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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 9 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Xeris Biopharma Holdings, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
242
+7 vs. Q1 2026
Shares held
108.2M
+3.41M (+3.3%) vs. Q1 2026
Total value
$857.1M
+$248.9M (+40.9%) vs. Q1 2026
New holders
34
108 more added
Sold out
27
65 more reduced

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 242 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 227 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ2 2026: $857.1M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $120.2MQ1 2022: $129.2MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $146.7MQ3 2023: $102.3MQ4 2023: $140.8MQ1 2024: $133.7MQ2 2024: $136.6MQ3 2024: $182.2MQ4 2024: $222.2MQ1 2025: $480.9MQ2 2025: $422.9MQ3 2025: $789.3MQ4 2025: $792.0MQ1 2026: $610.3MQ2 2026: $857.1M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.1M
Q1 2026239$610.3M
Q4 2025227$792.0M
Q3 2025231$789.3M
Q2 2025201$422.9M
Q1 2025199$480.9M
Q4 2024162$222.2M
Q3 2024144$182.2M
Q2 2024135$136.6M
Q1 2024142$133.7M
Q4 2023120$140.8M
Q3 2023111$102.3M
Q2 2023105$146.7M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$129.2M
Q4 202192$120.2M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q1 2026.

Institutions holding XERS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Pictet Asset Management Holding SA29,999$237.6K0.00%00.0%Unchanged
AMG National Trust Bank30,000$237.6K0.00%+30,000New
China Universal Asset Management Co., Ltd.31,076$246.1K0.01%−11,169−26.4%Reduced
Diversified Trust Co32,062$253.9K0.00%00.0%Unchanged
Profund Advisors LLC32,711$259.1K0.01%−8,422−20.5%Reduced
Savvy Advisors, Inc.33,288$263.6K0.01%−8,180−19.7%Reduced
Intech Investment Management LLC35,108$278.1K0.00%−1,133−3.1%Reduced
Persistent Asset Partners Ltd35,661$282.4K0.09%00.0%Unchanged
Weiss Asset Management LP36,488$289.0K0.00%−13,513−27.0%Reduced
KLP Kapitalforvaltning AS36,800$291.5K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System37,970$300.7K0.00%00.0%Unchanged
Allianz Asset Management GmbH39,700$314.4K0.00%+39,700New
Vanguard Investments Australia, Ltd.40,202$318.4K0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.40,424$320.0K0.00%+5,750+16.6%Added
Cerity Partners LLC40,999$324.7K0.00%+10,416+34.1%Added
HSBC Holdings PLC41,779$329.6K0.00%+10,604+34.0%Added
Quantinno Capital Management LP42,466$336.3K0.00%+11,495+37.1%Added
XTX Topco Ltd43,190$342.1K0.00%+22,918+113.1%Added
Advisor Group Holdings, Inc.45,496$360.3K0.00%−9,260−16.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)46,100$365.1K0.00%−47,202−50.6%Reduced
Round Rock Advisors, LLC46,102$365.1K0.05%−50,714−52.4%Reduced
Arizona State Retirement System46,414$367.6K0.00%+839+1.8%Added
AlphaCentric Advisors LLC46,549$368.7K0.31%+663+1.4%Added
Mariner, LLC47,314$374.6K0.00%+24,233+105.0%Added
Wealth Enhancement Advisory Services, LLC47,228$393.9K0.00%+10,048+27.0%Added
Royal Bank of Canada49,859$394.0K0.00%+6,249+14.3%Added
Palogic Value Management, L.P.50,068$396.5K0.14%+68+0.1%Added
Police & Firemen's Retirement System of New Jersey50,576$400.6K0.00%+9,838+24.1%Added
New York State Common Retirement Fund53,722$425.5K0.00%+10,300+23.7%Added
State of New Jersey Common Pension Fund D54,389$430.8K0.00%−2,317−4.1%Reduced
Susquehanna Portfolio Strategies, LLC60,486$479.0K0.01%+60,486New
Vanguard Global Advisers, LLC61,623$488.1K0.00%−14,888−19.5%Reduced
Jane Street Group, LLC61,915$490.4K0.00%−663,701−91.5%Reduced
Penn Capital Management Co Inc62,021$491.2K0.03%−6,875−10.0%Reduced
Thompson Siegel & Walmsley LLC64,320$509.0K0.01%−22,000−25.5%Reduced
Renaissance Technologies LLC67,337$533.3K0.00%−385,523−85.1%Reduced
VARCOV Co.70,752$560.4K0.21%+70,752New
Teachers Retirement System of the State of Kentucky72,907$577.0K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The74,704$591.7K0.00%+1,900+2.6%Added
Mirae Asset Global ETFs Holdings Ltd.78,627$622.7K0.00%+4,757+6.4%Added
Western Wealth Management, LLC79,975$633.4K0.02%+4,300+5.7%Added
EntryPoint Capital, LLC80,750$639.5K0.16%−15,460−16.1%Reduced
Gsa Capital Partners LLP82,830$656.0K0.04%−18,608−18.3%Reduced
Franklin Resources Inc88,885$704.0K0.00%+8,668+10.8%Added
American Century Companies Inc93,345$739.3K0.00%+93,345New
Ieq Capital, LLC98,429$779.6K0.00%+16,799+20.6%Added
MetLife Investment Management100,167$793.3K0.00%+23,404+30.5%Added
Palo Alto Investors LP104,410$826.9K0.11%00.0%Unchanged
Alliancebernstein L.P.145,336$842.9K0.00%00.0%Unchanged
Invesco Ltd.109,875$870.2K0.00%+6,581+6.4%Added
Quantbot Technologies LP111,102$879.9K0.03%+83,038+295.9%Added
Gotham Asset Management, LLC123,914$981.4K0.00%+80,657+186.5%Added
Connor, Clark & Lunn Investment Management Ltd.127,107$1.01M0.00%−280,518−68.8%Reduced
LPL Financial LLC128,941$1.02M0.00%+35,080+37.4%Added
Millennium Management LLC131,664$1.04M0.00%−2,134,310−94.2%Reduced
Diadema Partners LP132,746$1.05M0.37%00.0%Unchanged
Vanguard Asset Management, Ltd133,417$1.06M0.00%+29,862+28.8%Added
Citigroup Inc134,298$1.06M0.00%+46,973+53.8%Added
Susquehanna International Group, LLP139,918$1.11M0.00%−146,153−51.1%Reduced
Ameriprise Financial Inc143,285$1.13M0.00%+1,137+0.8%Added
Globeflex Capital L P145,917$1.16M0.15%+22,733+18.5%Added
Quarry LP150,057$1.19M0.19%+25,057+20.0%Added
Creative Planning154,059$1.22M0.00%+20,774+15.6%Added
Wells Fargo & Company157,487$1.25M0.00%+99,180+170.1%Added
Barclays PLC166,566$1.32M0.00%+28,013+20.2%Added
Virtus Investment Advisers, Inc.171,264$1.36M0.32%+133,234+350.3%Added
CI Private Wealth, LLC184,126$1.46M0.00%+184,126New
California State Teachers Retirement System186,800$1.48M0.00%+6,461+3.6%Added
Caption Management, LLC197,863$1.57M0.06%−7,137−3.5%Reduced
Aquatic Capital Management LLC199,983$1.58M0.05%+199,983New
Raymond James Financial Inc202,911$1.61M0.00%−5,362−2.6%Reduced
Voleon Capital Management LP204,732$1.62M0.03%+158,224+340.2%Added
Commonwealth Equity Services, LLC205,855$1.63M0.00%+2,739+1.3%Added
Rhumbline Advisers214,205$1.70M0.00%+23,138+12.1%Added
Canada Pension Plan Investment Board219,200$1.74M0.00%−155,600−41.5%Reduced
Group One Trading, L.P.226,607$1.79M0.05%+8,462+3.9%Added
Principal Financial Group Inc227,418$1.80M0.00%+18,911+9.1%Added
Panagora Asset Management Inc227,579$1.80M0.01%+122,835+117.3%Added
Legato Capital Management LLC241,341$1.91M0.16%+7,197+3.1%Added
Apella Capital, LLC215,897$1.93M0.03%−20,000−8.5%Reduced
Cliffwater LLC263,158$2.08M0.52%+263,158New
Healthcare of Ontario Pension Plan Trust Fund263,537$2.09M0.00%−200,547−43.2%Reduced
Price T Rowe Associates Inc266,877$2.11M0.00%+57,843+27.7%Added
CenterBook Partners LP280,565$2.22M0.11%−968,056−77.5%Reduced
Jefferies Financial Group Inc.293,670$2.33M0.02%+205,870+234.5%Added
Rice Hall James & Associates, LLC300,791$2.38M0.12%+49,725+19.8%Added
Schonfeld Strategic Advisors LLC318,177$2.52M0.01%+21,746+7.3%Added
Swiss National Bank337,500$2.67M0.00%+9,200+2.8%Added
Trexquant Investment LP339,113$2.69M0.02%−494,104−59.3%Reduced
SEI Investments Co339,509$2.69M0.00%−239,701−41.4%Reduced
HRT Financial LP365,659$2.90M0.01%+194,557+113.7%Added
Squarepoint Ops LLC365,731$2.90M0.01%−248,819−40.5%Reduced
Y-Intercept (Hong Kong) Ltd411,346$3.26M0.06%+249,553+154.2%Added
Jupiter Topco LLC414,959$3.29M0.00%+414,959New
State of Wisconsin Investment Board427,513$3.39M0.01%+118,967+38.6%Added
BNP Paribas Arbitrage, SA430,488$3.41M0.00%+167,701+63.8%Added
Russell Investments Group, Ltd.440,731$3.49M0.00%+56,536+14.7%Added
Man Group plc455,380$3.61M0.01%+178,958+64.7%Added
Royce & Associates LP461,153$3.65M0.03%+205,066+80.1%Added
Perceptive Advisors LLC467,013$3.70M0.06%+467,013New