Protalix BioTherapeutics, Inc.
PLX- Exchange
- NYSE
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001006281
No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Protalix BioTherapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 100
- +18 vs. Q4 2025
- Shares held
- 16.9M
- +2.45M (+17.0%) vs. Q4 2025
- Total value
- $36.6M
- +$10.6M (+40.9%) vs. Q4 2025
- New holders
- 27
- 28 more added
- Sold out
- 9
- 20 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 101 | $33.7M |
| Q1 2026 | 100 | $36.6M |
| Q4 2025 | 83 | $26.8M |
| Q3 2025 | 77 | $31.0M |
| Q2 2025 | 63 | $17.6M |
| Q1 2025 | 63 | $21.0M |
| Q4 2024 | 46 | $8.40M |
| Q3 2024 | 45 | $3.53M |
| Q2 2024 | 66 | $6.60M |
| Q1 2024 | 64 | $12.4M |
| Q4 2023 | 66 | $18.1M |
| Q3 2023 | 61 | $15.2M |
| Q2 2023 | 66 | $17.9M |
| Q1 2023 | 34 | $6.15M |
| Q4 2022 | 26 | $4.87M |
| Q3 2022 | 27 | $3.70M |
| Q2 2022 | 30 | $1.30M |
| Q1 2022 | 32 | $1.29M |
| Q4 2021 | 31 | $2.52M |
| Q3 2021 | 35 | $5.91M |
| Q2 2021 | 33 | $8.71M |
| Q1 2021 | 38 | $39.4M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Protalix BioTherapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 3,616,962 | $7.85M | 0.00% | −30,144−0.8% | Reduced |
| Mak Capital One LLC | 3,544,139 | $7.69M | 1.27% | +3,544,139 | New |
| Renaissance Technologies LLC | 1,224,800 | $2.66M | 0.00% | −38,500−3.0% | Reduced |
| State Street Corp | 972,815 | $2.11M | 0.00% | +387,554+66.2% | Added |
| Northern Trust Corp | 885,448 | $1.92M | 0.00% | +19,740+2.3% | Added |
| Geode Capital Management, LLC | 865,298 | $1.88M | 0.00% | +35,244+4.2% | Added |
| Stratos Wealth Partners, LTD. | 500,000 | $1.08M | 0.01% | 00.0% | Unchanged |
| Vanguard Portfolio Management LLC | 432,485 | $938.5K | 0.00% | +432,485 | New |
| Prospera Financial Services Inc | 418,570 | $908.3K | 0.01% | +418,570 | New |
| Opaleye Management Inc. | 340,000 | $737.8K | 0.10% | −2,138,176−86.3% | Reduced |
| Morgan Stanley | 301,793 | $654.9K | 0.00% | +169,806+128.7% | Added |
| Dimensional Fund Advisors LP | 296,843 | $643.8K | 0.00% | +268,099+932.7% | Added |
| UBS Group AG | 265,535 | $576.2K | 0.00% | +3,015+1.1% | Added |
| Goldman Sachs Group Inc | 251,345 | $545.4K | 0.00% | −11,464−4.4% | Reduced |
| Bank of New York Mellon Corp | 219,307 | $475.9K | 0.00% | +8,440+4.0% | Added |
| Main Street Financial Solutions, LLC | 214,100 | $464.6K | 0.03% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 207,275 | $449.8K | 0.00% | −24,818−10.7% | Reduced |
| Round Rock Advisors, LLC | 192,080 | $416.8K | 0.06% | +36,978+23.8% | Added |
| Bridgeway Capital Management, LLC | 189,100 | $410.3K | 0.01% | 00.0% | Unchanged |
| Evergreen Capital Management LLC | 171,338 | $371.8K | 0.01% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 159,311 | $345.7K | 0.00% | −15,759−9.0% | Reduced |
| Diametric Capital, LP | 124,195 | $269.5K | 0.07% | −14,734−10.6% | Reduced |
| Nuveen, LLC | 90,188 | $195.7K | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 86,617 | $188.0K | 0.00% | +15,224+21.3% | Added |
| Bank of America Corp | 79,079 | $171.6K | 0.00% | +32,727+70.6% | Added |
| Deutsche Bank AG | 74,985 | $162.7K | 0.00% | +74,139+8,763.5% | Added |
| Virtu Financial LLC | 67,893 | $147.0K | 0.01% | +67,893 | New |
| Orin Green Financial, LLC | 64,433 | $139.8K | 0.06% | +3,000+4.9% | Added |
| Vanguard Fiduciary Trust Co | 63,351 | $137.5K | 0.00% | +63,351 | New |
| Price T Rowe Associates Inc | 53,478 | $117.0K | 0.00% | +18,200+51.6% | Added |
| Susquehanna International Group, LLP | 49,085 | $106.5K | 0.00% | +10,567+27.4% | Added |
| Invesco Ltd. | 47,402 | $102.9K | 0.00% | −3,161−6.3% | Reduced |
| Rhumbline Advisers | 45,817 | $99.4K | 0.00% | +1,448+3.3% | Added |
| MetLife Investment Management | 43,697 | $94.8K | 0.00% | +43,697 | New |
| Phoenix Holdings Ltd. | 40,000 | $86.7K | 0.00% | +40,000 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 34,062 | $73.9K | 0.00% | +816+2.5% | Added |
| New York State Common Retirement Fund | 31,100 | $67.5K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 31,685 | $66.2K | 0.00% | +811+2.6% | Added |
| AQR Capital Management LLC | 30,493 | $66.2K | 0.00% | +30,493 | New |
| Aptus Capital Advisors, LLC | 27,231 | $59.1K | 0.00% | +621+2.3% | Added |
| Wells Fargo & Company | 26,522 | $57.6K | 0.00% | −52,480−66.4% | Reduced |
| Capital Performance Advisors LLP | 26,051 | $56.5K | 0.00% | +76+0.3% | Added |
| Smartleaf Asset Management LLC | 25,975 | $54.3K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 22,671 | $49.2K | 0.00% | +22,671 | New |
| State of Alaska, Department of Revenue | 21,831 | $47.0K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 19,958 | $43.3K | 0.00% | −11,175−35.9% | Reduced |
| Manufacturers Life Insurance Company, The | 19,528 | $42.4K | 0.00% | +1,030+5.6% | Added |
| Commonwealth Equity Services, LLC | 19,461 | $42.2K | 0.00% | −152,311−88.7% | Reduced |
| Prelude Capital Management, LLC | 18,900 | $41.0K | 0.00% | −3,343−15.0% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 18,554 | $40.3K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 18,129 | $39.3K | 0.00% | +18,129 | New |
| BNP Paribas Arbitrage, SA | 17,343 | $37.6K | 0.00% | +322+1.9% | Added |
| Jane Street Group, LLC | 17,342 | $37.6K | 0.00% | −272,575−94.0% | Reduced |
| Lido Advisors, LLC | 15,554 | $33.8K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 14,822 | $32.2K | 0.00% | −98,027−86.9% | Reduced |
| Group One Trading, L.P. | 13,222 | $28.7K | 0.00% | +13,222 | New |
| Russell Investments Group, Ltd. | 12,250 | $26.6K | 0.00% | +4,983+68.6% | Added |
| Cascade Financial Partners, LLC | 12,000 | $26.0K | 0.00% | 00.0% | Unchanged |
| Neuberger Berman Group LLC | 11,629 | $25.2K | 0.00% | +11,629 | New |
| Voya Investment Management LLC | 11,494 | $24.9K | 0.00% | +11,494 | New |
| ProShare Advisors LLC | 10,589 | $23.0K | 0.00% | −2,548−19.4% | Reduced |
| LPL Financial LLC | 10,291 | $22.3K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 10,110 | $21.9K | 0.00% | +10,110 | New |
| Harbour Investment Management LLC | 10,100 | $21.9K | 0.01% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 10,000 | $21.7K | 0.00% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 11,720 | $21.1K | 0.00% | 00.0% | Unchanged |
| Equitable Holdings, Inc. | 11,150 | $20.1K | 0.00% | 00.0% | Unchanged |
| Altshuler Shaham Ltd | 7,742 | $16.8K | 0.00% | −4,400−36.2% | Reduced |
| Royal Bank of Canada | 7,568 | $16.0K | 0.00% | +4,164+122.3% | Added |
| Ameritas Investment Partners, Inc. | 7,119 | $15.4K | 0.00% | 00.0% | Unchanged |
| Baader Bank INC | 10,046 | $14.4K | 0.00% | +10,046 | New |
| Legal & General Group Plc | 6,333 | $13.7K | 0.00% | −868−12.1% | Reduced |
| TD Waterhouse Canada Inc. | 6,000 | $13.0K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 6,000 | $13.0K | 0.00% | +6,000 | New |
| Tower Research Capital LLC (TRC) | 5,158 | $11.2K | 0.00% | −1,075−17.2% | Reduced |
| California State Teachers Retirement System | 3,909 | $8.48K | 0.00% | −534−12.0% | Reduced |
| Citigroup Inc | 2,958 | $6.42K | 0.00% | +1,324+81.0% | Added |
| FMR LLC | 2,905 | $6.30K | 0.00% | +590+25.5% | Added |
| National Bank of Canada | 2,000 | $4.36K | 0.00% | +2,000 | New |
| CWM, LLC | 1,534 | $3.33K | 0.00% | +1,331+655.7% | Added |
| Investment Research & Advisory Group, Inc. | 1,000 | $2.17K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 479 | $1.04K | 0.00% | +124+34.9% | Added |
| Sterling Capital Management LLC | 453 | $983 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 300 | $651 | 0.00% | −900−75.0% | Reduced |
| Activest Wealth Management | 300 | $651 | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 250 | $543 | 0.00% | 00.0% | Unchanged |
| C M Bidwell & Associates Ltd | 236 | $512 | 0.00% | +236 | New |
| Y.D. More Investments Ltd | 220 | $477 | 0.00% | 00.0% | Unchanged |
| Root Financial Partners, LLC | 128 | $278 | 0.00% | +128 | New |
| Northwestern Mutual Wealth Management Co | 100 | $217 | 0.00% | +100 | New |
| SRS Capital Advisors, Inc. | 55 | $120 | 0.00% | +16+41.0% | Added |
| MAI Capital Management | 29 | $63 | 0.00% | +29 | New |
| Allworth Financial LP | 26 | $57 | 0.00% | +26 | New |
| Essential Partners LLC | 26 | $56 | 0.00% | +26 | New |
| The PNC Financial Services Group, Inc. | 20 | $43 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 15 | $33 | 0.00% | +15 | New |
| EverSource Wealth Advisors, LLC | 11 | $24 | 0.00% | +11 | New |
| True Wealth Design, LLC | 11 | $24 | 0.00% | +11 | New |
| IFP Advisors, Inc | 3 | $7 | 0.00% | +3 | New |
| SBI Securities Co., Ltd. | 1 | $2 | 0.00% | 00.0% | Unchanged |