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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q2 2025

Institutional positions in Wave Life Sciences, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
177
−17 vs. Q1 2025
Shares held
138.9M
+7.62M (+5.8%) vs. Q1 2025
Total value
$903.1M
−$158.3M (−14.9%) vs. Q1 2025
New holders
23
84 more added
Sold out
40
39 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 177 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ2 2025: $903.1M
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q1 2025.

Institutions holding WVE in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Norges Bank100,000$650.0K0.00%00.0%Unchanged
Compass Rose Asset Management, LP100,000$650.0K0.24%+100,000New
Legal & General Group Plc102,050$663.3K0.00%−13,962−12.0%Reduced
ADAR1 Capital Management, LLC114,814$746.3K0.12%+91,714+397.0%Added
Invesco Ltd.114,959$747.2K0.00%+36,079+45.7%Added
Sofinnova Investments, Inc.117,903$766.4K0.05%+117,903New
James J. Burns & Company, LLC121,913$792.4K0.13%00.0%Unchanged
Wells Fargo & Company124,667$810.3K0.00%−98,295−44.1%Reduced
Boothbay Fund Management, LLC132,891$863.8K0.03%+86,145+184.3%Added
Privium Fund Management B.V.135,550$883.8K0.19%+22,000+19.4%Added
Mirae Asset Global ETFs Holdings Ltd.145,308$944.5K0.00%+87,959+153.4%Added
New York State Common Retirement Fund150,513$978.3K0.00%00.0%Unchanged
Ikarian Capital, LLC161,137$1.05M0.35%+161,137New
Rhumbline Advisers162,599$1.06M0.00%+29,899+22.5%Added
Manufacturers Life Insurance Company, The163,699$1.06M0.00%+7,913+5.1%Added
Twinbeech Capital LP163,745$1.06M0.02%−232,303−58.7%Reduced
TD Asset Management Inc179,608$1.17M0.00%+25,200+16.3%Added
Swiss National Bank205,200$1.33M0.00%+13,200+6.9%Added
Susquehanna International Group, LLP224,426$1.46M0.00%+107,337+91.7%Added
Two Sigma Investments, LP243,167$1.58M0.00%+1,453+0.6%Added
F/M Investments LLC243,677$1.58M0.06%+3,259+1.4%Added
Nuveen, LLC249,469$1.62M0.00%+199,266+396.9%Added
Macquarie Group Ltd266,856$1.74M0.00%−5,470−2.0%Reduced
D. E. Shaw & Co., Inc.271,474$1.76M0.00%+164,920+154.8%Added
Cinctive Capital Management LP277,764$1.81M0.10%+277,764New
Dark Forest Capital Management LP280,765$1.82M0.07%+83,549+42.4%Added
Susquehanna Portfolio Strategies, LLC285,086$1.85M0.04%+270,758+1,889.7%Added
Bank of New York Mellon Corp289,282$1.88M0.00%+42,031+17.0%Added
UBS Asset Management Americas Inc295,061$1.92M0.00%+111,659+60.9%Added
Wellington Management Group LLP297,887$1.94M0.00%−1,782−0.6%Reduced
Principal Financial Group Inc302,276$1.96M0.00%−5,768−1.9%Reduced
Ensign Peak Advisors, Inc313,307$2.04M0.00%+313,307New
Baker Bros. Advisors LP344,063$2.24M0.02%00.0%Unchanged
Platinum Investment Management Ltd355,353$2.31M0.15%+43,361+13.9%Added
Universal- Beteiligungs- und Servicegesellschaft mbH358,429$2.33M0.00%−4,129−1.1%Reduced
Newtyn Management, LLC400,000$2.60M0.39%00.0%Unchanged
Moody Aldrich Partners LLC421,852$2.74M0.53%−17,975−4.1%Reduced
Woodline Partners LP452,060$2.94M0.02%00.0%Unchanged
Walleye Capital LLC467,887$3.04M0.03%+77,047+19.7%Added
Barclays PLC573,187$3.73M0.00%+311,973+119.4%Added
Qube Research & Technologies Ltd591,384$3.84M0.01%+216,520+57.8%Added
UBS Group AG607,272$3.95M0.00%+438,983+260.9%Added
FMR LLC619,137$4.02M0.00%−1,525,690−71.1%Reduced
Schroder Investment Management Group621,378$4.04M0.00%+142,109+29.7%Added
Bank of America Corp645,560$4.20M0.00%+110,295+20.6%Added
Voloridge Investment Management, LLC683,193$4.44M0.02%−87,514−11.4%Reduced
Millennium Management LLC692,415$4.50M0.00%+666,193+2,540.6%Added
RTW Investments, LP900,000$5.85M0.08%00.0%Unchanged
StemPoint Capital LP900,338$5.85M1.88%+810,505+902.2%Added
Polar Capital Holdings Plc1,003,500$6.52M0.03%00.0%Unchanged
Goldman Sachs Group Inc1,007,081$6.55M0.00%+449,437+80.6%Added
Northern Trust Corp1,008,782$6.56M0.00%+37,036+3.8%Added
Charles Schwab Investment Management Inc1,010,658$6.57M0.00%+47,533+4.9%Added
MPM Oncology Impact Management LP1,505,262$9.78M1.70%−4,318−0.3%Reduced
Morgan Stanley1,544,038$10.0M0.00%+364,111+30.9%Added
JPMorgan Chase & Co1,569,015$10.2M0.00%+390,078+33.1%Added
Pfizer Inc1,875,000$12.2M2.12%00.0%Unchanged
Emerald Mutual Fund Advisers Trust1,937,489$12.6M0.77%+6,669+0.3%Added
Affinity Asset Advisors, LLC2,000,308$13.0M1.92%+175,308+9.6%Added
Artisan Partners Limited Partnership2,264,835$14.7M0.02%−105,318−4.4%Reduced
Primecap Management Co2,465,850$16.0M0.01%−41,670−1.7%Reduced
State Street Corp2,756,755$17.9M0.00%+338,792+14.0%Added
Geode Capital Management, LLC2,759,381$17.9M0.00%+166,982+6.4%Added
Emerald Advisers, LLC3,257,119$21.2M0.78%+123,561+3.9%Added
Loomis Sayles & Co L P3,295,700$21.4M0.03%+859,160+35.3%Added
Vanguard Group Inc3,477,077$22.6M0.00%+270,674+8.4%Added
Siren, L.L.C.3,696,322$24.0M1.24%00.0%Unchanged
Bellevue Group AG4,094,458$26.6M0.59%00.0%Unchanged
683 Capital Management, LLC4,100,000$26.7M2.70%+175,000+4.5%Added
Kynam Capital Management, LP4,560,053$29.6M3.19%−339,444−6.9%Reduced
Price T Rowe Associates Inc5,190,403$33.7M0.00%+1,065,112+25.8%Added
M28 Capital Management LP5,664,548$36.8M62.80%00.0%Unchanged
Driehaus Capital Management LLC6,531,519$42.5M0.34%+172,920+2.7%Added
Maverick Capital LtdSuperinvestorMaverick Capital8,261,683$53.7M0.82%00.0%Unchanged
BlackRock, Inc.10,383,716$67.5M0.00%+755,104+7.8%Added
Adage Capital Partners GP, L.L.C.15,016,500$97.6M0.16%+2,500,000+20.0%Added
Ra Capital Management, L.P.18,202,009$118.3M1.99%00.0%Unchanged
Silverarc Capital Management, LLC0$00.00%−1,050,374−100.0%Sold out
Trexquant Investment LP0$00.00%−223,412−100.0%Sold out
EAM Investors, LLC0$00.00%−213,848−100.0%Sold out
Renaissance Technologies LLC0$00.00%−210,220−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−126,046−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−109,330−100.0%Sold out
Hussman Strategic Advisors, Inc.0$00.00%−105,000−100.0%Sold out
Atom Investors LP0$00.00%−98,798−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−76,926−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−71,741−100.0%Sold out
PDT Partners, LLC0$00.00%−55,918−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−47,299−100.0%Sold out
Caption Management, LLC0$00.00%−43,501−100.0%Sold out
Jump Financial, LLC0$00.00%−41,761−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−39,395−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−35,691−100.0%Sold out
Maven Securities LTD0$00.00%−35,000−100.0%Sold out
Wealthedge Investment Advisors, LLC0$00.00%−29,572−100.0%Sold out
XTX Topco Ltd0$00.00%−27,792−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−27,380−100.0%Sold out
Capula Management Ltd0$00.00%−26,486−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−25,249−100.0%Sold out
Massar Capital Management, LP0$00.00%−21,356−100.0%Sold out