Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2025 年第 4 季 13F 持有人
Denali Therapeutics Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 250
- 較 2025 年第 3 季 +17 家
- 持有股數
- 1.51 億
- 較 2025 年第 3 季 +1,619 萬 (+12.0%)
- 總市值
- $25.0 億
- 較 2025 年第 3 季 +$5.36 億 (+27.4%)
- 新進機構
- 51
- 另有 86 家加碼
- 清倉機構
- 34
- 另有 71 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2025 年第 4 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| SBI Okasan Asset Management Co.Ltd. | 18,000 | $29.8 萬 | 0.02% | +18,000 | 新進 |
| Graham Capital Management, L.P. | 18,121 | $29.9 萬 | 0.01% | −21,198−53.9% | 減碼 |
| Martingale Asset Management L P | 18,535 | $30.6 萬 | 0.01% | +18,535 | 新進 |
| Bayforest Capital Ltd | 20,433 | $33.7 萬 | 0.25% | +20,433 | 新進 |
| Teacher Retirement System of Texas | 20,540 | $33.9 萬 | 0.00% | −13,287−39.3% | 減碼 |
| TT International Asset Management LTD | 27,000 | $35.3 萬 | 0.07% | −38,000−58.5% | 減碼 |
| Voya Investment Management LLC | 23,805 | $39.3 萬 | 0.00% | 00.0% | 不變 |
| China Universal Asset Management Co., Ltd. | 23,898 | $39.5 萬 | 0.03% | −1,731−6.8% | 減碼 |
| Raymond James Financial Inc | 25,592 | $42.3 萬 | 0.00% | +266+1.1% | 加碼 |
| Quantinno Capital Management LP | 26,313 | $43.4 萬 | 0.00% | +1,606+6.5% | 加碼 |
| Polen Capital Management LLC | 26,900 | $44.4 萬 | 0.00% | +26,900 | 新進 |
| Erste Asset Management GmbH | 26,900 | $44.6 萬 | 0.00% | 00.0% | 不變 |
| KLP Kapitalforvaltning AS | 29,900 | $49.4 萬 | 0.00% | 00.0% | 不變 |
| ProShare Advisors LLC | 30,682 | $50.7 萬 | 0.00% | +2,827+10.1% | 加碼 |
| Citigroup Inc | 30,945 | $51.1 萬 | 0.00% | +16,009+107.2% | 加碼 |
| PSP Research LLC | 31,762 | $52.4 萬 | 0.46% | +31,762 | 新進 |
| Thrivent Financial for Lutherans | 32,555 | $53.8 萬 | 0.00% | −3,064−8.6% | 減碼 |
| State Board of Administration of Florida Retirement System | 34,168 | $56.4 萬 | 0.00% | 00.0% | 不變 |
| Susquehanna International Group, LLP | 34,768 | $57.4 萬 | 0.00% | −6,218−15.2% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 36,607 | $60.4 萬 | 0.01% | −56−0.2% | 減碼 |
| AQR Capital Management LLC | 38,438 | $63.5 萬 | 0.00% | +14,299+59.2% | 加碼 |
| New York State Common Retirement Fund | 38,478 | $63.5 萬 | 0.00% | 00.0% | 不變 |
| Arizona State Retirement System | 38,645 | $63.8 萬 | 0.00% | −2,168−5.3% | 減碼 |
| Envestnet Asset Management Inc | 38,669 | $63.8 萬 | 0.00% | +6,254+19.3% | 加碼 |
| Capstone Investment Advisors, LLC | 38,812 | $64.1 萬 | 0.01% | +38,812 | 新進 |
| Savvy Advisors, Inc. | 39,030 | $64.4 萬 | 0.02% | −38,063−49.4% | 減碼 |
| Jump Financial, LLC | 40,608 | $67.0 萬 | 0.01% | −125,791−75.6% | 減碼 |
| Quest Partners LLC | 42,909 | $70.8 萬 | 0.04% | −31,513−42.3% | 減碼 |
| Jane Street Group, LLC | 42,922 | $70.9 萬 | 0.00% | −181,981−80.9% | 減碼 |
| Handelsbanken Fonder AB | 43,800 | $72.3 萬 | 0.00% | +5,500+14.4% | 加碼 |
| Headlands Technologies LLC | 46,383 | $76.6 萬 | 0.06% | +46,383 | 新進 |
| MAI Capital Management | 46,526 | $76.8 萬 | 0.00% | 00.0% | 不變 |
| Employees Retirement System of Texas | 47,177 | $77.9 萬 | 0.01% | +3,408+7.8% | 加碼 |
| State of New Jersey Common Pension Fund D | 47,410 | $78.3 萬 | 0.00% | −92,253−66.1% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 47,459 | $78.4 萬 | 0.00% | 00.0% | 不變 |
| Man Group plc | 48,994 | $80.9 萬 | 0.00% | +48,994 | 新進 |
| Knights of Columbus Asset Advisors LLC | 49,007 | $80.9 萬 | 0.05% | −1,183−2.4% | 減碼 |
| Dana Investment Advisors, Inc. | 50,582 | $83.5 萬 | 0.02% | −134−0.3% | 減碼 |
| Ironwood Investment Management LLC | 50,933 | $84.1 萬 | 0.35% | −1,853−3.5% | 減碼 |
| Pathstone Holdings, LLC | 51,424 | $84.9 萬 | 0.00% | +5,594+12.2% | 加碼 |
| Clough Capital Partners L P | 51,830 | $85.6 萬 | 0.08% | +51,830 | 新進 |
| ADAR1 Capital Management, LLC | 52,116 | $86.0 萬 | 0.06% | +600+1.2% | 加碼 |
| Intech Investment Management LLC | 52,632 | $86.9 萬 | 0.01% | +5,835+12.5% | 加碼 |
| Tudor Investment Corp Et Al | 53,683 | $88.6 萬 | 0.00% | −2,685−4.8% | 減碼 |
| Wellington Management Group LLP | 54,543 | $90.1 萬 | 0.00% | −4,691−7.9% | 減碼 |
| Janus Henderson Group PLC | 60,028 | $99.1 萬 | 0.00% | 00.0% | 不變 |
| Franklin Resources Inc | 60,270 | $99.5 萬 | 0.00% | −4,364−6.8% | 減碼 |
| Creative Planning | 60,766 | $100.3 萬 | 0.00% | +5,932+10.8% | 加碼 |
| Capricorn Fund Managers Ltd | 62,197 | $102.7 萬 | 0.25% | +62,197 | 新進 |
| 1492 Capital Management LLC | 67,487 | $111.4 萬 | 0.43% | +67,487 | 新進 |
| Pier 88 Investment Partners LLC | 68,200 | $112.6 萬 | 0.25% | +760+1.1% | 加碼 |
| Ishara Investments LP | 70,000 | $115.6 萬 | 1.35% | +70,000 | 新進 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 70,830 | $116.9 萬 | 0.00% | +44,607+170.1% | 加碼 |
| Profund Advisors LLC | 71,634 | $118.3 萬 | 0.04% | +31,478+78.4% | 加碼 |
| State of Wisconsin Investment Board | 73,581 | $121.5 萬 | 0.00% | −6,545−8.2% | 減碼 |
| MetLife Investment Management | 75,164 | $124.1 萬 | 0.01% | −3,911−4.9% | 減碼 |
| HRT Financial LP | 78,352 | $129.3 萬 | 0.00% | +78,352 | 新進 |
| DekaBank Deutsche Girozentrale | 59,800 | $135.0 萬 | 0.00% | 00.0% | 不變 |
| Monashee Investment Management LLC | 91,620 | $151.3 萬 | 0.85% | +91,620 | 新進 |
| Y-Intercept (Hong Kong) Ltd | 93,587 | $154.5 萬 | 0.03% | +93,587 | 新進 |
| Integrated Wealth Concepts LLC | 94,582 | $156.2 萬 | 0.02% | +3,508+3.9% | 加碼 |
| Rhenman & Partners Asset Management AB | 100,000 | $165.1 萬 | 0.15% | 00.0% | 不變 |
| Ghisallo Capital Management LLC | 100,000 | $165.1 萬 | 0.07% | +100,000 | 新進 |
| Deutsche Bank AG | 105,086 | $173.5 萬 | 0.00% | −102,508−49.4% | 減碼 |
| D.A. Davidson & Co. | 106,933 | $176.5 萬 | 0.01% | +106,933 | 新進 |
| Nomura Asset Management International Inc. | 107,493 | $177.5 萬 | 0.00% | +107,493 | 新進 |
| B. Metzler seel. Sohn & Co. AG | 112,300 | $184.1 萬 | 0.02% | +112,300 | 新進 |
| Woodline Partners LP | 114,082 | $188.3 萬 | 0.01% | +565+0.5% | 加碼 |
| Alps Advisors Inc | 120,718 | $199.3 萬 | 0.01% | +50,488+71.9% | 加碼 |
| Algert Global LLC | 127,030 | $209.7 萬 | 0.03% | +25,770+25.4% | 加碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 128,800 | $212.5 萬 | 0.00% | −1,087−0.8% | 減碼 |
| California State Teachers Retirement System | 129,409 | $213.7 萬 | 0.00% | −117−0.1% | 減碼 |
| Legal & General Group Plc | 131,223 | $216.6 萬 | 0.00% | −12,729−8.8% | 減碼 |
| SG Americas Securities, LLC | 149,592 | $247.0 萬 | 0.00% | +111,391+291.6% | 加碼 |
| Groupama Asset Managment | 151,591 | $250.3 萬 | 0.04% | +15,833+11.7% | 加碼 |
| Teachers Retirement System of the State of Kentucky | 153,781 | $253.9 萬 | 0.02% | −17,772−10.4% | 減碼 |
| Two Sigma Advisers, LP | 154,800 | $255.6 萬 | 0.00% | +64,800+72.0% | 加碼 |
| Susquehanna Portfolio Strategies, LLC | 167,713 | $276.9 萬 | 0.04% | +167,713 | 新進 |
| JPMorgan Chase & Co | 171,948 | $283.9 萬 | 0.00% | −3,073−1.8% | 減碼 |
| Ameriprise Financial Inc | 180,221 | $297.5 萬 | 0.00% | +80,660+81.0% | 加碼 |
| Rhumbline Advisers | 183,000 | $302.1 萬 | 0.00% | −18,565−9.2% | 減碼 |
| Manufacturers Life Insurance Company, The | 184,238 | $303.0 萬 | 0.00% | −21,607−10.5% | 減碼 |
| Rafferty Asset Management, LLC | 191,567 | $316.3 萬 | 0.01% | +8,681+4.7% | 加碼 |
| Wells Fargo & Company | 193,681 | $319.8 萬 | 0.00% | +89,502+85.9% | 加碼 |
| SCS Capital Management LLC | 197,998 | $326.9 萬 | 0.03% | 00.0% | 不變 |
| Burkehill Global Management, LP | 200,000 | $330.2 萬 | 0.22% | +200,000 | 新進 |
| Trexquant Investment LP | 209,609 | $346.1 萬 | 0.03% | −220,957−51.3% | 減碼 |
| Edmond de Rothschild Holding S.A. | 225,680 | $372.6 萬 | 0.05% | +20,000+9.7% | 加碼 |
| Swiss National Bank | 273,800 | $452.0 萬 | 0.00% | +6,300+2.4% | 加碼 |
| Nuveen, LLC | 275,508 | $454.9 萬 | 0.00% | −9,269−3.3% | 減碼 |
| Marex Group plc | 287,001 | $473.8 萬 | 0.05% | −3,999−1.4% | 減碼 |
| Invesco Ltd. | 291,936 | $482.0 萬 | 0.00% | +42,469+17.0% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 298,792 | $493.3 萬 | 0.01% | +297,521+23,408.4% | 加碼 |
| DAFNA Capital Management LLC | 318,500 | $525.8 萬 | 1.22% | +150,000+89.0% | 加碼 |
| TD Asset Management Inc | 339,410 | $560.4 萬 | 0.00% | −55,190−14.0% | 減碼 |
| Clarius Group, LLC | 368,995 | $609.2 萬 | 0.35% | +9,250+2.6% | 加碼 |
| Millennium Management LLC | 369,767 | $610.5 萬 | 0.00% | −937,404−71.7% | 減碼 |
| American Century Companies Inc | 379,051 | $625.8 萬 | 0.00% | +21,710+6.1% | 加碼 |
| Barclays PLC | 407,359 | $672.5 萬 | 0.00% | −29,642−6.8% | 減碼 |
| StemPoint Capital LP | 419,058 | $691.9 萬 | 1.19% | −1,315,601−75.8% | 減碼 |