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Xeris Biopharma Holdings, Inc.

XERS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001867096

In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 10 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Xeris Biopharma Holdings, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
239
+17 vs. Q4 2025
Shares held
105.2M
+16.3M (+18.4%) vs. Q4 2025
Total value
$610.3M
−$87.5M (−12.5%) vs. Q4 2025
New holders
47
100 more added
Sold out
30
57 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 239 institutions
Q1 2021: 103 institutionsQ2 2021: 94 institutionsQ3 2021: 71 institutionsQ4 2021: 92 institutionsQ1 2022: 103 institutionsQ2 2022: 103 institutionsQ3 2022: 101 institutionsQ4 2022: 97 institutionsQ1 2023: 92 institutionsQ2 2023: 105 institutionsQ3 2023: 111 institutionsQ4 2023: 120 institutionsQ1 2024: 142 institutionsQ2 2024: 135 institutionsQ3 2024: 144 institutionsQ4 2024: 162 institutionsQ1 2025: 199 institutionsQ2 2025: 201 institutionsQ3 2025: 231 institutionsQ4 2025: 227 institutionsQ1 2026: 239 institutionsQ2 2026: 242 institutions
Value heldQ1 2026: $610.3M
Q1 2021: $149.7MQ2 2021: $114.9MQ3 2021: $42.9MQ4 2021: $120.2MQ1 2022: $129.2MQ2 2022: $91.3MQ3 2022: $89.3MQ4 2022: $71.6MQ1 2023: $80.6MQ2 2023: $146.7MQ3 2023: $102.3MQ4 2023: $140.8MQ1 2024: $133.7MQ2 2024: $136.6MQ3 2024: $182.2MQ4 2024: $222.2MQ1 2025: $480.9MQ2 2025: $422.9MQ3 2025: $789.3MQ4 2025: $792.0MQ1 2026: $610.3MQ2 2026: $857.1M
Institutions holding XERS and their total value by quarter
QuarterHoldersValue
Q2 2026242$857.1M
Q1 2026239$610.3M
Q4 2025227$792.0M
Q3 2025231$789.3M
Q2 2025201$422.9M
Q1 2025199$480.9M
Q4 2024162$222.2M
Q3 2024144$182.2M
Q2 2024135$136.6M
Q1 2024142$133.7M
Q4 2023120$140.8M
Q3 2023111$102.3M
Q2 2023105$146.7M
Q1 202392$80.6M
Q4 202297$71.6M
Q3 2022101$89.3M
Q2 2022103$91.3M
Q1 2022103$129.2M
Q4 202192$120.2M
Q3 202171$42.9M
Q2 202194$114.9M
Q1 2021103$149.7M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q4 2025.

Institutions holding XERS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Cambridge Investment Research Advisors, Inc.34,674$201.0K0.00%+32+0.1%Added
Persistent Asset Partners Ltd35,661$206.8K0.08%−9,948−21.8%Reduced
Intech Investment Management LLC36,241$210.2K0.00%−28,849−44.3%Reduced
KLP Kapitalforvaltning AS36,800$213.4K0.00%+3,400+10.2%Added
DRW Securities, LLC36,807$213.5K0.01%+36,807New
State Board of Administration of Florida Retirement System37,970$220.2K0.00%00.0%Unchanged
Virtus Investment Advisers, Inc.38,030$220.6K0.06%+928+2.5%Added
Wealth Enhancement Advisory Services, LLC37,180$224.6K0.00%+6,075+19.5%Added
Stonepine Capital Management, LLC40,030$232.2K0.20%+40,030New
Vanguard Investments Australia, Ltd.40,202$233.2K0.00%+40,202New
Police & Firemen's Retirement System of New Jersey40,738$236.3K0.00%00.0%Unchanged
Profund Advisors LLC41,133$238.6K0.01%+2,186+5.6%Added
Savvy Advisors, Inc.41,468$240.5K0.01%+1,003+2.5%Added
China Universal Asset Management Co., Ltd.42,245$245.0K0.02%+15,208+56.2%Added
Gotham Asset Management, LLC43,257$250.9K0.00%+7,845+22.2%Added
New York State Common Retirement Fund43,422$251.8K0.00%00.0%Unchanged
Royal Bank of Canada43,610$253.0K0.00%+4,974+12.9%Added
Cetera Investment Advisers44,397$257.5K0.00%+5,750+14.9%Added
Arizona State Retirement System45,575$264.3K0.00%+306+0.7%Added
AlphaCentric Advisors LLC45,886$266.1K0.27%+2,494+5.7%Added
Voleon Capital Management LP46,508$269.7K0.01%+46,508New
Palogic Value Management, L.P.50,000$290.0K0.13%+50,000New
Weiss Asset Management LP50,001$290.0K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.54,756$317.6K0.00%+2,471+4.7%Added
State of New Jersey Common Pension Fund D56,706$328.9K0.00%+56,706New
Prudential Financial Inc57,139$331.4K0.00%−561,810−90.8%Reduced
Wells Fargo & Company58,307$338.2K0.00%−112,489−65.9%Reduced
CWM, LLC64,180$372.2K0.00%+8,824+15.9%Added
Integrated Quantitative Investments LLC66,170$383.8K0.07%00.0%Unchanged
Penn Capital Management Co Inc68,896$399.6K0.03%+20,832+43.3%Added
Manufacturers Life Insurance Company, The72,804$422.3K0.00%+27,003+59.0%Added
Teachers Retirement System of the State of Kentucky72,907$423.0K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.73,870$428.4K0.00%+2,559+3.6%Added
Western Wealth Management, LLC75,675$438.9K0.02%00.0%Unchanged
Vanguard Global Advisers, LLC76,511$443.8K0.00%+76,511New
MetLife Investment Management76,763$445.2K0.00%−4,831−5.9%Reduced
Magnetar Financial LLC79,302$460.0K0.00%+79,302New
Franklin Resources Inc80,217$465.3K0.00%−41,211−33.9%Reduced
Ieq Capital, LLC81,630$473.5K0.00%−4,890−5.7%Reduced
Thompson Siegel & Walmsley LLC86,320$501.0K0.01%−14,564−14.4%Reduced
Citigroup Inc87,325$506.5K0.00%−11,421−11.6%Reduced
Jefferies Financial Group Inc.87,800$509.2K0.01%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)93,302$541.2K0.00%+27,535+41.9%Added
LPL Financial LLC93,861$544.4K0.00%+9,000+10.6%Added
EntryPoint Capital, LLC96,210$558.0K0.16%+28,127+41.3%Added
Round Rock Advisors, LLC96,816$561.5K0.09%00.0%Unchanged
Twinbeech Capital LP97,200$563.8K0.06%+97,200New
Gsa Capital Partners LLP101,438$588.0K0.04%+66,773+192.6%Added
Invesco Ltd.103,294$599.1K0.00%−8,836−7.9%Reduced
Vanguard Asset Management, Ltd103,555$600.6K0.00%+103,555New
Winton Group Ltd104,240$604.6K0.02%+39,643+61.4%Added
Palo Alto Investors LP104,410$605.6K0.09%+104,410New
Panagora Asset Management Inc104,744$607.5K0.00%+104,744New
Tudor Investment Corp Et Al107,414$623.0K0.00%+85,228+384.2%Added
SG Americas Securities, LLC121,911$707.0K0.00%+11,731+10.6%Added
Globeflex Capital L P123,184$714.5K0.11%00.0%Unchanged
Quarry LP125,000$725.0K0.15%+45,000+56.3%Added
Diadema Partners LP132,746$769.9K0.32%−37,822−22.2%Reduced
Creative Planning133,285$773.1K0.00%+16,747+14.4%Added
Arrowstreet Capital, Limited Partnership133,760$775.8K0.00%−81,026−37.7%Reduced
Barclays PLC138,553$803.6K0.00%−224,198−61.8%Reduced
Ameriprise Financial Inc142,148$824.5K0.00%−1,315−0.9%Reduced
Y-Intercept (Hong Kong) Ltd161,793$938.4K0.02%+71,148+78.5%Added
HRT Financial LP171,102$992.0K0.00%−161,224−48.5%Reduced
California State Teachers Retirement System180,339$1.05M0.00%+29,168+19.3%Added
Engineers Gate Manager LP185,911$1.08M0.01%+96,507+107.9%Added
Rhumbline Advisers191,067$1.11M0.00%+1,500+0.8%Added
Alliancebernstein L.P.145,336$1.14M0.00%+506+0.3%Added
Commonwealth Equity Services, LLC203,116$1.18M0.00%+5,301+2.7%Added
Caption Management, LLC205,000$1.19M0.06%+205,000New
Emerald Mutual Fund Advisers Trust207,543$1.20M0.06%+207,543New
F/M Investments LLC207,543$1.20M0.08%+207,543New
Raymond James Financial Inc208,273$1.21M0.00%−3,146−1.5%Reduced
Principal Financial Group Inc208,507$1.21M0.00%+57,948+38.5%Added
Price T Rowe Associates Inc209,034$1.21M0.00%+35,571+20.5%Added
Group One Trading, L.P.218,145$1.27M0.04%+94,584+76.5%Added
Legato Capital Management LLC234,144$1.36M0.12%−3,287−1.4%Reduced
Rice Hall James & Associates, LLC251,066$1.46M0.08%+251,066New
Royce & Associates LP256,087$1.49M0.01%+256,087New
Apella Capital, LLC235,897$1.50M0.02%−10,000−4.1%Reduced
BNP Paribas Arbitrage, SA262,787$1.52M0.00%+4,419+1.7%Added
Man Group plc276,422$1.60M0.00%+228,647+478.6%Added
Susquehanna International Group, LLP286,071$1.66M0.00%+168,716+143.8%Added
Janus Henderson Group PLC295,489$1.71M0.00%+225,602+322.8%Added
Schonfeld Strategic Advisors LLC296,431$1.72M0.01%+61,708+26.3%Added
State of Wisconsin Investment Board308,546$1.79M0.00%−48,907−13.7%Reduced
Swiss National Bank328,300$1.90M0.00%+9,900+3.1%Added
Voloridge Investment Management, LLC370,116$2.15M0.01%−441,013−54.4%Reduced
Canada Pension Plan Investment Board374,800$2.17M0.00%−15,800−4.0%Reduced
IHT Wealth Management, LLC376,476$2.18M0.05%+112,945+42.9%Added
Russell Investments Group, Ltd.384,195$2.23M0.00%+19,409+5.3%Added
Connor, Clark & Lunn Investment Management Ltd.407,625$2.36M0.01%−651,067−61.5%Reduced
Bank of New York Mellon Corp426,285$2.47M0.00%−7,977−1.8%Reduced
Renaissance Technologies LLC452,860$2.63M0.00%−166,800−26.9%Reduced
Healthcare of Ontario Pension Plan Trust Fund464,084$2.69M0.00%−73,399−13.7%Reduced
FMR LLC513,076$2.98M0.00%+73,371+16.7%Added
SEI Investments Co579,210$3.36M0.00%+179,863+45.0%Added
JPMorgan Chase & Co612,479$3.43M0.00%−282,580−31.6%Reduced
Squarepoint Ops LLC614,550$3.56M0.01%+131,718+27.3%Added
Deutsche Bank AG623,012$3.61M0.00%−317,580−33.8%Reduced