%+7,346New
Janus Henderson Group PLC7,464$362.2K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.7,512$364.2K0.03%−2,395−24.2%Reduced
Quest Partners LLC7,761$376.3K0.02%−1,282−14.2%Reduced
Blueshift Asset Management, LLC7,852$380.7K0.11%+7,852New
Entropy Technologies, LP8,300$402.4K0.02%+8,300New
Bridgefront Capital, LLC8,549$414.5K0.10%+8,549New
State of Wisconsin Investment Board8,955$434.1K0.00%+8,955New
New York State Common Retirement Fund9,088$440.6K0.00%−1,498−14.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)9,286$450.2K0.00%+2,788+42.9%Added
MetLife Investment Management10,327$500.7K0.00%−1,601−13.4%Reduced
SG Americas Securities, LLC10,428$506.0K0.00%+10,428New
Mirae Asset Global ETFs Holdings Ltd.10,641$515.4K0.00%−26−0.2%Reduced
Gsa Capital Partners LLP10,695$518.0K0.04%−26,579−71.3%Reduced
Engineers Gate Manager LP10,880$527.5K0.01%−18,257−62.7%Reduced
JPMorgan Chase & Co10,916$529.2K0.00%−3,936−26.5%Reduced
Los Angeles Capital Management LLC15,101$550.7K0.00%+225+1.5%Added
Voya Investment Management LLC12,760$618.6K0.00%−201−1.6%Reduced
Profund Advisors LLC13,088$634.5K0.02%+6,525+99.4%Added
California State Teachers Retirement System14,138$685.4K0.00%−77−0.5%Reduced
Deutsche Bank AG14,381$697.2K0.00%+1,700+13.4%Added
Brinker Capital Investments, LLC14,697$712.5K0.01%+958+7.0%Added
Cresset Asset Management, LLC15,121$733.1K0.00%−632−4.0%Reduced
Creative Planning15,254$739.5K0.00%−1,453−8.7%Reduced
Algert Global LLC16,400$795.1K0.01%−67,367−80.4%Reduced
Tudor Investment Corp Et Al17,305$838.9K0.00%+3,436+24.8%Added
Legal & General Group Plc18,180$881.4K0.00%−1,324−6.8%Reduced
Russell Investments Group, Ltd.19,714$955.8K0.00%−14,318−42.1%Reduced
Panagora Asset Management Inc20,872$1.01M0.00%−42,985−67.3%Reduced