Apellis Pharmaceuticals, Inc.

APLS2026/5/14 下市

產業: Pharmaceutical Preparations
SEC CIK: 0001492422

SEC 申報列表（在新分頁開啟）

Apellis Pharmaceuticals, Inc. 已在 2026/5/14 下市；內部人最後一份 Form 4 在 2026/5/14 申報；2026 年第 1 季末有 324 家機構在 13F 申報持有，市值合計 $55.6 億；大師中只有索羅斯基金管理持有。

2026 年第 1 季與 2025 年第 4 季比較

持有 Apellis Pharmaceuticals, Inc. 的機構從 2025 年第 4 季到 2026 年第 1 季的變化。

2026 年第 1 季全部持有人 2025 年第 4 季全部持有人

APLS 的 13F 持有人：2025 年第 4 季與 2026 年第 1 季比較
項目	2025 年第 4 季	其中尚未申報 2026 年第 1 季	2026 年第 1 季	變化
持有家數	280	5	324	+49
股數	1.26 億	1,187 萬	1.40 億	+2,585 萬 (+22.6%)
市值	$31.7 億	$2.98 億	$55.6 億	+$26.9 億 (+93.5%)

5 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季：沒申報不算清倉，所以變化不計入它們。

新進機構（127 家）

2026 年第 1 季季末持有 Apellis Pharmaceuticals, Inc.、2025 年第 4 季季末沒有持有的機構。

依市值列出前 100 家，共 127 家。

2026 年第 1 季新進 APLS 的機構
機構	股數	市值	佔組合 %
Vanguard Portfolio Management LLC	5,404,559	$2.17 億	0.01%
Pentwater Capital Management LP	5,250,000	$2.11 億	1.50%
Vanguard Capital Management LLC	4,768,944	$1.92 億	0.00%
HBK Investments L P	3,550,000	$1.43 億	1.80%
Glazer Capital, LLC	1,294,196	$5,207 萬	1.11%
TIG Advisors, LLC	1,252,986	$5,041 萬	2.41%
Toronto Dominion Bank	1,236,436	$4,974 萬	0.10%
Healthcare of Ontario Pension Plan Trust Fund	1,202,100	$4,836 萬	0.08%
FIL Ltd	1,140,000	$4,586 萬	0.04%
Kryger Capital LLC	1,100,000	$4,425 萬	3.13%
Soros Fund Management LLC大師索羅斯基金管理	1,056,000	$4,248 萬	0.58%
Capitolis Liquid Global Markets LLC	1,013,500	$4,077 萬	0.26%
Magnetar Financial LLC	869,229	$3,497 萬	0.36%
Alpine Associates Management Inc.	864,000	$3,476 萬	2.05%
Oddo BHF Asset Management SAS	825,000	$3,319 萬	1.31%
Weiss Asset Management LP	700,000	$2,816 萬	0.52%
Vanguard Fiduciary Trust Co	654,922	$2,635 萬	0.01%
Principal Financial Group Inc	499,053	$2,008 萬	0.01%
Absolute Gestao de Investimentos Ltda.	450,000	$1,810 萬	2.07%
LMR Partners LLP	403,622	$1,624 萬	0.15%
Verition Fund Management LLC	400,000	$1,609 萬	0.16%
Public Sector Pension Investment Board	366,674	$1,475 萬	0.05%
Vivaldi Asset Management, LLC	350,800	$1,411 萬	0.74%
Gabelli Funds LLC	321,200	$1,292 萬	0.09%
Beck Bode, LLC	312,841	$1,259 萬	2.13%
Meteora Capital, LLC	300,000	$1,207 萬	0.89%
O'Connor Alternative Investments LLC	300,000	$1,207 萬	0.63%
Capstone Investment Advisors, LLC	250,000	$1,006 萬	0.08%
Westchester Capital Management, LLC	227,489	$915.2 萬	0.44%
Gabelli & Co Investment Advisers, Inc.	200,600	$807.0 萬	1.20%
Gardner Lewis Asset Management L P	165,000	$663.8 萬	1.44%
Picton Mahoney Asset Management	150,000	$603.5 萬	0.06%
CNH Partners LLC	146,604	$589.8 萬	0.10%
Chicago Capital Management, LLC	190,000	$576.1 萬	4.77%
Slotnik Capital, LLC	135,000	$543.1 萬	1.61%
Twin Securities, Inc.	127,440	$512.7 萬	2.53%
Schonfeld Strategic Advisors LLC	123,824	$498.1 萬	0.04%
Water Island Capital LLC	120,500	$484.8 萬	0.65%
Sagefield Capital LP	104,065	$418.7 萬	0.30%
Nine Masts Capital Ltd	97,478	$392.2 萬	0.61%
Prudential Financial Inc	92,510	$372.2 萬	0.00%
Caitong International Asset Management Co., Ltd	90,466	$363.9 萬	0.67%
CI Private Wealth, LLC	84,571	$340.2 萬	0.00%
Abc Arbitrage SA	83,317	$335.2 萬	0.45%
Perceptive Advisors LLC	80,956	$325.7 萬	0.06%
HGC Investment Management Inc.	75,000	$301.7 萬	0.67%
Vanguard Asset Management, Ltd	71,855	$289.1 萬	0.00%
Harvest Management LLC	70,000	$281.6 萬	1.50%
Thrivent Financial for Lutherans	68,407	$275.2 萬	0.01%
Capital Fund Management S.A.	68,112	$274.0 萬	0.02%
FNY Investment Advisers, LLC	63,092	$253.8 萬	1.13%
Jacobs Levy Equity Management, Inc	61,681	$248.1 萬	0.01%
Burney Co	61,578	$247.7 萬	0.08%
Capula Management Ltd	56,266	$226.4 萬	0.02%
One68 Global Capital, LLC	55,347	$222.7 萬	7.21%
Virtu Financial LLC	54,785	$220.4 萬	0.09%
Versor Investments LP	51,146	$205.8 萬	5.04%
State of Alaska, Department of Revenue	50,562	$203.4 萬	0.02%
TPG GP A, LLC	50,000	$201.2 萬	0.05%
CIBRA Capital Ltd	50,000	$201.2 萬	0.97%
Louisiana State Employees Retirement System	45,400	$182.6 萬	0.03%
CSS LLC	42,818	$172.3 萬	0.10%
XTX Topco Ltd	41,627	$167.5 萬	0.03%
Vanguard Global Advisers, LLC	40,745	$163.9 萬	0.00%
State of Tennessee, Treasury Department	40,180	$161.6 萬	0.01%
Fortress Investment Group LLC	40,000	$160.9 萬	0.41%
Carmignac Gestion	35,127	$141.3 萬	0.02%
Readystate Asset Management LP	34,100	$137.2 萬	0.08%
DRW Securities, LLC	33,573	$135.1 萬	0.07%
Carlson Capital L P	30,000	$120.7 萬	0.48%
Yousif Capital Management, LLC	27,997	$112.6 萬	0.01%
Commonwealth of Pennsylvania Public School Empls Retrmt Sys	25,344	$102.0 萬	0.01%
Teachers Retirement System of the State of Kentucky	25,000	$100.6 萬	0.01%
Two Sigma Securities, LLC	23,779	$95.7 萬	0.11%
Transmarket Holdings LP	23,585	$94.9 萬	0.51%
Oregon Public Employees Retirement Fund	23,400	$94.1 萬	0.01%
E Fund Management Co., Ltd.	22,686	$91.3 萬	0.03%
Fifth Third Bancorp	22,102	$88.9 萬	0.00%
Mint Tower Capital Management B.V.	22,000	$88.5 萬	0.09%
Gamco Investors, Inc. Et Al	21,000	$84.5 萬	0.01%
Maryland State Retirement & Pension System	20,816	$83.7 萬	0.02%
JBF Capital, Inc.	20,532	$82.6 萬	0.12%
SummitTX Capital, L.P.	20,351	$81.9 萬	0.03%
Clear Harbor Asset Management, LLC	20,000	$80.5 萬	0.06%
Vanguard Investments Australia, Ltd.	19,240	$77.4 萬	0.00%
Engineers Gate Manager LP	19,197	$77.2 萬	0.01%
New York State Teachers Retirement System	18,299	$73.6 萬	0.00%
GTS Securities LLC	15,604	$62.8 萬	0.02%
denkapparat Operations GmbH	13,334	$53.6 萬	0.22%
Bayesian Capital Management, LP	13,104	$52.7 萬	0.64%
Blackstone Group Inc.	12,712	$51.1 萬	0.00%
AE Wealth Management LLC	12,316	$49.5 萬	0.00%
Mutual of America Capital Management LLC	11,728	$47.2 萬	0.01%
Landing Point Financial Group, LLC	10,755	$43.3 萬	0.21%
Shay Capital LLC	10,347	$41.6 萬	0.06%
MML Investors Services, LLC	9,504	$38.2 萬	0.00%
BCK Capital Management LP	8,000	$32.2 萬	1.40%
FORA Capital, LLC	7,572	$30.5 萬	0.02%
Fifth Lane Capital, LP	7,500	$30.2 萬	0.37%
ProShare Advisors LLC	6,809	$27.4 萬	0.00%

清倉機構（78 家）

2025 年第 4 季季末持有 Apellis Pharmaceuticals, Inc.、2026 年第 1 季有申報但已經沒有持有的機構。

2026 年第 1 季清倉 APLS 的機構
機構	2025 年第 4 季股數	2025 年第 4 季市值
Polar Capital Holdings Plc	3,706,510	$9,311 萬
Siren, L.L.C.	2,578,396	$6,477 萬
OrbiMed Advisors LLC	2,429,868	$6,104 萬
Jennison Associates LLC	1,504,299	$3,779 萬
Bank of Nova Scotia	1,070,141	$2,688 萬
Simplify Asset Management Inc.	538,008	$1,351 萬
Voloridge Investment Management, LLC	461,186	$1,158 萬
Rhenman & Partners Asset Management AB	374,450	$940.6 萬
Schroder Investment Management Group	329,134	$830.7 萬
J. Goldman & Co LP	285,992	$718.4 萬
Natixis	257,268	$646.3 萬
Caption Management, LLC	254,563	$639.5 萬
Integral Health Asset Management, LLC	200,000	$502.4 萬
HRT Financial LP	192,488	$483.5 萬
Apis Capital Advisors, LLC	192,000	$482.3 萬
Silvercrest Asset Management Group LLC	190,759	$479.2 萬
California Public Employees Retirement System	186,328	$468.1 萬
HighVista Strategies LLC	150,776	$378.7 萬
DekaBank Deutsche Girozentrale	55,000	$349.7 萬
ING Groep NV	139,000	$349.2 萬
Two Sigma Advisers, LP	110,900	$278.6 萬
Algert Global LLC	109,733	$275.6 萬
Edgestream Partners, L.P.	97,443	$244.8 萬
Coppell Advisory Solutions LLC	77,390	$195.3 萬
Ikarian Capital, LLC	71,747	$180.2 萬
Jane Street Group, LLC	50,114	$125.9 萬
Ishara Investments LP	50,000	$125.6 萬
Panagora Asset Management Inc	42,134	$105.8 萬
Vontobel Holding Ltd.	34,039	$85.5 萬
Dark Forest Capital Management LP	31,091	$78.1 萬
Ieq Capital, LLC	25,500	$64.1 萬
Quadrature Capital Ltd	24,075	$60.5 萬
Cerity Partners LLC	23,971	$60.2 萬
Entropy Technologies, LP	23,128	$58.1 萬
PSP Research LLC	21,866	$54.9 萬
Diversified Trust Co	18,942	$47.6 萬
Qube Research & Technologies Ltd	18,843	$47.3 萬
Advent Capital Management	18,000	$45.2 萬
Allianz Asset Management GmbH	17,000	$42.7 萬
Brevan Howard Capital Management LP	16,117	$40.5 萬
Maven Securities LTD	15,000	$37.7 萬
GWM Advisors LLC	14,570	$36.6 萬
Nomura Holdings Inc	14,200	$35.7 萬
Pallas Capital Advisors LLC	13,885	$34.9 萬
Twinbeech Capital LP	13,152	$33.0 萬
Freestone Grove Partners LP	12,537	$31.5 萬
Quest Partners LLC	11,741	$29.5 萬
Bridgefront Capital, LLC	11,326	$28.5 萬
Arrowpoint Investment Partners (Singapore) Pte. Ltd.	10,806	$27.1 萬
Perbak Capital Partners LLP	10,217	$25.7 萬
Graham Capital Management, L.P.	9,302	$23.4 萬
Mirabella Financial Services LLP	9,078	$22.8 萬
Quantitative Investment Management, LLC	8,611	$21.6 萬
Quarry LP	5,000	$12.6 萬
Bellevue Group AG	4,210	$10.6 萬
Atlantic Private Wealth, LLC	1,000	$2.51 萬
EFG International AG	788	$1.98 萬
Aster Capital Management (DIFC) Ltd	643	$1.62 萬
Daiwa Securities Group Inc.	369	$9,000
Bessemer Group Inc	205	$5,000
Torren Management, LLC	189	$4,748
ZRC Wealth Management, LLC	151	$3,794
Massmutual Trust Co FSB	106	$2,663
Crewe Advisors LLC	88	$2,211
SRS Capital Advisors, Inc.	46	$1,156
Sunbelt Securities, Inc.	39	$980
SageView Advisory Group, LLC	35	$880
Basecamp Wealth Advisors LLC	31	$779
Turning Point Benefit Group, Inc.	27	$678
Bare Financial Services, Inc	25	$628
United Financial Planning Group LLC	24	$603
Greenline Wealth Management LLC	21	$537
South State Corp.	15	$377
Ronald Blue Trust, Inc.	14	$352
Clearstead Advisors, LLC	13	$327
Assetmark, Inc	10	$251
Rothschild Investment LLC	4	$100
Transamerica Financial Advisors, Inc.	1	$25

尚未申報 2026 年第 1 季的機構（5 家）

2025 年第 4 季季末持有 Apellis Pharmaceuticals, Inc.、還沒有申報 2026 年第 1 季 13F 的機構。沒申報不代表賣出，所以不算清倉。

2025 年第 4 季持有 APLS、尚未申報 2026 年第 1 季的機構
機構	2025 年第 4 季股數	2025 年第 4 季市值
Vanguard Group Inc	10,674,865	$2.68 億
Norges Bank	1,198,444	$3,010 萬
CIBC Private Wealth Group, LLC	343	$8,616
Comerica Bank	315	$7,913
Global Retirement Partners, LLC	41	$1,030