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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Root Financial Partners, LLC54$24.6K0.00%+54New
Fifth Third Bancorp57$26.0K0.00%−19−25.0%Reduced
Truvestments Capital LLC57$26.1K0.00%00.0%Unchanged
Global Trust Asset Management, LLC60$27.4K0.01%00.0%Unchanged
Salomon & Ludwin, LLC60$27.4K0.00%+60New
Private Wealth Management Group, LLC62$28.3K0.01%00.0%Unchanged
CVA Family Office, LLC62$28.3K0.00%+1+1.6%Added
SBI Securities Co., Ltd.63$28.7K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd63$28.7K0.02%+63New
MV Capital Management, Inc.64$29.2K0.00%+1+1.6%Added
Whittier Trust Co69$31.5K0.00%00.0%Unchanged
Ameriflex Group, Inc.70$31.9K0.01%+70New
Sachetta, LLC73$33.3K0.01%00.0%Unchanged
TFC Financial Management74$33.7K0.00%00.0%Unchanged
Transamerica Financial Advisors, Inc.77$35.1K0.00%+77New
Aster Capital Management (DIFC) Ltd78$35.6K0.02%+78New
ORG Partners LLC80$36.5K0.01%+33+70.2%Added
Quent Capital, LLC85$38.8K0.00%+85New
Newbridge Financial Services Group, Inc.85$38.9K0.01%+85New
Hemington Wealth Management88$40.0K0.01%+1+1.1%Added
Hilltop National Bank91$41.5K0.01%+91New
Westside Investment Management, Inc.96$44.2K0.01%+48+100.0%Added
Hartford Financial Management Inc.100$45.6K0.01%00.0%Unchanged
Huntington National Bank101$46.1K0.00%−94−48.2%Reduced
Cape Investment Advisory, Inc.108$49.2K0.05%+8+8.0%Added
Rossby Financial, LCC112$51.6K0.02%+63+128.6%Added
Whittier Trust Co of Nevada Inc115$52.5K0.00%+63+121.2%Added
Ameritas Advisory Services, LLC116$52.9K0.00%−12−9.4%Reduced
Cornerstone Planning Group LLC492$56.2K0.01%+450+1,071.4%Added
Park Place Capital Corp126$57.5K0.01%+126New
Harbour Investments, Inc.127$57.9K0.00%+31+32.3%Added
Brown, Lisle/Cummings, Inc.132$60.2K0.02%00.0%Unchanged
First Horizon Corp135$61.6K0.00%+135New
Abich Financial Wealth Management LLC147$67.0K0.02%+147New
Capital Advisors, Ltd. LLC162$74.0K0.01%00.0%Unchanged
Itau Unibanco Holding S.A.168$76.6K0.00%00.0%Unchanged
Brown Brothers Harriman & Co173$78.9K0.00%+19+12.3%Added
Evelyn Partners Investment Management LLP175$79.8K0.00%−75−30.0%Reduced
Parkside Financial Bank & Trust179$81.6K0.01%00.0%Unchanged
Prestige Wealth Management Group LLC184$83.9K0.02%00.0%Unchanged
Stephenson National Bank & Trust185$84.4K0.03%00.0%Unchanged
Edmond de Rothschild Holding S.A.188$85.7K0.00%00.0%Unchanged
LRI Investments, LLC190$86.5K0.01%+142+295.8%Added
Atlantic Union Bankshares Corp191$87.1K0.00%+99+107.6%Added
Massmutual Trust Co FSB197$89.8K0.00%+1+0.5%Added
Concord Wealth Partners200$91.2K0.01%00.0%Unchanged
Spire Wealth Management207$94.3K0.00%+2+1.0%Added
Bessemer Group Inc222$101.0K0.00%+30+15.6%Added
True Wealth Design, LLC228$103.9K0.03%+214+1,528.6%Added
Covestor Ltd272$124.0K0.07%−69−20.2%Reduced
Larson Financial Group LLC300$136.8K0.00%+78+35.1%Added
Quest Partners LLC331$150.9K0.01%+199+150.8%Added
TD Waterhouse Canada Inc.330$152.1K0.00%+300+1,000.0%Added
Ofi Invest Asset Management403$156.4K0.00%+22+5.8%Added
Ronald Blue Trust, Inc.349$159.1K0.00%−944−73.0%Reduced
CoreCap Advisors, LLC380$173.3K0.01%+378+18,900.0%Added
Ostrum Asset Management381$173.7K0.01%−13−3.3%Reduced
Versant Capital Management, Inc392$178.8K0.02%+5+1.3%Added
Horizon Investments, LLC403$183.8K0.00%+63+18.5%Added
Icon Wealth Advisors, LLC422$192.4K0.01%+36+9.3%Added
Point72 (DIFC) Ltd429$195.5K0.01%+324+308.6%Added
Summit Wealth Group LLC643$202.0K0.03%+643New
Ritholtz Wealth Management447$203.7K0.00%+447New
MAI Capital Management449$204.7K0.00%−39−8.0%Reduced
Global Retirement Partners, LLC449$204.7K0.00%+298+197.4%Added
Insigneo Advisory Services, LLC449$204.7K0.01%+449New
KRS Capital Management, LLC450$205.2K0.12%+450New
Bank Hapoalim BM455$207.0K0.03%+455New
Dorsey & Whitney Trust CO LLC460$209.8K0.01%+460New
Advisor OS, LLC461$210.2K0.02%+461New
Allegiance Financial Group Advisory Services LLC462$210.7K0.05%+462New
Camden Capital, LLC468$213.3K0.01%+468New
Riversedge Advisors, LLC471$214.8K0.04%+471New
Arvest Bank Trust Division472$215.2K0.01%+472New
Gsa Capital Partners LLP476$217.0K0.02%+476New
Kaufman Rossin Wealth, LLC483$220.1K0.12%+483New
Telos Capital Management, Inc.483$220.2K0.02%+483New
Reuter James Wealth Management, LLC483$220.2K0.03%+483New
Glenmede Investment Management, LP485$221.2K0.00%+485New
Benjamin Edwards Inc487$222.1K0.00%+487New
Proficio Capital Partners LLC488$222.5K0.02%−394−44.7%Reduced
IFP Advisors, Inc491$223.9K0.01%+291+145.5%Added
MASTERINVEST Kapitalanlage GmbH494$225.3K0.02%+494New
TABR Capital Management, LLC504$225.5K0.15%+504New
NWF Advisory Services Inc.498$226.9K0.02%+498New
Headinvest, LLC500$228.0K0.05%+500New
Longboard Asset Management, LP500$228.0K0.37%+500New
Gries Financial LLC502$228.9K0.04%+502New
Premier Path Wealth Partners, LLC504$229.6K0.03%+504New
Kestra Private Wealth Services, LLC504$229.8K0.00%+504New
Alliance Wealth Advisors, LLC504$229.8K0.05%+504New
Fortitude Family Office, LLC517$235.8K0.06%00.0%Unchanged
LeConte Wealth Management, LLC526$239.9K0.16%+526New
Towarzystwo Funduszy Inwestycyjnych Pzu SA530$241.7K0.06%−572−51.9%Reduced
Jones Financial Companies LLLP542$242.0K0.00%−30−5.2%Reduced
Fiduciary Alliance LLC533$243.0K0.02%+533New
Armis Advisers, LLC560$243.1K0.02%+560New
Stonegate Investment Group, LLC535$244.1K0.01%−149−21.8%Reduced
Fidelis Capital Partners, LLC539$245.8K0.02%+3+0.6%Added
Capital International Investors550$246.3K0.00%+550New