Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 625
- +39 vs. Q4 2024
- Shares held
- 129.4M
- +2.10M (+1.7%) vs. Q4 2024
- Total value
- $34.8B
- +$4.88B (+16.3%) vs. Q4 2024
- New holders
- 106
- 235 more added
- Sold out
- 67
- 205 more reduced
8 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| New York State Common Retirement Fund | 64,272 | $17.4M | 0.03% | −7,956−11.0% | Reduced |
| Iron Triangle Partners LP | 65,409 | $17.7M | 2.78% | +65,409 | New |
| Eagle Health Investments LP | 65,656 | $17.7M | 4.60% | −10,600−13.9% | Reduced |
| Capital International Inc | 66,961 | $18.1M | 0.22% | −38,124−36.3% | Reduced |
| Asset Management One Co.,Ltd. | 68,457 | $18.5M | 0.06% | +3,094+4.7% | Added |
| Parkman Healthcare Partners LLC | 68,938 | $18.6M | 2.21% | +30,266+78.3% | Added |
| Susquehanna International Group, LLP | 70,465 | $19.0M | 0.03% | +59,648+551.4% | Added |
| Envestnet Asset Management Inc | 72,047 | $19.5M | 0.01% | +6,033+9.1% | Added |
| Macquarie Group Ltd | 72,592 | $19.6M | 0.02% | +11,928+19.7% | Added |
| State of Wisconsin Investment Board | 73,155 | $19.8M | 0.05% | −5,220−6.7% | Reduced |
| J. Goldman & Co LP | 74,185 | $20.0M | 0.71% | +74,185 | New |
| Ensign Peak Advisors, Inc | 80,479 | $21.7M | 0.04% | +4,015+5.3% | Added |
| Los Angeles Capital Management LLC | 80,862 | $21.8M | 0.10% | −13,960−14.7% | Reduced |
| Capital International Ltd | 81,906 | $22.1M | 0.96% | +1,624+2.0% | Added |
| Palo Alto Investors LP | 83,488 | $22.5M | 4.29% | −57,193−40.7% | Reduced |
| Great West Life Assurance Co | 83,828 | $22.7M | 0.04% | +6,909+9.0% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 86,124 | $23.3M | 0.11% | −39,367−31.4% | Reduced |
| Nomura Asset Management Co Ltd | 86,843 | $23.4M | 0.07% | +4,058+4.9% | Added |
| PFM Health Sciences, LP | 87,145 | $23.5M | 1.80% | +87,145 | New |
| AXA S.A. | 88,652 | $23.9M | 0.08% | −6,654−7.0% | Reduced |
| Aviva PLC | 90,053 | $24.3M | 0.06% | +12,809+16.6% | Added |
| Voya Investment Management LLC | 91,144 | $24.6M | 0.03% | −3,942−4.1% | Reduced |
| Barclays PLC | 95,719 | $25.8M | 0.01% | −8,128−7.8% | Reduced |
| Panagora Asset Management Inc | 96,804 | $26.1M | 0.13% | +41,340+74.5% | Added |
| Neuberger Berman Group LLC | 98,439 | $26.6M | 0.02% | −11,269−10.3% | Reduced |
| Jane Street Group, LLC | 98,551 | $26.6M | 0.05% | −62,086−38.6% | Reduced |
| Manufacturers Life Insurance Company, The | 98,869 | $26.7M | 0.03% | −10,233−9.4% | Reduced |
| Frontier Capital Management Co LLC | 102,420 | $27.7M | 0.30% | −2,298−2.2% | Reduced |
| Robeco Institutional Asset Management B.V. | 103,481 | $27.9M | 0.05% | +3,487+3.5% | Added |
| Korea Investment CORP | 105,759 | $28.6M | 0.07% | +12,156+13.0% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 105,879 | $28.6M | 0.03% | +11,181+11.8% | Added |
| Ameriprise Financial Inc | 109,136 | $29.5M | 0.01% | −18,937−14.8% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 110,665 | $29.9M | 0.08% | −6,021−5.2% | Reduced |
| DekaBank Deutsche Girozentrale | 113,042 | $30.0M | 0.06% | −151−0.1% | Reduced |
| HighTower Advisors, LLC | 113,857 | $30.7M | 0.04% | −1,523−1.3% | Reduced |
| Handelsbanken Fonder AB | 116,683 | $31.5M | 0.13% | +62,337+114.7% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 117,720 | $31.8M | 0.06% | −6,640−5.3% | Reduced |
| FIL Ltd | 117,862 | $31.8M | 0.03% | +95,796+434.1% | Added |
| Casdin Capital, LLC | 120,000 | $32.4M | 2.65% | −20,000−14.3% | Reduced |
| Capital International Sarl | 121,160 | $32.7M | 0.74% | +6,018+5.2% | Added |
| State Board of Administration of Florida Retirement System | 125,240 | $33.8M | 0.07% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 129,196 | $34.9M | 0.05% | +56,036+76.6% | Added |
| SG Americas Securities, LLC | 132,960 | $35.9M | 0.12% | +131,293+7,876.0% | Added |
| Rock Springs Capital Management LP | 143,250 | $38.7M | 2.21% | −112,950−44.1% | Reduced |
| 1832 Asset Management L.P. | 144,045 | $38.9M | 0.07% | +144,045 | New |
| Deerfield Management Company, L.P. (Series C) | 145,000 | $39.2M | 0.78% | −191−0.1% | Reduced |
| Jacobs Levy Equity Management, Inc | 152,970 | $41.3M | 0.16% | +152,970 | New |
| Woodline Partners LP | 156,464 | $42.2M | 0.27% | +156,464 | New |
| Antipodes Partners Ltd | 159,554 | $43.1M | 1.35% | +25,795+19.3% | Added |
| Eventide Asset Management, LLC | 166,450 | $44.9M | 0.90% | −73,968−30.8% | Reduced |
| CIBC Private Wealth Group, LLC | 205,511 | $46.1M | 0.10% | +2,143+1.1% | Added |
| SCS Capital Management LLC | 171,077 | $46.2M | 0.59% | +171,077 | New |
| Prudential Financial Inc | 172,006 | $46.4M | 0.07% | +153,253+817.2% | Added |
| National Pension Service | 173,659 | $46.9M | 0.05% | +14,148+8.9% | Added |
| Sofinnova Investments, Inc. | 176,181 | $47.6M | 3.59% | +66,024+59.9% | Added |
| First Trust Advisors LP | 180,460 | $48.7M | 0.04% | −147,322−44.9% | Reduced |
| Janus Henderson Group PLC | 181,649 | $48.8M | 0.03% | −28,431−13.5% | Reduced |
| Rhumbline Advisers | 181,463 | $49.0M | 0.05% | +1,885+1.0% | Added |
| Worldquant Millennium Advisors LLC | 191,105 | $51.6M | 0.33% | +40,914+27.2% | Added |
| Westfield Capital Management Co LP | 192,172 | $51.9M | 0.25% | −23,954−11.1% | Reduced |
| Citigroup Inc | 194,734 | $52.6M | 0.04% | +107,837+124.1% | Added |
| Two Sigma Investments, LP | 197,415 | $53.3M | 0.12% | +90,298+84.3% | Added |
| California State Teachers Retirement System | 197,443 | $53.3M | 0.07% | +1,081+0.6% | Added |
| California Public Employees Retirement System | 201,481 | $54.4M | 0.04% | −2,651−1.3% | Reduced |
| Standard Life Aberdeen plc | 215,385 | $57.1M | 0.11% | +24,544+12.9% | Added |
| Allianz Asset Management GmbH | 218,503 | $59.0M | 0.09% | +109,632+100.7% | Added |
| Candriam Luxembourg S.C.A. | 249,919 | $67.5M | 0.42% | −32,488−11.5% | Reduced |
| Allspring Global Investments Holdings, LLC | 270,924 | $69.3M | 0.12% | +270,924 | New |
| Federated Hermes, Inc. | 264,173 | $71.3M | 0.15% | +14,582+5.8% | Added |
| Marshall Wace, LLP | 268,932 | $72.6M | 0.10% | −109,717−29.0% | Reduced |
| Raymond James Financial Inc | 268,970 | $72.6M | 0.03% | −8,516−3.1% | Reduced |
| Two Sigma Advisers, LP | 275,800 | $74.5M | 0.17% | +197,000+250.0% | Added |
| SEI Investments Co | 277,369 | $74.9M | 0.10% | +11,369+4.3% | Added |
| UBS Group AG | 278,638 | $75.2M | 0.02% | −11,328−3.9% | Reduced |
| Polar Capital Holdings Plc | 280,000 | $75.6M | 0.47% | −30,000−9.7% | Reduced |
| Adage Capital Partners GP, L.L.C. | 282,184 | $76.2M | 0.14% | +189,128+203.2% | Added |
| Royal London Asset Management Ltd | 286,943 | $77.5M | 0.18% | +5,434+1.9% | Added |
| Millennium Management LLC | 287,337 | $77.6M | 0.08% | −46,105−13.8% | Reduced |
| D. E. Shaw & Co., Inc. | 289,862 | $78.3M | 0.09% | −73,223−20.2% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 291,476 | $78.7M | 0.06% | +4,773+1.7% | Added |
| Wells Fargo & Company | 300,080 | $81.0M | 0.02% | +23,118+8.3% | Added |
| Point72 Asset Management, L.P. | 300,635 | $81.2M | 0.23% | +300,635 | New |
| Jennison Associates LLC | 309,219 | $83.5M | 0.06% | +49,306+19.0% | Added |
| Dimensional Fund Advisors LP | 309,819 | $83.6M | 0.02% | −23,842−7.1% | Reduced |
| Qube Research & Technologies Ltd | 330,347 | $89.2M | 0.14% | −154,913−31.9% | Reduced |
| Royal Bank of Canada | 337,231 | $91.1M | 0.02% | +27,044+8.7% | Added |
| Gilder Gagnon Howe & Co LLC | 345,575 | $93.3M | 1.22% | −19,888−5.4% | Reduced |
| OrbiMed Advisors LLC | 346,100 | $93.5M | 2.24% | −69,500−16.7% | Reduced |
| Swiss National Bank | 364,200 | $98.3M | 0.07% | +1,600+0.4% | Added |
| Goldman Sachs Group Inc | 423,367 | $114.3M | 0.02% | +116,912+38.1% | Added |
| Amundi | 454,995 | $119.3M | 0.04% | −41,306−8.3% | Reduced |
| Franklin Resources Inc | 458,314 | $123.8M | 0.04% | +44,175+10.7% | Added |
| Bank of New York Mellon Corp | 474,832 | $128.2M | 0.03% | −4,371−0.9% | Reduced |
| Pictet Asset Management Holding SA | 480,967 | $129.7M | 0.14% | +50,355+11.7% | Added |
| TD Asset Management Inc | 486,584 | $131.4M | 0.12% | −17,454−3.5% | Reduced |
| Loomis Sayles & Co L P | 497,484 | $134.3M | 0.19% | −5,561−1.1% | Reduced |
| Charles Schwab Investment Management Inc | 546,642 | $147.6M | 0.03% | +32,680+6.4% | Added |
| Nuveen, LLC | 883,374 | $148.7M | 0.05% | +883,374 | New |
| Deutsche Bank AG | 576,993 | $155.8M | 0.06% | +20,414+3.7% | Added |
| Morgan Stanley | 641,765 | $173.3M | 0.01% | −85,459−11.8% | Reduced |