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Sionna Therapeutics, Inc.

SION
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002036042

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.11B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Sionna Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
146
+25 vs. Q1 2026
Shares held
48.1M
+2.68M (+5.9%) vs. Q1 2026
Total value
$2.11B
+$294.2M (+16.2%) vs. Q1 2026
New holders
34
58 more added
Sold out
9
39 more reduced

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SION on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 146 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 47 institutionsQ2 2025: 65 institutionsQ3 2025: 78 institutionsQ4 2025: 101 institutionsQ1 2026: 122 institutionsQ2 2026: 146 institutions
Value heldQ2 2026: $2.11B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $434.1MQ2 2025: $753.8MQ3 2025: $1.26BQ4 2025: $1.81BQ1 2026: $1.82BQ2 2026: $2.11B
Institutions holding SION and their total value by quarter
QuarterHoldersValue
Q2 2026146$2.11B
Q1 2026122$1.82B
Q4 2025101$1.81B
Q3 202578$1.26B
Q2 202565$753.8M
Q1 202547$434.1M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Sionna Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding SION in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
First Turn Management, LLC110,493$4.86M0.52%+110,493New
UBS Group AG116,206$5.11M0.00%−31,435−21.3%Reduced
Artia Global Partners LP119,741$5.27M1.00%00.0%Unchanged
Vanguard Fiduciary Trust Co121,442$5.34M0.00%+9,267+8.3%Added
Sio Capital Management, LLC127,808$5.62M0.96%−166,532−56.6%Reduced
Charles Schwab Investment Management Inc129,753$5.71M0.00%+9,500+7.9%Added
GordonMD Global Investments LP136,000$5.98M3.28%00.0%Unchanged
Alyeska Investment Group, L.P.136,222$5.99M0.02%00.0%Unchanged
Qube Research & Technologies Ltd140,309$6.17M0.01%+98,067+232.2%Added
Sofinnova Investments, Inc.144,432$6.35M0.34%+144,432New
Morgan Stanley151,047$6.64M0.00%+18,024+13.5%Added
Northern Trust Corp154,476$6.80M0.00%+37,700+32.3%Added
Soleus Capital Management, L.P.177,687$7.82M0.27%−115,813−39.5%Reduced
Ensign Peak Advisors, Inc184,532$8.12M0.01%−71,104−27.8%Reduced
Artisan Partners Limited Partnership189,498$8.34M0.01%+189,498New
Longaeva Partners L.P.196,352$8.64M0.25%+183,659+1,446.9%Added
Kalehua Capital Management LLC197,072$8.67M4.98%00.0%Unchanged
Vanguard Portfolio Management LLC222,949$9.81M0.00%+80,868+56.9%Added
Candriam Luxembourg S.C.A.233,208$10.2M0.05%−3,605−1.5%Reduced
Millennium Management LLC276,733$12.2M0.01%+136,092+96.8%Added
FMR LLC278,292$12.2M0.00%+196,897+241.9%Added
Standard Life Aberdeen plc284,138$12.5M0.02%−280,037−49.6%Reduced
Franklin Resources Inc290,113$12.8M0.00%+114,630+65.3%Added
Driehaus Capital Management LLC385,447$17.0M0.10%+308,814+403.0%Added
Goldman Sachs Group Inc388,810$17.1M0.00%+125,636+47.7%Added
Baker Bros. Advisors LP400,000$17.6M0.09%00.0%Unchanged
Casdin Capital, LLC400,000$17.6M0.88%+400,000New
Geode Capital Management, LLC457,145$20.1M0.00%+67,273+17.3%Added
Eventide Asset Management, LLC474,981$20.9M0.28%−170,549−26.4%Reduced
Price T Rowe Associates Inc478,016$21.0M0.00%−278,360−36.8%Reduced
Siren, L.L.C.610,515$26.9M0.55%+310,515+103.5%Added
Deerfield Management Company, L.P. (Series C)680,916$30.0M0.31%−289,674−29.8%Reduced
Perceptive Advisors LLC905,000$39.8M0.62%+246,561+37.4%Added
State Street Corp1,021,534$44.9M0.00%+265,307+35.1%Added
Vanguard Capital Management LLC1,132,001$49.8M0.00%+102,504+10.0%Added
Citadel Advisors LLC1,147,636$50.5M0.03%−19,295−1.7%Reduced
Jennison Associates LLC1,172,133$51.6M0.03%−279,087−19.2%Reduced
JPMorgan Chase & Co1,490,508$64.1M0.00%+25,494+1.7%Added
BlackRock, Inc.1,474,769$64.9M0.00%+178,902+13.8%Added
Adage Capital Partners GP, L.L.C.1,600,000$70.4M0.10%+1,450,000+966.7%Added
Enavate Sciences GP, LLC2,478,030$109.0M31.56%00.0%Unchanged
OrbiMed Advisors LLC2,555,877$112.4M2.13%−974,825−27.6%Reduced
Atlas Venture Life Science Advisors, LLC2,995,602$131.8M14.95%00.0%Unchanged
Viking Global Investors LPSuperinvestorViking Global Investors3,195,181$140.6M0.40%00.0%Unchanged
TPG GP A, LLC6,494,962$285.7M5.71%00.0%Unchanged
Ra Capital Management, L.P.9,905,045$435.7M3.79%00.0%Unchanged
Polen Capital Management LLC0$00.00%−26,775−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−7,310−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−7,190−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−6,180−100.0%Sold out
Two Sigma Investments, LP0$00.00%−5,500−100.0%Sold out
Cygnus Capital Advisors, LLC0$00.00%−3,800−100.0%Sold out
Signaturefd, LLC0$00.00%−24−100.0%Sold out
Root Financial Partners, LLC0$00.00%−10−100.0%Sold out
MAI Capital Management0$00.00%−2−100.0%Sold out
CWM, LLC––––Not filed