Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Shelton Capital Management | 15,064 | $5.99M | 0.12% | +15,064 | New |
| Mutual of America Capital Management LLC | 15,466 | $6.15M | 0.06% | +159+1.0% | Added |
| Profund Advisors LLC | 15,589 | $6.20M | 0.19% | +12,053+340.9% | Added |
| Oppenheimer Asset Management Inc. | 15,592 | $6.20M | 0.08% | +11,292+262.6% | Added |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 15,869 | $6.31M | 0.05% | +43+0.3% | Added |
| Assetmark, Inc | 16,033 | $6.38M | 0.01% | +4,115+34.5% | Added |
| Entropy Technologies, LP | 16,097 | $6.40M | 0.35% | −1,084−6.3% | Reduced |
| Prosight Management, LP | 17,109 | $6.80M | 1.41% | +17,109 | New |
| Artia Global Partners LP | 17,400 | $6.92M | 1.11% | −17,170−49.7% | Reduced |
| Elo Mutual Pension Insurance Co | 17,441 | $6.94M | 0.11% | −424−2.4% | Reduced |
| Cetera Investment Advisers | 17,549 | $6.98M | 0.01% | +3,026+20.8% | Added |
| MML Investors Services, LLC | 17,650 | $7.02M | 0.02% | −2,028−10.3% | Reduced |
| iA Global Asset Management Inc. | 17,780 | $7.07M | 0.09% | +16,133+979.5% | Added |
| Vinva Investment Management Ltd | 17,961 | $7.14M | 0.09% | +16,703+1,327.7% | Added |
| Silvant Capital Management LLC | 17,964 | $7.14M | 0.24% | +288+1.6% | Added |
| Wealthfront Advisers LLC | 18,254 | $7.26M | 0.02% | +4,834+36.0% | Added |
| Liontrust Investment Partners LLP | 18,387 | $7.31M | 0.11% | +6,731+57.7% | Added |
| Police & Firemen's Retirement System of New Jersey | 19,295 | $7.67M | 0.06% | −798−4.0% | Reduced |
| Empowered Funds, LLC | 19,431 | $7.73M | 0.13% | +15,146+353.5% | Added |
| Teacher Retirement System of Texas | 20,035 | $7.97M | 0.03% | −13,607−40.4% | Reduced |
| AIA Group Ltd | 20,177 | $8.02M | 0.12% | −13,136−39.4% | Reduced |
| Engineers Gate Manager LP | 20,199 | $8.03M | 0.10% | −23,650−53.9% | Reduced |
| Stifel Financial Corp | 20,427 | $8.12M | 0.01% | +132+0.7% | Added |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 20,482 | $8.14M | 0.29% | +20,482 | New |
| Thrivent Financial for Lutherans | 20,641 | $8.21M | 0.01% | +20,641 | New |
| Utah Retirement Systems | 20,725 | $8.24M | 0.08% | +126+0.6% | Added |
| Capital Fund Management S.A. | 20,940 | $8.33M | 0.08% | +20,940 | New |
| Avidity Partners Management LP | 21,000 | $8.35M | 2.41% | +21,000 | New |
| Acadian Asset Management LLC | 21,308 | $8.47M | 0.01% | +2,225+11.7% | Added |
| Investment Management Corp of Ontario | 21,535 | $8.56M | 0.11% | −16,423−43.3% | Reduced |
| Credit Agricole S A | 21,540 | $8.57M | 0.02% | +9,173+74.2% | Added |
| Banco Bilbao Vizcaya Argentaria, S.A. | 21,926 | $8.72M | 0.06% | −309−1.4% | Reduced |
| Nomura Holdings Inc | 22,437 | $8.92M | 0.03% | +20,711+1,199.9% | Added |
| Swiss Life Asset Management Ltd | 22,472 | $8.94M | 0.05% | +951+4.4% | Added |
| Toronto Dominion Bank | 23,199 | $9.23M | 0.02% | +1,972+9.3% | Added |
| British Columbia Investment Management Corp | 23,220 | $9.23M | 0.05% | +4,481+23.9% | Added |
| CI Private Wealth, LLC | 23,763 | $9.45M | 0.01% | −15,629−39.7% | Reduced |
| Creative Planning | 23,815 | $9.47M | 0.01% | +953+4.2% | Added |
| Eurizon Capital SGR S.p.A. | 24,410 | $9.71M | 0.03% | +24,410 | New |
| Cerity Partners LLC | 24,578 | $9.77M | 0.01% | −2,851−10.4% | Reduced |
| Brown Advisory Inc | 24,858 | $9.88M | 0.01% | −1,734−6.5% | Reduced |
| Mizuho Markets Cayman LP | 24,958 | $9.92M | 0.50% | +24,958 | New |
| China Universal Asset Management Co., Ltd. | 25,267 | $10.0M | 0.77% | +2,480+10.9% | Added |
| Macquarie Group Ltd | 25,281 | $10.1M | 0.04% | −623,063−96.1% | Reduced |
| CWM, LLC | 25,475 | $10.1M | 0.03% | −3,812−13.0% | Reduced |
| Assenagon Asset Management S.A. | 25,590 | $10.2M | 0.02% | −54,791−68.2% | Reduced |
| Quantinno Capital Management LP | 25,592 | $10.2M | 0.02% | +6,327+32.8% | Added |
| Illinois Municipal Retirement Fund | 25,771 | $10.2M | 0.13% | −1,374−5.1% | Reduced |
| Daiwa Securities Group Inc. | 25,999 | $10.3M | 0.03% | +10,503+67.8% | Added |
| Erste Asset Management GmbH | 26,010 | $10.4M | 0.09% | 00.0% | Unchanged |
| Varma Mutual Pension Insurance Co | 26,100 | $10.4M | 0.06% | +26,100 | New |
| USS Investment Management Ltd | 26,224 | $10.4M | 0.05% | −142−0.5% | Reduced |
| IFM Investors Pty Ltd | 26,238 | $10.4M | 0.09% | +197+0.8% | Added |
| Jefferies Financial Group Inc. | 26,322 | $10.5M | 0.09% | +9,780+59.1% | Added |
| EFG International AG | 26,400 | $10.5M | 0.20% | +26,400 | New |
| Trexquant Investment LP | 26,741 | $10.6M | 0.09% | +14,345+115.7% | Added |
| Xponance, Inc. | 27,328 | $10.9M | 0.08% | +1,176+4.5% | Added |
| U.S. Capital Wealth Advisors, LLC | 27,343 | $10.9M | 0.28% | −201−0.7% | Reduced |
| STRS Ohio | 28,036 | $11.1M | 0.04% | +51+0.2% | Added |
| CIBC Asset Management Inc | 29,832 | $11.9M | 0.03% | +24,334+442.6% | Added |
| Oddo BHF Asset Management SAS | 30,133 | $12.0M | 0.45% | −7,794−20.6% | Reduced |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 30,215 | $12.0M | 0.10% | 00.0% | Unchanged |
| Zurich Insurance Group Ltd | 30,322 | $12.1M | 0.08% | +334+1.1% | Added |
| GF Fund Management Co. Ltd. | 30,462 | $12.1M | 0.21% | +27,665+989.1% | Added |
| Jump Financial, LLC | 30,562 | $12.2M | 0.15% | −4,315−12.4% | Reduced |
| DnB Asset Management AS | 30,707 | $12.2M | 0.04% | −3,561−10.4% | Reduced |
| Panagora Asset Management Inc | 30,843 | $12.3M | 0.04% | −31,511−50.5% | Reduced |
| Teachers Retirement System of the State of Kentucky | 31,616 | $12.6M | 0.09% | −1,202−3.7% | Reduced |
| Rosenblum Silverman Sutton S F Inc | 33,180 | $13.2M | 3.05% | −822−2.4% | Reduced |
| Eventide Asset Management, LLC | 34,035 | $13.5M | 0.21% | −67,704−66.5% | Reduced |
| Bank of Montreal | 35,116 | $14.0M | 0.01% | +25,183+253.5% | Added |
| PFA Pension, Forsikringsaktieselskab | 35,405 | $14.1M | 0.04% | +35,405 | New |
| Lord, Abbett & Co. LLC | 35,406 | $14.1M | 0.04% | −31,814−47.3% | Reduced |
| Nissay Asset Management Corp | 35,813 | $14.2M | 0.07% | +19,238+116.1% | Added |
| Groupama Asset Managment | 35,878 | $14.3M | 0.21% | +3,796+11.8% | Added |
| PensionDanmark Pensionsforsikringsaktieselskab | 36,262 | $14.4M | 0.13% | +36,262 | New |
| Arizona State Retirement System | 36,390 | $14.5M | 0.08% | −2,122−5.5% | Reduced |
| Polymer Capital Management (HK) LTD | 36,765 | $14.6M | 2.28% | +7,865+27.2% | Added |
| Citadel Advisors LLC | 38,459 | $15.3M | 0.01% | −183,384−82.7% | Reduced |
| Bronte Capital Management Pty Ltd. | 38,864 | $15.5M | 1.62% | +3,890+11.1% | Added |
| Resona Asset Management Co.,Ltd. | 39,247 | $15.6M | 0.08% | −2,250−5.4% | Reduced |
| Gotham Asset Management, LLC | 39,622 | $15.8M | 0.06% | +11,487+40.8% | Added |
| Natixis | 39,779 | $15.8M | 0.06% | +39,779 | New |
| Guggenheim Capital LLC | 40,135 | $16.0M | 0.12% | +31,510+365.3% | Added |
| Tredje AP-fonden | 40,447 | $16.1M | 0.12% | +26,991+200.6% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 40,459 | $16.1M | 0.03% | +40,459 | New |
| NEOS Investment Management LLC | 40,701 | $16.2M | 0.09% | +38,138+1,488.0% | Added |
| Lansforsakringar Fondforvaltning AB (publ) | 42,340 | $16.8M | 0.08% | −64−0.2% | Reduced |
| Mediolanum International Funds Ltd | 42,476 | $16.9M | 0.17% | +17,025+66.9% | Added |
| Mariner, LLC | 42,443 | $16.9M | 0.02% | +16,111+61.2% | Added |
| Alliancebernstein L.P. | 44,319 | $17.6M | 0.01% | +543+1.2% | Added |
| Natixis Advisors, L.P. | 44,335 | $17.6M | 0.02% | +22,653+104.5% | Added |
| Public Employees Retirement System of Ohio | 44,498 | $17.7M | 0.06% | +5,504+14.1% | Added |
| Parnassus Investments | 44,560 | $17.7M | 0.05% | +7,546+20.4% | Added |
| Advisor Group Holdings, Inc. | 44,718 | $17.8M | 0.03% | +19,780+79.3% | Added |
| Schonfeld Strategic Advisors LLC | 44,894 | $17.9M | 0.09% | +35,185+362.4% | Added |
| State of New Jersey Common Pension Fund D | 44,976 | $17.9M | 0.06% | −556−1.2% | Reduced |
| Rafferty Asset Management, LLC | 45,031 | $17.9M | 0.06% | +27,880+162.6% | Added |
| Rhenman & Partners Asset Management AB | 45,675 | $18.2M | 1.70% | +13,800+43.3% | Added |
| DekaBank Deutsche Girozentrale | 113,193 | $18.2M | 0.03% | 00.0% | Unchanged |