Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 8 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Xeris Biopharma Holdings, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 231
- +32 vs. Q2 2025
- Shares held
- 97.0M
- +6.99M (+7.8%) vs. Q2 2025
- Total value
- $789.3M
- +$369.1M (+87.8%) vs. Q2 2025
- New holders
- 59
- 77 more added
- Sold out
- 27
- 61 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Essex Investment Management Co LLC | 750,034 | $6.11M | 0.93% | +24,260+3.3% | Added |
| Two Sigma Advisers, LP | 893,242 | $7.27M | 0.01% | −163,537−15.5% | Reduced |
| JPMorgan Chase & Co | 905,076 | $7.37M | 0.00% | −127,186−12.3% | Reduced |
| Jane Street Group, LLC | 913,758 | $7.44M | 0.01% | +882,593+2,832.0% | Added |
| Acadian Asset Management LLC | 921,103 | $7.50M | 0.01% | +537,866+140.3% | Added |
| AQR Capital Management LLC | 983,600 | $8.01M | 0.01% | −65,393−6.2% | Reduced |
| Knott David M Jr | 1,015,000 | $8.26M | 3.46% | −45,000−4.2% | Reduced |
| Voloridge Investment Management, LLC | 1,034,553 | $8.42M | 0.03% | +40,172+4.0% | Added |
| Kennedy Capital Management, Inc. | 1,211,583 | $9.86M | 0.22% | +395,436+48.5% | Added |
| Legal & General Group Plc | 1,357,427 | $11.0M | 0.00% | −446,776−24.8% | Reduced |
| Northern Trust Corp | 1,363,129 | $11.1M | 0.00% | +69,599+5.4% | Added |
| Prudential Financial Inc | 1,434,204 | $11.7M | 0.01% | −122,425−7.9% | Reduced |
| Charles Schwab Investment Management Inc | 1,446,619 | $11.8M | 0.00% | +879,081+154.9% | Added |
| Deutsche Bank AG | 1,567,645 | $12.8M | 0.00% | +830,718+112.7% | Added |
| Bank of America Corp | 1,594,866 | $13.0M | 0.00% | −68,624−4.1% | Reduced |
| Two Sigma Investments, LP | 1,614,579 | $13.1M | 0.02% | +399,880+32.9% | Added |
| Renaissance Technologies LLC | 1,622,840 | $13.2M | 0.02% | −432,500−21.0% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 1,698,757 | $13.8M | 0.04% | +470,798+38.3% | Added |
| UBS Group AG | 1,782,734 | $14.5M | 0.00% | +1,554,869+682.4% | Added |
| Parkman Healthcare Partners LLC | 1,791,674 | $14.6M | 1.60% | −315,809−15.0% | Reduced |
| Goldman Sachs Group Inc | 1,795,455 | $14.6M | 0.00% | −476,031−21.0% | Reduced |
| Rosalind Advisors, Inc. | 1,795,766 | $14.6M | 5.31% | −359,828−16.7% | Reduced |
| Driehaus Capital Management LLC | 2,619,129 | $21.3M | 0.15% | +548,054+26.5% | Added |
| Nuveen, LLC | 2,827,874 | $23.0M | 0.01% | +227,432+8.7% | Added |
| Morgan Stanley | 3,219,701 | $26.2M | 0.00% | −422,883−11.6% | Reduced |
| Qube Research & Technologies Ltd | 3,274,834 | $26.7M | 0.04% | +185,063+6.0% | Added |
| State Street Corp | 3,738,329 | $30.4M | 0.00% | −44,871−1.2% | Reduced |
| Geode Capital Management, LLC | 4,140,174 | $33.7M | 0.00% | +489,486+13.4% | Added |
| D. E. Shaw & Co., Inc. | 5,839,886 | $47.5M | 0.04% | +2,004,479+52.3% | Added |
| Vanguard Group Inc | 9,827,917 | $80.0M | 0.00% | +10,980+0.1% | Added |
| BlackRock, Inc. | 11,927,699 | $97.1M | 0.00% | +391,378+3.4% | Added |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −880,314−100.0% | Sold out |
| Voss Capital, LLC | 0 | $0 | 0.00% | −319,800−100.0% | Sold out |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −205,100−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −181,877−100.0% | Sold out |
| Alpine Global Management, LLC | 0 | $0 | 0.00% | −150,000−100.0% | Sold out |
| Options Solutions, LLC | 0 | $0 | 0.00% | −132,994−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −130,849−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −125,417−100.0% | Sold out |
| Brown Advisory Inc | 0 | $0 | 0.00% | −114,698−100.0% | Sold out |
| Chevy Chase Trust Holdings, Inc. | 0 | $0 | 0.00% | −51,243−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −45,100−100.0% | Sold out |
| Centiva Capital, LP | 0 | $0 | 0.00% | −39,086−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −24,662−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −24,325−100.0% | Sold out |
| Apollon Wealth Management, LLC | 0 | $0 | 0.00% | −24,201−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −21,645−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −20,751−100.0% | Sold out |
| Clear Street Markets LLC | 0 | $0 | 0.00% | −14,497−100.0% | Sold out |
| Inceptionr LLC | 0 | $0 | 0.00% | −11,639−100.0% | Sold out |
| Sigma Planning Corp | 0 | $0 | 0.00% | −10,050−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −6,300−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −1,627−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −1,067−100.0% | Sold out |
| Headlands Technologies LLC | 0 | $0 | 0.00% | −1,052−100.0% | Sold out |
| Glenmede Investment Management, LP | 0 | $0 | 0.00% | −975−100.0% | Sold out |
| Bryn Mawr Trust Co | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| WealthTrak Capital Management LLC | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| Norges Bank | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |