Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 594
- +35 vs. Q3 2024
- Shares held
- 127.8M
- +4.29M (+3.5%) vs. Q3 2024
- Total value
- $30.1B
- −$3.90B (−11.5%) vs. Q3 2024
- New holders
- 98
- 239 more added
- Sold out
- 63
- 180 more reduced
10 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Robeco Institutional Asset Management B.V. | 99,994 | $23.5M | 0.04% | +26,426+35.9% | Added |
| Barclays PLC | 103,847 | $24.4M | 0.01% | −1,338−1.3% | Reduced |
| Frontier Capital Management Co LLC | 104,718 | $24.6M | 0.23% | −6,513−5.9% | Reduced |
| Capital International Inc | 105,085 | $24.7M | 0.29% | −20,136−16.1% | Reduced |
| Two Sigma Investments, LP | 107,117 | $25.2M | 0.06% | +87,969+459.4% | Added |
| Allianz Asset Management GmbH | 108,871 | $25.6M | 0.04% | +82,065+306.1% | Added |
| Manufacturers Life Insurance Company, The | 109,102 | $25.7M | 0.02% | −82,280−43.0% | Reduced |
| Neuberger Berman Group LLC | 109,708 | $25.8M | 0.02% | +3,511+3.3% | Added |
| Sofinnova Investments, Inc. | 110,157 | $25.9M | 1.90% | +110,157 | New |
| DekaBank Deutsche Girozentrale | 113,193 | $26.5M | 0.05% | 00.0% | Unchanged |
| Capital International Sarl | 115,142 | $27.1M | 0.63% | −19,931−14.8% | Reduced |
| HighTower Advisors, LLC | 115,380 | $27.2M | 0.04% | −410−0.4% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 116,686 | $27.5M | 0.06% | −3,646−3.0% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 124,360 | $29.3M | 0.06% | +124,360 | New |
| State Board of Administration of Florida Retirement System | 125,240 | $29.5M | 0.06% | −4,177−3.2% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 125,491 | $29.6M | 0.13% | −24,628−16.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 127,000 | $29.9M | 0.19% | +99,133+355.7% | Added |
| Squarepoint Ops LLC | 127,697 | $30.0M | 0.08% | +84,996+199.0% | Added |
| Ameriprise Financial Inc | 128,073 | $30.1M | 0.01% | −9,765−7.1% | Reduced |
| Antipodes Partners Ltd | 133,759 | $31.5M | 1.09% | −5,616−4.0% | Reduced |
| Casdin Capital, LLC | 140,000 | $32.9M | 2.20% | −30,000−17.6% | Reduced |
| Palo Alto Investors LP | 140,681 | $33.1M | 5.13% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 145,191 | $34.2M | 0.65% | +191+0.1% | Added |
| Worldquant Millennium Advisors LLC | 150,191 | $35.3M | 0.23% | +91,671+156.6% | Added |
| National Pension Service | 159,511 | $37.5M | 0.04% | −36,876−18.8% | Reduced |
| Jane Street Group, LLC | 160,637 | $37.8M | 0.06% | +24,356+17.9% | Added |
| Canada Pension Plan Investment Board | 174,021 | $40.9M | 0.04% | −170,837−49.5% | Reduced |
| Rhumbline Advisers | 179,578 | $42.3M | 0.04% | −1,850−1.0% | Reduced |
| Standard Life Aberdeen plc | 190,841 | $45.2M | 0.08% | −9,228−4.6% | Reduced |
| California State Teachers Retirement System | 196,362 | $46.2M | 0.05% | +5,037+2.6% | Added |
| California Public Employees Retirement System | 204,132 | $48.0M | 0.03% | −7,649−3.6% | Reduced |
| CIBC Private Wealth Group, LLC | 203,368 | $48.9M | 0.09% | −5,118−2.5% | Reduced |
| Janus Henderson Group PLC | 210,080 | $49.4M | 0.03% | −9,257−4.2% | Reduced |
| Westfield Capital Management Co LP | 216,126 | $50.9M | 0.22% | +216,126 | New |
| Eventide Asset Management, LLC | 240,418 | $56.6M | 1.03% | +16,085+7.2% | Added |
| Federated Hermes, Inc. | 249,591 | $58.7M | 0.13% | +80,668+47.8% | Added |
| Rock Springs Capital Management LP | 256,200 | $60.3M | 2.30% | +6,200+2.5% | Added |
| Jennison Associates LLC | 259,913 | $61.2M | 0.04% | +259,913 | New |
| SEI Investments Co | 266,000 | $62.6M | 0.08% | +28,093+11.8% | Added |
| Wells Fargo & Company | 276,962 | $65.2M | 0.02% | +10,465+3.9% | Added |
| Raymond James Financial Inc | 277,486 | $65.3M | 0.02% | +277,486 | New |
| CI Private Wealth, LLC | 278,566 | $65.5M | 0.11% | +810.0% | Added |
| Royal London Asset Management Ltd | 281,509 | $66.2M | 0.16% | +1,759+0.6% | Added |
| Candriam Luxembourg S.C.A. | 282,407 | $66.5M | 0.38% | −69,261−19.7% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 286,703 | $67.5M | 0.05% | +8,462+3.0% | Added |
| UBS Group AG | 289,966 | $68.2M | 0.02% | +134,295+86.3% | Added |
| Goldman Sachs Group Inc | 306,455 | $72.1M | 0.01% | −49,645−13.9% | Reduced |
| Polar Capital Holdings Plc | 310,000 | $72.9M | 0.41% | 00.0% | Unchanged |
| Royal Bank of Canada | 310,187 | $73.0M | 0.02% | −100,879−24.5% | Reduced |
| First Trust Advisors LP | 327,782 | $77.1M | 0.07% | +42,211+14.8% | Added |
| Millennium Management LLC | 333,442 | $78.5M | 0.07% | +82,479+32.9% | Added |
| Dimensional Fund Advisors LP | 333,661 | $78.5M | 0.02% | +32,272+10.7% | Added |
| Swiss National Bank | 362,600 | $85.3M | 0.06% | −12,800−3.4% | Reduced |
| D. E. Shaw & Co., Inc. | 363,085 | $85.4M | 0.09% | +30,780+9.3% | Added |
| Gilder Gagnon Howe & Co LLC | 365,463 | $86.0M | 0.93% | −18,530−4.8% | Reduced |
| Marshall Wace, LLP | 378,649 | $89.1M | 0.11% | +315,182+496.6% | Added |
| Franklin Resources Inc | 414,139 | $97.5M | 0.03% | +31,166+8.1% | Added |
| OrbiMed Advisors LLC | 415,600 | $97.8M | 2.03% | +165,300+66.0% | Added |
| Bank of America Corp | 418,552 | $98.5M | 0.01% | −132,220−24.0% | Reduced |
| Pictet Asset Management Holding SA | 430,612 | $101.3M | 0.11% | −234,110−35.2% | Reduced |
| Nuveen Asset Management, LLC | 448,881 | $105.6M | 0.03% | +7,789+1.8% | Added |
| Bank of New York Mellon Corp | 479,203 | $112.8M | 0.02% | +4,764+1.0% | Added |
| Qube Research & Technologies Ltd | 485,260 | $114.2M | 0.19% | +333,098+218.9% | Added |
| Loomis Sayles & Co L P | 503,045 | $118.4M | 0.15% | −22,258−4.2% | Reduced |
| TD Asset Management Inc | 504,038 | $118.6M | 0.10% | +15,755+3.2% | Added |
| Amundi | 496,301 | $119.4M | 0.04% | −97,019−16.4% | Reduced |
| Charles Schwab Investment Management Inc | 513,962 | $120.9M | 0.02% | +26,614+5.5% | Added |
| Deutsche Bank AG | 556,579 | $131.0M | 0.05% | +17,308+3.2% | Added |
| Invesco Ltd. | 558,490 | $131.4M | 0.02% | −137,378−19.7% | Reduced |
| UBS Asset Management Americas Inc | 710,598 | $167.2M | 0.04% | +4,367+0.6% | Added |
| Morgan Stanley | 727,224 | $171.1M | 0.01% | +108,661+17.6% | Added |
| Bellevue Group AG | 770,268 | $181.3M | 3.49% | −38,827−4.8% | Reduced |
| AQR Capital Management LLC | 813,356 | $191.4M | 0.25% | +307,702+60.9% | Added |
| Legal & General Group Plc | 828,917 | $195.1M | 0.05% | +37,188+4.7% | Added |
| Northern Trust Corp | 878,860 | $206.8M | 0.03% | +143,941+19.6% | Added |
| Winslow Capital Management, LLC | 1,020,567 | $240.1M | 0.85% | +58,960+6.1% | Added |
| Capital International Investors | 1,418,602 | $333.8M | 0.06% | −2,552,261−64.3% | Reduced |
| Orbis Allan Gray Ltd | 1,472,802 | $346.6M | 1.86% | +204,690+16.1% | Added |
| American Century Companies Inc | 1,604,024 | $377.4M | 0.22% | +11,291+0.7% | Added |
| Geode Capital Management, LLC | 2,206,800 | $518.4M | 0.04% | +59,597+2.8% | Added |
| JPMorgan Chase & Co | 2,250,060 | $529.5M | 0.04% | +87,116+4.0% | Added |
| Norges Bank | 2,456,082 | $577.9M | 0.08% | +80,547+3.4% | Added |
| Price T Rowe Associates Inc | 3,319,385 | $781.1M | 0.09% | −132,448−3.8% | Reduced |
| State Street Corp | 3,422,877 | $805.5M | 0.03% | −45,438−1.3% | Reduced |
| Dodge & Cox | 3,540,262 | $833.1M | 0.48% | −82,273−2.3% | Reduced |
| Baillie Gifford & Co | 4,040,259 | $950.7M | 0.73% | −846,741−17.3% | Reduced |
| Wellington Management Group LLP | 4,196,623 | $987.5M | 0.18% | −756,724−15.3% | Reduced |
| T. Rowe Price Investment Management, Inc. | 4,384,449 | $1.03B | 0.64% | +1,245,195+39.7% | Added |
| Regeneron Pharmaceuticals, Inc. | 4,444,445 | $1.05B | 95.54% | +4,444,445 | New |
| Capital Research Global Investors | 6,968,513 | $1.64B | 0.34% | +1,724,610+32.9% | Added |
| BlackRock, Inc. | 9,885,257 | $2.33B | 0.05% | +177,839+1.8% | Added |
| Vanguard Group Inc | 12,733,399 | $3.00B | 0.05% | +98,303+0.8% | Added |
| FMR LLC | 13,485,903 | $3.17B | 0.19% | −1,186,369−8.1% | Reduced |
| Capital World Investors | 16,600,525 | $3.91B | 0.59% | +92,101+0.6% | Added |
| Fortitude Family Office, LLC | 0 | $0 | 0.00% | −14−100.0% | Sold out |
| Novo Holdings A/S | 0 | $0 | 0.00% | −118,383−100.0% | Sold out |
| Telemark Asset Management, LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | 0.00% | −73,320−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −47,193−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −35,774−100.0% | Sold out |