Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Atomi Financial Group, Inc. | 907 | $360.8K | 0.01% | −35−3.7% | Reduced |
| denkapparat Operations GmbH | 912 | $362.7K | 0.20% | +912 | New |
| HCR Wealth Advisors | 924 | $367.4K | 0.04% | 00.0% | Unchanged |
| Thayer Partners, LLC | 927 | $368.6K | 0.18% | +927 | New |
| Prelude Capital Management, LLC | 928 | $369.0K | 0.03% | +928 | New |
| Aaron Wealth Advisors | 932 | $370.6K | 0.02% | −177−16.0% | Reduced |
| Picton Mahoney Asset Management | 932 | $370.6K | 0.00% | +932 | New |
| Ostrum Asset Management | 947 | $376.6K | 0.02% | +566+148.6% | Added |
| Cynosure Management, LLC | 950 | $377.8K | 0.04% | +950 | New |
| Optimist Retirement Group LLC | 962 | $382.5K | 0.18% | +962 | New |
| Generali Investments, Management Co LLC | 965 | $383.7K | 0.08% | +965 | New |
| Oppenheimer & Co Inc | 966 | $384.1K | 0.01% | −750−43.7% | Reduced |
| CAPROCK Group, Inc. | 992 | $394.5K | 0.01% | +135+15.8% | Added |
| Calamos Advisors LLC | 1,000 | $397.6K | 0.00% | −200−16.7% | Reduced |
| Westmount Partners, LLC | 1,000 | $397.6K | 0.10% | 00.0% | Unchanged |
| Livforsakringsbolaget Skandia, Omsesidigt | 1,000 | $397.6K | 0.02% | 00.0% | Unchanged |
| Parcion Private Wealth LLC | 1,002 | $398.4K | 0.02% | +213+27.0% | Added |
| Breakwater Capital Group | 1,007 | $400.4K | 0.06% | −20−1.9% | Reduced |
| Waddell & Associates, LLC | 1,017 | $404.4K | 0.03% | −1−0.1% | Reduced |
| Asahi Life Asset Management Co., Ltd. | 1,033 | $410.8K | 0.23% | −10−1.0% | Reduced |
| Nichols & Pratt Advisers LLP | 1,039 | $413.2K | 0.03% | −4−0.4% | Reduced |
| Elevate Capital Advisors, LLC | 1,039 | $413.2K | 0.27% | +1,039 | New |
| Prosperity Consulting Group, LLC | 1,041 | $414.0K | 0.02% | +1,041 | New |
| Coastal Bridge Advisors, LLC | 1,048 | $416.7K | 0.03% | −49−4.5% | Reduced |
| Sentinus, LLC | 1,051 | $417.9K | 0.04% | +1,051 | New |
| EverSource Wealth Advisors, LLC | 1,061 | $421.9K | 0.02% | −69−6.1% | Reduced |
| Capital Group Private Client Services, Inc. | 1,070 | $425.5K | 0.01% | 00.0% | Unchanged |
| North Star Asset Management Inc | 1,105 | $439.4K | 0.02% | −200−15.3% | Reduced |
| Simplify Asset Management Inc. | 1,109 | $441.0K | 0.01% | +335+43.3% | Added |
| Abel Hall, LLC | 1,111 | $441.8K | 0.10% | +1,111 | New |
| Banque Pictet & Cie SA | 1,120 | $445.4K | 0.00% | −265−19.1% | Reduced |
| TB Alternative Assets Ltd. | 1,133 | $450.5K | 0.07% | 00.0% | Unchanged |
| Flow Traders U.S. LLC | 1,135 | $451.0K | 0.01% | +1,135 | New |
| Sagespring Wealth Partners, LLC | 1,136 | $451.8K | 0.01% | −151−11.7% | Reduced |
| Hilltop Holdings Inc. | 1,139 | $452.9K | 0.03% | −50−4.2% | Reduced |
| Lecap Asset Management Ltd | 1,151 | $457.7K | 0.18% | −267−18.8% | Reduced |
| Mathes Company, Inc. | 1,155 | $459.0K | 0.16% | 00.0% | Unchanged |
| Caerus Investment Advisors, LLC | 1,173 | $466.4K | 0.16% | −499−29.8% | Reduced |
| Wedmont Private Capital | 1,113 | $470.2K | 0.02% | +58+5.5% | Added |
| Norden Group LLC | 1,190 | $473.2K | 0.05% | −221−15.7% | Reduced |
| Smartleaf Asset Management LLC | 1,203 | $477.9K | 0.02% | +126+11.7% | Added |
| Bridges Investment Management Inc | 1,216 | $483.5K | 0.01% | +422+53.1% | Added |
| Cigna Investments Inc | 1,230 | $490.0K | 0.07% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 1,235 | $491.0K | 0.01% | +507+69.6% | Added |
| Pinnacle Financial Partners, Inc. | 1,237 | $491.9K | 0.00% | +1,237 | New |
| Frank, Rimerman Advisors LLC | 1,250 | $497.1K | 0.03% | −1−0.1% | Reduced |
| Winslow Capital Management, LLC | 1,266 | $503.4K | 0.00% | −69−5.2% | Reduced |
| Crossmark Global Holdings, Inc. | 1,281 | $509.4K | 0.01% | +57+4.7% | Added |
| S-Bank Fund Management Ltd | 1,281 | $509.4K | 0.07% | −312−19.6% | Reduced |
| Sava Infond d.o.o. | 1,285 | $511.0K | 0.07% | −355−21.6% | Reduced |
| AlphaCentric Advisors LLC | 1,295 | $515.0K | 0.51% | +1,295 | New |
| Wealthcare Advisory Partners LLC | 1,311 | $521.3K | 0.01% | +1,311 | New |
| PSP Research LLC | 1,318 | $524.1K | 0.46% | +1,318 | New |
| Headlands Technologies LLC | 1,345 | $534.8K | 0.04% | −8,847−86.8% | Reduced |
| Allworth Financial LP | 1,353 | $538.1K | 0.00% | +63+4.9% | Added |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,533 | $543.8K | 0.00% | 00.0% | Unchanged |
| Altfest L J & Co Inc | 1,378 | $548.0K | 0.06% | +1,378 | New |
| Souders Financial Advisors | 1,410 | $560.7K | 0.06% | −13−0.9% | Reduced |
| Steward Partners Investment Advisory, LLC | 1,425 | $566.7K | 0.00% | −18−1.2% | Reduced |
| Fulton Bank, N.A. | 1,430 | $568.6K | 0.02% | −114−7.4% | Reduced |
| Persistent Asset Partners Ltd | 1,433 | $569.8K | 0.27% | −819−36.4% | Reduced |
| Krilogy Financial LLC | 1,587 | $573.5K | 0.02% | −2,235−58.5% | Reduced |
| 111 Capital | 1,451 | $577.0K | 0.13% | +1,451 | New |
| Summit Financial, LLC | 1,456 | $579.0K | 0.01% | +1,456 | New |
| Qtron Investments LLC | 1,471 | $584.9K | 0.08% | 00.0% | Unchanged |
| Steel Peak Wealth Management LLC | 1,484 | $590.0K | 0.02% | −151−9.2% | Reduced |
| Yousif Capital Management, LLC | 1,676 | $595.9K | 0.01% | +29+1.8% | Added |
| High Net Worth Advisory Group LLC | 1,500 | $596.5K | 0.14% | 00.0% | Unchanged |
| Vise Technologies, Inc. | 1,515 | $602.4K | 0.01% | +491+47.9% | Added |
| EntryPoint Capital, LLC | 1,527 | $607.2K | 0.24% | +469+44.3% | Added |
| Orser Capital Management, LLC | 1,539 | $612.0K | 0.37% | −5−0.3% | Reduced |
| Forum Financial Management, LP | 1,546 | $614.8K | 0.01% | −10−0.6% | Reduced |
| Diversified Trust Co | 1,548 | $615.6K | 0.01% | −22−1.4% | Reduced |
| Coldstream Capital Management Inc | 1,574 | $625.9K | 0.01% | −66−4.0% | Reduced |
| Emerald Advisers, LLC | 1,622 | $645.0K | 0.02% | −73−4.3% | Reduced |
| J.Safra Asset Management Corp | 1,639 | $651.7K | 0.03% | +244+17.5% | Added |
| Fort Sheridan Advisors LLC | 1,701 | $676.4K | 0.09% | 00.0% | Unchanged |
| HB Wealth Management, LLC | 1,701 | $676.7K | 0.00% | +225+15.2% | Added |
| Virtus Investment Advisers, Inc. | 1,717 | $682.8K | 0.19% | +258+17.7% | Added |
| Ballentine Partners, LLC | 1,721 | $684.4K | 0.01% | +60+3.6% | Added |
| NorthCrest Asset Manangement, LLC | 1,733 | $689.4K | 0.02% | +128+8.0% | Added |
| New York Life Investment Management LLC | 1,745 | $693.9K | 0.01% | +116+7.1% | Added |
| Sara-Bay Financial | 1,750 | $695.2K | 0.21% | +300+20.7% | Added |
| Woodline Partners LP | 1,759 | $699.5K | 0.00% | −90,032−98.1% | Reduced |
| Davenport & Co LLC | 1,759 | $699.5K | 0.00% | +1,759 | New |
| Evolve Private Wealth, LLC | 1,783 | $709.0K | 0.04% | +1,783 | New |
| GraniteShares Advisors LLC | 1,786 | $710.2K | 0.43% | +147+9.0% | Added |
| Ossiam | 1,786 | $710.2K | 0.01% | +230+14.8% | Added |
| Siemens Fonds Invest GmbH | 1,837 | $729.7K | 0.04% | 00.0% | Unchanged |
| Meeder Advisory Services, Inc. | 1,838 | $730.9K | 0.03% | −51−2.7% | Reduced |
| Kestra Advisory Services, LLC | 1,851 | $736.0K | 0.00% | +206+12.5% | Added |
| XTX Topco Ltd | 1,856 | $738.0K | 0.02% | +1,022+122.5% | Added |
| Global Retirement Partners, LLC | 1,856 | $738.0K | 0.01% | +1,407+313.4% | Added |
| AlphaGrep UK Ltd | 1,856 | $738.0K | 0.25% | +1,856 | New |
| Quest Partners LLC | 1,881 | $748.0K | 0.04% | +1,550+468.3% | Added |
| Bannerman Wealth Management Group, LLC | 1,947 | $774.2K | 0.55% | −100−4.9% | Reduced |
| Kovitz Investment Group Partners, LLC | 1,955 | $777.6K | 0.02% | −652−25.0% | Reduced |
| V-Square Quantitative Management LLC | 1,958 | $778.6K | 0.08% | +1,958 | New |
| Signaturefd, LLC | 1,981 | $787.9K | 0.01% | −17−0.9% | Reduced |
| Tema ETFs LLC | 1,996 | $793.7K | 0.06% | −567−22.1% | Reduced |