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Sionna Therapeutics, Inc.

SION
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002036042

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.11B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q2 2025

Institutional positions in Sionna Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
65
+18 vs. Q1 2025
Shares held
43.4M
+1.96M (+4.7%) vs. Q1 2025
Total value
$753.8M
+$319.8M (+73.7%) vs. Q1 2025
New holders
26
18 more added
Sold out
8
10 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SION on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 65 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 47 institutionsQ2 2025: 65 institutionsQ3 2025: 78 institutionsQ4 2025: 101 institutionsQ1 2026: 122 institutionsQ2 2026: 146 institutions
Value heldQ2 2025: $753.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $434.1MQ2 2025: $753.8MQ3 2025: $1.26BQ4 2025: $1.81BQ1 2026: $1.82BQ2 2026: $2.11B
Institutions holding SION and their total value by quarter
QuarterHoldersValue
Q2 2026146$2.11B
Q1 2026122$1.82B
Q4 2025101$1.81B
Q3 202578$1.26B
Q2 202565$753.8M
Q1 202547$434.1M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Sionna Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding SION in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Sterling Capital Management LLC30$5210.00%+30New
Hughes Financial Services, LLC44$7470.00%+44New
Royal Bank of Canada60$1.00K0.00%−558−90.3%Reduced
Amalgamated Bank421$7.00K0.00%+421New
California State Teachers Retirement System770$13.4K0.00%+770New
Ameritas Investment Partners, Inc.1,259$21.8K0.00%+1,259New
Legal & General Group Plc1,374$23.8K0.00%+1,374New
BNP Paribas Arbitrage, SA1,761$30.6K0.00%+1,761New
STRS Ohio2,300$39.9K0.00%+2,300New
Police & Firemen's Retirement System of New Jersey2,608$45.2K0.00%+2,608New
Citigroup Inc4,380$76.0K0.00%+4,380New
Virtus Investment Advisers, Inc.5,535$96.0K0.03%+5,535New
Bank of America Corp6,012$104.3K0.00%−2,727−31.2%Reduced
Wells Fargo & Company6,374$110.6K0.00%+6,374New
Mirae Asset Global ETFs Holdings Ltd.6,747$117.1K0.00%+6,747New
New York State Common Retirement Fund6,800$118.0K0.00%+6,800New
MetLife Investment Management8,033$139.4K0.00%+8,033New
Deutsche Bank AG9,596$166.5K0.00%+9,596New
Commonwealth Equity Services, LLC14,017$243.0K0.00%+14,017New
Millennium Management LLC14,034$243.5K0.00%−165,038−92.2%Reduced
Susquehanna International Group, LLP14,834$257.4K0.00%+14,834New
Nuveen, LLC16,040$278.3K0.00%+16,040New
Polen Capital Management LLC16,975$294.5K0.00%+16,975New
Options Solutions, LLC16,975$294.5K0.11%+16,975New
Rhumbline Advisers17,670$306.6K0.00%+17,670New
Barclays PLC23,022$399.4K0.00%+23,022New
Bank of New York Mellon Corp24,131$418.7K0.00%+24,131New
Renaissance Technologies LLC26,000$451.1K0.00%+26,000New
Manufacturers Life Insurance Company, The38,038$660.0K0.00%+4,489+13.4%Added
Morgan Stanley44,018$763.7K0.00%+40,079+1,017.5%Added
Goldman Sachs Group Inc46,048$798.9K0.00%−17,693−27.8%Reduced
TD Asset Management Inc49,966$866.9K0.00%−5,400−9.8%Reduced
Holocene Advisors, LP50,000$867.5K0.00%00.0%Unchanged
UBS Group AG51,367$891.2K0.00%+40,221+360.9%Added
Woodline Partners LP80,000$1.39M0.01%00.0%Unchanged
Driehaus Capital Management LLC83,850$1.45M0.01%−245,039−74.5%Reduced
Northern Trust Corp91,890$1.59M0.00%+65,068+242.6%Added
Charles Schwab Investment Management Inc92,832$1.61M0.00%+28,188+43.6%Added
Rock Springs Capital Management LP99,429$1.73M0.11%00.0%Unchanged
State Street Corp124,518$2.16M0.00%+110,118+764.7%Added
Citadel Advisors LLC129,912$2.25M0.00%−196,588−60.2%Reduced
Prudential Financial Inc135,185$2.35M0.00%+72,185+114.6%Added
Silverarc Capital Management, LLC186,015$3.23M0.66%+71,877+63.0%Added
Alyeska Investment Group, L.P.186,222$3.23M0.01%00.0%Unchanged
Ameriprise Financial Inc236,813$4.11M0.00%+27,547+13.2%Added
Geode Capital Management, LLC289,275$5.02M0.00%+153,712+113.4%Added
Siren, L.L.C.325,000$5.64M0.29%00.0%Unchanged
Soleus Capital Management, L.P.376,000$6.52M0.45%+136,000+56.7%Added
Baker Bros. Advisors LP400,000$6.94M0.07%00.0%Unchanged
Franklin Resources Inc500,023$8.68M0.00%00.0%Unchanged
Vanguard Group Inc630,351$10.9M0.00%+84,184+15.4%Added
BlackRock, Inc.637,104$11.1M0.00%+438,708+221.1%Added
Jennison Associates LLC752,800$13.1M0.01%−107,127−12.5%Reduced
Price T Rowe Associates Inc861,238$14.9M0.00%−134,974−13.5%Reduced
Standard Life Aberdeen plc950,547$16.5M0.03%+204,583+27.4%Added
Deerfield Management Company, L.P. (Series C)970,590$16.8M0.31%+223,590+29.9%Added
Braidwell LP1,081,855$18.8M0.64%+1,081,855New
Perceptive Advisors LLC1,216,045$21.1M0.79%−35,056−2.8%Reduced
JPMorgan Chase & Co2,221,188$38.5M0.00%+51,589+2.4%Added
Enavate Sciences GP, LLC2,478,030$43.0M24.35%00.0%Unchanged
Viking Global Investors LPSuperinvestorViking Global Investors3,195,181$55.4M0.16%+242,427+8.2%Added
Atlas Venture Life Science Advisors, LLC3,694,020$64.1M9.68%00.0%Unchanged
OrbiMed Advisors LLC3,704,959$64.3M1.62%00.0%Unchanged
TPG GP A, LLC6,744,962$117.0M6.24%+60,000+0.9%Added
Ra Capital Management, L.P.10,445,322$181.2M3.05%00.0%Unchanged
Zimmer Partners, LP0$00.00%−237,500−100.0%Sold out
CenterBook Partners LP0$00.00%−114,284−100.0%Sold out
StemPoint Capital LP0$00.00%−60,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−33,964−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−14,757−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−13,060−100.0%Sold out
Marshall Wace, LLP0$00.00%−12,188−100.0%Sold out
Two Sigma Investments, LP0$00.00%−11,715−100.0%Sold out