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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covenant Partners, LLC604$275.4K0.08%+604New
Blueshift Asset Management, LLC603$275.0K0.08%+603New
Consolidated Portfolio Review Corp601$274.1K0.03%+601New
Humankind Investments LLC600$273.6K0.06%−296−33.0%Reduced
Evercore Wealth Management, LLC600$273.6K0.00%+600New
Point72 Hong Kong Ltd598$272.7K0.01%+598New
Cooper Financial Group597$272.2K0.03%+597New
LVW Advisors, LLC590$269.0K0.03%+590New
Capital Performance Advisors LLP588$268.1K0.04%+588New
Beacon Investment Advisory Services, Inc.585$266.8K0.01%−705−54.7%Reduced
Charter Research & Investment Group, Inc.585$266.8K0.18%+585New
Everpar Advisors LLC583$265.8K0.11%+583New
AlTi Global, Inc.576$262.7K0.01%+576New
Private Trust Co NA575$262.2K0.02%+543+1,696.9%Added
Fourth Dimension Wealth, LLC573$261.3K0.10%−16−2.7%Reduced
Northwestern Mutual Wealth Management Co567$258.6K0.00%+71+14.3%Added
Stevens Capital Management LP565$258.0K0.03%+565New
Quadrant Capital Group LLC553$252.2K0.01%+553New
Fukoku Mutual Life Insurance Co551$251.3K0.02%−108−16.4%Reduced
Essex LLC547$249.4K0.05%−241−30.6%Reduced
Cookson Peirce & Co Inc547$249.4K0.01%+547New
First Affirmative Financial Network542$247.0K0.12%+542New
Fi3 FINANCIAL ADVISORS, LLC541$246.7K0.08%+541New
Capital International Investors550$246.3K0.00%+550New
Fidelis Capital Partners, LLC539$245.8K0.02%+3+0.6%Added
Stonegate Investment Group, LLC535$244.1K0.01%−149−21.8%Reduced
Armis Advisers, LLC560$243.1K0.02%+560New
Fiduciary Alliance LLC533$243.0K0.02%+533New
Jones Financial Companies LLLP542$242.0K0.00%−30−5.2%Reduced
Towarzystwo Funduszy Inwestycyjnych Pzu SA530$241.7K0.06%−572−51.9%Reduced
LeConte Wealth Management, LLC526$239.9K0.16%+526New
Fortitude Family Office, LLC517$235.8K0.06%00.0%Unchanged
Kestra Private Wealth Services, LLC504$229.8K0.00%+504New
Alliance Wealth Advisors, LLC504$229.8K0.05%+504New
Premier Path Wealth Partners, LLC504$229.6K0.03%+504New
Gries Financial LLC502$228.9K0.04%+502New
Headinvest, LLC500$228.0K0.05%+500New
Longboard Asset Management, LP500$228.0K0.37%+500New
NWF Advisory Services Inc.498$226.9K0.02%+498New
TABR Capital Management, LLC504$225.5K0.15%+504New
MASTERINVEST Kapitalanlage GmbH494$225.3K0.02%+494New
IFP Advisors, Inc491$223.9K0.01%+291+145.5%Added
Proficio Capital Partners LLC488$222.5K0.02%−394−44.7%Reduced
Benjamin Edwards Inc487$222.1K0.00%+487New
Glenmede Investment Management, LP485$221.2K0.00%+485New
Telos Capital Management, Inc.483$220.2K0.02%+483New
Reuter James Wealth Management, LLC483$220.2K0.03%+483New
Kaufman Rossin Wealth, LLC483$220.1K0.12%+483New
Gsa Capital Partners LLP476$217.0K0.02%+476New
Arvest Bank Trust Division472$215.2K0.01%+472New
Riversedge Advisors, LLC471$214.8K0.04%+471New
Camden Capital, LLC468$213.3K0.01%+468New
Allegiance Financial Group Advisory Services LLC462$210.7K0.05%+462New
Advisor OS, LLC461$210.2K0.02%+461New
Dorsey & Whitney Trust CO LLC460$209.8K0.01%+460New
Bank Hapoalim BM455$207.0K0.03%+455New
KRS Capital Management, LLC450$205.2K0.12%+450New
Global Retirement Partners, LLC449$204.7K0.00%+298+197.4%Added
Insigneo Advisory Services, LLC449$204.7K0.01%+449New
MAI Capital Management449$204.7K0.00%−39−8.0%Reduced
Ritholtz Wealth Management447$203.7K0.00%+447New
Summit Wealth Group LLC643$202.0K0.03%+643New
Point72 (DIFC) Ltd429$195.5K0.01%+324+308.6%Added
Icon Wealth Advisors, LLC422$192.4K0.01%+36+9.3%Added
Horizon Investments, LLC403$183.8K0.00%+63+18.5%Added
Versant Capital Management, Inc392$178.8K0.02%+5+1.3%Added
Ostrum Asset Management381$173.7K0.01%−13−3.3%Reduced
CoreCap Advisors, LLC380$173.3K0.01%+378+18,900.0%Added
Ronald Blue Trust, Inc.349$159.1K0.00%−944−73.0%Reduced
Ofi Invest Asset Management403$156.4K0.00%+22+5.8%Added
TD Waterhouse Canada Inc.330$152.1K0.00%+300+1,000.0%Added
Quest Partners LLC331$150.9K0.01%+199+150.8%Added
Larson Financial Group LLC300$136.8K0.00%+78+35.1%Added
Covestor Ltd272$124.0K0.07%−69−20.2%Reduced
True Wealth Design, LLC228$103.9K0.03%+214+1,528.6%Added
Bessemer Group Inc222$101.0K0.00%+30+15.6%Added
Spire Wealth Management207$94.3K0.00%+2+1.0%Added
Concord Wealth Partners200$91.2K0.01%00.0%Unchanged
Massmutual Trust Co FSB197$89.8K0.00%+1+0.5%Added
Atlantic Union Bankshares Corp191$87.1K0.00%+99+107.6%Added
LRI Investments, LLC190$86.5K0.01%+142+295.8%Added
Edmond de Rothschild Holding S.A.188$85.7K0.00%00.0%Unchanged
Stephenson National Bank & Trust185$84.4K0.03%00.0%Unchanged
Prestige Wealth Management Group LLC184$83.9K0.02%00.0%Unchanged
Parkside Financial Bank & Trust179$81.6K0.01%00.0%Unchanged
Evelyn Partners Investment Management LLP175$79.8K0.00%−75−30.0%Reduced
Brown Brothers Harriman & Co173$78.9K0.00%+19+12.3%Added
Itau Unibanco Holding S.A.168$76.6K0.00%00.0%Unchanged
Capital Advisors, Ltd. LLC162$74.0K0.01%00.0%Unchanged
Abich Financial Wealth Management LLC147$67.0K0.02%+147New
First Horizon Corp135$61.6K0.00%+135New
Brown, Lisle/Cummings, Inc.132$60.2K0.02%00.0%Unchanged
Harbour Investments, Inc.127$57.9K0.00%+31+32.3%Added
Park Place Capital Corp126$57.5K0.01%+126New
Cornerstone Planning Group LLC492$56.2K0.01%+450+1,071.4%Added
Ameritas Advisory Services, LLC116$52.9K0.00%−12−9.4%Reduced
Whittier Trust Co of Nevada Inc115$52.5K0.00%+63+121.2%Added
Rossby Financial, LCC112$51.6K0.02%+63+128.6%Added
Cape Investment Advisory, Inc.108$49.2K0.05%+8+8.0%Added
Huntington National Bank101$46.1K0.00%−94−48.2%Reduced