Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2025 年第 3 季 13F 持有人
Denali Therapeutics Inc. 在 2025/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 240
- 較 2025 年第 2 季 +13 家
- 持有股數
- 1.35 億
- 較 2025 年第 2 季 +228.0 萬 (+1.7%)
- 總市值
- $19.7 億
- 較 2025 年第 2 季 +$1.04 億 (+5.6%)
- 新進機構
- 35
- 另有 91 家加碼
- 清倉機構
- 22
- 另有 67 家減碼
另有 4 家機構在 2025 年第 2 季持有、還沒有申報 2025 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2025 年第 3 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Quantinno Capital Management LP | 24,707 | $35.9 萬 | 0.00% | +24,707 | 新進 |
| Raymond James Financial Inc | 25,326 | $36.8 萬 | 0.00% | −1,270−4.8% | 減碼 |
| China Universal Asset Management Co., Ltd. | 25,629 | $37.2 萬 | 0.03% | −3,549−12.2% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 26,223 | $38.1 萬 | 0.00% | +4,739+22.1% | 加碼 |
| Erste Asset Management GmbH | 26,900 | $39.1 萬 | 0.00% | 00.0% | 不變 |
| Cinctive Capital Management LP | 27,792 | $40.4 萬 | 0.02% | +3,482+14.3% | 加碼 |
| ProShare Advisors LLC | 27,855 | $40.4 萬 | 0.00% | −4,727−14.5% | 減碼 |
| KLP Kapitalforvaltning AS | 29,900 | $43.4 萬 | 0.00% | +3,800+14.6% | 加碼 |
| Envestnet Asset Management Inc | 32,415 | $47.1 萬 | 0.00% | −1,123−3.3% | 減碼 |
| Teacher Retirement System of Texas | 33,827 | $49.1 萬 | 0.00% | −1,394−4.0% | 減碼 |
| State Board of Administration of Florida Retirement System | 34,168 | $49.6 萬 | 0.00% | 00.0% | 不變 |
| Thrivent Financial for Lutherans | 35,619 | $51.7 萬 | 0.00% | −32,298−47.6% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 36,663 | $53.2 萬 | 0.00% | +6,269+20.6% | 加碼 |
| SG Americas Securities, LLC | 38,201 | $55.5 萬 | 0.00% | +38,201 | 新進 |
| Handelsbanken Fonder AB | 38,300 | $55.6 萬 | 0.00% | 00.0% | 不變 |
| New York State Common Retirement Fund | 38,478 | $55.9 萬 | 0.00% | 00.0% | 不變 |
| Graham Capital Management, L.P. | 39,319 | $57.1 萬 | 0.02% | −25,480−39.3% | 減碼 |
| Profund Advisors LLC | 40,156 | $58.3 萬 | 0.02% | +13,433+50.3% | 加碼 |
| Arizona State Retirement System | 40,813 | $59.3 萬 | 0.00% | +2,699+7.1% | 加碼 |
| Susquehanna International Group, LLP | 40,986 | $59.5 萬 | 0.00% | −120,150−74.6% | 減碼 |
| Employees Retirement System of Texas | 43,769 | $63.6 萬 | 0.01% | 00.0% | 不變 |
| Cantor Fitzgerald, L. P. | 45,000 | $65.3 萬 | 0.01% | +45,000 | 新進 |
| Jennison Associates LLC | 45,445 | $66.0 萬 | 0.00% | +45,445 | 新進 |
| Pathstone Holdings, LLC | 45,830 | $66.5 萬 | 0.00% | +790+1.8% | 加碼 |
| Jacobs Levy Equity Management, Inc | 45,969 | $66.7 萬 | 0.00% | +45,969 | 新進 |
| MAI Capital Management | 46,526 | $67.6 萬 | 0.00% | 00.0% | 不變 |
| Intech Investment Management LLC | 46,797 | $67.9 萬 | 0.01% | −25,069−34.9% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 47,459 | $68.9 萬 | 0.00% | +3,872+8.9% | 加碼 |
| Guggenheim Capital LLC | 49,525 | $71.9 萬 | 0.01% | −2,335−4.5% | 減碼 |
| Knights of Columbus Asset Advisors LLC | 50,190 | $72.9 萬 | 0.04% | +11,711+30.4% | 加碼 |
| Dana Investment Advisors, Inc. | 50,716 | $73.6 萬 | 0.02% | +15,155+42.6% | 加碼 |
| ADAR1 Capital Management, LLC | 51,516 | $74.8 萬 | 0.07% | +15,800+44.2% | 加碼 |
| Ironwood Investment Management LLC | 52,786 | $76.6 萬 | 0.33% | −426−0.8% | 減碼 |
| Creative Planning | 54,834 | $79.6 萬 | 0.00% | −2,844−4.9% | 減碼 |
| Aquatic Capital Management LLC | 56,237 | $81.7 萬 | 0.02% | +56,237 | 新進 |
| Tudor Investment Corp Et Al | 56,368 | $81.8 萬 | 0.01% | +920+1.7% | 加碼 |
| Wellington Management Group LLP | 59,234 | $86.0 萬 | 0.00% | −5,605,499−99.0% | 減碼 |
| DekaBank Deutsche Girozentrale | 59,800 | $86.4 萬 | 0.00% | 00.0% | 不變 |
| Renaissance Technologies LLC | 59,800 | $86.8 萬 | 0.00% | −135,900−69.4% | 減碼 |
| Janus Henderson Group PLC | 60,028 | $87.2 萬 | 0.00% | 00.0% | 不變 |
| Franklin Resources Inc | 64,634 | $93.8 萬 | 0.00% | +109+0.2% | 加碼 |
| TT International Asset Management LTD | 65,000 | $94.4 萬 | 0.18% | 00.0% | 不變 |
| XTX Topco Ltd | 65,345 | $94.9 萬 | 0.05% | +65,345 | 新進 |
| Pier 88 Investment Partners LLC | 67,440 | $97.9 萬 | 0.18% | +10,290+18.0% | 加碼 |
| Engineers Gate Manager LP | 69,216 | $100.5 萬 | 0.01% | −46,885−40.4% | 減碼 |
| Alps Advisors Inc | 70,230 | $102.0 萬 | 0.01% | −8,126−10.4% | 減碼 |
| Quest Partners LLC | 74,422 | $108.1 萬 | 0.07% | +51,458+224.1% | 加碼 |
| Savvy Advisors, Inc. | 77,093 | $111.9 萬 | 0.05% | −20,700−21.2% | 減碼 |
| MetLife Investment Management | 79,075 | $114.8 萬 | 0.01% | 00.0% | 不變 |
| State of Wisconsin Investment Board | 80,126 | $116.3 萬 | 0.00% | +499+0.6% | 加碼 |
| Squarepoint Ops LLC | 80,518 | $116.9 萬 | 0.00% | +80,518 | 新進 |
| Two Sigma Advisers, LP | 90,000 | $130.7 萬 | 0.00% | +62,400+226.1% | 加碼 |
| Integrated Wealth Concepts LLC | 91,074 | $132.2 萬 | 0.01% | −4,972−5.2% | 減碼 |
| Ameriprise Financial Inc | 99,561 | $144.6 萬 | 0.00% | −2,472−2.4% | 減碼 |
| Rhenman & Partners Asset Management AB | 100,000 | $145.2 萬 | 0.16% | 00.0% | 不變 |
| Algert Global LLC | 101,260 | $147.0 萬 | 0.02% | +15,420+18.0% | 加碼 |
| Wells Fargo & Company | 104,179 | $151.3 萬 | 0.00% | +14,540+16.2% | 加碼 |
| Woodline Partners LP | 113,517 | $164.8 萬 | 0.01% | 00.0% | 不變 |
| Edgestream Partners, L.P. | 123,819 | $179.8 萬 | 0.05% | −219,104−63.9% | 減碼 |
| California State Teachers Retirement System | 129,526 | $188.1 萬 | 0.00% | +10,199+8.5% | 加碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 129,887 | $188.6 萬 | 0.00% | −4,816−3.6% | 減碼 |
| Groupama Asset Managment | 135,758 | $197.1 萬 | 0.03% | −39,773−22.7% | 減碼 |
| State of New Jersey Common Pension Fund D | 139,663 | $202.8 萬 | 0.01% | +1,783+1.3% | 加碼 |
| Legal & General Group Plc | 143,952 | $209.0 萬 | 0.00% | +12,197+9.3% | 加碼 |
| Jump Financial, LLC | 166,399 | $241.6 萬 | 0.03% | +166,399 | 新進 |
| DAFNA Capital Management LLC | 168,500 | $244.7 萬 | 0.60% | 00.0% | 不變 |
| Teachers Retirement System of the State of Kentucky | 171,553 | $249.1 萬 | 0.02% | 00.0% | 不變 |
| JPMorgan Chase & Co | 175,021 | $254.1 萬 | 0.00% | −16,592−8.7% | 減碼 |
| Rafferty Asset Management, LLC | 182,886 | $265.6 萬 | 0.01% | +60,624+49.6% | 加碼 |
| SCS Capital Management LLC | 197,998 | $287.5 萬 | 0.03% | 00.0% | 不變 |
| Rhumbline Advisers | 201,565 | $292.7 萬 | 0.00% | −10,938−5.1% | 減碼 |
| Edmond de Rothschild Holding S.A. | 205,680 | $298.6 萬 | 0.05% | 00.0% | 不變 |
| Manufacturers Life Insurance Company, The | 205,845 | $298.9 萬 | 0.00% | −109,257−34.7% | 減碼 |
| Deutsche Bank AG | 207,594 | $301.4 萬 | 0.00% | +71,625+52.7% | 加碼 |
| Schroder Investment Management Group | 209,595 | $304.3 萬 | 0.00% | −176,944−45.8% | 減碼 |
| Campbell & CO Investment Adviser LLC | 216,774 | $314.8 萬 | 0.24% | +74,066+51.9% | 加碼 |
| Jane Street Group, LLC | 224,903 | $326.6 萬 | 0.00% | +139,571+163.6% | 加碼 |
| Schonfeld Strategic Advisors LLC | 226,203 | $328.4 萬 | 0.02% | +226,203 | 新進 |
| Qube Research & Technologies Ltd | 227,990 | $331.0 萬 | 0.00% | +227,990 | 新進 |
| Cubist Systematic Strategies, LLC | 230,968 | $335.4 萬 | 0.05% | −165,618−41.8% | 減碼 |
| Invesco Ltd. | 249,467 | $362.2 萬 | 0.00% | +29,672+13.5% | 加碼 |
| Boxer Capital Management, LLC | 250,000 | $363.0 萬 | 1.16% | +250,000 | 新進 |
| Lynx1 Capital Management LP | 261,687 | $380.0 萬 | 0.77% | +261,687 | 新進 |
| BNP Paribas Arbitrage, SA | 264,061 | $383.4 萬 | 0.00% | +244,979+1,283.8% | 加碼 |
| Two Sigma Investments, LP | 266,292 | $386.7 萬 | 0.01% | +246,992+1,279.8% | 加碼 |
| Swiss National Bank | 267,500 | $388.4 萬 | 0.00% | +16,600+6.6% | 加碼 |
| Nuveen, LLC | 284,777 | $413.5 萬 | 0.00% | −310,440−52.2% | 減碼 |
| Marex Group plc | 291,000 | $422.5 萬 | 0.05% | +29,000+11.1% | 加碼 |
| AXA Investment Managers S.A. | 294,732 | $428.0 萬 | 0.01% | +294,732 | 新進 |
| Pier Capital, LLC | 301,171 | $437.3 萬 | 0.68% | −13,625−4.3% | 減碼 |
| Hudson Bay Capital Management LP | 305,000 | $442.9 萬 | 0.03% | +15,000+5.2% | 加碼 |
| American Century Companies Inc | 357,341 | $518.9 萬 | 0.00% | +39,148+12.3% | 加碼 |
| Clarius Group, LLC | 359,745 | $522.3 萬 | 0.31% | −9,250−2.5% | 減碼 |
| Royal Bank of Canada | 372,176 | $540.4 萬 | 0.00% | −17,979−4.6% | 減碼 |
| TD Asset Management Inc | 394,600 | $573.0 萬 | 0.00% | −101,690−20.5% | 減碼 |
| Palo Alto Investors LP | 408,006 | $592.4 萬 | 1.10% | +168,197+70.1% | 加碼 |
| Trexquant Investment LP | 430,566 | $625.2 萬 | 0.06% | +321,324+294.1% | 加碼 |
| Barclays PLC | 437,001 | $634.5 萬 | 0.00% | +11,020+2.6% | 加碼 |
| Yiheng Capital Management, L.P. | 469,981 | $682.4 萬 | 2.26% | 00.0% | 不變 |
| Pictet Asset Management Holding SA | 499,162 | $724.8 萬 | 0.01% | +84,050+20.2% | 加碼 |