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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
653
+35 vs. Q1 2025
Shares held
132.1M
+2.77M (+2.1%) vs. Q1 2025
Total value
$43.1B
+$8.27B (+23.8%) vs. Q1 2025
New holders
98
262 more added
Sold out
63
214 more reduced

7 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 653 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ2 2025: $43.1B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding ALNY in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Beacon Pointe Advisors, LLC1,036$337.8K0.00%+169+19.5%Added
Nichols & Pratt Advisers LLP1,043$340.1K0.02%00.0%Unchanged
Crossmark Global Holdings, Inc.1,044$340.4K0.01%+26+2.6%Added
Capital Group Private Client Services, Inc.1,070$348.9K0.00%−786−42.3%Reduced
Coastal Bridge Advisors, LLC1,072$349.6K0.03%+1,072New
Kestra Advisory Services, LLC1,084$353.5K0.00%+126+13.2%Added
Nwam LLC912$357.7K0.02%+5+0.6%Added
Diversified Trust Co1,098$358.0K0.01%−384−25.9%Reduced
Entropy Technologies, LP1,100$358.7K0.03%+1,100New
Towarzystwo Funduszy Inwestycyjnych Pzu SA1,102$359.4K0.10%−60−5.2%Reduced
Wolverine Trading, LLC1,122$362.2K0.01%−1,316−54.0%Reduced
Resources Investment Advisors, LLC.1,117$364.2K0.00%−94−7.8%Reduced
Harvest Fund Management Co., Ltd1,125$366.0K0.02%+1,125New
Clearstead Advisors, LLC1,123$366.2K0.01%−181−13.9%Reduced
Meeder Advisory Services, Inc.1,125$366.9K0.02%+147+15.0%Added
Group One Trading, L.P.1,134$369.8K0.01%−5,068−81.7%Reduced
Snowden Capital Advisors LLC1,136$370.4K0.01%+307+37.0%Added
Peregrine Capital Management LLC1,147$374.0K0.01%00.0%Unchanged
Mathes Company, Inc.1,155$377.0K0.14%+1,155New
Envestnet Portfolio Solutions, Inc.1,164$379.6K0.00%+297+34.3%Added
NewEdge Wealth, LLC902$392.5K0.01%+902New
Wetherby Asset Management Inc1,226$399.8K0.02%+1,226New
Frank, Rimerman Advisors LLC1,227$400.1K0.03%+1,227New
Quantitative Investment Management, LLC1,238$403.0K0.05%+1,238New
Banco Santander, S.A.1,245$406.0K0.00%+1,245New
Cigna Investments Inc1,245$406.0K0.07%−52−4.0%Reduced
Crowley Wealth Management, Inc.1,250$407.6K0.37%00.0%Unchanged
TB Alternative Assets Ltd.1,259$410.5K0.08%−7,909−86.3%Reduced
Fox Run Management, L.L.C.1,263$411.9K0.07%+1,263New
Asahi Life Asset Management Co., Ltd.1,280$417.4K0.24%−160−11.1%Reduced
Plante Moran Financial Advisors, LLC1,285$419.0K0.03%00.0%Unchanged
Beacon Investment Advisory Services, Inc.1,290$420.7K0.02%−398−23.6%Reduced
Ronald Blue Trust, Inc.1,293$421.6K0.00%+135+11.7%Added
North Star Asset Management Inc1,305$425.5K0.02%00.0%Unchanged
Abn Amro Investment Solutions1,310$427.2K0.01%00.0%Unchanged
Oppenheimer Asset Management Inc.1,328$433.0K0.00%+1,328New
Vise Technologies, Inc.1,334$435.1K0.02%+1,334New
Westpac Banking Corp1,355$441.9K0.03%−3,718−73.3%Reduced
Ossiam1,355$441.9K0.00%+19+1.4%Added
Voleon Capital Management LP1,356$442.2K0.02%−10,558−88.6%Reduced
Steward Partners Investment Advisory, LLC1,357$442.3K0.00%+295+27.8%Added
Souders Financial Advisors1,359$443.2K0.06%−434−24.2%Reduced
Cambridge Investment Research Advisors, Inc.1,384$451.0K0.00%+595+75.4%Added
Banque Pictet & Cie SA1,391$453.6K0.00%−92−6.2%Reduced
Fulton Bank, N.A.1,421$463.4K0.02%+46+3.3%Added
Ewing Morris & Co. Investment Partners Ltd.1,440$469.6K0.21%+1,440New
Avantax Advisory Services, Inc.1,446$471.5K0.00%+1,446New
Sara-Bay Financial1,450$472.8K0.17%+450+45.0%Added
Virtus Investment Advisers, Inc.1,459$475.8K0.16%−8−0.5%Reduced
High Net Worth Advisory Group LLC1,500$489.1K0.13%00.0%Unchanged
Wiley Bros.-Aintree Capital, LLC1,530$497.9K0.00%+702+84.8%Added
Qsemble Capital Management, LP1,530$498.9K0.05%+334+27.9%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,533$499.9K0.00%00.0%Unchanged
EntryPoint Capital, LLC1,550$505.4K0.25%−814−34.4%Reduced
Forum Financial Management, LP1,556$507.4K0.01%+129+9.0%Added
Yousif Capital Management, LLC1,567$511.0K0.01%−106−6.3%Reduced
United Capital Financial Advisers, LLC1,575$513.6K0.00%+43+2.8%Added
Coldstream Capital Management Inc1,602$522.3K0.01%+523+48.5%Added
S-Bank Fund Management Ltd1,614$526.3K0.08%−146−8.3%Reduced
Ballentine Partners, LLC1,617$527.3K0.01%−8−0.5%Reduced
Kennedy Capital Management, Inc.1,668$543.9K0.01%+127+8.2%Added
Bryn Mawr Trust Co1,686$549.8K0.01%+588+53.6%Added
V-Square Quantitative Management LLC1,692$551.7K0.07%+1,321+356.1%Added
Fort Sheridan Advisors LLC1,701$554.7K0.08%00.0%Unchanged
Principal Securities, Inc.1,714$558.9K0.01%+527+44.4%Added
Oppenheimer & Co Inc1,716$559.6K0.01%00.0%Unchanged
Wedmont Private Capital1,761$565.1K0.02%+169+10.6%Added
Vestmark Advisory Solutions, Inc.1,740$567.4K0.01%+1,740New
Siemens Fonds Invest GmbH1,843$601.0K0.04%+372+25.3%Added
Quadrature Capital Ltd1,887$614.7K0.01%−16,624−89.8%Reduced
Merit Financial Group, LLC1,890$616.2K0.01%−3,424−64.4%Reduced
GraniteShares Advisors LLC1,899$619.2K0.38%−211−10.0%Reduced
Signaturefd, LLC1,906$621.6K0.01%+151+8.6%Added
Emerald Advisers, LLC1,941$632.9K0.02%+445+29.7%Added
Lecap Asset Management Ltd1,985$647.3K0.23%+276+16.1%Added
Security National Bank of So Dak2,000$652.2K0.36%00.0%Unchanged
Archford Capital Strategies, LLC2,017$657.7K0.08%−2−0.1%Reduced
Park Avenue Securities LLC2,085$680.0K0.01%+2,085New
New York Life Investment Management LLC2,103$685.8K0.01%−111−5.0%Reduced
Sumitomo Life Insurance Co2,118$690.7K0.05%+2,118New
QRG Capital Management, Inc.2,136$696.5K0.01%+187+9.6%Added
Ethic Inc.2,176$702.6K0.01%+133+6.5%Added
Bannerman Wealth Management Group, LLC2,164$705.7K0.54%−565−20.7%Reduced
Sava Infond d.o.o.2,180$710.9K0.11%+100+4.8%Added
Everhart Financial Group, Inc.2,193$715.1K0.08%+406+22.7%Added
UniSuper Management Pty Ltd2,200$717.4K0.00%−300−12.0%Reduced
Convergence Investment Partners, LLC2,259$736.6K0.19%+2,259New
Nixon Peabody Trust Co2,337$762.1K0.06%+60+2.6%Added
Kovitz Investment Group Partners, LLC2,350$766.4K0.00%+10.0%Added
Squarepoint Ops LLC2,446$797.6K0.00%−3,822−61.0%Reduced
Oxford Asset Management LLP2,468$804.8K0.26%+2,468New
Mercer Global Advisors Inc2,563$835.7K0.00%−647−20.2%Reduced
Pallas Capital Advisors LLC2,570$838.1K0.03%−4,065−61.3%Reduced
Azzad Asset Management Inc2,651$864.5K0.09%+2,651New
Bank of Nova Scotia2,679$873.8K0.00%−1,827−40.5%Reduced
Greenleaf Trust2,730$890.2K0.01%−20−0.7%Reduced
Shepherd Financial Partners LLC2,736$892.2K0.09%00.0%Unchanged
Keybank National Association2,757$899.0K0.00%−37−1.3%Reduced
Horizon Kinetics Asset Management LLC2,759$899.7K0.01%−121−4.2%Reduced
Exchange Traded Concepts, LLC2,806$915.0K0.01%−909−24.5%Reduced