Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 489
- +1 vs. Q3 2022
- Shares held
- 119.5M
- −13.5M (−10.2%) vs. Q3 2022
- Total value
- $28.4B
- +$1.76B (+6.6%) vs. Q3 2022
- New holders
- 85
- 178 more added
- Sold out
- 84
- 149 more reduced
9 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital International Ltd | 88,045 | $20.9M | 1.44% | +20,030+29.4% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 88,910 | $21.1M | 1.05% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 90,353 | $21.3M | 0.06% | +1,962+2.2% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 91,566 | $21.8M | 0.16% | −24,873−21.4% | Reduced |
| Van Eck Associates Corp | 92,380 | $22.0M | 0.06% | +22,484+32.2% | Added |
| Woodline Partners LP | 95,068 | $22.6M | 0.31% | +95,068 | New |
| Tang Capital Management LLC | 105,000 | $25.0M | 3.63% | +5,000+5.0% | Added |
| Novo Holdings A/S | 112,000 | $26.6M | 1.66% | +12,000+12.0% | Added |
| Tobam | 116,048 | $27.6M | 1.83% | +15,183+15.1% | Added |
| Jane Street Group, LLC | 118,976 | $28.3M | 0.05% | −154,013−56.4% | Reduced |
| Two Sigma Advisers, LP | 120,000 | $28.5M | 0.08% | +56,200+88.1% | Added |
| CIBC Private Wealth Group, LLC | 121,866 | $28.6M | 0.10% | +2,458+2.1% | Added |
| APG Asset Management N.V. | 125,190 | $29.8M | 0.06% | +101,998+439.8% | Added |
| HighTower Advisors, LLC | 125,742 | $29.9M | 0.07% | −1,122−0.9% | Reduced |
| Credit Suisse AG | 126,079 | $30.0M | 0.03% | +12,570+11.1% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 126,847 | $30.1M | 0.11% | +61,583+94.4% | Added |
| Aviva PLC | 129,840 | $30.9M | 0.15% | +42,365+48.4% | Added |
| Farallon Capital Management, L.L.C. | 130,056 | $30.9M | 0.20% | −298,400−69.6% | Reduced |
| State Board of Administration of Florida Retirement System | 137,032 | $32.6M | 0.08% | −1,760−1.3% | Reduced |
| Tekla Capital Management LLC | 143,214 | $34.0M | 1.29% | 00.0% | Unchanged |
| Rhumbline Advisers | 148,396 | $35.3M | 0.05% | +11,711+8.6% | Added |
| New York State Common Retirement Fund | 154,698 | $36.8M | 0.05% | +6,680+4.5% | Added |
| Eagle Health Investments LP | 155,716 | $37.0M | 8.54% | −6,000−3.7% | Reduced |
| National Pension Service | 156,230 | $37.1M | 0.07% | −757−0.5% | Reduced |
| Franklin Resources Inc | 160,845 | $38.2M | 0.02% | +1,550+1.0% | Added |
| Barclays PLC | 162,134 | $38.5M | 0.03% | +20,780+14.7% | Added |
| D. E. Shaw & Co., Inc. | 176,416 | $41.9M | 0.07% | +25,272+16.7% | Added |
| Two Sigma Investments, LP | 182,707 | $43.4M | 0.14% | −34,005−15.7% | Reduced |
| Voya Investment Management LLC | 185,199 | $44.0M | 0.05% | +99,505+116.1% | Added |
| Handelsbanken Fonder AB | 192,294 | $45.7M | 0.29% | +64,701+50.7% | Added |
| Dimensional Fund Advisors LP | 194,576 | $46.2M | 0.02% | +18,310+10.4% | Added |
| Citigroup Inc | 196,261 | $46.6M | 0.07% | +12,231+6.6% | Added |
| Royal Bank of Canada | 196,580 | $46.7M | 0.01% | +130,564+197.8% | Added |
| Wells Fargo & Company | 199,416 | $47.4M | 0.01% | +135,604+212.5% | Added |
| AXA S.A. | 201,416 | $47.9M | 0.17% | +13,576+7.2% | Added |
| California State Teachers Retirement System | 201,731 | $47.9M | 0.08% | +3,380+1.7% | Added |
| Voloridge Investment Management, LLC | 210,011 | $49.9M | 0.28% | +138,481+193.6% | Added |
| Eagle Asset Management Inc | 263,673 | $61.6M | 0.38% | +153+0.1% | Added |
| California Public Employees Retirement System | 270,883 | $64.4M | 0.05% | +1,123+0.4% | Added |
| Polar Capital Holdings Plc | 297,500 | $70.7M | 0.56% | +182,500+158.7% | Added |
| Bank of America Corp | 303,209 | $72.1M | 0.01% | +65,400+27.5% | Added |
| Candriam Luxembourg S.C.A. | 320,495 | $76.2M | 0.51% | −32,553−9.2% | Reduced |
| Rock Springs Capital Management LP | 332,500 | $79.0M | 1.90% | 00.0% | Unchanged |
| Sumitomo Mitsui Trust Holdings, Inc. | 336,976 | $80.1M | 0.06% | −1,709−0.5% | Reduced |
| Manufacturers Life Insurance Company, The | 343,220 | $81.6M | 0.05% | −567,340−62.3% | Reduced |
| Casdin Capital, LLC | 365,000 | $86.7M | 6.77% | −283,000−43.7% | Reduced |
| 1832 Asset Management L.P. | 391,345 | $93.0M | 0.19% | +4,200+1.1% | Added |
| TD Asset Management Inc | 392,450 | $93.3M | 0.12% | +7,639+2.0% | Added |
| Goldman Sachs Group Inc | 392,761 | $93.3M | 0.03% | −72,546−15.6% | Reduced |
| Charles Schwab Investment Management Inc | 400,576 | $95.2M | 0.03% | +21,711+5.7% | Added |
| First Trust Advisors LP | 420,560 | $99.9M | 0.12% | −74,372−15.0% | Reduced |
| Swedbank AB | 426,653 | $101.4M | 0.22% | +10,593+2.5% | Added |
| Pictet Asset Management SA | 441,562 | $104.9M | 0.15% | −234,247−34.7% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 460,175 | $109.4M | 0.29% | −14,473−3.0% | Reduced |
| Deutsche Bank AG | 465,053 | $110.5M | 0.06% | +211,369+83.3% | Added |
| Janus Henderson Group PLC | 465,388 | $110.6M | 0.08% | −109,116−19.0% | Reduced |
| Swiss National Bank | 488,100 | $116.0M | 0.08% | −35,510−6.8% | Reduced |
| Lord, Abbett & Co. LLC | 523,972 | $124.5M | 0.44% | +4,840+0.9% | Added |
| Bank of New York Mellon Corp | 574,385 | $136.5M | 0.03% | +7,247+1.3% | Added |
| Holocene Advisors, LP | 598,928 | $142.3M | 0.88% | −44,721−6.9% | Reduced |
| Nuveen Asset Management, LLC | 618,644 | $147.0M | 0.06% | −15,974,624−96.3% | Reduced |
| Amundi | 667,533 | $150.3M | 0.08% | −528,376−44.2% | Reduced |
| Gilder Gagnon Howe & Co LLC | 649,617 | $154.4M | 2.88% | −14,366−2.2% | Reduced |
| UBS Asset Management Americas Inc | 657,920 | $156.4M | 0.08% | +54,388+9.0% | Added |
| Invesco Ltd. | 669,849 | $159.2M | 0.05% | −67,981−9.2% | Reduced |
| American Century Companies Inc | 699,795 | $166.3M | 0.14% | +6,788+1.0% | Added |
| Loomis Sayles & Co L P | 712,556 | $169.3M | 0.34% | −35,194−4.7% | Reduced |
| Legal & General Group Plc | 732,355 | $174.0M | 0.07% | −22,137−2.9% | Reduced |
| Northern Trust Corp | 749,539 | $178.1M | 0.04% | +15,547+2.1% | Added |
| Massachusetts Financial Services Co | 755,542 | $179.6M | 0.06% | +219,943+41.1% | Added |
| Capital Research Global Investors | 832,117 | $197.8M | 0.06% | +832,117 | New |
| Bellevue Group AG | 921,213 | $218.9M | 2.91% | −35,549−3.7% | Reduced |
| Norges Bank | 1,012,846 | $240.7M | 0.06% | −205,338−16.9% | Reduced |
| Avoro Capital Advisors LLC | 1,105,000 | $262.6M | 3.92% | 00.0% | Unchanged |
| Morgan Stanley | 1,390,640 | $330.5M | 0.04% | −108,119−7.2% | Reduced |
| RTW Investments, LP | 1,683,362 | $400.1M | 8.17% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,689,929 | $401.1M | 0.06% | +90,455+5.7% | Added |
| Capital International Investors | 2,005,621 | $476.6M | 0.13% | +58,907+3.0% | Added |
| State Street Corp | 2,786,542 | $662.2M | 0.04% | −8,943−0.3% | Reduced |
| JPMorgan Chase & Co | 3,127,694 | $743.3M | 0.11% | +582,662+22.9% | Added |
| T. Rowe Price Investment Management, Inc. | 3,202,793 | $761.1M | 0.58% | +10,609+0.3% | Added |
| Price T Rowe Associates Inc | 4,074,144 | $968.2M | 0.16% | +353,538+9.5% | Added |
| Dodge & Cox | 4,590,782 | $1.09B | 0.75% | −298,515−6.1% | Reduced |
| Wellington Management Group LLP | 6,234,086 | $1.48B | 0.30% | +279,793+4.7% | Added |
| BlackRock Inc. | 8,489,380 | $2.02B | 0.06% | +820,702+10.7% | Added |
| Baillie Gifford & Co | 9,407,871 | $2.24B | 2.33% | −106,887−1.1% | Reduced |
| Vanguard Group Inc | 11,507,116 | $2.73B | 0.07% | +453,808+4.1% | Added |
| FMR LLC | 13,512,083 | $3.21B | 0.32% | +562,325+4.3% | Added |
| Capital World Investors | 16,390,275 | $3.90B | 0.83% | +2,440,628+17.5% | Added |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −485,000−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −288,500−100.0% | Sold out |
| OrbiMed Advisors LLC | 0 | $0 | 0.00% | −250,500−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −226,034−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −172,770−100.0% | Sold out |
| Senator Investment Group LP | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Bessemer Group Inc | 0 | $0 | 0.00% | −84,280−100.0% | Sold out |
| Iron Triangle Partners LP | 0 | $0 | 0.00% | −80,000−100.0% | Sold out |
| Twin Tree Management, LP | 0 | $0 | 0.00% | −72,861−100.0% | Sold out |
| Putnam Investments LLC | 0 | $0 | 0.00% | −72,194−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −44,547−100.0% | Sold out |