Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| North Dakota State Investment Board | 4,789 | $1.90M | 0.07% | +4,789 | New |
| AustralianSuper Pty Ltd | 4,803 | $1.91M | 0.01% | −939−16.4% | Reduced |
| Toroso Investments, LLC | 4,825 | $1.92M | 0.01% | −2,066−30.0% | Reduced |
| West Michigan Advisors, LLC | 4,999 | $1.99M | 0.46% | −397−7.4% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 5,005 | $1.99M | 0.03% | 00.0% | Unchanged |
| Tokio Marine Asset Management Co Ltd | 5,015 | $1.99M | 0.07% | +571+12.8% | Added |
| Perpetual Ltd | 5,039 | $2.00M | 0.03% | +5,039 | New |
| Gateway Investment Advisers LLC | 5,141 | $2.04M | 0.02% | 00.0% | Unchanged |
| Vident Advisory, LLC | 5,155 | $2.05M | 0.02% | −82−1.6% | Reduced |
| US Bancorp | 5,236 | $2.08M | 0.00% | −410−7.3% | Reduced |
| B. Metzler seel. Sohn & Co. AG | 5,252 | $2.09M | 0.02% | +1,339+34.2% | Added |
| Genus Capital Management Inc. | 5,255 | $2.09M | 0.24% | −3,005−36.4% | Reduced |
| Westpac Banking Corp | 5,311 | $2.11M | 0.13% | +3,956+292.0% | Added |
| Diadema Partners LP | 5,341 | $2.12M | 1.26% | −4,659−46.6% | Reduced |
| AG2R la Mondiale Gestion D'Actifs | 5,595 | $2.22M | 0.10% | −230−3.9% | Reduced |
| Abn Amro Investment Solutions | 5,759 | $2.29M | 0.03% | +4,449+339.6% | Added |
| Tower Research Capital LLC (TRC) | 5,841 | $2.32M | 0.06% | +4,304+280.0% | Added |
| Walleye Capital LLC | 5,968 | $2.37M | 0.01% | −16,377−73.3% | Reduced |
| Bridgeway Capital Management, LLC | 5,990 | $2.38M | 0.05% | −40−0.7% | Reduced |
| Kestra Investment Management, LLC | 6,014 | $2.39M | 0.06% | +6,014 | New |
| Ci Investments Inc. | 6,052 | $2.41M | 0.01% | −1,172−16.2% | Reduced |
| Truist Financial Corp | 6,105 | $2.43M | 0.00% | −361−5.6% | Reduced |
| Pathstone Holdings, LLC | 6,139 | $2.44M | 0.01% | −158−2.5% | Reduced |
| Atria Investments LLC | 6,173 | $2.45M | 0.03% | +979+18.8% | Added |
| Dai-Ichi Life Insurance Company, Ltd | 6,255 | $2.49M | 0.06% | +800+14.7% | Added |
| Plato Investment Management Ltd | 6,254 | $2.50M | 0.16% | +1,348+27.5% | Added |
| Hussman Strategic Advisors, Inc. | 6,300 | $2.51M | 0.61% | +6,300 | New |
| Maryland State Retirement & Pension System | 6,346 | $2.52M | 0.05% | +160+2.6% | Added |
| Janney Montgomery Scott LLC | 6,503 | $2.59M | 0.01% | +2,448+60.4% | Added |
| Sanctuary Advisors, LLC | 6,520 | $2.59M | 0.01% | +345+5.6% | Added |
| Gulf International Bank (UK) Ltd | 6,627 | $2.63M | 0.09% | +249+3.9% | Added |
| Dark Forest Capital Management LP | 6,715 | $2.67M | 0.12% | −4,883−42.1% | Reduced |
| PKO Investment Management Joint-Stock Co | 6,800 | $2.70M | 0.22% | +6,000+750.0% | Added |
| Colony Group, LLC | 7,083 | $2.82M | 0.00% | +466+7.0% | Added |
| J.P. Marvel Investment Advisors, LLC | 7,105 | $2.83M | 0.39% | 00.0% | Unchanged |
| Edgestream Partners, L.P. | 7,248 | $2.88M | 0.08% | +7,248 | New |
| NewEdge Wealth, LLC | 7,530 | $2.99M | 0.03% | −463−5.8% | Reduced |
| Osmosis Investment Management UK Ltd | 7,707 | $3.06M | 0.08% | +7,707 | New |
| Bank of Nova Scotia | 7,749 | $3.08M | 0.00% | +1,805+30.4% | Added |
| La Banque Postale Asset Management SA | 7,790 | $3.10M | 0.04% | −394−4.8% | Reduced |
| Prudential PLC | 7,829 | $3.11M | 0.02% | +133+1.7% | Added |
| Kentucky Retirement Systems | 7,836 | $3.12M | 0.08% | 00.0% | Unchanged |
| St Germain D J Co Inc | 7,857 | $3.12M | 0.12% | −294−3.6% | Reduced |
| M&T Bank Corp | 7,966 | $3.17M | 0.01% | +1,164+17.1% | Added |
| Advisory Services Network, LLC | 8,093 | $3.22M | 0.05% | +1,087+15.5% | Added |
| Rockefeller Capital Management L.P. | 8,124 | $3.23M | 0.01% | +3,744+85.5% | Added |
| MetLife Investment Management | 8,187 | $3.26M | 0.02% | +195+2.4% | Added |
| S&CO Inc | 8,200 | $3.26M | 0.20% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 8,606 | $3.42M | 0.29% | +8,529+11,076.6% | Added |
| Walleye Trading LLC | 8,657 | $3.44M | 0.06% | +7,062+442.8% | Added |
| Vestmark Advisory Solutions, Inc. | 8,778 | $3.49M | 0.05% | +7,693+709.0% | Added |
| Louisiana State Employees Retirement System | 8,800 | $3.50M | 0.06% | +8,800 | New |
| Keystone Investors Pte Ltd | 8,880 | $3.53M | 0.32% | +8,880 | New |
| Capstone Investment Advisors, LLC | 8,918 | $3.55M | 0.03% | +7,687+624.5% | Added |
| Martingale Asset Management L P | 9,124 | $3.63M | 0.09% | +9,124 | New |
| J. Safra Sarasin Holding AG | 9,138 | $3.63M | 0.06% | −384−4.0% | Reduced |
| Campbell & CO Investment Adviser LLC | 9,490 | $3.77M | 0.18% | −3,207−25.3% | Reduced |
| Pacer Advisors, Inc. | 9,588 | $3.81M | 0.01% | +9,588 | New |
| Nisa Investment Advisors, LLC | 9,649 | $3.84M | 0.01% | −2,484−20.5% | Reduced |
| Commonwealth Equity Services, LLC | 9,745 | $3.87M | 0.01% | +338+3.6% | Added |
| Blair William & Co | 9,774 | $3.89M | 0.01% | −470−4.6% | Reduced |
| Employees Retirement System of Texas | 9,792 | $3.89M | 0.03% | 00.0% | Unchanged |
| Allstate Corp | 9,829 | $3.91M | 0.05% | +5,258+115.0% | Added |
| O'Shaughnessy Asset Management, LLC | 9,927 | $3.95M | 0.02% | +619+6.7% | Added |
| Lazard Asset Management LLC | 10,152 | $4.04M | 0.01% | +401+4.1% | Added |
| Himension Fund | 10,185 | $4.05M | 0.25% | +91+0.9% | Added |
| Harvest Fund Management Co., Ltd | 10,319 | $4.10M | 0.15% | +8,298+410.6% | Added |
| Atika Capital Management LLC | 10,339 | $4.11M | 0.57% | −11,867−53.4% | Reduced |
| Silvercrest Asset Management Group LLC | 10,410 | $4.14M | 0.03% | −397−3.7% | Reduced |
| Commerce Bank | 10,533 | $4.19M | 0.02% | +6,002+132.5% | Added |
| Amalgamated Bank | 10,679 | $4.25M | 0.03% | +535+5.3% | Added |
| CIBC World Markets Corp | 10,965 | $4.36M | 0.02% | +10,965 | New |
| ASR Vermogensbeheer N.V. | 11,022 | $4.38M | 0.05% | +2,146+24.2% | Added |
| Cullen/Frost Bankers, Inc. | 11,033 | $4.39M | 0.05% | −10−0.1% | Reduced |
| Banque Cantonale Vaudoise | 11,037 | $4.39M | 0.16% | +6,177+127.1% | Added |
| Kornitzer Capital Management Inc | 11,114 | $4.42M | 0.09% | −12,575−53.1% | Reduced |
| Hantz Financial Services, Inc. | 11,323 | $4.50M | 0.07% | −1,823−13.9% | Reduced |
| Raiffeisen Bank International AG | 11,506 | $4.57M | 0.06% | −103−0.9% | Reduced |
| Traynor Capital Management, Inc. | 11,570 | $4.60M | 0.25% | +697+6.4% | Added |
| Mercer Global Advisors Inc | 11,786 | $4.69M | 0.01% | +302+2.6% | Added |
| Zacks Investment Management | 12,008 | $4.77M | 0.04% | +104+0.9% | Added |
| CIBC World Markets Inc. | 12,225 | $4.86M | 0.01% | +109+0.9% | Added |
| Mackenzie Financial Corp | 12,395 | $4.91M | 0.01% | +2,622+26.8% | Added |
| Public Employees Retirement Association of Colorado | 12,445 | $4.95M | 0.02% | 00.0% | Unchanged |
| Ilmarinen Mutual Pension Insurance Co | 12,500 | $4.97M | 0.04% | −8,500−40.5% | Reduced |
| Motley Fool Asset Management LLC | 12,526 | $4.98M | 0.19% | +3,480+38.5% | Added |
| Federation des caisses Desjardins du Quebec | 12,549 | $4.99M | 0.02% | −2,078−14.2% | Reduced |
| Alberta Investment Management Corp | 12,600 | $5.01M | 0.03% | +900+7.7% | Added |
| The PNC Financial Services Group, Inc. | 12,678 | $5.04M | 0.00% | −437−3.3% | Reduced |
| Rakuten Investment Management, Inc. | 12,684 | $5.06M | 0.02% | −18,468−59.3% | Reduced |
| Nordea Investment Management AB | 12,855 | $5.12M | 0.00% | +374+3.0% | Added |
| Capula Management Ltd | 13,181 | $5.24M | 0.03% | +6,293+91.4% | Added |
| Captrust Financial Advisors | 13,255 | $5.27M | 0.01% | +5,586+72.8% | Added |
| Prudential Financial Inc | 13,309 | $5.29M | 0.01% | +4,177+45.7% | Added |
| JustInvest LLC | 13,727 | $5.46M | 0.05% | −258−1.8% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 14,087 | $5.74M | 0.01% | −438−3.0% | Reduced |
| OP Asset Management Ltd | 14,770 | $5.87M | 0.07% | +384+2.7% | Added |
| Capital Group Investment Management Pte. Ltd. | 14,846 | $5.90M | 0.96% | −2,017−12.0% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 14,869 | $5.91M | 0.05% | +8,164+121.8% | Added |
| MUFG Securities EMEA plc | 15,000 | $5.96M | 0.07% | +15,000 | New |