Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 823
- +178 vs. Q2 2025
- Shares held
- 129.9M
- −193.8K (−0.1%) vs. Q2 2025
- Total value
- $59.2B
- +$16.8B (+39.6%) vs. Q2 2025
- New holders
- 225
- 283 more added
- Sold out
- 47
- 223 more reduced
8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State of Wisconsin Investment Board | 68,529 | $31.2M | 0.07% | −9,577−12.3% | Reduced |
| Asset Management One Co.,Ltd. | 69,610 | $31.7M | 0.09% | +300+0.4% | Added |
| Man Group plc | 71,673 | $32.7M | 0.06% | +63,564+783.9% | Added |
| Storebrand Asset Management AS | 72,017 | $32.8M | 0.09% | +27,696+62.5% | Added |
| HSBC Holdings PLC | 73,014 | $33.3M | 0.02% | −8,734−10.7% | Reduced |
| Rock Springs Capital Management LP | 74,250 | $33.9M | 1.98% | −25,750−25.8% | Reduced |
| Capital International Inc | 75,638 | $34.5M | 0.28% | +3,807+5.3% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 77,461 | $35.3M | 0.08% | −8,273−9.6% | Reduced |
| Jain Global LLC | 78,046 | $35.6M | 0.46% | +61,316+366.5% | Added |
| Capital International Ltd | 78,223 | $35.7M | 1.29% | −4,577−5.5% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 79,652 | $36.3M | 0.15% | −5,236−6.2% | Reduced |
| Assenagon Asset Management S.A. | 80,381 | $36.7M | 0.05% | +62,695+354.5% | Added |
| Aquatic Capital Management LLC | 84,059 | $38.3M | 0.71% | +84,059 | New |
| Parkman Healthcare Partners LLC | 87,690 | $40.0M | 4.39% | −4,648−5.0% | Reduced |
| Westfield Capital Management Co LP | 87,908 | $40.1M | 0.17% | −98,997−53.0% | Reduced |
| Nomura Asset Management Co Ltd | 89,869 | $41.0M | 0.11% | −1,505−1.6% | Reduced |
| Great West Life Assurance Co | 93,092 | $41.6M | 0.06% | +1,938+2.1% | Added |
| Woodline Partners LP | 91,791 | $41.9M | 0.20% | −531,324−85.3% | Reduced |
| Barclays PLC | 94,408 | $43.1M | 0.02% | +350+0.4% | Added |
| SEI Investments Co | 94,481 | $43.1M | 0.05% | −214,138−69.4% | Reduced |
| Eventide Asset Management, LLC | 101,739 | $46.4M | 0.76% | −24,163−19.2% | Reduced |
| Aviva PLC | 103,206 | $47.1M | 0.09% | +6,141+6.3% | Added |
| Allianz Asset Management GmbH | 106,816 | $48.7M | 0.06% | −99,177−48.1% | Reduced |
| DekaBank Deutsche Girozentrale | 113,193 | $50.3M | 0.08% | 00.0% | Unchanged |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 110,552 | $50.4M | 0.08% | −3,814−3.3% | Reduced |
| HighTower Advisors, LLC | 110,624 | $50.4M | 0.06% | +1,359+1.2% | Added |
| Robeco Institutional Asset Management B.V. | 113,074 | $51.6M | 0.07% | +16,706+17.3% | Added |
| State Board of Administration of Florida Retirement System | 117,226 | $53.5M | 0.09% | −9,824−7.7% | Reduced |
| Congress Asset Management Co | 118,800 | $54.2M | 0.36% | +118,800 | New |
| Frontier Capital Management Co LLC | 118,878 | $54.2M | 0.49% | +15,875+15.4% | Added |
| Envestnet Asset Management Inc | 118,964 | $54.2M | 0.02% | +23,168+24.2% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 120,787 | $55.1M | 0.04% | +9,002+8.1% | Added |
| Capital International Sarl | 129,702 | $59.1M | 1.02% | +1,416+1.1% | Added |
| Neuberger Berman Group LLC | 130,544 | $59.5M | 0.04% | +31,500+31.8% | Added |
| FIL Ltd | 135,484 | $61.8M | 0.05% | −12,453−8.4% | Reduced |
| Janus Henderson Group PLC | 135,855 | $61.9M | 0.03% | −14,566−9.7% | Reduced |
| Canada Pension Plan Investment Board | 136,331 | $62.2M | 0.04% | +100,811+283.8% | Added |
| Squarepoint Ops LLC | 145,565 | $66.4M | 0.14% | +143,119+5,851.1% | Added |
| SCS Capital Management LLC | 150,668 | $68.7M | 0.75% | −19,994−11.7% | Reduced |
| BNP Paribas Arbitrage, SA | 153,039 | $69.8M | 0.05% | +24,405+19.0% | Added |
| Handelsbanken Fonder AB | 155,369 | $70.8M | 0.23% | +70.0% | Added |
| Standard Life Aberdeen plc | 157,396 | $71.7M | 0.11% | −61,228−28.0% | Reduced |
| Los Angeles Capital Management LLC | 159,394 | $72.7M | 0.25% | +91,995+136.5% | Added |
| National Pension Service | 177,238 | $80.8M | 0.06% | +2,192+1.3% | Added |
| Victory Capital Management Inc | 180,349 | $82.2M | 0.05% | +24,055+15.4% | Added |
| Russell Investments Group, Ltd. | 195,916 | $89.2M | 0.10% | +102,481+109.7% | Added |
| Rhumbline Advisers | 196,497 | $89.6M | 0.07% | −3,988−2.0% | Reduced |
| Korea Investment CORP | 196,912 | $89.8M | 0.18% | +86,057+77.6% | Added |
| D. E. Shaw & Co., Inc. | 199,417 | $90.9M | 0.07% | +91,141+84.2% | Added |
| California State Teachers Retirement System | 203,778 | $92.9M | 0.10% | +4,462+2.2% | Added |
| First Trust Advisors LP | 210,383 | $95.9M | 0.07% | −41,434−16.5% | Reduced |
| Candriam Luxembourg S.C.A. | 212,416 | $96.9M | 0.51% | −25,668−10.8% | Reduced |
| CIBC Private Wealth Group, LLC | 214,213 | $97.7M | 0.17% | −4,116−1.9% | Reduced |
| Worldquant Millennium Advisors LLC | 220,634 | $100.6M | 0.43% | +103,261+88.0% | Added |
| Citadel Advisors LLC | 221,843 | $101.2M | 0.08% | −379,356−63.1% | Reduced |
| Ameriprise Financial Inc | 225,879 | $103.0M | 0.02% | +32,230+16.6% | Added |
| California Public Employees Retirement System | 229,641 | $104.7M | 0.06% | +18,060+8.5% | Added |
| Dimensional Fund Advisors LP | 241,934 | $110.3M | 0.02% | −63,629−20.8% | Reduced |
| Polar Capital Holdings Plc | 251,460 | $114.7M | 0.55% | +13,960+5.9% | Added |
| Royal London Asset Management Ltd | 257,313 | $117.3M | 0.25% | −1,758−0.7% | Reduced |
| KBC Group NV | 273,352 | $124.6M | 0.30% | +79,802+41.2% | Added |
| Wells Fargo & Company | 280,568 | $127.9M | 0.03% | −41,256−12.8% | Reduced |
| Susquehanna Advisors Group, Inc. | 286,100 | $130.5M | 4.02% | +286,100 | New |
| HRT Financial LP | 291,449 | $132.9M | 0.49% | +273,562+1,529.4% | Added |
| OrbiMed Advisors LLC | 301,600 | $137.5M | 3.30% | −40,300−11.8% | Reduced |
| Jennison Associates LLC | 304,863 | $139.0M | 0.08% | −45,207−12.9% | Reduced |
| TD Asset Management Inc | 312,517 | $142.5M | 0.12% | −128,660−29.2% | Reduced |
| Allspring Global Investments Holdings, LLC | 310,804 | $143.2M | 0.23% | −1,412−0.5% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 314,452 | $143.4M | 0.08% | +20,910+7.1% | Added |
| Gilder Gagnon Howe & Co LLC | 329,321 | $150.2M | 1.53% | −7,767−2.3% | Reduced |
| Massachusetts Financial Services Co | 356,529 | $162.6M | 0.05% | +356,529 | New |
| Voloridge Investment Management, LLC | 356,806 | $162.7M | 0.55% | +349,104+4,532.6% | Added |
| Voya Investment Management LLC | 373,356 | $170.3M | 0.17% | +162,311+76.9% | Added |
| Swiss National Bank | 375,800 | $171.4M | 0.10% | −18,000−4.6% | Reduced |
| Raymond James Financial Inc | 377,294 | $172.0M | 0.06% | +106,844+39.5% | Added |
| Amundi | 384,272 | $173.7M | 0.06% | −9,907−2.5% | Reduced |
| Pictet Asset Management Holding SA | 387,546 | $176.0M | 0.17% | −77,060−16.6% | Reduced |
| Jacobs Levy Equity Management, Inc | 410,342 | $187.1M | 0.74% | +392,668+2,221.7% | Added |
| Bank of New York Mellon Corp | 419,783 | $191.4M | 0.03% | −9,986−2.3% | Reduced |
| Royal Bank of Canada | 436,758 | $199.2M | 0.04% | +5,923+1.4% | Added |
| Bellevue Group AG | 446,524 | $203.6M | 4.23% | −229,843−34.0% | Reduced |
| 1832 Asset Management L.P. | 459,345 | $209.5M | 0.35% | +236,000+105.7% | Added |
| UBS Group AG | 488,204 | $222.6M | 0.04% | −55,282−10.2% | Reduced |
| Loomis Sayles & Co L P | 500,672 | $228.3M | 0.27% | +13,344+2.7% | Added |
| Marshall Wace, LLP | 508,371 | $231.8M | 0.25% | +269,798+113.1% | Added |
| Goldman Sachs Group Inc | 538,346 | $245.5M | 0.04% | −6,970−1.3% | Reduced |
| Millennium Management LLC | 549,931 | $250.8M | 0.20% | +459,486+508.0% | Added |
| Federated Hermes, Inc. | 550,104 | $250.8M | 0.44% | +226,262+69.9% | Added |
| Susquehanna International Group, LLP | 577,632 | $263.4M | 0.39% | +369,370+177.4% | Added |
| Nuveen, LLC | 587,821 | $268.0M | 0.07% | −187,148−24.1% | Reduced |
| Two Sigma Investments, LP | 595,926 | $271.7M | 0.42% | +252,621+73.6% | Added |
| Deutsche Bank AG | 606,320 | $276.5M | 0.09% | −42,964−6.6% | Reduced |
| Charles Schwab Investment Management Inc | 618,770 | $282.2M | 0.05% | +47,023+8.2% | Added |
| Clearbridge Investments, LLC | 622,435 | $283.8M | 0.21% | +65,336+11.7% | Added |
| Macquarie Group Ltd | 648,344 | $295.6M | 0.35% | +48,233+8.0% | Added |
| UBS Asset Management Americas Inc | 708,564 | $323.1M | 0.07% | −249,772−26.1% | Reduced |
| Franklin Resources Inc | 714,012 | $325.6M | 0.08% | +112,681+18.7% | Added |
| Morgan Stanley | 726,061 | $331.1M | 0.02% | −44,907−5.8% | Reduced |
| AQR Capital Management LLC | 744,008 | $336.0M | 0.22% | +555,759+295.2% | Added |
| Qube Research & Technologies Ltd | 811,278 | $369.9M | 0.52% | +811,278 | New |