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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
478
0 vs. Q4 2022
Shares held
119.6M
+131.7K (+0.1%) vs. Q4 2022
Total value
$24.0B
−$4.42B (−15.6%) vs. Q4 2022
New holders
53
174 more added
Sold out
53
170 more reduced

11 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 478 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2023: $24.0B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2022.

Institutions holding ALNY in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Man Group plc–$26.3M0.09%––
Credit Suisse AG132,073$26.5M0.03%+5,994+4.8%Added
Squarepoint Ops LLC133,228$26.7M0.19%+131,019+5,931.1%Added
Eagle Health Investments LP136,756$27.4M5.33%−18,960−12.2%Reduced
State Board of Administration of Florida Retirement System137,022$27.4M0.06%−100.0%Reduced
Voloridge Investment Management, LLC141,388$28.3M0.14%−68,623−32.7%Reduced
Barclays PLC141,595$28.4M0.03%−20,539−12.7%Reduced
Tekla Capital Management LLC143,214$28.7M1.09%00.0%Unchanged
New York State Common Retirement Fund148,088$29.7M0.04%−6,610−4.3%Reduced
National Pension Service156,230$30.5M0.06%00.0%Unchanged
Two Sigma Advisers, LP155,100$31.1M0.08%+35,100+29.3%Added
Rhumbline Advisers157,895$31.6M0.04%+9,499+6.4%Added
Franklin Resources Inc160,795$32.2M0.02%−500.0%Reduced
Two Sigma Investments, LP167,346$33.5M0.10%−15,361−8.4%Reduced
Canada Pension Plan Investment Board169,198$33.9M0.05%+107,075+172.4%Added
Handelsbanken Fonder AB171,289$34.3M0.20%−21,005−10.9%Reduced
Voya Investment Management LLC172,640$34.6M0.04%−12,559−6.8%Reduced
AXA S.A.173,766$34.8M0.12%−27,650−13.7%Reduced
State of Wisconsin Investment Board182,807$36.6M0.11%+97,373+114.0%Added
Ameriprise Financial Inc203,170$40.7M0.01%+155,795+328.9%Added
California State Teachers Retirement System203,262$40.7M0.06%+1,531+0.8%Added
Assenagon Asset Management S.A.215,191$43.1M0.17%+207,364+2,649.3%Added
Royal Bank of Canada216,159$43.3M0.01%+19,579+10.0%Added
Dimensional Fund Advisors LP218,479$43.8M0.01%+23,903+12.3%Added
Goldman Sachs Group Inc230,186$46.1M0.01%−162,575−41.4%Reduced
D. E. Shaw & Co., Inc.231,345$46.3M0.07%+54,929+31.1%Added
California Public Employees Retirement System237,113$47.5M0.04%−33,770−12.5%Reduced
Wells Fargo & Company244,466$49.0M0.02%+45,050+22.6%Added
Balyasny Asset Management LLC251,798$50.4M0.17%+251,279+48,416.0%Added
Eagle Asset Management Inc263,448$52.8M0.31%−225−0.1%Reduced
Casdin Capital, LLC270,000$54.1M4.47%−95,000−26.0%Reduced
CI Private Wealth, LLC272,882$54.7M0.15%+270,010+9,401.5%Added
Janus Henderson Group PLC298,843$59.9M0.04%−166,545−35.8%Reduced
Candriam Luxembourg S.C.A.328,291$60.5M0.42%+7,796+2.4%Added
Polar Capital Holdings Plc311,918$62.5M0.46%+14,418+4.8%Added
Swedbank AB333,942$66.9M0.13%−92,711−21.7%Reduced
Manufacturers Life Insurance Company, The337,528$67.6M0.04%−5,692−1.7%Reduced
Sumitomo Mitsui Trust Holdings, Inc.340,967$68.3M0.05%+3,991+1.2%Added
Rock Springs Capital Management LP345,000$69.1M1.65%+12,500+3.8%Added
TD Asset Management Inc359,864$72.1M0.09%−32,586−8.3%Reduced
Invesco Ltd.367,375$73.6M0.02%−302,474−45.2%Reduced
Charles Schwab Investment Management Inc405,363$81.2M0.02%+4,787+1.2%Added
Mitsubishi UFJ Trust & Banking Corp407,934$81.7M0.20%−52,241−11.4%Reduced
American Century Companies Inc444,608$85.1M0.07%−255,187−36.5%Reduced
First Trust Advisors LP430,087$86.2M0.10%+9,527+2.3%Added
Deutsche Bank AG459,566$92.1M0.05%−5,487−1.2%Reduced
Swiss National Bank488,300$97.8M0.07%+2000.0%Added
Alliancebernstein L.P.535,959$107.4M0.05%+464,775+652.9%Added
Bank of New York Mellon Corp554,337$111.0M0.02%−20,048−3.5%Reduced
Pictet Asset Management SA604,075$121.0M0.15%+162,513+36.8%Added
Nuveen Asset Management, LLC609,106$122.0M0.05%−9,538−1.5%Reduced
Gilder Gagnon Howe & Co LLC621,208$124.4M2.06%−28,409−4.4%Reduced
Amundi653,780$131.3M0.07%−13,753−2.1%Reduced
Loomis Sayles & Co L P658,226$131.9M0.23%−54,330−7.6%Reduced
UBS Asset Management Americas Inc673,878$135.0M0.07%+15,958+2.4%Added
Legal & General Group Plc731,022$146.4M0.05%−1,333−0.2%Reduced
Northern Trust Corp761,584$152.6M0.03%+12,045+1.6%Added
Massachusetts Financial Services Co765,772$153.4M0.05%+10,230+1.4%Added
Bank of America Corp771,205$154.5M0.02%+467,996+154.3%Added
Bellevue Group AG883,250$176.9M2.57%−37,963−4.1%Reduced
Avoro Capital Advisors LLC1,105,000$221.4M3.28%00.0%Unchanged
Morgan Stanley1,230,815$246.6M0.03%−159,825−11.5%Reduced
Norges Bank1,521,412$304.8M0.07%+508,566+50.2%Added
RTW Investments, LP1,683,362$337.2M7.02%00.0%Unchanged
Geode Capital Management, LLC1,738,115$347.7M0.05%+48,186+2.9%Added
Capital International Investors2,229,589$446.6M0.11%+223,968+11.2%Added
Capital Research Global Investors2,439,596$488.7M0.14%+1,607,479+193.2%Added
State Street Corp2,854,881$571.9M0.03%+68,339+2.5%Added
T. Rowe Price Investment Management, Inc.3,030,821$607.1M0.44%−171,972−5.4%Reduced
JPMorgan Chase & Co3,094,734$619.9M0.08%−32,960−1.1%Reduced
Dodge & Cox3,894,535$780.2M0.53%−696,247−15.2%Reduced
Price T Rowe Associates Inc3,972,876$795.8M0.12%−101,268−2.5%Reduced
Wellington Management Group LLP6,153,777$1.23B0.24%−80,309−1.3%Reduced
BlackRock Inc.8,548,962$1.71B0.05%+59,582+0.7%Added
Baillie Gifford & Co8,639,141$1.73B1.56%−768,730−8.2%Reduced
Vanguard Group Inc11,608,167$2.33B0.06%+101,051+0.9%Added
FMR LLC13,170,835$2.64B0.24%−341,248−2.5%Reduced
Capital World Investors16,476,201$3.30B0.68%+85,926+0.5%Added
Lord, Abbett & Co. LLC0$00.00%−523,972−100.0%Sold out
Woodline Partners LP0$00.00%−95,068−100.0%Sold out
Duquesne Family Office LLCSuperinvestorDuquesne Family Office0$00.00%−88,910−100.0%Sold out
Trexquant Investment LP0$00.00%−43,673−100.0%Sold out
Nekton Capital Ltd.0$00.00%−33,890−100.0%Sold out
Bamco Inc0$00.00%−11,650−100.0%Sold out
Moore Capital Management, LP0$00.00%−10,000−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−9,892−100.0%Sold out
Moody Lynn & Lieberson, LLC0$00.00%−6,390−100.0%Sold out
Allstate Corp0$00.00%−5,228−100.0%Sold out
Endurant Capital Management LP0$00.00%−4,596−100.0%Sold out
Westwood Holdings Group Inc.0$00.00%−3,856−100.0%Sold out
Sanders Morris Harris LLC0$00.00%−3,500−100.0%Sold out
Private Advisory Group LLC0$00.00%−3,351−100.0%Sold out
Fullerton Fund Management Co Ltd.0$00.00%−2,251−100.0%Sold out
Motley Fool Asset Management LLC0$00.00%−2,181−100.0%Sold out
Fukoku Mutual Life Insurance Co0$00.00%−1,430−100.0%Sold out
First Foundation Advisors0$00.00%−1,377−100.0%Sold out
Wolverine Trading, LLC0$00.00%−1,323−100.0%Sold out
Benjamin F. Edwards & Company, Inc.0$00.00%−1,321−100.0%Sold out
HBK Sorce Advisory LLC0$00.00%−1,306−100.0%Sold out
Kula Investments, LLC0$00.00%−1,242−100.0%Sold out