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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
653
+35 vs. Q1 2025
Shares held
132.1M
+2.77M (+2.1%) vs. Q1 2025
Total value
$43.1B
+$8.27B (+23.8%) vs. Q1 2025
New holders
98
262 more added
Sold out
63
214 more reduced

7 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 653 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ2 2025: $43.1B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding ALNY in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Arizona State Retirement System37,928$12.4M0.07%+680+1.8%Added
Walleye Capital LLC38,715$12.6M0.12%+36,345+1,533.5%Added
Public Employees Retirement System of Ohio38,752$12.6M0.04%−917−2.3%Reduced
Lansforsakringar Fondforvaltning AB (publ)40,231$13.1M0.08%−2,072−4.9%Reduced
CI Private Wealth, LLC42,152$13.7M0.02%−513−1.2%Reduced
Resona Asset Management Co.,Ltd.43,700$14.2M0.07%+4,780+12.3%Added
State of New Jersey Common Pension Fund D43,859$14.3M0.06%+114+0.3%Added
Storebrand Asset Management AS44,321$14.5M0.04%−726−1.6%Reduced
Eagle Health Investments LP46,086$15.0M3.71%−19,570−29.8%Reduced
KLP Kapitalforvaltning AS49,100$16.0M0.07%+5,400+12.4%Added
Principal Financial Group Inc50,534$16.5M0.01%+15,833+45.6%Added
Rhenman & Partners Asset Management AB51,197$16.7M2.11%+3,000+6.2%Added
U.S. Capital Wealth Advisors, LLC52,027$17.0M0.50%−3,984−7.1%Reduced
Groupama Asset Managment48,385$17.6M0.29%+8,246+20.5%Added
Van Eck Associates Corp54,560$17.8M0.02%−9,584−14.9%Reduced
Integral Health Asset Management, LLC55,000$17.9M1.68%+5,000+10.0%Added
Danske Bank A/S55,007$17.9M0.04%+1,802+3.4%Added
Ikarian Capital, LLC56,594$18.5M6.11%+25,000+79.1%Added
Cercano Management LLC56,953$18.6M0.53%+36,181+174.2%Added
Treasurer of the State of North Carolina58,304$19.0M0.06%−651−1.1%Reduced
Schonfeld Strategic Advisors LLC58,757$19.2M0.14%+55,675+1,806.5%Added
New York State Common Retirement Fund63,272$20.6M0.03%−1,000−1.6%Reduced
Swedbank AB64,315$21.0M0.02%+64,315New
Alliancebernstein L.P.67,131$21.9M0.01%+22,294+49.7%Added
Los Angeles Capital Management LLC67,399$22.0M0.08%−13,463−16.6%Reduced
Zurich Insurance Group Ltd67,794$22.1M0.17%+67,794New
Asset Management One Co.,Ltd.69,310$22.6M0.07%+853+1.2%Added
Capital International Inc71,831$23.4M0.23%+4,870+7.3%Added
PFM Health Sciences, LP72,220$23.6M2.04%−14,925−17.1%Reduced
Palo Alto Investors LP75,535$24.6M5.24%−7,953−9.5%Reduced
State of Wisconsin Investment Board78,106$25.5M0.06%+4,951+6.8%Added
Driehaus Capital Management LLC79,714$26.0M0.21%+22,586+39.5%Added
Casdin Capital, LLC81,500$26.6M2.42%−38,500−32.1%Reduced
HSBC Holdings PLC81,748$26.6M0.02%+20,483+33.4%Added
AXA S.A.82,480$26.9M0.08%−6,172−7.0%Reduced
Capital International Ltd82,800$27.0M1.03%+894+1.1%Added
Prudential Financial Inc83,922$27.4M0.04%−88,084−51.2%Reduced
Adage Capital Partners GP, L.L.C.84,390$27.5M0.05%−197,794−70.1%Reduced
Skandinaviska Enskilda Banken AB (publ)84,888$27.7M0.12%−1,236−1.4%Reduced
Mitsubishi UFJ Trust & Banking Corp85,734$28.0M0.06%−24,931−22.5%Reduced
Manufacturers Life Insurance Company, The86,840$28.3M0.03%−12,029−12.2%Reduced
Tri Locum Partners LP89,525$29.2M8.86%+89,525New
Millennium Management LLC90,445$29.5M0.03%−196,892−68.5%Reduced
Great West Life Assurance Co91,154$29.7M0.05%+7,326+8.7%Added
Nomura Asset Management Co Ltd91,374$29.8M0.08%+4,531+5.2%Added
Parkman Healthcare Partners LLC92,338$30.1M3.48%+23,400+33.9%Added
Panagora Asset Management Inc92,499$30.2M0.14%−4,305−4.4%Reduced
Russell Investments Group, Ltd.93,435$30.4M0.04%−35,761−27.7%Reduced
Barclays PLC94,058$30.7M0.01%−1,661−1.7%Reduced
Envestnet Asset Management Inc95,796$31.2M0.01%+23,749+33.0%Added
Robeco Institutional Asset Management B.V.96,368$31.4M0.05%−7,113−6.9%Reduced
Aviva PLC97,065$31.7M0.07%+7,012+7.8%Added
Neuberger Berman Group LLC99,044$32.3M0.02%+605+0.6%Added
Rock Springs Capital Management LP100,000$32.6M2.03%−43,250−30.2%Reduced
Ensign Peak Advisors, Inc100,209$32.7M0.06%+19,730+24.5%Added
Frontier Capital Management Co LLC103,003$33.6M0.31%+583+0.6%Added
Soleus Capital Management, L.P.106,750$34.8M2.40%+106,750New
D. E. Shaw & Co., Inc.108,276$35.3M0.04%−181,586−62.6%Reduced
HighTower Advisors, LLC109,265$35.6M0.04%−4,592−4.0%Reduced
Korea Investment CORP110,855$36.1M0.08%+5,096+4.8%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.111,785$36.5M0.03%+5,906+5.6%Added
DekaBank Deutsche Girozentrale113,193$36.5M0.07%+151+0.1%Added
Universal- Beteiligungs- und Servicegesellschaft mbH114,366$37.3M0.07%−3,354−2.8%Reduced
Balyasny Asset Management LLC115,275$37.6M0.09%+102,159+778.9%Added
Worldquant Millennium Advisors LLC117,373$38.3M0.19%−73,732−38.6%Reduced
Antipodes Partners Ltd122,804$40.0M1.24%−36,750−23.0%Reduced
Eventide Asset Management, LLC125,902$41.1M0.72%−40,548−24.4%Reduced
State Board of Administration of Florida Retirement System127,050$41.4M0.07%+1,810+1.4%Added
Capital International Sarl128,286$41.8M0.80%+7,126+5.9%Added
BNP Paribas Arbitrage, SA128,634$41.9M0.03%+86,059+202.1%Added
Deerfield Management Company, L.P. (Series C)145,000$47.3M0.86%00.0%Unchanged
FIL Ltd147,937$48.2M0.04%+30,075+25.5%Added
Janus Henderson Group PLC150,421$49.0M0.02%−31,228−17.2%Reduced
Handelsbanken Fonder AB155,362$50.7M0.18%+38,679+33.1%Added
Victory Capital Management Inc156,294$51.0M0.03%+118,645+315.1%Added
Arrowstreet Capital, Limited Partnership169,700$55.3M0.04%+165,645+4,085.0%Added
SCS Capital Management LLC170,662$55.7M0.62%−415−0.2%Reduced
National Pension Service175,046$57.1M0.05%+1,387+0.8%Added
Westfield Capital Management Co LP186,905$60.9M0.26%−5,267−2.7%Reduced
AQR Capital Management LLC188,249$61.3M0.05%−640,095−77.3%Reduced
KBC Group NV193,550$63.1M0.17%+174,238+902.2%Added
Ameriprise Financial Inc193,649$63.1M0.02%+84,513+77.4%Added
California State Teachers Retirement System199,316$65.0M0.07%+1,873+0.9%Added
Rhumbline Advisers200,485$65.4M0.06%+19,022+10.5%Added
Point72 Asset Management, L.P.201,396$65.7M0.16%−99,239−33.0%Reduced
Allianz Asset Management GmbH205,993$67.2M0.09%−12,510−5.7%Reduced
Susquehanna International Group, LLP208,262$67.9M0.10%+137,797+195.6%Added
Voya Investment Management LLC211,045$68.8M0.07%+119,901+131.6%Added
California Public Employees Retirement System211,581$69.0M0.04%+10,100+5.0%Added
Standard Life Aberdeen plc218,624$70.4M0.12%+3,239+1.5%Added
CIBC Private Wealth Group, LLC218,329$71.2M0.13%+12,818+6.2%Added
1832 Asset Management L.P.223,345$72.8M0.13%+79,300+55.1%Added
Polar Capital Holdings Plc237,500$77.4M0.41%−42,500−15.2%Reduced
Candriam Luxembourg S.C.A.238,084$77.6M0.45%−11,835−4.7%Reduced
Marshall Wace, LLP238,573$77.8M0.09%−30,359−11.3%Reduced
Citigroup Inc248,238$80.9M0.06%+53,504+27.5%Added
First Trust Advisors LP251,817$82.1M0.07%+71,357+39.5%Added
Royal London Asset Management Ltd259,071$84.5M0.19%−27,872−9.7%Reduced
Two Sigma Advisers, LP266,100$86.8M0.18%−9,700−3.5%Reduced
Raymond James Financial Inc270,450$88.2M0.03%+1,480+0.6%Added