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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
625
+39 vs. Q4 2024
Shares held
129.4M
+2.10M (+1.7%) vs. Q4 2024
Total value
$34.8B
+$4.88B (+16.3%) vs. Q4 2024
New holders
106
235 more added
Sold out
67
205 more reduced

8 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 625 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2025: $34.8B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding ALNY in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tower Research Capital LLC (TRC)1,383$366.6K0.01%−3,998−74.3%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,533$370.9K0.00%00.0%Unchanged
Fulton Bank, N.A.1,375$371.3K0.01%+32+2.4%Added
Yarbrough Capital, LLC1,376$371.5K0.02%00.0%Unchanged
Wedmont Private Capital1,592$378.5K0.02%+107+7.2%Added
Forum Financial Management, LP1,427$385.3K0.01%−37−2.5%Reduced
Asahi Life Asset Management Co., Ltd.1,440$388.8K0.25%−40−2.7%Reduced
Virtus Investment Advisers, Inc.1,467$396.1K0.11%+1,467New
Siemens Fonds Invest GmbH1,471$397.2K0.03%+106+7.8%Added
Diversified Trust Co1,482$400.2K0.01%−999−40.3%Reduced
Banque Pictet & Cie SA1,483$400.4K0.00%+1,483New
XTX Topco Ltd1,488$401.8K0.02%+1,488New
Emerald Advisers, LLC1,496$403.9K0.02%−84−5.3%Reduced
High Net Worth Advisory Group LLC1,500$405.0K0.11%00.0%Unchanged
United Capital Financial Advisers, LLC1,532$413.7K0.00%+52+3.5%Added
Kennedy Capital Management, Inc.1,541$416.1K0.01%+6+0.4%Added
Ballentine Partners, LLC1,625$438.8K0.01%+52+3.3%Added
Advisor Group Holdings, Inc.1,629$440.0K0.00%−3,200−66.3%Reduced
Yousif Capital Management, LLC1,673$451.7K0.01%+31+1.9%Added
New York State Teachers Retirement System1,678$453.0K0.00%−4,158−71.2%Reduced
Beacon Investment Advisory Services, Inc.1,688$455.8K0.02%−2,033−54.6%Reduced
Vontobel Holding Ltd.1,691$456.6K0.00%−113−6.3%Reduced
Fort Sheridan Advisors LLC1,701$459.3K0.07%00.0%Unchanged
Lecap Asset Management Ltd1,709$461.5K0.11%+1,709New
Point72 (DIFC) Ltd1,712$462.2K0.04%+1,712New
Oppenheimer & Co Inc1,716$463.4K0.01%00.0%Unchanged
Signaturefd, LLC1,755$473.9K0.01%+115+7.0%Added
S-Bank Fund Management Ltd1,760$475.2K0.09%+1,760New
Everhart Financial Group, Inc.1,787$482.5K0.07%+191+12.0%Added
Souders Financial Advisors1,793$484.1K0.07%−947−34.6%Reduced
Summit Trail Advisors, LLC1,803$486.8K0.02%+518+40.3%Added
Capital Group Private Client Services, Inc.1,856$501.2K0.00%−39,669−95.5%Reduced
Graham Capital Management, L.P.1,910$515.7K0.02%−440−18.7%Reduced
Ethic Inc.2,043$522.6K0.01%−2,843−58.2%Reduced
QRG Capital Management, Inc.1,949$526.3K0.01%+964+97.9%Added
Meiji Yasuda Asset Management Co Ltd.1,986$536.3K0.02%00.0%Unchanged
Security National Bank of So Dak2,000$540.0K0.31%00.0%Unchanged
Kornitzer Capital Management Inc2,000$540.0K0.01%+2,000New
Archford Capital Strategies, LLC2,019$545.2K0.08%+2,019New
Prudential PLC2,047$552.7K0.00%−2,233−52.2%Reduced
Sava Infond d.o.o.2,080$561.6K0.11%+350+20.2%Added
GraniteShares Advisors LLC2,110$569.7K0.36%−155−6.8%Reduced
Monograph Wealth Advisors, LLC2,126$574.1K0.08%−12−0.6%Reduced
Corebridge Financial, Inc.2,128$574.6K0.00%−81−3.7%Reduced
Accurate Wealth Management, LLC2,483$590.4K0.11%+2,483New
New York Life Investment Management LLC2,214$597.8K0.01%−170−7.1%Reduced
Ci Investments Inc.2,221$600.0K0.00%−1,263−36.3%Reduced
Aster Capital Management (DIFC) Ltd2,451$604.8K0.11%+2,451New
Nixon Peabody Trust Co2,277$614.8K0.05%−16−0.7%Reduced
PEAK6 LLC2,295$619.7K0.02%−8,407−78.6%Reduced
Kovitz Investment Group Partners, LLC2,349$634.2K0.00%−292−11.1%Reduced
EntryPoint Capital, LLC2,364$638.3K0.29%−178−7.0%Reduced
Walleye Capital LLC2,370$639.9K0.01%−17,746−88.2%Reduced
Wolverine Trading, LLC2,438$654.5K0.02%−4,885−66.7%Reduced
Vestcor Inc2,461$665.0K0.02%+6+0.2%Added
UniSuper Management Pty Ltd2,500$675.0K0.01%00.0%Unchanged
Central Pacific Bank - Trust Division2,653$716.4K0.10%+1,648+164.0%Added
Vident Advisory, LLC2,667$720.1K0.01%+1,340+101.0%Added
Buckingham Strategic Partners2,724$735.5K0.01%+1,862+216.0%Added
Steel Peak Wealth Management LLC2,727$736.2K0.03%−753−21.6%Reduced
Bannerman Wealth Management Group, LLC2,729$736.9K0.60%+1,338+96.2%Added
Shepherd Financial Partners LLC2,736$738.8K0.09%00.0%Unchanged
Integrated Wealth Concepts LLC2,739$739.6K0.01%+227+9.0%Added
Greenleaf Trust2,750$742.6K0.01%+28+1.0%Added
Keybank National Association2,794$754.4K0.00%−68−2.4%Reduced
Horizon Kinetics Asset Management LLC2,880$777.7K0.01%00.0%Unchanged
Generali Investments CEE, investicni spolecnost, a.s.2,900$783.1K0.07%00.0%Unchanged
Regal Investment Advisors LLC2,906$784.7K0.06%−252−8.0%Reduced
Everence Capital Management Inc2,970$802.0K0.05%+450+17.9%Added
Grandfield & Dodd, LLC3,032$818.7K0.05%+659+27.8%Added
Persistent Asset Partners Ltd3,034$819.2K0.72%+3,034New
Schonfeld Strategic Advisors LLC3,082$832.2K0.01%−123,918−97.6%Reduced
Summit Global Investments3,145$849.0K0.06%+3,145New
Mercer Global Advisors Inc3,210$866.7K0.00%+610+23.5%Added
B. Metzler seel. Sohn & Co. AG3,233$873.0K0.01%−46−1.4%Reduced
Hall Laurie J Trustee3,250$877.6K0.31%00.0%Unchanged
Credit Agricole S A3,287$887.6K0.00%−706−17.7%Reduced
Sanctuary Advisors, LLC3,290$888.4K0.01%−1,625−33.1%Reduced
GF Fund Management Co. Ltd.3,302$891.6K0.02%+594+21.9%Added
Sanders Morris Harris LLC3,500$895.2K0.14%00.0%Unchanged
Orion Capital Management LLC3,340$901.9K0.38%00.0%Unchanged
Spectrum Planning & Advisory Services Inc.3,359$907.0K0.75%00.0%Unchanged
Walleye Trading LLC3,360$907.3K0.03%+3,360New
Tobam3,366$909.0K0.39%−8,418−71.4%Reduced
Sequoia Financial Advisors, LLC3,395$916.8K0.01%+99+3.0%Added
Rakuten Investment Management, Inc.3,559$955.4K0.00%+3,559New
Truist Financial Corp3,624$978.6K0.00%−774−17.6%Reduced
Exchange Traded Concepts, LLC3,715$1.00M0.02%−118−3.1%Reduced
Perpetual Ltd3,718$1.00M0.01%−5,213−58.4%Reduced
Y-Intercept (Hong Kong) Ltd3,720$1.00M0.07%−796−17.6%Reduced
Banque Cantonale Vaudoise3,728$1.01M0.04%+3,728New
Kentucky Retirement Systems Insurance Trust Fund3,746$1.01M0.07%+3,746New
Point72 Hong Kong Ltd3,795$1.02M0.07%+3,795New
O'Shaughnessy Asset Management, LLC3,803$1.03M0.01%+360+10.5%Added
Brinker Capital Investments, LLC3,857$1.04M0.01%+113+3.0%Added
Orion Portfolio Solutions, LLC3,857$1.04M0.01%+113+3.0%Added
Gilbert & Cook, Inc.3,904$1.05M0.15%00.0%Unchanged
Atlantic Trust, LLC3,992$1.08M0.24%+11+0.3%Added
Howland Capital Management LLC4,000$1.08M0.05%00.0%Unchanged
J.P. Marvel Investment Advisors, LLC4,000$1.08M0.19%00.0%Unchanged