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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
793
−48 vs. Q4 2025
Shares held
131.4M
+14.7M (+12.6%) vs. Q4 2025
Total value
$43.4B
−$2.95B (−6.4%) vs. Q4 2025
New holders
106
323 more added
Sold out
154
258 more reduced

11 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 793 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2026: $43.4B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding ALNY in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
ING Groep NV1,289$426.5K0.00%−1,155−47.3%Reduced
Crossmark Global Holdings, Inc.1,293$427.8K0.01%+12+0.9%Added
Smartleaf Asset Management LLC1,361$430.2K0.02%+158+13.1%Added
Altfest L J & Co Inc1,317$435.8K0.05%−61−4.4%Reduced
Founders Financial Securities LLC1,361$437.3K0.02%+1,361New
Wealthcare Advisory Partners LLC1,330$440.1K0.01%+19+1.4%Added
Coldstream Capital Management Inc1,351$447.0K0.01%−223−14.2%Reduced
Virginia Retirement Systems Et Al1,360$450.0K0.00%+1,360New
AlphaCentric Advisors LLC1,370$453.3K0.45%+75+5.8%Added
Optimize Financial Inc1,381$456.9K0.22%+1,381New
Stephens Inc1,425$471.5K0.01%+580+68.6%Added
PSP Research LLC1,465$484.7K0.34%+147+11.2%Added
Qtron Investments LLC1,471$486.7K0.07%00.0%Unchanged
Regions Financial Corp1,473$487.4K0.00%+1,473New
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,533$493.8K0.00%00.0%Unchanged
High Net Worth Advisory Group LLC1,500$496.3K0.12%00.0%Unchanged
Aptus Capital Advisors, LLC1,513$500.6K0.00%+1,513New
Fulton Bank, N.A.1,549$512.5K0.02%+119+8.3%Added
Norden Group LLC1,553$513.8K0.05%+363+30.5%Added
Howard Capital Management Inc.1,570$519.5K0.01%−2,110−57.3%Reduced
Buckingham Strategic Partners1,582$522.6K0.01%−2,513−61.4%Reduced
Steward Partners Investment Advisory, LLC1,583$523.8K0.00%+158+11.1%Added
Independent Advisor Alliance1,602$530.1K0.01%+997+164.8%Added
Emerald Advisers, LLC1,622$536.7K0.02%00.0%Unchanged
Ballentine Partners, LLC1,639$542.3K0.01%−82−4.8%Reduced
Souders Financial Advisors1,644$544.0K0.06%+234+16.6%Added
Marks Group Wealth Management, Inc1,650$545.9K0.05%+1,650New
Fort Sheridan Advisors LLC1,701$562.8K0.07%00.0%Unchanged
Harbor Capital Advisors, Inc.1,704$564.0K0.05%+1,704New
Kepler Cheuvreux (Suisse) SA1,713$566.8K0.04%+1,713New
GraniteShares Advisors LLC1,755$580.7K0.42%−31−1.7%Reduced
Yousif Capital Management, LLC1,764$583.7K0.01%+88+5.3%Added
Capstone Capital Management Ltd1,767$584.6K0.59%−534−23.2%Reduced
Vise Technologies, Inc.1,515$602.4K0.01%00.0%Unchanged
Ellevest, Inc.1,837$607.8K0.08%+974+112.9%Added
Davenport & Co LLC1,842$609.5K0.00%+83+4.7%Added
Meeder Advisory Services, Inc.1,853$613.1K0.03%+15+0.8%Added
Unique Wealth Strategies, LLC1,854$613.3K0.25%+1,854New
Bannerman Wealth Management Group, LLC1,916$633.9K0.43%−31−1.6%Reduced
Cambridge Investment Research Advisors, Inc.1,927$638.0K0.00%−1,105−36.4%Reduced
Elm Partners Management LLC2,043$645.8K0.03%+35+1.7%Added
TD Waterhouse Canada Inc.1,971$647.1K0.00%+1,641+497.3%Added
Kovitz Investment Group Partners, LLC1,958$648.0K0.02%+3+0.2%Added
V-Square Quantitative Management LLC1,969$651.5K0.07%+11+0.6%Added
Tema ETFs LLC1,972$652.5K0.04%−24−1.2%Reduced
Caisse de Depot Et Placement du Quebec1,988$657.8K0.00%−49,610−96.1%Reduced
HB Wealth Management, LLC1,995$660.1K0.00%+294+17.3%Added
Security National Bank of So Dak2,000$661.7K0.32%00.0%Unchanged
Marex Group plc2,000$661.7K0.01%+2,000New
Hunting Hill Global Capital, LLC2,034$673.0K0.80%−2,225−52.2%Reduced
Archford Capital Strategies, LLC2,036$673.7K0.08%+12+0.6%Added
Signaturefd, LLC2,047$677.4K0.01%+66+3.3%Added
TCW Group Inc2,102$695.5K0.01%+102+5.1%Added
ICICI Prudential Asset Management Co Ltd2,197$726.9K0.09%+77+3.6%Added
Pallas Capital Advisors LLC2,212$731.9K0.03%−1,897−46.2%Reduced
Gateway Investment Advisers LLC2,251$744.8K0.01%−2,890−56.2%Reduced
Horizon Kinetics Asset Management LLC2,272$751.7K0.01%−104−4.4%Reduced
QRG Capital Management, Inc.2,277$753.5K0.01%−86−3.6%Reduced
GWM Advisors LLC2,316$766.3K0.00%−701−23.2%Reduced
Nixon Peabody Trust Co2,322$768.3K0.06%−15−0.6%Reduced
Cannon Global Investment Management, LLC2,400$794.1K1.92%+2,400New
Central Pacific Bank - Trust Division2,413$798.4K0.10%00.0%Unchanged
Westpac Banking Corp2,452$811.3K0.06%−2,859−53.8%Reduced
UniSuper Management Pty Ltd2,500$827.2K0.01%00.0%Unchanged
Sectoral Asset Management Inc2,310$864.2K0.72%−680−22.7%Reduced
J.Safra Asset Management Corp2,613$864.6K0.05%+974+59.4%Added
Horizon Investments, LLC2,632$870.9K0.01%+2,181+483.6%Added
Walleye Capital LLC2,639$873.2K0.01%−3,329−55.8%Reduced
Financiere des Professionnels - Fonds d,investissement inc.2,689$889.7K0.05%00.0%Unchanged
Perpetual Ltd2,690$890.0K0.01%−2,349−46.6%Reduced
Regal Investment Advisors LLC2,691$890.5K0.05%−23−0.8%Reduced
RSM US Wealth Management LLC2,711$896.9K0.01%+136+5.3%Added
Private Advisory Group LLC2,729$902.9K0.06%+574+26.6%Added
Shepherd Financial Partners LLC2,736$905.3K0.09%00.0%Unchanged
Flputnam Investment Management Co2,741$906.9K0.01%+2,741New
Theory Financial LLC2,744$907.9K0.32%00.0%Unchanged
Principal Securities, Inc.2,745$908.2K0.01%+119+4.5%Added
Park Avenue Securities LLC2,796$925.0K0.01%+405+16.9%Added
Hall Laurie J Trustee2,812$930.4K0.33%00.0%Unchanged
Anchor Investment Management, LLC2,819$932.7K0.08%+124+4.6%Added
Robertson Stephens Wealth Management, LLC2,836$938.4K0.03%+36+1.3%Added
Siemens Fonds Invest GmbH2,838$939.0K0.05%+1,001+54.5%Added
Orion Capital Management LLC2,855$944.6K0.33%−112−3.8%Reduced
Western Financial Corp2,866$948.3K0.37%+135+4.9%Added
Havemeyer Place LP2,878$952.2K0.11%+2,580+865.8%Added
Generali Investments CEE, investicni spolecnost, a.s.2,900$959.5K0.05%00.0%Unchanged
Everhart Financial Group, Inc.2,901$959.9K0.08%+360+14.2%Added
Merit Financial Group, LLC2,903$960.5K0.01%−1,608−35.6%Reduced
Prudential Financial Inc2,956$978.1K0.00%−10,353−77.8%Reduced
SBI Okasan Asset Management Co.Ltd.3,100$979.9K0.04%−190−5.8%Reduced
Everence Capital Management Inc2,970$983.0K0.06%00.0%Unchanged
Gsa Capital Partners LLP2,990$989.0K0.06%+2,990New
Callan Family Office, LLC3,035$1.00M0.02%−579−16.0%Reduced
Grandfield & Dodd, LLC3,081$1.02M0.06%−48−1.5%Reduced
Sanders Morris Harris LLC3,150$1.04M0.17%+3,150New
Brandywine Managers, LLC3,168$1.05M0.62%−450−12.4%Reduced
Generali Asset Management SPA SGR3,193$1.06M0.02%+3,143+6,286.0%Added
J. Safra Sarasin Holding AG3,230$1.07M0.02%−5,908−64.7%Reduced
Wiley Bros.-Aintree Capital, LLC3,230$1.07M0.01%+533+19.8%Added
Keybank National Association3,239$1.07M0.00%−96−2.9%Reduced