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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
852
+55 vs. Q3 2025
Shares held
132.8M
+3.06M (+2.4%) vs. Q3 2025
Total value
$52.7B
−$6.43B (−10.9%) vs. Q3 2025
New holders
172
290 more added
Sold out
117
291 more reduced

26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 852 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2025: $52.7B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ALNY in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rothschild Investment LLC360$143.2K0.01%−718−66.6%Reduced
SageView Advisory Group, LLC398$158.3K0.01%+398New
Bayforest Capital Ltd412$163.8K0.12%+412New
Versant Capital Management, Inc416$165.4K0.02%+24+6.1%Added
USA Financial Portformulas Corp424$168.6K0.03%+424New
Essential Partners LLC445$177.0K0.05%−791−64.0%Reduced
MAI Capital Management447$177.9K0.00%−2−0.4%Reduced
Horizon Investments, LLC451$179.3K0.00%+48+11.9%Added
Perkins Coie Trust Co500$198.8K0.04%+500New
Align Financial, LLC198,825$198.8K0.12%+198,825New
PharVision Advisers, LLC504$200.4K0.10%+504New
Resources Investment Advisors, LLC.510$202.7K0.00%−220−30.1%Reduced
Fortitude Family Office, LLC517$205.6K0.05%00.0%Unchanged
Cascade Financial Partners, LLC523$207.9K0.02%−104−16.6%Reduced
GTS Securities LLC525$208.8K0.01%+525New
Ariadne Wealth Management, LP677$208.8K0.09%−26−3.7%Reduced
AlphaCore Capital LLC527$209.6K0.00%+527New
Soltis Investment Advisors LLC530$210.6K0.01%+530New
Towarzystwo Funduszy Inwestycyjnych Pzu SA530$210.8K0.05%00.0%Unchanged
Intrust Bank NA538$213.9K0.02%+538New
Fi3 FINANCIAL ADVISORS, LLC539$214.3K0.07%−2−0.4%Reduced
Capital Performance Advisors LLP541$215.1K0.02%−47−8.0%Reduced
Portside Wealth Group, LLC546$217.1K0.03%−205−27.3%Reduced
Essex LLC546$217.1K0.04%−1−0.2%Reduced
Gabelli Funds LLC550$218.7K0.00%+550New
Chicago Partners Investment Group LLC617$220.9K0.01%−355−36.5%Reduced
Alta Advisers Ltd557$221.5K0.08%−200−26.4%Reduced
Fidelis Capital Partners, LLC563$223.9K0.02%+24+4.5%Added
Oversea-Chinese Banking CORP Ltd565$224.7K0.01%+565New
Northwest Wealth Management, LLC565$224.7K0.04%+565New
Kingswood Wealth Advisors, LLC574$228.3K0.01%+574New
Cooper Financial Group580$230.6K0.02%−17−2.8%Reduced
Algert Global LLC580$230.6K0.00%+580New
Northwestern Mutual Wealth Management Co581$231.0K0.00%+14+2.5%Added
LVW Advisors, LLC582$231.4K0.02%−8−1.4%Reduced
Graham Capital Management, L.P.588$233.8K0.01%−2,427−80.5%Reduced
Premier Path Wealth Partners, LLC596$236.8K0.03%+92+18.3%Added
Evercore Wealth Management, LLC600$238.6K0.00%00.0%Unchanged
AlTi Global, Inc.602$239.4K0.01%+26+4.5%Added
Covenant Partners, LLC604$240.2K0.07%00.0%Unchanged
LeConte Wealth Management, LLC604$240.2K0.16%+78+14.8%Added
PCM Encore, LLC605$240.4K0.05%+605New
Independent Advisor Alliance605$240.6K0.01%−74−10.9%Reduced
Waterloo Capital, L.P.605$240.6K0.02%−25−4.0%Reduced
Quadrant Capital Group LLC615$244.6K0.01%+62+11.2%Added
Transcend Wealth Collective, LLC620$246.5K0.02%−279−31.0%Reduced
Everpar Advisors LLC620$246.5K0.09%+37+6.3%Added
Evoke Wealth, LLC621$246.9K0.00%−275−30.7%Reduced
Journey Retirement Planning & Investment Management LLC630$250.5K0.05%+630New
Plante Moran Financial Advisors, LLC635$252.5K0.02%−2−0.3%Reduced
Sowell Financial Services LLC645$256.5K0.01%−9−1.4%Reduced
West Family Investments, Inc.646$256.9K0.06%−176−21.4%Reduced
Skopos Labs, Inc.648$258.3K0.01%+648New
IFP Advisors, Inc664$264.0K0.01%+173+35.2%Added
Legacy Wealth Asset Management, LLC668$265.6K0.07%−26−3.7%Reduced
L2 Asset Management, LLC671$266.8K0.04%+60+9.8%Added
EP Wealth Advisors, LLC671$266.8K0.00%+671New
Savvy Advisors, Inc.672$267.2K0.01%−38−5.4%Reduced
Glenmede Trust Co NA675$268.4K0.00%+675New
Scientech Research LLC676$268.8K0.17%−3,196−82.5%Reduced
SRS Capital Advisors, Inc.678$269.6K0.01%−12,407−94.8%Reduced
Fiduciary Trust Co680$270.5K0.00%+7+1.0%Added
Ashton Thomas Securities, LLC688$273.6K0.05%+688New
Dynasty Wealth Management, LLC688$273.6K0.00%+20+3.0%Added
Essex Financial Services, Inc.690$274.2K0.02%−24−3.4%Reduced
GenTrust, LLC695$276.4K0.01%+695New
Independent Financial Group, LLC698$277.6K0.01%+66+10.4%Added
Bradley Foster & Sargent Inc701$278.8K0.00%+81+13.1%Added
Ofi Invest Asset Management776$281.4K0.00%+373+92.6%Added
Perfromance Wealth Partners, LLC725$288.3K0.01%00.0%Unchanged
Meridian Financial, LLC728$289.5K0.16%−100−12.1%Reduced
Sym Financial Corp729$289.9K0.03%+54+8.0%Added
Banco Santander, S.A.731$290.7K0.00%+731New
Benjamin Edwards Inc733$291.4K0.00%+246+50.5%Added
Kaufman Rossin Wealth, LLC749$297.7K0.16%+266+55.1%Added
SkyOak Wealth, LLC760$302.2K0.05%−87−10.3%Reduced
Wick Capital Partners, LLC769$305.8K0.05%+769New
Perigon Wealth Management, LLC776$308.6K0.01%−407−34.4%Reduced
Jones Financial Companies LLLP780$310.2K0.00%+238+43.9%Added
Lido Advisors, LLC717$311.9K0.00%+59+9.0%Added
Beacon Pointe Advisors, LLC790$314.1K0.00%−164−17.2%Reduced
Blueshift Asset Management, LLC791$314.5K0.09%+188+31.2%Added
Ascent Group, LLC795$316.1K0.01%+171+27.4%Added
Concurrent Investment Advisors, LLC802$318.9K0.00%+802New
Cookson Peirce & Co Inc811$322.5K0.01%+264+48.3%Added
Chapin Davis, Inc.825$328.1K0.08%00.0%Unchanged
Parallel Advisors, LLC826$328.5K0.01%+30+3.8%Added
Nwam LLC914$330.3K0.02%+2+0.2%Added
HighPoint Advisor Group LLC832$330.8K0.01%+128+18.2%Added
We Are One Seven, LLC833$331.2K0.01%+133+19.0%Added
Snowden Capital Advisors LLC834$331.6K0.01%−33−3.8%Reduced
Warren Averett Asset Management, LLC840$334.0K0.00%−25−2.9%Reduced
Stephens Inc845$336.0K0.00%+146+20.9%Added
Poinciana Advisors Group, LLC851$338.4K0.27%−6−0.7%Reduced
Jackson Thornton Asset Management, LLC842$342.2K0.03%−76−8.3%Reduced
Ellevest, Inc.863$343.2K0.05%+89+11.5%Added
Savant Capital, LLC875$347.9K0.00%−8−0.9%Reduced
Beese Fulmer Investment Management, Inc.888$353.1K0.02%+888New
GAMMA Investing LLC893$355.1K0.02%+70+8.5%Added
waypoint wealth counsel895$355.9K0.13%+274+44.1%Added