Protalix BioTherapeutics, Inc.
PLX- Exchange
- NYSE
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001006281
No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Protalix BioTherapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 77
- +14 vs. Q2 2025
- Shares held
- 14.0M
- +2.05M (+17.2%) vs. Q2 2025
- Total value
- $31.0M
- +$13.4M (+75.7%) vs. Q2 2025
- New holders
- 17
- 18 more added
- Sold out
- 3
- 20 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 101 | $33.7M |
| Q1 2026 | 100 | $36.6M |
| Q4 2025 | 83 | $26.8M |
| Q3 2025 | 77 | $31.0M |
| Q2 2025 | 63 | $17.6M |
| Q1 2025 | 63 | $21.0M |
| Q4 2024 | 46 | $8.40M |
| Q3 2024 | 45 | $3.53M |
| Q2 2024 | 66 | $6.60M |
| Q1 2024 | 64 | $12.4M |
| Q4 2023 | 66 | $18.1M |
| Q3 2023 | 61 | $15.2M |
| Q2 2023 | 66 | $17.9M |
| Q1 2023 | 34 | $6.15M |
| Q4 2022 | 26 | $4.87M |
| Q3 2022 | 27 | $3.70M |
| Q2 2022 | 30 | $1.30M |
| Q1 2022 | 32 | $1.29M |
| Q4 2021 | 31 | $2.52M |
| Q3 2021 | 35 | $5.91M |
| Q2 2021 | 33 | $8.71M |
| Q1 2021 | 38 | $39.4M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Protalix BioTherapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 3,551,028 | $7.88M | 0.00% | +181,358+5.4% | Added |
| Opaleye Management Inc. | 2,580,556 | $5.73M | 0.81% | +2,580,556 | New |
| Renaissance Technologies LLC | 1,315,400 | $2.92M | 0.00% | −299,603−18.6% | Reduced |
| Northern Trust Corp | 902,459 | $2.00M | 0.00% | −177,264−16.4% | Reduced |
| Geode Capital Management, LLC | 819,777 | $1.82M | 0.00% | −6,556−0.8% | Reduced |
| Stratos Wealth Partners, LTD. | 500,000 | $1.11M | 0.01% | +150,000+42.9% | Added |
| State Street Corp | 498,547 | $1.11M | 0.00% | +54,308+12.2% | Added |
| Vanguard Group Inc | 464,421 | $1.03M | 0.00% | −20,377−4.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 400,398 | $888.9K | 0.00% | −95,818−19.3% | Reduced |
| UBS Group AG | 190,276 | $422.4K | 0.00% | +115,126+153.2% | Added |
| Bridgeway Capital Management, LLC | 189,100 | $419.8K | 0.01% | 00.0% | Unchanged |
| Diametric Capital, LP | 179,984 | $399.6K | 0.15% | +36,712+25.6% | Added |
| Charles Schwab Investment Management Inc | 175,070 | $388.7K | 0.00% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 171,772 | $381.0K | 0.00% | −25,025−12.7% | Reduced |
| Evergreen Capital Management LLC | 171,338 | $380.4K | 0.01% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 150,829 | $334.8K | 0.00% | +48,651+47.6% | Added |
| Bank of New York Mellon Corp | 138,548 | $307.6K | 0.00% | +4,261+3.2% | Added |
| Main Street Financial Solutions, LLC | 129,100 | $286.6K | 0.02% | +129,100 | New |
| Barclays PLC | 101,798 | $226.0K | 0.00% | −25,165−19.8% | Reduced |
| Nuveen, LLC | 90,188 | $200.2K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 85,841 | $190.6K | 0.01% | +12,166+16.5% | Added |
| Susquehanna International Group, LLP | 72,922 | $161.9K | 0.00% | −225,645−75.6% | Reduced |
| Morgan Stanley | 71,037 | $157.7K | 0.00% | −391,006−84.6% | Reduced |
| Wolverine Trading, LLC | 70,394 | $152.1K | 0.00% | +45,886+187.2% | Added |
| Deutsche Bank AG | 65,617 | $145.7K | 0.00% | +65,617 | New |
| Rhumbline Advisers | 65,194 | $144.7K | 0.00% | −4,602−6.6% | Reduced |
| Orin Green Financial, LLC | 61,200 | $135.9K | 0.05% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 59,982 | $133.2K | 0.00% | +25,437+73.6% | Added |
| Prelude Capital Management, LLC | 49,791 | $110.5K | 0.01% | −6,264−11.2% | Reduced |
| Invesco Ltd. | 45,003 | $99.9K | 0.00% | −138−0.3% | Reduced |
| Wells Fargo & Company | 42,831 | $95.1K | 0.00% | +6,797+18.9% | Added |
| New York State Common Retirement Fund | 41,300 | $91.7K | 0.00% | −27,700−40.1% | Reduced |
| State of Wyoming | 39,018 | $86.6K | 0.01% | +39,018 | New |
| Citadel Advisors LLC | 37,306 | $82.8K | 0.00% | +37,306 | New |
| Price T Rowe Associates Inc | 35,278 | $79.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 32,253 | $71.6K | 0.00% | −5,822−15.3% | Reduced |
| Intech Investment Management LLC | 31,248 | $69.4K | 0.00% | −5,242−14.4% | Reduced |
| Capital Performance Advisors LLP | 25,975 | $57.7K | 0.01% | −10.0% | Reduced |
| Aptus Capital Advisors, LLC | 25,727 | $57.1K | 0.00% | +874+3.5% | Added |
| Manufacturers Life Insurance Company, The | 24,054 | $53.4K | 0.00% | +24,054 | New |
| Bank of America Corp | 20,119 | $44.7K | 0.00% | −1,773−8.1% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 18,554 | $41.2K | 0.00% | 00.0% | Unchanged |
| Cascade Financial Partners, LLC | 17,000 | $37.7K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 17,028 | $37.5K | 0.00% | −28,543−62.6% | Reduced |
| Virtu Financial LLC | 16,530 | $37.0K | 0.00% | +16,530 | New |
| Lido Advisors, LLC | 15,554 | $34.5K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 15,215 | $33.8K | 0.00% | +8,498+126.5% | Added |
| Altshuler Shaham Ltd | 12,142 | $27.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 11,922 | $26.5K | 0.00% | −2,375−16.6% | Reduced |
| Alliancebernstein L.P. | 11,720 | $26.0K | 0.00% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 11,000 | $24.4K | 0.00% | +11,000 | New |
| Two Sigma Advisers, LP | 10,300 | $22.9K | 0.00% | +10,300 | New |
| LPL Financial LLC | 10,291 | $22.8K | 0.00% | +10,291 | New |
| Harbour Investment Management LLC | 10,100 | $22.4K | 0.01% | 00.0% | Unchanged |
| Legal & General Group Plc | 7,757 | $17.2K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 7,465 | $16.6K | 0.00% | +7,465 | New |
| Ameritas Investment Partners, Inc. | 7,119 | $15.8K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 6,614 | $14.7K | 0.00% | −18,142−73.3% | Reduced |
| TD Waterhouse Canada Inc. | 6,000 | $14.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 5,513 | $12.2K | 0.00% | +5,386+4,240.9% | Added |
| California State Teachers Retirement System | 4,353 | $9.66K | 0.00% | +3+0.1% | Added |
| Simplex Trading, LLC | 2,942 | $6.00K | 0.00% | +2,942 | New |
| Truvestments Capital LLC | 2,458 | $5.46K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 2,381 | $5.00K | 0.00% | 00.0% | Unchanged |
| Investment Research & Advisory Group, Inc. | 1,000 | $2.22K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 1,073 | $2.00K | 0.00% | +487+83.1% | Added |
| Advisor Group Holdings, Inc. | 700 | $1.29K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 438 | $972 | 0.00% | +438 | New |
| Activest Wealth Management | 300 | $666 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 296 | $658 | 0.00% | +296 | New |
| Federation des caisses Desjardins du Quebec | 250 | $555 | 0.00% | 00.0% | Unchanged |
| Y.D. More Investments Ltd | 220 | $488 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 201 | $446 | 0.00% | +1+0.5% | Added |
| Sterling Capital Management LLC | 169 | $375 | 0.00% | +1+0.6% | Added |
| The PNC Financial Services Group, Inc. | 35 | $78 | 0.00% | +35 | New |
| Steward Partners Investment Advisory, LLC | 25 | $56 | 0.00% | +25 | New |
| CWM, LLC | 163 | $0 | 0.00% | +163 | New |
| Hillsdale Investment Management Inc. | 0 | $0 | 0.00% | −118,100−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −71,537−100.0% | Sold out |
| Harel Insurance Investments & Financial Services Ltd. | 0 | $0 | 0.00% | −26,000−100.0% | Sold out |