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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
435
+36 vs. Q3 2021
Shares held
112.1M
+547.7K (+0.5%) vs. Q3 2021
Total value
$19.0B
−$2.05B (−9.7%) vs. Q3 2021
New holders
77
156 more added
Sold out
41
132 more reduced

8 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 435 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2021: $19.0B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding ALNY in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Blackstone Group Inc.517,391$87.7M0.22%00.0%Unchanged
Polar Capital Holdings Plc535,631$90.8M0.47%+11,919+2.3%Added
Nuveen Asset Management, LLC590,544$100.1M0.03%−176,488−23.0%Reduced
Bank of New York Mellon Corp602,314$102.1M0.02%+149,064+32.9%Added
Pictet Asset Management SA613,992$104.1M0.10%−209,712−25.5%Reduced
UBS Asset Management Americas Inc640,710$108.7M0.04%−4,862−0.8%Reduced
Artal Group S.A.650,000$110.2M3.24%−50,000−7.1%Reduced
Legal & General Group Plc679,570$115.2M0.03%+12,785+1.9%Added
Goldman Sachs Group Inc686,695$116.5M0.03%+20,240+3.0%Added
Holocene Advisors, LP722,739$122.6M0.65%+61,509+9.3%Added
Northern Trust Corp769,413$130.5M0.02%−9,708−1.2%Reduced
Gilder Gagnon Howe & Co LLC839,568$142.4M0.81%−84,116−9.1%Reduced
Invesco Ltd.890,090$150.9M0.04%−164,082−15.6%Reduced
Federated Hermes, Inc.992,180$168.3M0.31%+33,360+3.5%Added
Loomis Sayles & Co L P996,437$169.0M0.20%+28,330+2.9%Added
Casdin Capital, LLC1,000,000$169.6M4.78%00.0%Unchanged
American Century Companies Inc1,002,574$170.0M0.11%−68,897−6.4%Reduced
Morgan Stanley1,065,689$180.7M0.02%−815,190−43.3%Reduced
Avoro Capital Advisors LLC1,075,000$182.3M3.10%+225,000+26.5%Added
Farallon Capital Management, L.L.C.1,190,028$201.8M1.14%+375,727+46.1%Added
Norges Bank1,269,191$215.2M0.04%+274,303+27.6%Added
Massachusetts Financial Services Co1,322,211$224.2M0.06%−43,076−3.2%Reduced
Bellevue Group AG1,335,140$226.4M2.33%−73,278−5.2%Reduced
Geode Capital Management, LLC1,505,291$254.9M0.03%+51,272+3.5%Added
Manufacturers Life Insurance Company, The1,702,670$289.1M0.18%−28,763−1.7%Reduced
RTW Investments, LP1,975,879$335.1M4.89%+292,517+17.4%Added
State Street Corp2,850,389$483.4M0.02%+49,564+1.8%Added
JPMorgan Chase & Co2,972,085$504.0M0.06%+526,426+21.5%Added
Dodge & Cox5,431,068$921.0M0.57%+58,968+1.1%Added
Price T Rowe Associates Inc6,535,368$1.11B0.10%+661,133+11.3%Added
Wellington Management Group LLP6,844,430$1.16B0.19%−526,642−7.1%Reduced
BlackRock Inc.7,671,402$1.30B0.03%−1,249,570−14.0%Reduced
Baillie Gifford & Co10,616,751$1.80B0.99%+200,967+1.9%Added
Vanguard Group Inc10,702,771$1.81B0.04%+88,189+0.8%Added
FMR LLC17,940,020$3.04B0.22%+113,092+0.6%Added
Alkeon Capital Management LLC0$00.00%−390,551−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−99,512−100.0%Sold out
Atika Capital Management LLC0$00.00%−64,000−100.0%Sold out
Bridger Management, LLC0$00.00%−59,804−100.0%Sold out
NN Investment Partners Holdings N.V.0$00.00%−31,296−100.0%Sold out
HRT Financial LP0$00.00%−30,777−100.0%Sold out
Ararat Capital Management, LP0$00.00%−28,985−100.0%Sold out
AMP Capital Investors Ltd0$00.00%−25,424−100.0%Sold out
Marshall Wace, LLP0$00.00%−16,427−100.0%Sold out
Simplex Trading, LLC0$00.00%−15,991−100.0%Sold out
Quantitative Investment Management, LLC0$00.00%−14,293−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−12,506−100.0%Sold out
Caption Management, LLC0$00.00%−7,800−100.0%Sold out
HealthCor Management, L.P.0$00.00%−7,510−100.0%Sold out
Bradley Foster & Sargent Inc0$00.00%−5,223−100.0%Sold out
Meeder Asset Management Inc0$00.00%−5,104−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−4,755−100.0%Sold out
Maverick Capital LtdSuperinvestorMaverick Capital0$00.00%−3,983−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−3,900−100.0%Sold out
Northstar Advisory Group, LLC0$00.00%−3,635−100.0%Sold out
Man Group plc0$00.00%−3,443−100.0%Sold out
Winton Group Ltd0$00.00%−2,911−100.0%Sold out
Bridgewater Associates, LP0$00.00%−2,234−100.0%Sold out
FORA Capital, LLC0$00.00%−2,229−100.0%Sold out
Global Retirement Partners, LLC0$00.00%−2,034−100.0%Sold out
Centiva Capital, LP0$00.00%−1,731−100.0%Sold out
Paloma Partners Management Co0$00.00%−1,697−100.0%Sold out
Meristem Family Wealth, LLC0$00.00%−1,344−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−1,300−100.0%Sold out
Phoenix Holdings Ltd.0$00.00%−1,296−100.0%Sold out
Laurel Wealth Advisors, Inc.0$00.00%−1,137−100.0%Sold out
Ethic Inc.0$00.00%−1,122−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−220−100.0%Sold out
Bessemer Group Inc0$00.00%−39−100.0%Sold out
Carroll Financial Associates, Inc.0$00.00%−41−100.0%Sold out
Meridian Wealth Partners, LLC0$00.00%−24−100.0%Sold out
Asset Dedication, LLC0$00.00%−16−100.0%Sold out
Farmers & Merchants Investments Inc0$00.00%−4−100.0%Sold out
Cordant, Inc.0$00.00%−4−100.0%Sold out
Better Money Decisions, LLC0$00.00%−7−100.0%Sold out
Gerber Kawasaki Wealth & Investment Management0$00.00%−2−100.0%Sold out
Alexandria Capital, LLC––––Not filed
NorthCoast Asset Management LLC––––Not filed
B. Metzler seel. Sohn & Co. Holding AG––––Not filed
World Asset Management Inc––––Not filed
Green Harvest Asset Management LLC––––Not filed
Berman Capital Advisors, LLC––––Not filed
Towarzystwo Funduszy Inwestycyjnych Pzu SA––––Not filed
Psagot Investment House Ltd.––––Not filed