Protalix BioTherapeutics, Inc.
PLX- Exchange
- NYSE
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001006281
No open-market purchases or sales by Protalix BioTherapeutics, Inc. insiders were filed in the last 90 days; 101 institutions reported holding it in 13F filings for Q2 2026, worth $33.7M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Protalix BioTherapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 77
- +14 vs. Q2 2025
- Shares held
- 13.9M
- +2.02M (+17.0%) vs. Q2 2025
- Total value
- $30.9M
- +$13.3M (+75.4%) vs. Q2 2025
- New holders
- 17
- 17 more added
- Sold out
- 3
- 21 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 101 | $33.7M |
| Q1 2026 | 100 | $36.6M |
| Q4 2025 | 83 | $26.8M |
| Q3 2025 | 77 | $30.9M |
| Q2 2025 | 63 | $17.6M |
| Q1 2025 | 63 | $21.0M |
| Q4 2024 | 46 | $8.40M |
| Q3 2024 | 45 | $3.53M |
| Q2 2024 | 66 | $6.60M |
| Q1 2024 | 64 | $11.9M |
| Q4 2023 | 66 | $17.6M |
| Q3 2023 | 61 | $15.2M |
| Q2 2023 | 66 | $17.9M |
| Q1 2023 | 34 | $6.15M |
| Q4 2022 | 26 | $4.87M |
| Q3 2022 | 27 | $3.70M |
| Q2 2022 | 30 | $1.30M |
| Q1 2022 | 32 | $1.29M |
| Q4 2021 | 31 | $2.45M |
| Q3 2021 | 35 | $5.91M |
| Q2 2021 | 33 | $8.24M |
| Q1 2021 | 38 | $39.4M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Protalix BioTherapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 163 | $0 | 0.00% | +163 | New |
| Steward Partners Investment Advisory, LLC | 25 | $56 | 0.00% | +25 | New |
| The PNC Financial Services Group, Inc. | 35 | $78 | 0.00% | +35 | New |
| Sterling Capital Management LLC | 169 | $375 | 0.00% | +1+0.6% | Added |
| SBI Securities Co., Ltd. | 201 | $446 | 0.00% | +1+0.5% | Added |
| Y.D. More Investments Ltd | 220 | $488 | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 250 | $555 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 296 | $658 | 0.00% | +296 | New |
| Activest Wealth Management | 300 | $666 | 0.00% | 00.0% | Unchanged |
| FMR LLC | 438 | $972 | 0.00% | +438 | New |
| Advisor Group Holdings, Inc. | 700 | $1.29K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 1,073 | $2.00K | 0.00% | +780+266.2% | Added |
| Investment Research & Advisory Group, Inc. | 1,000 | $2.22K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 2,381 | $5.00K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 2,458 | $5.46K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 2,942 | $6.00K | 0.00% | +2,942 | New |
| California State Teachers Retirement System | 4,353 | $9.66K | 0.00% | +3+0.1% | Added |
| Tower Research Capital LLC (TRC) | 5,513 | $12.2K | 0.00% | +5,386+4,240.9% | Added |
| TD Waterhouse Canada Inc. | 6,000 | $14.0K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 6,614 | $14.7K | 0.00% | −18,142−73.3% | Reduced |
| Ameritas Investment Partners, Inc. | 7,119 | $15.8K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 7,465 | $16.6K | 0.00% | +7,465 | New |
| Legal & General Group Plc | 7,757 | $17.2K | 0.00% | 00.0% | Unchanged |
| Harbour Investment Management LLC | 10,100 | $22.4K | 0.01% | 00.0% | Unchanged |
| LPL Financial LLC | 10,291 | $22.8K | 0.00% | +10,291 | New |
| Two Sigma Advisers, LP | 10,300 | $22.9K | 0.00% | +10,300 | New |
| Kestra Advisory Services, LLC | 11,000 | $24.4K | 0.00% | +11,000 | New |
| Alliancebernstein L.P. | 11,720 | $26.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 11,922 | $26.5K | 0.00% | −2,375−16.6% | Reduced |
| Altshuler Shaham Ltd | 12,142 | $27.0K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 15,215 | $33.8K | 0.00% | +8,498+126.5% | Added |
| Lido Advisors, LLC | 15,554 | $34.5K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 16,530 | $37.0K | 0.00% | +16,530 | New |
| Dimensional Fund Advisors LP | 17,028 | $37.5K | 0.00% | −28,543−62.6% | Reduced |
| Cascade Financial Partners, LLC | 17,000 | $37.7K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 18,554 | $41.2K | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 20,119 | $44.7K | 0.00% | −1,773−8.1% | Reduced |
| Manufacturers Life Insurance Company, The | 24,054 | $53.4K | 0.00% | +24,054 | New |
| Aptus Capital Advisors, LLC | 25,727 | $57.1K | 0.00% | +874+3.5% | Added |
| Capital Performance Advisors LLP | 25,975 | $57.7K | 0.01% | −10.0% | Reduced |
| JPMorgan Chase & Co | 29,991 | $66.6K | 0.00% | −4,554−13.2% | Reduced |
| Intech Investment Management LLC | 31,248 | $69.4K | 0.00% | −5,242−14.4% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 32,253 | $71.6K | 0.00% | −5,822−15.3% | Reduced |
| Price T Rowe Associates Inc | 35,278 | $79.0K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 37,306 | $82.8K | 0.00% | +37,306 | New |
| State of Wyoming | 39,018 | $86.6K | 0.01% | +39,018 | New |
| New York State Common Retirement Fund | 41,300 | $91.7K | 0.00% | −27,700−40.1% | Reduced |
| Wells Fargo & Company | 42,831 | $95.1K | 0.00% | +6,797+18.9% | Added |
| Invesco Ltd. | 45,003 | $99.9K | 0.00% | −138−0.3% | Reduced |
| Prelude Capital Management, LLC | 49,791 | $110.5K | 0.01% | −6,264−11.2% | Reduced |
| Orin Green Financial, LLC | 61,200 | $135.9K | 0.05% | 00.0% | Unchanged |
| Rhumbline Advisers | 65,194 | $144.7K | 0.00% | −4,602−6.6% | Reduced |
| Deutsche Bank AG | 65,617 | $145.7K | 0.00% | +65,617 | New |
| Wolverine Trading, LLC | 70,394 | $152.1K | 0.00% | +45,886+187.2% | Added |
| Morgan Stanley | 71,037 | $157.7K | 0.00% | −391,006−84.6% | Reduced |
| Susquehanna International Group, LLP | 72,922 | $161.9K | 0.00% | −225,645−75.6% | Reduced |
| XTX Topco Ltd | 85,841 | $190.6K | 0.01% | +12,166+16.5% | Added |
| Nuveen, LLC | 90,188 | $200.2K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 101,798 | $226.0K | 0.00% | −25,165−19.8% | Reduced |
| Main Street Financial Solutions, LLC | 129,100 | $286.6K | 0.02% | +129,100 | New |
| Bank of New York Mellon Corp | 138,548 | $307.6K | 0.00% | +4,261+3.2% | Added |
| Goldman Sachs Group Inc | 150,829 | $334.8K | 0.00% | +48,651+47.6% | Added |
| Evergreen Capital Management LLC | 171,338 | $380.4K | 0.01% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 171,772 | $381.0K | 0.00% | −25,025−12.7% | Reduced |
| Charles Schwab Investment Management Inc | 175,070 | $388.7K | 0.00% | 00.0% | Unchanged |
| Diametric Capital, LP | 179,984 | $399.6K | 0.15% | +36,712+25.6% | Added |
| Bridgeway Capital Management, LLC | 189,100 | $419.8K | 0.01% | 00.0% | Unchanged |
| UBS Group AG | 190,276 | $422.4K | 0.00% | +115,126+153.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 400,398 | $888.9K | 0.00% | −95,818−19.3% | Reduced |
| Vanguard Group Inc | 464,421 | $1.03M | 0.00% | −20,377−4.2% | Reduced |
| State Street Corp | 498,547 | $1.11M | 0.00% | +54,308+12.2% | Added |
| Stratos Wealth Partners, LTD. | 500,000 | $1.11M | 0.01% | +150,000+42.9% | Added |
| Geode Capital Management, LLC | 819,777 | $1.82M | 0.00% | −6,556−0.8% | Reduced |
| Northern Trust Corp | 902,459 | $2.00M | 0.00% | −177,264−16.4% | Reduced |
| Renaissance Technologies LLC | 1,315,400 | $2.92M | 0.00% | −299,603−18.6% | Reduced |
| Opaleye Management Inc. | 2,580,556 | $5.73M | 0.81% | +2,580,556 | New |
| BlackRock, Inc. | 3,551,028 | $7.88M | 0.00% | +181,358+5.4% | Added |
| Hillsdale Investment Management Inc. | 0 | $0 | 0.00% | −118,100−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −71,537−100.0% | Sold out |
| Harel Insurance Investments & Financial Services Ltd. | 0 | $0 | 0.00% | −26,000−100.0% | Sold out |