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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
653
+35 vs. Q1 2025
Shares held
132.1M
+2.77M (+2.1%) vs. Q1 2025
Total value
$43.1B
+$8.27B (+23.8%) vs. Q1 2025
New holders
98
262 more added
Sold out
63
214 more reduced

7 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 653 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ2 2025: $43.1B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding ALNY in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
HRT Financial LP17,887$5.83M0.03%−37,286−67.6%Reduced
First Turn Management, LLC17,879$5.83M1.09%+17,879New
MML Investors Services, LLC17,838$5.82M0.02%+4,911+38.0%Added
Gotham Asset Management, LLC17,787$5.80M0.03%+3,270+22.5%Added
Capital Group Investment Management Pte. Ltd.17,738$5.78M1.03%+388+2.2%Added
Assenagon Asset Management S.A.17,686$5.77M0.01%+11,281+176.1%Added
Jacobs Levy Equity Management, Inc17,674$5.76M0.02%−135,296−88.4%Reduced
Jump Financial, LLC17,392$5.67M0.07%+1,675+10.7%Added
Jain Global LLC16,730$5.46M0.08%+10,509+168.9%Added
Nissay Asset Management Corp16,288$5.31M0.03%+74+0.5%Added
Mutual of America Capital Management LLC15,946$5.20M0.06%+2,302+16.9%Added
Creative Planning15,580$5.08M0.00%−519−3.2%Reduced
Hudson Bay Capital Management LP15,348$5.00M0.03%+15,348New
Mariner, LLC15,073$4.91M0.01%+190+1.3%Added
J. Safra Sarasin Holding AG14,996$4.89M0.08%−1,439−8.8%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd14,808$4.83M0.04%+1,851+14.3%Added
Elo Mutual Pension Insurance Co14,127$4.61M0.09%+3,222+29.5%Added
OP Asset Management Ltd13,934$4.54M0.07%+255+1.9%Added
Stifel Financial Corp13,700$4.47M0.00%+6,627+93.7%Added
Aware Super Pty Ltd as trustee of Aware Super13,665$4.46M0.07%00.0%Unchanged
Himension Fund13,486$4.40M0.34%−1,816−11.9%Reduced
Quantinno Capital Management LP13,464$4.39M0.02%+7,032+109.3%Added
JustInvest LLC13,390$4.37M0.05%+4,302+47.3%Added
The PNC Financial Services Group, Inc.13,170$4.29M0.00%+45+0.3%Added
Bank of Montreal13,111$4.28M0.00%+2,427+22.7%Added
Mirae Asset Securities (USA) Inc.13,034$4.25M0.19%+13,034New
Daiwa Securities Group Inc.12,941$4.22M0.02%+35+0.3%Added
Public Employees Retirement Association of Colorado12,841$4.19M0.02%−232−1.8%Reduced
Liontrust Investment Partners LLP12,769$4.16M0.06%−6,111−32.4%Reduced
Tredje AP-fonden12,202$3.98M0.03%−3,705−23.3%Reduced
Sterling Capital Management LLC12,089$3.94M0.06%−1,008−7.7%Reduced
Wealthfront Advisers LLC12,084$3.94M0.01%+3,363+38.6%Added
Zacks Investment Management11,931$3.89M0.03%−10,331−46.4%Reduced
EFG Asset Management (Americas) Corp.11,615$3.79M0.70%−1,757−13.1%Reduced
Readystate Asset Management LP11,601$3.78M0.16%+11,601New
Assetmark, Inc11,543$3.76M0.01%+902+8.5%Added
Mirae Asset Global ETFs Holdings Ltd.11,558$3.76M0.01%−2,395−17.2%Reduced
Nordea Investment Management AB11,295$3.64M0.00%+1,060+10.4%Added
Cullen/Frost Bankers, Inc.10,795$3.52M0.04%+78+0.7%Added
Catalyst Funds Management Pty Ltd10,770$3.51M0.97%−8,430−43.9%Reduced
Guggenheim Capital LLC10,649$3.47M0.03%−1,718−13.9%Reduced
Blair William & Co10,592$3.45M0.01%−486−4.4%Reduced
Silvercrest Asset Management Group LLC10,251$3.34M0.02%+430+4.4%Added
Cerity Partners LLC10,113$3.30M0.01%−4,529−30.9%Reduced
Natixis Advisors, L.P.10,109$3.30M0.01%+10,109New
Traynor Capital Management, Inc.10,205$3.29M0.23%+372+3.8%Added
S&CO Inc10,050$3.28M0.21%00.0%Unchanged
Commonwealth Equity Services, LLC9,926$3.24M0.00%+1,455+17.2%Added
Cetera Investment Advisers9,888$3.22M0.01%+1,871+23.3%Added
Polar Asset Management Partners Inc.9,600$3.13M0.08%+9,600New
Employees Retirement System of Texas9,474$3.09M0.03%+9,474New
Amalgamated Bank9,468$3.09M0.02%+615+6.9%Added
Mackenzie Financial Corp9,075$2.96M0.00%−410−4.3%Reduced
St Germain D J Co Inc8,994$2.93M0.13%+8,994New
ASR Vermogensbeheer N.V.8,926$2.91M0.04%+163+1.9%Added
Raiffeisen Bank International AG8,904$2.87M0.04%+8,904New
Schroder Investment Management Group8,580$2.80M0.00%−19,203−69.1%Reduced
Jefferies Financial Group Inc.8,342$2.72M0.04%−7,005−45.6%Reduced
La Banque Postale Asset Management SA8,322$2.71M0.04%+8,322New
Kentucky Retirement Systems8,253$2.69M0.08%−541−6.2%Reduced
Nisa Investment Advisors, LLC8,242$2.69M0.01%+87+1.1%Added
Genus Capital Management Inc.8,230$2.68M0.34%+2,100+34.3%Added
M&T Bank Corp8,203$2.67M0.01%+335+4.3%Added
Man Group plc8,109$2.64M0.01%+1,038+14.7%Added
MetLife Investment Management7,761$2.53M0.01%+466+6.4%Added
Lazard Asset Management LLC7,750$2.53M0.00%−4,138−34.8%Reduced
Advisory Services Network, LLC6,415$2.52M0.04%−7,101−52.5%Reduced
Acadian Asset Management LLC7,719$2.52M0.01%−1,258−14.0%Reduced
Voloridge Investment Management, LLC7,702$2.51M0.01%−54,600−87.6%Reduced
Federation des caisses Desjardins du Quebec7,549$2.46M0.01%−1,873−19.9%Reduced
Shell Asset Management Co7,257$2.37M0.08%+1,602+28.3%Added
Portman Square Capital LLP6,967$2.27M0.24%−5,562−44.4%Reduced
BI Asset Management Fondsmaeglerselskab A/S6,912$2.25M0.02%+1,570+29.4%Added
Andra AP-fonden6,900$2.25M0.03%−9,900−58.9%Reduced
J.P. Marvel Investment Advisors, LLC6,824$2.23M0.36%+2,824+70.6%Added
Motley Fool Asset Management LLC6,652$2.17M0.10%+623+10.3%Added
Sivik Global Healthcare LLC6,500$2.12M0.95%+6,500New
Gulf International Bank (UK) Ltd6,495$2.12M0.07%−869−11.8%Reduced
O'Shaughnessy Asset Management, LLC6,436$2.10M0.01%+2,633+69.2%Added
Profund Advisors LLC6,418$2.09M0.08%−2,408−27.3%Reduced
Hussman Strategic Advisors, Inc.6,300$2.05M0.47%−2,100−25.0%Reduced
Ieq Capital, LLC6,122$2.00M0.01%−37,892−86.1%Reduced
Thematics Asset Management6,118$2.00M0.09%+6,118New
Pathstone Holdings, LLC6,076$1.98M0.01%−222−3.5%Reduced
Maryland State Retirement & Pension System6,021$1.96M0.04%00.0%Unchanged
Gateway Investment Advisers LLC5,889$1.92M0.02%−651−10.0%Reduced
AG2R la Mondiale Gestion D'Actifs5,825$1.90M0.10%00.0%Unchanged
Banque Cantonale Vaudoise5,743$1.87M0.08%+2,015+54.1%Added
Verition Fund Management LLC5,703$1.86M0.01%−5,076−47.1%Reduced
E. Ohman J:or Asset Management AB5,700$1.86M0.05%−100−1.7%Reduced
Toroso Investments, LLC5,574$1.82M0.01%−553−9.0%Reduced
CWM, LLC5,512$1.80M0.01%−11,152−66.9%Reduced
CIBC Asset Management Inc5,458$1.78M0.01%+36+0.7%Added
CIBC World Markets Corp5,417$1.77M0.01%−451−7.7%Reduced
Knollwood Investment Advisory, LLC5,355$1.75M0.17%00.0%Unchanged
NEOS Investment Management LLC5,301$1.73M0.02%−1,174−18.1%Reduced
Tema ETFs LLC5,301$1.73M0.46%−1,174−18.1%Reduced
Wealth Enhancement Advisory Services, LLC5,118$1.70M0.00%−9,286−64.5%Reduced
Burney Co5,142$1.68M0.06%−1,060−17.1%Reduced
Susquehanna Portfolio Strategies, LLC5,005$1.63M0.04%+5,005New