Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 653
- +35 vs. Q1 2025
- Shares held
- 132.1M
- +2.77M (+2.1%) vs. Q1 2025
- Total value
- $43.1B
- +$8.27B (+23.8%) vs. Q1 2025
- New holders
- 98
- 262 more added
- Sold out
- 63
- 214 more reduced
7 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sumitomo Mitsui Trust Holdings, Inc. | 293,542 | $95.7M | 0.06% | +2,066+0.7% | Added |
| Dimensional Fund Advisors LP | 305,563 | $99.6M | 0.02% | −4,256−1.4% | Reduced |
| Allspring Global Investments Holdings, LLC | 312,216 | $100.6M | 0.17% | +41,292+15.2% | Added |
| SEI Investments Co | 308,619 | $100.6M | 0.12% | +31,250+11.3% | Added |
| Wells Fargo & Company | 321,824 | $104.9M | 0.02% | +21,744+7.2% | Added |
| Federated Hermes, Inc. | 323,842 | $105.6M | 0.20% | +59,669+22.6% | Added |
| Gilder Gagnon Howe & Co LLC | 337,088 | $109.9M | 1.17% | −8,487−2.5% | Reduced |
| OrbiMed Advisors LLC | 341,900 | $111.5M | 2.80% | −4,200−1.2% | Reduced |
| Two Sigma Investments, LP | 343,305 | $111.9M | 0.20% | +145,890+73.9% | Added |
| Jennison Associates LLC | 350,070 | $114.2M | 0.07% | +40,851+13.2% | Added |
| Swiss National Bank | 393,800 | $128.4M | 0.08% | +29,600+8.1% | Added |
| Amundi | 394,179 | $130.0M | 0.04% | −60,816−13.4% | Reduced |
| Bank of New York Mellon Corp | 429,769 | $140.1M | 0.03% | −45,063−9.5% | Reduced |
| Royal Bank of Canada | 430,835 | $140.5M | 0.03% | +93,604+27.8% | Added |
| TD Asset Management Inc | 441,177 | $143.9M | 0.12% | −45,407−9.3% | Reduced |
| Pictet Asset Management Holding SA | 464,606 | $151.2M | 0.15% | −16,361−3.4% | Reduced |
| Loomis Sayles & Co L P | 487,328 | $158.9M | 0.20% | −10,156−2.0% | Reduced |
| UBS Group AG | 543,486 | $177.2M | 0.04% | +264,848+95.1% | Added |
| Goldman Sachs Group Inc | 545,316 | $177.8M | 0.03% | +121,949+28.8% | Added |
| Clearbridge Investments, LLC | 557,099 | $181.7M | 0.15% | +549,322+7,063.4% | Added |
| Charles Schwab Investment Management Inc | 571,747 | $186.4M | 0.03% | +25,105+4.6% | Added |
| Holocene Advisors, LP | 596,816 | $194.6M | 0.48% | +596,816 | New |
| Macquarie Group Ltd | 600,111 | $195.7M | 0.24% | +527,519+726.7% | Added |
| Citadel Advisors LLC | 601,199 | $196.0M | 0.17% | +596,963+14,092.6% | Added |
| Franklin Resources Inc | 601,331 | $196.1M | 0.05% | +143,017+31.2% | Added |
| Woodline Partners LP | 623,115 | $203.2M | 1.07% | +466,651+298.2% | Added |
| Deutsche Bank AG | 649,284 | $211.7M | 0.08% | +72,291+12.5% | Added |
| Bellevue Group AG | 676,367 | $220.6M | 4.86% | −91,780−11.9% | Reduced |
| Morgan Stanley | 770,968 | $251.4M | 0.02% | +129,203+20.1% | Added |
| Nuveen, LLC | 774,969 | $252.7M | 0.07% | −108,405−12.3% | Reduced |
| Northern Trust Corp | 831,777 | $271.2M | 0.04% | −33,243−3.8% | Reduced |
| Legal & General Group Plc | 872,771 | $284.6M | 0.07% | −8,340−0.9% | Reduced |
| UBS Asset Management Americas Inc | 958,336 | $312.5M | 0.06% | +222,225+30.2% | Added |
| Winslow Capital Management, LLC | 1,177,439 | $384.0M | 1.28% | −9,739−0.8% | Reduced |
| Bank of America Corp | 1,257,328 | $410.0M | 0.03% | +192,755+18.1% | Added |
| Invesco Ltd. | 1,341,694 | $437.5M | 0.07% | +427,902+46.8% | Added |
| American Century Companies Inc | 1,793,846 | $585.0M | 0.32% | +33,411+1.9% | Added |
| Norges Bank | 2,032,680 | $662.8M | 0.08% | −103,344−4.8% | Reduced |
| JPMorgan Chase & Co | 2,062,008 | $672.4M | 0.05% | −156,864−7.1% | Reduced |
| Wellington Management Group LLP | 2,075,752 | $676.9M | 0.12% | −535,234−20.5% | Reduced |
| Orbis Allan Gray Ltd | 2,121,412 | $691.8M | 3.36% | +486,489+29.8% | Added |
| Geode Capital Management, LLC | 2,398,770 | $779.9M | 0.05% | +75,936+3.3% | Added |
| Baillie Gifford & Co | 3,031,891 | $988.7M | 0.74% | −625,716−17.1% | Reduced |
| Price T Rowe Associates Inc | 3,145,006 | $1.03B | 0.12% | −360,162−10.3% | Reduced |
| State Street Corp | 3,173,105 | $1.03B | 0.04% | −193,478−5.7% | Reduced |
| Dodge & Cox | 3,197,096 | $1.04B | 0.59% | −154,666−4.6% | Reduced |
| T. Rowe Price Investment Management, Inc. | 4,281,279 | $1.40B | 0.88% | −136,866−3.1% | Reduced |
| Regeneron Pharmaceuticals, Inc. | 4,444,445 | $1.45B | 97.60% | 00.0% | Unchanged |
| Capital Research Global Investors | 7,191,656 | $2.35B | 0.47% | +36,928+0.5% | Added |
| BlackRock, Inc. | 9,980,163 | $3.25B | 0.06% | +420,781+4.4% | Added |
| Vanguard Group Inc | 13,297,139 | $4.34B | 0.07% | +240,534+1.8% | Added |
| FMR LLC | 15,806,521 | $5.15B | 0.29% | +496,661+3.2% | Added |
| Capital World Investors | 16,805,007 | $5.48B | 0.80% | +55,384+0.3% | Added |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −330,347−100.0% | Sold out |
| Sofinnova Investments, Inc. | 0 | $0 | 0.00% | −176,181−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −132,960−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −74,185−100.0% | Sold out |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Bridger Management, LLC | 0 | $0 | 0.00% | −34,975−100.0% | Sold out |
| Mediolanum International Funds Ltd | 0 | $0 | 0.00% | −34,729−100.0% | Sold out |
| Alberta Investment Management Corp | 0 | $0 | 0.00% | −17,700−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −14,348−100.0% | Sold out |
| Diadema Partners LP | 0 | $0 | 0.00% | −13,115−100.0% | Sold out |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −9,370−100.0% | Sold out |
| LMR Partners LLP | 0 | $0 | 0.00% | −9,000−100.0% | Sold out |
| FORA Capital, LLC | 0 | $0 | 0.00% | −8,624−100.0% | Sold out |
| SIH Partners, LLLP | 0 | $0 | 0.00% | −7,959−100.0% | Sold out |
| Twin Tree Management, LP | 0 | $0 | 0.00% | −7,074−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −6,704−100.0% | Sold out |
| Privium Fund Management B.V. | 0 | $0 | 0.00% | −5,716−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −5,408−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −5,153−100.0% | Sold out |
| Allstate Corp | 0 | $0 | 0.00% | −4,701−100.0% | Sold out |
| Morgens Waterfall Vintiadis & Co Inc | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −3,795−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −3,720−100.0% | Sold out |
| Perpetual Ltd | 0 | $0 | 0.00% | −3,718−100.0% | Sold out |
| Sanders Morris Harris LLC | 0 | $0 | 0.00% | −3,500−100.0% | Sold out |
| Summit Global Investments | 0 | $0 | 0.00% | −3,145−100.0% | Sold out |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −3,034−100.0% | Sold out |
| PEAK6 LLC | 0 | $0 | 0.00% | −2,295−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −2,451−100.0% | Sold out |
| Accurate Wealth Management, LLC | 0 | $0 | 0.00% | −2,483−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −2,128−100.0% | Sold out |
| Monograph Wealth Advisors, LLC | 0 | $0 | 0.00% | −2,126−100.0% | Sold out |
| Meiji Yasuda Asset Management Co Ltd. | 0 | $0 | 0.00% | −1,986−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −1,488−100.0% | Sold out |
| Yarbrough Capital, LLC | 0 | $0 | 0.00% | −1,376−100.0% | Sold out |
| Allegiance Financial Group Advisory Services LLC | 0 | $0 | 0.00% | −1,353−100.0% | Sold out |
| Ontario Teachers Pension Plan Board | 0 | $0 | 0.00% | −1,345−100.0% | Sold out |
| Kaufman Rossin Wealth, LLC | 0 | $0 | 0.00% | −1,300−100.0% | Sold out |
| NorthCrest Asset Manangement, LLC | 0 | $0 | 0.00% | −1,196−100.0% | Sold out |
| Marex Group plc | 0 | $0 | 0.00% | −1,173−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −1,159−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −1,150−100.0% | Sold out |
| TownSquare Capital, LLC | 0 | $0 | 0.00% | −1,059−100.0% | Sold out |
| Altfest L J & Co Inc | 0 | $0 | 0.00% | −1,050−100.0% | Sold out |
| Polymer Capital Management (US) LLC | 0 | $0 | 0.00% | −961−100.0% | Sold out |
| Parcion Private Wealth LLC | 0 | $0 | 0.00% | −748−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −618−100.0% | Sold out |