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Protalix BioTherapeutics, Inc.

PLX
Exchange
NYSE
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001006281

No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Protalix BioTherapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
46
+1 vs. Q3 2024
Shares held
4.40M
+960.2K (+28.0%) vs. Q3 2024
Total value
$8.40M
+$4.87M (+138.0%) vs. Q3 2024
New holders
8
12 more added
Sold out
7
8 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 46 institutions
Q1 2021: 38 institutionsQ2 2021: 33 institutionsQ3 2021: 35 institutionsQ4 2021: 31 institutionsQ1 2022: 32 institutionsQ2 2022: 30 institutionsQ3 2022: 27 institutionsQ4 2022: 26 institutionsQ1 2023: 34 institutionsQ2 2023: 66 institutionsQ3 2023: 61 institutionsQ4 2023: 66 institutionsQ1 2024: 64 institutionsQ2 2024: 66 institutionsQ3 2024: 45 institutionsQ4 2024: 46 institutionsQ1 2025: 63 institutionsQ2 2025: 63 institutionsQ3 2025: 77 institutionsQ4 2025: 83 institutionsQ1 2026: 100 institutionsQ2 2026: 101 institutions
Value heldQ4 2024: $8.40M
Q1 2021: $39.4MQ2 2021: $8.71MQ3 2021: $5.91MQ4 2021: $2.52MQ1 2022: $1.29MQ2 2022: $1.30MQ3 2022: $3.70MQ4 2022: $4.87MQ1 2023: $6.15MQ2 2023: $17.9MQ3 2023: $15.2MQ4 2023: $18.1MQ1 2024: $12.4MQ2 2024: $6.60MQ3 2024: $3.53MQ4 2024: $8.40MQ1 2025: $21.0MQ2 2025: $17.6MQ3 2025: $31.0MQ4 2025: $26.8MQ1 2026: $36.6MQ2 2026: $33.7M
Institutions holding PLX and their total value by quarter
QuarterHoldersValue
Q2 2026101$33.7M
Q1 2026100$36.6M
Q4 202583$26.8M
Q3 202577$31.0M
Q2 202563$17.6M
Q1 202563$21.0M
Q4 202446$8.40M
Q3 202445$3.53M
Q2 202466$6.60M
Q1 202464$12.4M
Q4 202366$18.1M
Q3 202361$15.2M
Q2 202366$17.9M
Q1 202334$6.15M
Q4 202226$4.87M
Q3 202227$3.70M
Q2 202230$1.30M
Q1 202232$1.29M
Q4 202131$2.52M
Q3 202135$5.91M
Q2 202133$8.71M
Q1 202138$39.4M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Protalix BioTherapeutics, Inc.; share changes are against Q3 2024.

Institutions holding PLX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Renaissance Technologies LLC1,118,000$2.10M0.00%+162,100+17.0%Added
Northern Trust Corp731,742$1.38M0.00%+679,451+1,299.4%Added
Millennium Management LLC387,921$729.3K0.00%+14,164+3.8%Added
Gsa Capital Partners LLP305,749$575.0K0.04%−129,464−29.7%Reduced
Stratos Wealth Partners, LTD.270,000$507.6K0.01%00.0%Unchanged
BlackRock, Inc.224,657$422.4K0.00%+45,873+25.7%Added
Bridgeway Capital Management, LLC181,400$341.0K0.01%−2,390−1.3%Reduced
Morgan Stanley170,216$320.0K0.00%+127,158+295.3%Added
Citadel Advisors LLC145,787$274.1K0.00%+54,129+59.1%Added
Jane Street Group, LLC113,616$213.6K0.00%+67,664+147.2%Added
Marshall Wace, LLP101,899$191.6K0.00%+101,899New
Squarepoint Ops LLC73,940$139.0K0.00%+18,522+33.4%Added
Orin Green Financial, LLC–$135.4K0.06%––
Point72 Asia (Singapore) Pte. Ltd.53,507$100.6K0.03%+6,434+13.7%Added
Commonwealth Equity Services, LLC50,000$94.0K0.00%00.0%Unchanged
Goldman Sachs Group Inc49,710$93.5K0.00%−531−1.1%Reduced
HSBC Holdings PLC40,023$75.6K0.00%00.0%Unchanged
Prudential Financial Inc36,400$68.4K0.00%+36,400New
Barclays PLC34,323$64.5K0.00%00.0%Unchanged
Virtu Financial LLC34,276$64.0K0.00%−9,112−21.0%Reduced
Bank of America Corp33,714$63.4K0.00%−11,280−25.1%Reduced
Cubist Systematic Strategies, LLC29,307$55.1K0.00%+5,686+24.1%Added
Capital Performance Advisors LLP25,976$48.8K0.02%00.0%Unchanged
Qube Research & Technologies Ltd24,867$46.8K0.00%−11,571−31.8%Reduced
Aptus Capital Advisors, LLC23,363$43.9K0.00%+1,026+4.6%Added
PFG Investments, LLC20,730$39.0K0.00%+20,730New
Y-Intercept (Hong Kong) Ltd18,818$35.4K0.00%+18,818New
UBS Group AG18,178$34.2K0.00%+17,886+6,125.3%Added
Lido Advisors, LLC15,554$29.2K0.00%00.0%Unchanged
Kestra Advisory Services, LLC14,000$26.3K0.00%−2,000−12.5%Reduced
Altshuler Shaham Ltd12,142$22.8K0.00%00.0%Unchanged
Catalyst Funds Management Pty Ltd10,200$19.2K0.00%00.0%Unchanged
Harbour Investment Management LLC10,100$19.0K0.01%00.0%Unchanged
TD Waterhouse Canada Inc.6,000$11.1K0.00%00.0%Unchanged
Truvestments Capital LLC2,458$4.62K0.00%00.0%Unchanged
JPMorgan Chase & Co1,595$3.00K0.00%00.0%Unchanged
Lazard Asset Management LLC1,255$2.00K0.00%+1,255New
Point72 (DIFC) Ltd901$1.69K0.00%−10,699−92.2%Reduced
BNP Paribas Arbitrage, SA716$1.35K0.00%+716New
Group One Trading, L.P.656$1.23K0.00%+656New
Citigroup Inc632$1.19K0.00%+632New
Activest Wealth Management300$5640.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec250$4700.00%00.0%Unchanged
Y.D. More Investments Ltd220$4140.00%00.0%Unchanged
Advisor Group Holdings, Inc.200$3760.00%00.0%Unchanged
SRS Capital Advisors, Inc.39$740.00%00.0%Unchanged
Susquehanna International Group, LLP0$00.00%−70,817−100.0%Sold out
Sanctuary Advisors, LLC0$00.00%−37,100−100.0%Sold out
XTX Topco Ltd0$00.00%−35,058−100.0%Sold out
Finivi Inc.0$00.00%−14,544−100.0%Sold out
National Bank of Canada0$00.00%−6,000−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−5,055−100.0%Sold out
Simplex Trading, LLC0$00.00%−3,414−100.0%Sold out