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Protalix BioTherapeutics, Inc.

PLX
Exchange
NYSE
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001006281

No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Protalix BioTherapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
63
0 vs. Q1 2025
Shares held
11.9M
+3.72M (+45.5%) vs. Q1 2025
Total value
$17.6M
−$3.33M (−15.9%) vs. Q1 2025
New holders
30
20 more added
Sold out
30
3 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 63 institutions
Q1 2021: 38 institutionsQ2 2021: 33 institutionsQ3 2021: 35 institutionsQ4 2021: 31 institutionsQ1 2022: 32 institutionsQ2 2022: 30 institutionsQ3 2022: 27 institutionsQ4 2022: 26 institutionsQ1 2023: 34 institutionsQ2 2023: 66 institutionsQ3 2023: 61 institutionsQ4 2023: 66 institutionsQ1 2024: 64 institutionsQ2 2024: 66 institutionsQ3 2024: 45 institutionsQ4 2024: 46 institutionsQ1 2025: 63 institutionsQ2 2025: 63 institutionsQ3 2025: 77 institutionsQ4 2025: 83 institutionsQ1 2026: 100 institutionsQ2 2026: 101 institutions
Value heldQ2 2025: $17.6M
Q1 2021: $39.4MQ2 2021: $8.71MQ3 2021: $5.91MQ4 2021: $2.52MQ1 2022: $1.29MQ2 2022: $1.30MQ3 2022: $3.70MQ4 2022: $4.87MQ1 2023: $6.15MQ2 2023: $17.9MQ3 2023: $15.2MQ4 2023: $18.1MQ1 2024: $12.4MQ2 2024: $6.60MQ3 2024: $3.53MQ4 2024: $8.40MQ1 2025: $21.0MQ2 2025: $17.6MQ3 2025: $31.0MQ4 2025: $26.8MQ1 2026: $36.6MQ2 2026: $33.7M
Institutions holding PLX and their total value by quarter
QuarterHoldersValue
Q2 2026101$33.7M
Q1 2026100$36.6M
Q4 202583$26.8M
Q3 202577$31.0M
Q2 202563$17.6M
Q1 202563$21.0M
Q4 202446$8.40M
Q3 202445$3.53M
Q2 202466$6.60M
Q1 202464$12.4M
Q4 202366$18.1M
Q3 202361$15.2M
Q2 202366$17.9M
Q1 202334$6.15M
Q4 202226$4.87M
Q3 202227$3.70M
Q2 202230$1.30M
Q1 202232$1.29M
Q4 202131$2.52M
Q3 202135$5.91M
Q2 202133$8.71M
Q1 202138$39.4M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Protalix BioTherapeutics, Inc.; share changes are against Q1 2025.

Institutions holding PLX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.3,369,670$4.99M0.00%+3,115,135+1,223.9%Added
Renaissance Technologies LLC1,615,003$2.39M0.00%+426,050+35.8%Added
Northern Trust Corp1,079,723$1.60M0.00%+394,965+57.7%Added
Geode Capital Management, LLC826,333$1.22M0.00%+826,333New
Connor, Clark & Lunn Investment Management Ltd.496,216$734.4K0.00%+13,341+2.8%Added
Vanguard Group Inc484,798$717.5K0.00%+484,798New
Morgan Stanley462,043$683.8K0.00%+378,485+453.0%Added
State Street Corp444,239$657.5K0.00%+444,239New
Stratos Wealth Partners, LTD.350,000$518.0K0.01%+3,600+1.0%Added
Susquehanna International Group, LLP298,567$441.9K0.00%−560,083−65.2%Reduced
Commonwealth Equity Services, LLC196,797$291.0K0.00%+146,772+293.4%Added
Bridgeway Capital Management, LLC189,100$279.9K0.01%00.0%Unchanged
Charles Schwab Investment Management Inc175,070$259.1K0.00%+175,070New
Evergreen Capital Management LLC171,338$253.6K0.01%+171,338New
Diametric Capital, LP143,272$212.0K0.11%+143,272New
Bank of New York Mellon Corp134,287$198.7K0.00%+134,287New
Barclays PLC126,963$187.9K0.00%+102,653+422.3%Added
Hillsdale Investment Management Inc.118,100$174.8K0.01%+2,000+1.7%Added
Goldman Sachs Group Inc102,178$151.2K0.00%−187,283−64.7%Reduced
Nuveen, LLC90,188$133.5K0.00%+90,188New
UBS Group AG75,150$111.2K0.00%+73,063+3,500.9%Added
XTX Topco Ltd73,675$109.0K0.00%+31,849+76.1%Added
Two Sigma Investments, LP71,537$105.9K0.00%−14,817−17.2%Reduced
Rhumbline Advisers69,796$103.3K0.00%+69,796New
New York State Common Retirement Fund69,000$102.1K0.00%+69,000New
Orin Green Financial, LLC61,200$90.6K0.04%+11,200+22.4%Added
Prelude Capital Management, LLC56,055$83.0K0.01%+56,055New
Dimensional Fund Advisors LP45,571$67.7K0.00%+45,571New
Invesco Ltd.45,141$66.8K0.00%+45,141New
Mirae Asset Global ETFs Holdings Ltd.38,075$56.4K0.00%+38,075New
Intech Investment Management LLC36,490$54.0K0.00%+36,490New
Wells Fargo & Company36,034$53.3K0.00%+36,034New
Price T Rowe Associates Inc35,278$53.0K0.00%+35,278New
JPMorgan Chase & Co34,545$51.1K0.00%+32,950+2,065.8%Added
Harel Insurance Investments & Financial Services Ltd.26,000$40.0K0.00%+26,000New
Capital Performance Advisors LLP25,976$38.4K0.01%00.0%Unchanged
Wolverine Trading, LLC24,508$37.7K0.00%+24,508New
Aptus Capital Advisors, LLC24,853$36.8K0.00%+915+3.8%Added
Citigroup Inc24,756$36.6K0.00%+22,464+980.1%Added
Bank of America Corp21,892$32.4K0.00%+21,886+364,766.7%Added
Police & Firemen's Retirement System of New Jersey18,554$27.5K0.00%+18,554New
Cascade Financial Partners, LLC17,000$25.2K0.00%+17,000New
Lido Advisors, LLC15,554$23.0K0.00%00.0%Unchanged
ProShare Advisors LLC14,297$21.2K0.00%+14,297New
Altshuler Shaham Ltd12,142$18.0K0.00%00.0%Unchanged
Alliancebernstein L.P.11,720$17.3K0.00%+11,720New
Harbour Investment Management LLC10,100$14.9K0.01%00.0%Unchanged
Legal & General Group Plc7,757$11.5K0.00%+7,757New
Ameritas Investment Partners, Inc.7,119$10.5K0.00%+7,119New
BNP Paribas Arbitrage, SA6,717$9.94K0.00%+6,016+858.2%Added
TD Waterhouse Canada Inc.6,000$8.76K0.00%00.0%Unchanged
California State Teachers Retirement System4,350$6.44K0.00%+4,350New
Amalgamated Bank2,381$4.00K0.00%+2,381New
Truvestments Capital LLC2,458$3.64K0.00%00.0%Unchanged
Investment Research & Advisory Group, Inc.1,000$1.48K0.00%+400+66.7%Added
Advisor Group Holdings, Inc.700$1.04K0.00%+300+75.0%Added
Activest Wealth Management300$4440.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec250$3700.00%00.0%Unchanged
Y.D. More Investments Ltd220$3250.00%00.0%Unchanged
SBI Securities Co., Ltd.200$2960.00%+150+300.0%Added
Sterling Capital Management LLC168$2490.00%+168New
Tower Research Capital LLC (TRC)127$1880.00%+127New
Royal Bank of Canada586$00.00%+586New
Millennium Management LLC0$00.00%−963,011−100.0%Sold out
Marshall Wace, LLP0$00.00%−615,085−100.0%Sold out
Jane Street Group, LLC0$00.00%−294,318−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−209,292−100.0%Sold out
Omers Administration Corp0$00.00%−179,300−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−163,058−100.0%Sold out
Squarepoint Ops LLC0$00.00%−120,786−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−118,808−100.0%Sold out
Jain Global LLC0$00.00%−81,963−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−76,063−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.0$00.00%−54,174−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−53,380−100.0%Sold out
Quantessence Capital LLC0$00.00%−51,243−100.0%Sold out
LMR Partners LLP0$00.00%−49,025−100.0%Sold out
Kestra Advisory Services, LLC0$00.00%−44,500−100.0%Sold out
Prudential Financial Inc0$00.00%−36,400−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−33,015−100.0%Sold out
Creative Planning0$00.00%−32,740−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−27,139−100.0%Sold out
HSBC Holdings PLC0$00.00%−25,535−100.0%Sold out
Capula Management Ltd0$00.00%−15,690−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−15,336−100.0%Sold out
Raymond James Financial Inc0$00.00%−15,174−100.0%Sold out
GWM Advisors LLC0$00.00%−15,080−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−13,474−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−12,000−100.0%Sold out
Acadian Asset Management LLC0$00.00%−9,691−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−5,623−100.0%Sold out
Citadel Advisors LLC0$00.00%−2,818−100.0%Sold out
Lazard Asset Management LLC0$00.00%−797−100.0%Sold out